Prime Source Research Articles

Hydroxycinnamic Acid Extraction from Multiple Lignocellulosic Sources: Correlations with Substrate Composition and Taxonomy for Flavoring and Antioxidant Applications.

The extraction of hydroxycinnamic acids (HCADs) is a strategy for lignocellulosic biomass valorization due to their high value-added nature and the possibility of application as flavoring and antioxidants. This study proposes correlations between the composition and taxonomy of 28 globally available agro-industrial feedstocks with the production of HCADs using chemometric tools. Principal component analysis indicated strong correlations between ferulic acid release and hemicellulose type and content, especially in grass biomasses. Conversely, p-coumaric acid release was mainly correlated with cellulose content across diverse taxonomic origins. Among the evaluated agro-industrial feedstocks, corn-based biomasses were identified as prime sources of ferulic acid after mild alkaline treatment, releasing up to 10.5 g kg-1 and producing hydrolysates with an antioxidant capacity up to 3.3 mmol Trolox equivalents g-1. Notably, sugar cane bagasse was the best source of p-coumaric acid, yielding 4.8 g kg-1. Corn hydrolysates were successfully converted into 4-vinylguaiacol using a genetically modified Saccharomyces cerevisiae strain, achieving high yields of 0.75 g L-1. This work enhances our understanding of HCAD sources and biomass valorization strategies, demonstrating potential applications in the food and cosmetics sectors.

Comprehensive analysis of water and sediment from holy water body ‘Pokhri’ reveals presence of biomolecules that may educe skin, gastroenterological and neurological dysfunction

‘Pokhri mai’ refers to the natural pond amidst the hilly forest slopes of the Buxa tiger reserve (BTR) nearby Jayanti considered to be sacred by the local ethnic groups serving as the prime source of water for wild animals and occasionally by neighbouring inhabitants. However, the water body is designated to be noxious by a group of native people with no scientific validation. This paper focuses to explore its toxicity status and allied environmental concerns through Pokhri water and sediment sample analysis through physicochemical assessment, in vitro antioxidant assay, microbiological investigation followed by AAS, GC–MS and in silico study. pH of soil and water samples were found to be quite high (>6.8) with organic matter, carbon and available nitrogen content being 1.5308 ± 0.28 %, 0.89 ± 0.17 % and 0.072 ± 0.34 % respectively. Profuse microbial growths were observed in both sediment and water samples with consortia obtained exhibiting tolerance against a range of antifungals and antibiotics. Inhibition zone was absent for sediment consortium whereas consortium of water samples portrayed susceptibility against various heavy metals viz. Cu2+, Pb2+, Zn2+, Fe3+ and Al3+ salts with corresponding AAS quantified values of sediment samples being 133, 223.3, 86.8, 1449 and 481.5 ppm. A summative of 18 metabolites were identified by GC–MS in Pokhri lake sediment among which 13 (occupying 96.35 % peak area) were investigated to be potentially toxic with 2,4-Di-tert-butylphenol (53.38 %) as the major compound. Biomolecular characterization, ADMET test and molecular docking study with dermal, gastrointestinal and neural peptides exhibiting high binding affinity scores (ranging between −2.6 to −8.3 kcal/mol) further affirmed the toxicity attributes of the GC–MS deciphered molecules. The findings clearly justifies the local ‘myth’ of Pokhri water to be deleterious with prospective dermatotoxic, neurotoxic and being evident of gastrointestinal toxicity emphasizing ecological risk to the environment, wildlife and microflora of the adjoining forests.

Multiwavelength investigations of PKS 2300−18: S-shaped radio quasar with precessing jets and double peaked broad emission line spectrum

Abstract S-shaped radio galaxy jets are prime sources for investigating the dynamic interplay between the central active galactic nucleus, the jets, and the ambient intergalactic medium. These sources are excellent candidates for studying jet precession, as their S-shaped inversion symmetry strongly indicates underlying precession. We present a multiwavelength analysis of the giant inversion-symmetric S-shaped radio galaxy PKS 2300−18, which spans 0.76 Mpc. The host is a quasar at a redshift of 0.128, displaying disturbed optical morphology due to an ongoing merger with a companion galaxy. We conducted a broadband radio spectral study using multifrequency data ranging from 183 MHz to 6 GHz, incorporating dedicated observations with the uGMRT and JVLA alongside archival radio data. Particle injection model was fitted to the spectra of different regions of the source to perform ageing analysis, which was supplemented with a kinematic jet precession model. The ageing analysis revealed a maximum plasma age of ∼ 40 Myr, while the jet precession model indicated a precession period of ∼ 12 Myr. ROSAT data revealed an X-ray halo of Mpc size, and from Chandra the AGN X-ray spectrum was modelled using thermal and power law components. The optical spectrum displaying double peaked broad emission lines was modelled, indicating complex broad line region kinematics at the centre with the possibility of a binary SMBH. We present the results of our multiwavelength analysis of the source, spanning scales from a few light days to a few Mpc, and discuss its potential evolutionary path.

Antioxidant Valorization of PLE Extracts from Macroalgae (Cladophora glomerata): In Vitro Assessment of Nanoemulsions Against Oxidative Stress.

Driven by a growing global interest in natural products, macroalgae have emerged as a prime source for nutraceuticals and pharmaceutical applications. In the current research, the effect of oven-drying (OD) and freeze-drying (FD), as well as the pressurized liquid extraction (PLE) conditions, were investigated in relation to the polyphenols, flavonoids, carotenoids, chlorophylls, and tocochromanols levels in Cladophora glomerata extracts. The ethanol-water extracts (1:1) obtained with PLE-150 °C from macroalgae oven-dried (OD)-80 °C displayed the highest total polyphenol content (TPC) and total flavonoid contents (TFCs), reaching 29.62 mg GAE/g and 5.92 mg QE/g. Aqueous extracts using PLE-200 °C were also an excellent environmentally friendly option for TPC and TFC isolation, which were the main factors accounting for the ABTS, DPPH, and FRAP antioxidant activity of the extracts. The remarkable effects of drying conditions positively affect the carotenoids, chlorophyll α-tocopherol, and α-tocotrienol levels from extracts showing 1.3-6 times higher amounts in extracts of Cladophora glomerata OD at 80 °C compared with other research approaches. Nanotechnology approaches allowed the formulation of antioxidant-loaded nanoemulsions from Cladophora glomerata extracts, providing stability and a great internalization rate that ameliorates to 85% the ROS levels, attenuating the oxidative stress induced by H2O2 in J774.1 macrophage cell line.

Unraveling the Role of Contaminants Reshaping the Microflora in Zea mays Seeds from Heavy Metal–Contaminated and Pristine Environment

Heavy metal (HM) contaminants are the emerging driving force for reshaping the microflora of plants by eradicating the non-tolerance and non-resistant microbes via their lethal effects. Seeds served as a prime source of ancestral microbial diversity hereditary transfer from generation to generation. However, the problem arises when they got exposed to metal contamination, does metal pollutant disrupt the delicate balance of microbial communities within seeds and lead to shifts in their microflora across generations. In this study, the endophytic community within Zea mays seeds was compared across three distinct regions in Yunnan province, China: a HM-contaminated site Ayika (AK), less-contaminated site Sanduoduo (SD), and a non-contaminated Site Dali (DL). High-throughput sequencing techniques were employed to analyze the microbial communities. A total of 492,177 high-quality reads for bacterial communities and 1,001,229 optimized sequences for fungal communities were obtained. These sequences were assigned to 502 and 239 operational taxonomic units (OTUs) for bacteria and fungi, respectively. A higher diversity was recorded in AK samples than in SD and DL. Microbial community structure analysis showed higher diversity and significant fluctuation in specific taxa abundance in the metal-polluted samples exhibiting higher response of microbial flora to HM. In AK samples, bacterial genera such as Gordonia and Burkholderia-Caballeronia-Paraburkholderia were dominant, while in SD Pseudomonas and Streptomyces were dominant. Among the fungal taxa, Fusarium, Saccharomycopsis, and Lecanicillium were prevalent in HM-contaminated sites. Our finding revealed the influential effect of HM contaminants on reshaping the seed microbiome of the Zea mays, showing both the resilience of certain important microbial taxa as well the shifts in the diversity in the contaminated and pristine conditions. The knowledge will benefit to develop effective soil remediation, reclamation, and crop management techniques, and eventually assisting in the extenuation of metal pollution's adverse effects on plant health and agricultural productivity.

Turning Solid Waste into Catalysts: A Path for Environmental Solutions.

Waste, often overlooked, stands out as a prime source of valuable products, meeting the demand for natural resources. In the face of environmental challenges, this study explores the crucial role of waste-derived catalysts in sustainable practices, emphasizing the transformative potential of solid waste materials. Carbon-based catalysts sourced from agricultural, municipal, and industrial waste streams can be transformed into activated carbon, biochar, and hydrochar which are extensively used adsorbents. Furthermore, the paper also highlights the potential of transition metal-based catalysts derived from spent batteries, electronic waste, and industrial byproducts, showcasing their efficacy in environmental remediation processes. Calcium-based catalysts originating from food waste, including seashells, eggshells, bones, as well as industrial and construction waste also find an extensive application in biodiesel production, providing a comprehensive overview of their promising role in sustainable and eco-friendly practices. From mitigating pollutants to recovering valuable resources, waste-derived catalysts exhibit a versatile role in addressing waste management challenges and promoting resource sustainability. By transforming waste into valuable catalysts, this study champions a paradigm shift towards a more sustainable and resource-efficient future.

Rutin distribution in Tartary buckwheat: Identifying prime dietary sources through comparative analysis of post-processing treatments

Rutin is a crucial bioactive compound that determines the nutritional value of Tartary buckwheat (TB). However, the potential of utilizing TB as a dietary source of rutin for human consumption remains largely unexplored. This study aims to address these knowledge gaps by conducting a detailed analysis of rutin content distribution in TB tissues. Our findings revealed a significant variation in rutin content across different plant tissues. Notably, higher levels of rutin were found in embryos and cotyledons compared to other tissues, highlighting them as the primary sites of rutin accumulation in TB seeds and sprouts. Additional research on the processing of TB showed that sprouts and seeds retain high rutin levels even after boiling, steaming, deep-frying, stir-frying, and popping. Comparative analysis of different TB-derived products confirmed that cooked seeds and sprouts can serve as significant dietary sources of rutin. This study offers a foundational framework for the development of future dietary recommendations and applications of TB.

Revisiting the role of light signaling in plant responses to salt stress

Abstract As one of the grave environmental hazards, soil salinization seriously limits crop productivity, growth and development. When plants are exposed to salt stress, they suffer a sequence of damage mainly caused by osmotic stress, ion toxicity and subsequently oxidative stress. As sessile organisms, plants have developed many physiological and biochemical strategies to mitigate the impact of salt stress. These strategies include altering root development direction, shortening the life cycle, accelerating dormancy, closing stomata to reduce transpiration and decreasing biomass. Apart from being a prime energy source, light is an environmental signal, which profoundly influences plant growth and development and also participates in plants’ response to salt stress. This review summarizes the regulatory network of salt tolerance by light signals in plants, which is vital to further understanding plants’ adaptation to high salinity. In addition, the review highlights potential future uses of genetic engineering and light supplement technology by light-emitting diode (LED) to improve crop growth in saline-alkali environments in order to make full use of the vast saline land.

Perlindungan Hukum Terhadap Data Pribadi Nasabah Oleh Bank Dalam Transaksi Melalui Internet Banking

Technological advances have been able to give birth to services that facilitate daily activities such as the presence of internet banking services. However, there are still many problems related to the unprotection of customer personal data. The formulation of the problem from this study is how to legally protect the security of customer personal data by banks in internet banking services and how bank accountability in terms of personal data belonging to customers is not protected due to the use of internet banking services. The research method used in this thesis research is a normative type of legal research with a type of statutory and conceptual approach. The data sources used are prime, secondary, and tertiary data sources. The collection of legal materials is carried out through a library study. The results showed that the form of preventive legal protection was carried out by providing socialization through the platform to inform about the protection of customer personal data and the applicability of the ITE Law and the Telecommunications Law which provides a protection to prevent disputes against customers. The form of repressive legal protection is carried out through the existence of the Consumer Protection Law which is the basis for the fulfilment of consumption rights. The form of bank liability to customers in the event of a data leak is that the bank will provide compensation if it is proven that it is true that the data leak is not caused by the customer's negligence or mistake.

Speech Act Analysis: Pakistani Private Universities as a Case in Point

The marketisation of higher education has received mushrooming growth in not only Pakistan but all around the globe for the last few years. Most of Pakistani universities are modifying prospectuses’ discourse to market their image and establish credibility in the competitive academic environment under the influence of marketization. The present study aimed to analyse speech acts in the educational discourse which were manifested in the recognition and reputation of universities. In the current study, the researcher has used prospectus discourse as the prime source of data to evaluate its significance in an educational environment. This study has employed a qualitative exploratory paradigm to analyze the data collected from prospectuses of Pakistani private universities. In this context, the present study has explored variations of linguistic characteristics i.e. speech acts which have been embedded in the administrative discourse to represent universities in the Pakistani academic market. The current study has attempted to employ speech acts as interpretive tools to investigate how persuasive language is used in the academic discourse of Pakistani private universities. The findings have revealed that the text of academic discourse is aligned with the commoditized practices of marketisation in the current scenario prevailing in Pakistan. The present study has also highlighted the hidden ideological perspective incorporated and displayed through speech acts in the educational discourse of Pakistani private universities.

An essential role for the latero-medial secondary visual cortex in the acquisition and retention of visual perceptual learning in mice

Perceptual learning refers to any change in discrimination abilities as a result of practice, a fundamental process that improves the organism’s response to the external environment. Visual perceptual learning (vPL) is supposed to rely on functional rearrangements in brain circuity occurring at early stages of sensory processing, with a pivotal role for the primary visual cortex (V1). However, top-down inputs from higher-order visual areas (HVAs) have been suggested to play a key part in vPL, conveying information on attention, expectation and the precise nature of the perceptual task. A direct assessment of the possibility to modulate vPL by manipulating top-down activity in awake subjects is still missing. Here, we used a combination of chemogenetics, behavioral analysis and multichannel electrophysiological assessments to show a critical role in vPL acquisition and retention for neuronal activity in the latero-medial secondary visual cortex (LM), the prime source for top-down feedback projections reentering V1.

Characteristics and Source Apportionment of Volatile Organic Compounds in a Coastal Industrial Area: A Case Study in the Yangtze River Delta of China.

In recent years, the coastal area in East China has experienced elevated volatile organic compounds (VOCs) levels during specific periods. VOCs have become one of the major atmospheric pollutants in these areas. In this study, 64 compounds including alkanes, alkenes, halohydrocarbons, aromatics, and oxygenated VOCs (OVOCs) were obtained by the TO-15 method through a 12-month campaign in industrial, urban and suburban areas in the Yangtze River Delta of China. The overall trends of total VOC (TVOC) concentrations at eight sampling sites were as follows: winter > autumn > spring > summer. The proportion of VOC categories was various at industrial sites, while OVOCs and halohydrocarbons had high proportions at urban sites and suburban sites, respectively. Coating, vehicle emission, petrochemical source, industrial source, and gasoline volatilization were identified as the major VOC emission sources by the positive matrix factorization model. Petrochemical and coating sources were the prime VOC sources at industrial sites. Aromatics contributed the most ozone formation potential at industrial sites, while OVOCs provided the main contributions at both urban and suburban sites during four seasons. According to the health risk assessment, a high probability of non-carcinogenic risk existed at three industrial sites. Special attention should be given to certain VOCs, such as acrolein and 1,2-dibromoethane in industrial areas.

Performance enhancement of solar air heater with two-sided curvilinear transverse rib: Experimental and numerical investigation

Solar energy as prime energy source draws attention of world due to its availability and eco-friendliness. Low performance of solar air heater create curiosity for researchers to increase its performance. To enhance performance of solar air heater active and passive techniques used by researcher. Surface modification is one of the most prominent passive techniques to improve the performance. Present experimental and numerical investigation explore thermal characteristics of two-sided curvilinear rib roughened solar air heater. An indoor experiment was performed on two side curvilinear rib roughened absorber plate having constant heat flux of 1000 W/m2. Parallelly 2-dimensional numerical simulation was also performed to explore flow behavior and to complete investigation within optimum cost. ANSYS Fluent 2021.R was used for performing this simulation with K-ε RNG model with enhanced wall treatment. Velocity inlet and pressure outlet was selected as boundary condition. Main roughness and flow parameters were relative roughness height ( e/ D h = 0.21–0.042), relative roughness pitch ( p/ e = 7.14–35.71), and Reynolds number ( Re = 3800–18,000). Maximum value of Nusselt number improvement ratio and friction factor improvement ratio was 3.17 and 3.26 at roughness and flow parameter of ( e/ D h = 0.042, p/ e = 15, Re = 15,000) and ( e/ D h = 0.042, p/ e = 7.14, Re = 3800) respectively. Thermohydraulic performance parameter achieved its maximum value of 2.77 at e/ D h = 0.042, p/ e = 17.85, and Re = 18,000.

Safety assessment of rat embryonic fraction for in vivo regenerative therapy.

Regenerative therapy is considered a novel option for treating various diseases, whereas a developing embryo is a prime source of molecules that help repair diseased tissue and organs. Organoid culture studies also confirmed the inherent biological functions of several embryonic factors. However, the in vivo safety and efficacy of embryonic protein fraction (EPF) were not validated. In this study, we investigated the effectiveness of EPF on healthy adult rats. We obtained embryos from Sprague-Dawley (SD) female rats of E14, E16, and E19 embryonic days and collected protein lysate. This lysate was administered intravenously into adult SD rats on sequential days. We collected blood and performed hematological and biochemical parameters of rats that received EPF. C-reactive protein levels, interleukin-6, blood glucose levels, serum creatinine, blood urea, total leucocyte counts, and % of neutrophils and lymphocytes were comparable between rats receiving EPF and saline. Histological examination of rats' tissues administered with EPF is devoid of abnormalities. Our study revealed that intravenous administration of EPF to healthy adult rats showed that EPF is non-immunogenic, non-inflammatory, non-tumorigenic, and safe for in vivo applications. Our analysis suggests that EPF or its components could be recommended for validating its therapeutic abilities in organ regenerative therapy.

Air quality assessment of a mass deployment of microgrids

Microgrids are emerging to mitigate the degradation in grid resiliency and reliability resulting from an increasing frequency of grid outages. Because microgrids incorporate a local source of power generation, the production of electricity is shifting from a centralized to distributed topology, thereby installing power generation resources and the concomitant emissions into heavily populated urban air sheds and residential communities. In this paper, the air quality and public health impacts of a mass deployment of microgrids in an urban air shed are assessed. Candidates to become microgrids are identified for both the near- and long-term deployment, and two microgrid scenarios are considered, differing by the 24/7 prime source of power: (1) combustion gas turbine (CGT)-based microgrids and (2) zero-emission fuel cell (FC)-based microgrids complemented by solar PV and battery energy storage. Spatially and temporally resolved emissions from the microgrids are input to an air quality model and assessed for health impacts. The results show that (1) a mass deployment of CGT-based or FC-based microgrids in both the near- and long-term has a relatively small impact on air quality, (2) the health impacts are nonetheless significant for CGT-based microgrids due to the large and dense population of the area, and (3) disadvantaged communities are disproportionately impacted with the deployment of CTG-based microgrids. For example, near-term deployment of CGT-based microgrids results in an increase in the incidence of premature mortality(1 to 5 incidences per month) and an increase of $33 to $56 million per month in health costs. Deploying zero-emission FC-based microgrids mitigates the adverse health impact, prevents several incidences of premature mortality, and results in saving of ~$36M per month rather than a cost per month of ~$50M.

WITHDRAWN: Prospects of graphene quantum dots preparation using lignocellulosic wastes for application in photofermentative hydrogen production

Graphene quantum dots (GQDs) are a novel carbon nanomaterial from the graphene family due to their unique physicochemical properties and diverse range of applications. However, in terms of the sustainable utility of GQDs, their synthesis methods are the main roadblock because of their high production costs and the release of toxic byproducts during the production processes. Thus, the search for sustainable and economical fabrication methods for preparing GQDs is one of the most essential areas of research for their practical applications. In this context, lignocellulosic biomass (LCB) wastes are a prime choice for the fabrication of GQDs due to their high carbon and cellulose content, which are favorable for being employed as precursors and reducing agents Additionally, LCBs are a prime source of potential bioenergy production, which is currently a key research hotspot to combat environmental pollution, global warming, and energy crises. Therefore, the present review provides feasibility for sustainable and environmentally friendly fabrication of GQDs using LCB wastes for their possible utility in cellulosic biofuel production technology improvement. Furthermore, the prospective of using these GQDs as catalysts in bioenergy production for the development of low-cost biomass-based biofuel production technology has been discussed along with the existing limitations and their sustainable recommendation.

Knowledge on Uterine Prolapse among the Married Women in Banepa Municipality, Kavrepalanchowk

Background Uterine prolapse is a prevalent issue among women, particularly in low- and middle-income countries like Nepal, significantly impacting their quality of life. Despite its impact, there is a lack of comprehensive knowledge and awareness about this condition among the affected population, leading to delayed interventions and suboptimal healthcare-seeking behaviors. This study aimed to assess the knowledge about uterine prolapse among married women of reproductive age group in Banepa, Kavrepalanchowk.MethodsA cross-sectional study was conducted in Banepa Municipality, Nepal, from July to September 2019 after obtaining ethical approval from the Chitwan Medical College Institutional Review Committee. Face-to-face interviews with a total of 251 married women of the reproductive age group were done using a semi-structured questionnaire. Descriptive statistics, Chi-square tests, and multivariate logistic regression models were performed.ResultsThe study revealed that among all the respondents 86.3% had heard about uterine prolapse, with 42.5% demonstrating satisfactory knowledge. Religious affiliation, education, average monthly income of the family and prime source of knowledge on uterine prolapse were found to be significantly associated in bivariate logistic regression while taking them to the multivariate analysis education status (AOR=6.342, p=0.010) and religious affiliation (AOR=6.138, p=0.003) were found significantly influencing the knowledge level.Conclusions The study revealed significant knowledge gaps on uterine prolapse among married women in Banepa Municipality, Nepal, highlighting the imperative for targeted educational interventions. Socioeconomic factors and healthcare access influence awareness, emphasizing the need for culturally sensitive initiatives.

Dynamic learning of flue gas desulfurization process using deep LSTMs neural network

SO2 emissions are known to pose great harm to both human health and atmospheric air, and flue gas generated from coal-fueled power plant is the prime source of sulfur dioxide. For this reason, flue gas desulfurization (FGD) technology has found wide applications in most coal-fired power stations. Correctly describe the dynamic behavior of an FGD process is the precondition of controlling it effectively. However, FGD process modeling is by no means an easy task, as the underlying process dynamics are highly nonlinear in nature, meanwhile time-delay effect is significant therein. Long short-term memory (LSTM) network possesses remarkable long-term memory capability, hence it is anticipated to have a powerful identification capability. In this paper, the connection between deep learning and system identification is established, further a unidirectional/bidirectional LSTM deep network is designed and employed to identify a real FGD process. Simulation results clearly demonstrate the effectiveness of deep learning-based identification approach, and the superiority of deep LSTMs over other conventional identification models is also verified.

Surfactant-modified coconut coir powder (SMCCP) as a low-cost adsorbent for the treatment of dye-contaminated wastewater: parameters and adsorption mechanism.

The dye-contaminated wastewater discharged from various industries such as dye manufacturing, paint, textile, paper, and cosmetic is a prime source of surface water pollution having serious detrimental effects on both the environment and human beings. These hazardous dyes when exposed to water obstruct the penetration of sunlight into the water and thus restrain aquatic plants from generating photosynthetic compounds. Moreover, some dyes are potential cancer-causing and also negatively impact the human nervous and respiratory systems. In this current study, modification of coconut coir powder (CCP) was carried out through cationic surfactant treatment and was successively utilized as the adsorbent for decoloring anionic dye (acid blue 185 (AB 185)) containing waste stream. Further, a comparative investigation of the dye removal efficiency of raw CCP and surfactant-modified coconut coir powder (SMCCP) as the adsorbent was studied. On surfactant treatment, using a very minimal SMCCP dosage of 8.3g/L, a very high percentage dye removal of 98.4% is possible, whereas with raw CCP, even after using a higher dosage of 14g/L, only 70.1% dye removal can be achieved. Characterization of SMCCP adsorbent was done by Fourier transform infrared, thermogravimetric, X-ray, and scanning electron microscope analyses. Furthermore, the optimization of critical operating parameters was investigated for the effective adsorption of AB 185 dye in batch mode. The adsorption of AB 185 onto SMCCP was a thermodynamically spontaneous endothermic process, following the Langmuir isotherm and pseudo-second-order kinetic model. Moreover, regeneration of exhausted SMCCP by 0.1 (M) NaOH was achieved with a satisfactorily high recovery of 97% in the first cycle. Subsequently, SMCCP can be successfully reutilized for five consecutive cycles with a loss of 17.6% in the total adsorption capacity. With all such advantages, the present study delivers a new paradigm to utilize the novel adsorbent SMCCP as a promising eco-friendly adsorbent aided by its advantage of regeneration and reusability for the treatment of dye-contaminated wastewater.

The role of governance in the digital transformation of healthcare: Results of a survey in the WHO Europe Region

Optimal governance is among the key facilitators of the digital transformation of health systems intended to improve access to healthcare, quality, safety, and efficiency, and to attain universal health coverage. This paper highlights the findings of a survey assessing the status of governance of digital health in the WHO European Region.The 2022 survey is a continuation of the 2015 WHO Global Survey on eHealth. The survey focused on national digital health governance, monitoring and evaluation of digital health interventions, and funding and investment in digital health and was conducted through April to October 2022. All 53 Member States of the WHO European Region participated in the survey.The results showed that 83% of the Member States reported having a national digital health strategy in place, and 79% of the Member States reported having a health information system strategy. Most of the priorities of the national digital health strategies were devoted to increasing the accessibility, quality, safety, and efficiency of the health systems, strengthening health information systems, and improving information sharing and interoperability of data. Measures to ensure equity in access to digital healthcare services were directed towards improving broadband connectivity, information and communication technology, digital literacy, and digital health promotion. Oversight for the implementation and operation of the national digital health strategies are mostly delegated to government agencies. The prime source of funding for digital health programs was public funding, though a combination of funding sources was also noted. This analysis revealed increasing adoption of national digital health strategies for access to healthcare and creation of digital health agencies and funding programs for digital health.