The paper aims to make a comparative presentation of the latest information technologies used in managing complex projects, with specific reference to the applications, tools and integrated informatics systems for the management of project implemented in the business environment. There are considered, in particular: Parameters and key features of the most used project management solutions available on the market today; The continuous development of software and hardware infrastructure based on digital, media and communication technologies, which determines the performance of the computer systems used in project management; this involves the continuous adaptation of the applications, tools and systems used in project management to the new market demands, which determines project managers to update their knowledge in this area and increase their level of training; Possibilities to integrate the applications, instruments and dedicated project management informatics systems into the existing informatics systems and to adapt them to the specific conditions for specific complex business environment; Costs of implementing integrated informatics solutions for project management; Advantages and disadvantages of using project management solutions for businesses. The analysis of the integrated informatics solutions for project management is done by particular case studies covering the most popular project management integrated informatics systems (EPM - Enterprise Project Management) and project management dedicated modules from the most used type of integrated information systems (ERP - Enterprise Resource Planning).There are presented comparatively EPM systems used in Romania: Primavera P6 integrated in Charisma Enterprise ERP - offered by TotalSoft, Microsoft Project Management -Projects suite integrated into the ERP offered by iQuest, Apertix integrated into BPM Wave (Business Process Management Wave) ERP - offered by Edata, Spider provided by Spider Management Technologies Romania, the Project Management module included in Socrate Open Enterprise ERP offered by BitSoftware.