Primary Mucinous Cystadenoma Research Articles

Primary mucinous cystadenoma of the spermatic cord within the inguinal canal

We report a hitherto not documented case of primary mucinous cystadenoma arising in the spermatic cord within the right inguinal canal of a78-year-old man. The tumor was painless, hard and mobile. A computed tomography scan on the pelvis revealed an oval shaped, low attenuation mass, measuring 5.0x2.5x2.1 cm, that was present adjacent to the vas deferens. Grossly, the excised mass was multicystic mucinous tumor, filled with thick mucoid materials. Microscopically, the cystic wall was irregularly thickened. The cystic epithelium commonly showed short papillae lined by a single layer of columnar to cuboidal mucinous epithelial cells without significant stratification or cytologic atypia. Goblet cells were also frequently present. Immunohistochemically, the neoplastic cells showed positive reaction to carcinoembryonic antigen, cytokeratin 20, CDX2, epithelial membrane antigen, and CD15. However, they were negative for PAX8 and Wilms’ tumor 1 protein. Pathological diagnosis was a papillary mucinous cystadenoma of the spermatic cord. Although mucinous cystadenoma in this area is extremely rare, it is important that these lesions be recognized clinically and pathologically in order to avoid unnecessary radical surgery.Virtual slidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1720965948762004

A Rare Case of Primary Mucinous Cystadenoma of Spleen

Mucinous cystadenomas are relatively uncommon benign cystic tumors. Most of them are found in the ovary, pancreas, and appendix. Primary mucinous cystadenoma of spleen is extremely rare and only countable cases have been recorded. These are assumed to arise from heterotopic pancreatic tissue or invaginated spleenic capsular mesothelium. We present a rare case of primary mucinous cystadenoma of spleen without pancreatic tissue in it. Exact tissue of origin could not be determined.KeywordsCystadenoma; Splenic cyst; Pseudomyxoma peritonei

Rare Cystic Mucinous Cystadenoma Presenting as a Scrotal Mass

Recently, our institution reported on a rare primary retroperitoneal mucinous cystadenocarcinoma which was only the second type of this kind of tumor ever reported in a male patient. To our knowledge, we report the first male case of a primary mucinous cystadenoma presenting as an enlarging scrotal mass. These lesions are extremely rare and represent only 0.3% of all appendiceal specimens. Because the number of these tumors remains limited, proven treatment regimens and the necessary follow-up have yet to be elucidated. We hope to provide further insight in the monitoring and treatment of these tumors.

The First Case of Primary Retroperitoneal Mucinous Cystadenoma in Korea: A Case Report

Primary mucinous cystic cystadenomas of the retroperitoneum are very rarely encountered, and there have been only about 30 cases reported in the literature. The histogenesis of primary mucinous cystadenomas is unclear. Most authors suggested that it develops through mucinous metaplasia in a pre-existing mesothelium-lined cyst. Complete surgical excision is the only treatment and it is required for the final diagnosis and cure. We present here a case report of a 38-year-old Korean woman with primary retroperitoneal cystadenoma. It was a thin-walled, multilocular cyst with a dominant loculus that measured 10.0×7.5×5.5 cm3 in size, and to the best of our knowledge, this is the first such case to be reported in in Korea.

Primary Mucinous Cystadenoma Arising from Behind the Posterior Peritoneum of the Descending Colon in a Child: A Case Report

This is the first report of a primary mucinous cystadenoma (MCA) arising from behind the posterior peritoneum of the descending colon in a paediatric patient. A large intra-abdominal cystic lesion was found incidentally during renal ultrasonography in a 14-year-old girl. Imaging studies showed a 13 x 9 x 15 cm homogeneous cystic lesion with mild contrast enhancement of the wall. The cyst appeared to originate from the retroperitoneum, but was separated from the left kidney, ovary, and pancreas. At laparotomy, there was a cyst behind the posterior peritoneum of the descending colon. The cyst was successfully excised, and histopathology showed MCA. Although primary MCA in the retroperitoneum is extremely rare in children, it should be considered in the differential diagnosis of an intra-abdominal cyst, since it needs to be excised to eliminate the risk of infection, recurrence, and malignancy.

A mucinous tumor of the mesocolon with features of borderline malignancy

Primary mucinous cystadenoma of the mesocolon is a rare tumor with an uncertain histogenesis. A 38-year-old woman was diagnosed with a 17-cm cystic lesion in the left abdomen, identified as a mucinous cystadenoma of the mesocolon. This type of tumor appears rarely in extraovarian sites. We believe that metaplasia, either celomic or mucinous, is the most likely pathogenic mechanism. On rare occasions, a borderline or invasive component may be present.

Measurement of CA125, carcinoembryonic antigen, and alpha‐fetoprotein in ovarian cyst fluid: Diagnostic adjunct to cytology

This study used CA125, carcinoembryonic antigen (CEA), and alpha-fetoprotein (AFP) to classify ovarian cysts by measuring the levels of the three antigens; this information was useful when fluid obtained through laparoscopic puncture of ovarian cysts was submitted for cytologic examination from patients for whom tissue was unavailable for classification. We studied 136 consecutive cyst fluids (108 benign, 28 malignant) and correlated the findings with the tissue diagnosis. All three antigens were very low (CEA, less than 0.5 ng/ml; CA125, 55-2,143 mu/ml; and AFP, less than 4.8 ng/ml) in follicular and lutein cysts. Markedly elevated CA125 (296-1,950,000 mu/ml) and low CEA (0.5-220 ng/ml) and AFP (less than 4.8 ng/ml) levels were seen in patients with serous neoplasms, both benign and malignant. Elevated CEA (greater than 600 ng/ml) and CA125 (56-65,330 mu/ml) levels were seen in primary mucinous cystadenoma and cystadenocarcinoma. Two patients with colonic carcinoma metastatic to the ovary had an elevated CEA (greater than 600 ng/ml) and a normal CA125. Only one patient, with a malignant teratoma, had an elevated AFP. The adjunctive use of CEA and CA125 is recommended for the classification of ovarian cysts.