1.1. A brief review of principles gleaned from the literature is presented.2.2. All the cases in which sulfanilamide powder was used at operation at the Woman's Hospital during 1941 are reviewed, and only two complications due to the use of the drug were noted. One was a severe cyanosis, and the other was hepatitis, which ended in death of patient, but other factors than the sulfanilamide were operating in this case, and only 6 Gm. were used.3.3. Prevention of abscesses at the upper end of the vagina and prevention of peritonitis are the two clear-cut objectives to be striven for in the use of the powder in complete abdominal and in vaginal hysterectomies. In our short series, progress was made toward both of these. In cases with infection, prevention of peritonitis is more difficult to evaluate, and abscess formation harder to control, due to the variability in degree and virulence of infection and amount of spill.4.4. Sulfanilamide did not prevent urinary, respiratory, nor circulatory complications, nor did it rescue moribund patients. Its use cannot obviate the need for good judgment and early treatment.
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