IntroductionTo explore the relationship between teachers’ job burnout and big five personality traits through meta-analysis.MethodsChinese and foreign databases, such as China Knowledge Network Infrastructure (CNKI), VIP Database, Wanfang database, Chinese excellent master’s degree full text, Science Direct, Web of science, Wiley online library, Springer link, Taylor & Francis, and APA PsycNET, were searched, and the relevant literature was collected and screened for meta-analysis.ResultsA total of 28 literatures were included, and the total sample size was 12,103. Meta-analysis showed that the dimensions of emotional exhaustion and depersonalization were moderately negatively correlated with conscientiousness, openness, extroversion, and agreeableness, and the effect values were −0.20 (−0.26 ∼−0.13), −0.11 (−0.17 ∼−0.05), −0.18 (−0.24 ∼−0.12), −0.14 (−0.22 ∼−0.06), −0.27 (−0.33 ∼−0.22), −0.12 (−0.16 ∼−0.08), −0.19 (−0.24 ∼−0.14), and −0.28 (−0.36 ∼−0.19), respectively. The effect values were 0.30 (0.21 ∼ 0.40) and 0.26 (0.17 ∼ 0.34). The dimension of low sense of achievement was negatively correlated with the five dimensions of conscientiousness, openness, neuroticism, extroversion and agreeableness of the big five personality traits, and the influence values were −0.02 (−0.18 ∼ 0.13), −0.02 (−0.14 ∼ 0.10), −0.03 (−0.16 ∼ 0.10), −0.04 (−0.18 ∼ 0.19), −0.05 (−0.16 ∼ 0.06) respectively. The correlation between each dimension of big five personality traits and each dimension of teachers’ job burnout is adjusted by teaching segment, region, big five personality traits scale, and publication age.ConclusionThe dimensions of emotional exhaustion and depersonalization are negatively correlated with conscientiousness, openness, extroversion, and agreeableness, and positively correlated with neuroticism. The dimension of low personal achievement is negatively correlated with the dimensions of big five personality traits. According to the results of this study, teachers generally have the problem of job burnout, and their personality characteristics have a significant impact on job burnout. School managers should pay attention to this problem and implement necessary interventions. At the same time, the conclusions of this study also provide some guiding significance for teachers’ career development.