Event Abstract Back to Event Does Sequence Foreknowledge or Concurrent Task Affect First-Impression Bias in Mismatch Negativity? Jade D. Frost1*, Kelly McDonnell1, Alexander L. Provost1 and Juanita Todd1 1 University of Newcastle, Psychology, Australia The auditory system accumulates evidence about regularity across varying timescales to model predictions about subsequent sound. The evoked-potential component mismatch-negativity (MMN) is elicited upon detection of any pattern-deviation and reflects a ‘prediction-error’. MMN amplitude is proportional to ‘confidence’ in underlying predictions; MMN is largest when patterns are very stable. Using a ‘multi-timescale’ paradigm, we have consistently demonstrated that MMN amplitude does not faithfully reflect sequence stability but instead succumbs to a ‘first-impression bias’ that is coupled to initial tone roles. In the paradigm participants hear two-tone sequences in which tones alternate roles of standard (p = .875) and deviant (p = .125). In stable sequences, roles alternate every 2.4min (480 tones per block; 420-standard, 60-deviant). In unstable sequences, roles alternate every 0.8min (160 tones per block; 140-standard, 20-deviant). The first-impression bias refers to the observation that only MMN in the first stimulus configuration show the expected stability-modulation (stable>unstable). To date all multi-timescale paradigms have been presented while participants have no knowledge of the sequence structure and watch a silent movie. In this study, we attempted to disrupt the bias by modifying engagement of higher-level brain areas in monitoring longer-term patterns thought to underpin it. The primacy bias pattern did not occur when participants performed a demanding concurrent N-Back task (study-1) or were first informed about the sequence structure (study-2) before watching a silent movie. Our results are interpreted as evidence that engagement of higher-order brain areas is required to make predictions about patterning over longer timescales. References Friston, K. (2005). A theory of cortical responses. Philos Trans R Soc Lond B Biol Sci, 360, 815-836. Owen, A. M., McMillan, K. M., Laird, A. R., & Bullmore, E. (2005). N-back working memory paradigm: A meta-analysis of normative functional neuroimaging studies.Human Brain Mapping, 25, 46-59. Mullens, D., Woodley, J., Whitson, L., Provost, A., Heathcote, A., Winkler, I., & Todd, J. (2014). Altering the primacy bias—How does a prior task affect mismatch negativity? Psychophysiology, 51, 437-445. Todd, J., Provost, A., Cooper, G. (2011). Lasting first impressions: A conservative bias in automatic filters of the acoustic environment. Neuropsychologia, 49, 3399-3405. Todd, J., Heathcote, A., Mullens, D., Whitson, L. R., Provost, A., & Winkler, I. (2013). What controls gain in gain control? Mismatch negativity (MMN), priors and system biases. Brain topography, 1-12. Winkler, I., Karmos, G., & Näätänen, R. (1996). Adaptive modeling of the unattended acoustic environment reflected in the mismatch negativity event-related potential. Brain research, 742, 239-252. Keywords: context, Bias, First-impressions, auditory, Mismatch Negativity., ERP/EEG, predictive coding, salience coding, Prediction error Conference: ASP2015 - 25th Annual Conference of the Australasian Society for Psychophysiology, Sydney, Australia, 2 Dec - 4 Dec, 2015. Presentation Type: Poster Presentation Topic: Psychophysiology Citation: Frost JD, McDonnell K, Provost AL and Todd J (2015). Does Sequence Foreknowledge or Concurrent Task Affect First-Impression Bias in Mismatch Negativity?. Conference Abstract: ASP2015 - 25th Annual Conference of the Australasian Society for Psychophysiology. doi: 10.3389/conf.fnhum.2015.219.00044 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 28 Sep 2015; Published Online: 30 Nov 2015. * Correspondence: Miss. Jade D Frost, University of Newcastle, Psychology, Newcastle, New South Wales, 2300, Australia, jade.frost@uon.edu.au Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Jade D Frost Kelly McDonnell Alexander L Provost Juanita Todd Google Jade D Frost Kelly McDonnell Alexander L Provost Juanita Todd Google Scholar Jade D Frost Kelly McDonnell Alexander L Provost Juanita Todd PubMed Jade D Frost Kelly McDonnell Alexander L Provost Juanita Todd Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.