Purpose To evaluate the effect of limbal relaxing incisions (LRIs) in the treatment of primary mixed astigmatism and mixed astigmatism after cataract surgery. Setting Department of Ophthalmology, Inönü University, Malatya, Turkey. Methods Limbal relaxing incisions were performed to correct astigmatism in 37 eyes of 26 patients with mixed astigmatism. Twenty-four eyes had primary astigmatism, and 13 eyes had astigmatism after cataract surgery. The length, number, and depth of the incisions were determined using the Gills and Gayton nomogram. The manifest refractive astigmatism was measured preoperatively and 1 day, 1 week, and 1, 3, 6, and 12 months postoperatively. Surgically induced astigmatism using the vector method, preoperative and postoperative uncorrected visual acuity (UCVA), and best spectacle-corrected visual acuity (BSCVA) were evaluated. Follow-up was at least 6 months in all cases. Results The mean preoperative and postoperative refractive astigmatism was 3.31 diopters (D) ± 1.50 (SD) and 1.59 ± 1.28 D, respectively ( P < .001). The mean absolute change in refractive astigmatism was 1.72 ± 0.81 D. No patient lost lines of UCVA or BSCVA. The safety index was 1.21 and the efficacy index, 0.88. The mean preoperative and postoperative UCVA was 0.29 ± 0.22 and 0.54 ± 0.31, respectively ( P = .0001) and the mean BSCVA, 0.61 ± 0.30 and 0.74 ± 0.30, respectively ( P = .0001). The mean vectorial magnitude was 2.32 ± 1.36 D at the last follow-up. There were no serious postoperative complications. Conclusion Limbal relaxing incisions are a simple, safe, and effective method to correct primary mixed astigmatism and mixed astigmatism after cataract surgery.