Prevention Of Iodine Deficiency Research Articles

Trajectories of Maternal Urinary Iodine Concentration Are Associated With Gestational Diabetes Mellitus.

The relationship between iodine status and gestational diabetes mellitus (GDM) is inconclusive. This study aimed to explore the trajectories of urinary iodine concentrations (UIC) in pregnant women before GDM diagnosis and to assess the associations between maternal UIC trajectories and the risk of developing GDM. A prospective cohort study was conducted in China. Data from 1076 pregnant women who were recruited between August 2019 and December 2021 were analyzed. GDM screening was performed at the 28th week of pregnancy. Arsenic and cerium catalysis spectrophotometry was used to measure UIC. The latent class model was used to identify distinct UIC trajectories in pregnant women, using multiple urine specimens. We evaluated the association of UIC trajectories with the risk of GDM by logistic regression analysis. Three maternal UIC trajectories were identified: (1) high-stable trajectory (72.12%), (2) high-decreasing trajectory (3.07%), and (3) low-stable trajectory (24.81%). Compared with the pregnant women in high-stable trajectory group, women in the low-stable UIC trajectory group showed an increased risk of GDM before adjustment of covariates (OR: 1.58, 95% CI: 1.08-2.27). After adjusting for different covariates, a statistically significant association was observed only between low-stable trajectory trajectories and GDM. This study highlights a relationship between UIC and the risk of GDM. To better prevent iodine deficiency and GDM, persistent sufficient iodine status from pregnancy to delivery, should be emphasized.

Quantitative determination of iodine content in iodized table salt marketed in Jordan as an indicator of compliance with national salt iodization standards: A cross-sectional study

Iodine deficiency (ID) is a significant global public health issue, particularly affecting low-income countries. The iodization of salt is a widely adopted method to prevent iodine deficiency. This study aimed to assess the iodine content of iodized salt at the market level in various cities within the Hashemite Kingdom of Jordan (HKJ). We collected 152 salt samples from 24 different brands across three cities in Jordan: Amman, Zarqa, and Mafraq. The analysis was conducted using a titration method. The mean iodine content in salt samples varied by city, with values of 5.45 ppm in Mafraq, 10.33 ppm in Amman, and 13.22 ppm in Zarqa, ranging from 0 to 36 ppm. Significant differences in iodine concentration were observed within the same city across different brands (P ≤ 0.05). Additionally, variations were noted in iodine content for samples from the same brand collected in different cities, and even among samples from the same brand at the same location. Of the 152 samples evaluated, an average of 76.5% had iodine levels below the 15 ppm recommended by UNICEF. There was considerable variation in mean iodine content among brands, cities, and even within samples of the same brand. This indicates that the salt iodization process requires ongoing monitoring, and the government should enhance efforts to oversee the iodization process and improve the accessibility and utilization of iodized salt.

Обогащение кисломолочных продуктов йодом в целях профилактики и лечения йододефицита

To provide the population of Kyrgyzstan with iodine in the amount necessary for physiological needs, salt enriched with this microelement is used, but the amount of iodine in it is very difficult to control. A good alternative to iodized salt can be fermented milk products enriched with walnut leaf extract, rich in iodine. Walnut is a local plant in Kyrgyzstan; it grows freely in all regions of Kyrgyzstan, but its plant raw materials are not used in food technology. This paper discusses the technology for preparing whipped curd dessert with the addition of walnut leaf extract. Adding an extract from dried and crushed walnut leaves to the recipe for curd dessert does not impair their organoleptic properties, and due to the high content of organic iodine, this product can be used to enrich the diet and prevent iodine deficiency.

ПОКАЗАТЕЛИ КАЧЕСТВА МОЛОКА И МОЛОЧНОЙ ПРОДУКТИВНОСТИ ПРИ ИСПОЛЬЗОВАНИИ ПРЕПАРАТА «ЙОДИНОЛ-ЯНТАРНЫЙ» В РАЦИОНЕ ЛАКТИРУЮЩИХ КОЗОМАТОК НУБИЙСКОЙ МЯСО-МОЛОЧНОЙ ПОРОДЫ

Proper nutrition is a prerequisite for normal physiological and mental development, as well as strengthening immunity to various adverse environmental factors. Goat milk products are especially relevant in baby food due to their unique properties. The reduced casein content in the fractional composition of proteins makes the products hypoallergenic, and the predominance of casein contributes to the rapid formation of a fine clot in the child's stomach. A high naive degree of fat dispersion facilitates and improves its assimilation, and also contributes to the assimilation of a large amount of polyunsaturated fatty acids that ensure the normal development and formation of the child's body. In addition, goat's milk contains a large amount of vitamins: A, C, B, PP, as well as trace elements: calcium, phosphorus, magnesium, cobalt. Providing children with high-quality balanced food is an important state task, the fulfillment of which is the key to the health of the nation. Since most regions of Russia are iodine deficient, they need the trace element iodine for life, which is why it is necessary to adjust the mineral composition of goat's milk. For the animals themselves, this is also relevant for the treatment and prevention of iodine deficiency. The influence of an energy-metabolic preparation based on iodine and succinic acid on the quality indicators of milk and milk productivity of lactating goats is considered. Literature data indicate an increase in the therapeutic effect when succinic acid is added to the active substance. In nature, there is a direct relationship between the iodine content in soil, water, plants and in the animal body. With insufficient intake of iodine with feed and water, the productivity, reproductive qualities, and genetic potential of animals decrease. Therefore, an urgent problem is to find ways to replenish iodine deficiency in the body of farm animals. In this regard, studies were conducted on the quality of milk of lactating goats of the Nubian meat and dairy breed when they were injected with a new drug "Iodinol-Yantarny". The effective effect of this drug on milk quality indicators in dairy goat breeding has been proven.

Microfluidic Paper-Based Device Incorporated with Silica Nanoparticles for Iodide Quantification in Marine Source Dietary Supplements.

Iodine is an essential micronutrient for humans due to its fundamental role in the biosynthesis of thyroid hormones. As a key parameter to assess health conditions, iodine intake needs to be monitored to ascertain and prevent iodine deficiency. Iodine is available from various food sources (such as seaweed, fish, and seafood, among others) and dietary supplements (multivitamins or mineral supplements). In this work, a microfluidic paper-based analytical device (μPAD) to quantify iodide in seaweed and dietary supplements is described. The developed μPAD is a small microfluidic device that emerges as quite relevant in terms of its analytical capacity. The quantification of iodide is based on the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) by hydrogen peroxide in the presence of iodine, which acts as the catalyst to produce the blue form of TMB. Additionally, powder silica was used to intensify and uniformize the colour of the obtained product. Following optimization, the developed μPAD enabled iodide quantification within the range of 10-100 µM, with a detection limit of 3 µM, and was successfully applied to seaweeds and dietary supplements. The device represents a valuable tool for point-of-care analysis, can be used by untrained personnel at home, and is easily disposable, low-cost, and user-friendly.

Structural Characterization of Salts Using X-ray Fluorescence Technique

This study investigates the structure of 21 table salts that were collected from different local markets in the Kurdistan region of Iraq. The major trace elements and iodine concentrations in tablesalt are analyzed through the X-ray fluorescence (XRF) technique and the titration method, respectively. The study shows that using XRF spectral analysis, the collected table salt samples are rich in chlorine, sodium, and contain a lower percentage of bromine, strontium, tin, tellurium, and iodine. Moreover, these samples have a high percentage of sulfur and sirconium, where the molybdenum is >0.2%. Other elements such as zinc and copper are essential and found in low concentrations <0.0086% and 0.001%. Iodine is a trace element that is necessary nutrients for human life, and it is naturally present in some foods. Iodine deficiency is brought on by a lack of iodine consumption. Iodized salt is highly recommended as a source of iodine to prevent iodine deficiency disease. Iodine is added to table salt in two different ways, either through iodate or through iodine. The results show that only 25% of the salt samples have an adequate level of iodine, while the other samples have low or no iodine content. According to the World Health Organization, quality of salt depends on iodine concentration and other trace elements, which are necessary for human health.

Исследование влияния новой кормовой добавки «Протойодиум» на биохимический состав говядины, обогащенной йодом

Purpose. To study the effect of the new feed additive "Protojodium" on the chemical biocomposition of semi-finished beef enriched with iodine. Materials and Methods. The object of the research were Kazakh White-headed bulls, which were fattened with the help of a new feed additive "Protojodium", based on organic iodine. The biochemical composition of the resulting beef and the residual content of organic iodine in the raw materials were studied in the complex analytical laboratory of VRIMMP (Volgograd, Russia) using modern equipment and according to generally accepted methods: GOST 23042-2015, GOST 25011-2017, GOST R 31727 -2012, GOST R 70149-2022, GOST 23041-2015, GOST 26185-84). Results. As a result of the experiment, it was revealed that the raw materials obtained from the experimental group had a higher iodine content – by 48.5 micrograms or 31.05% compared with the control group. In turn, its biochemical composition was also significantly better, namely: superiority was revealed in the content of dry matter (by 1.87%), protein (by 0.51), ash (by 0.13%), tryptophan (by 12.59 mg), oxyproline (by 0.84 mg), protein quality indicator (by 0.11). And the fat content in raw materials obtained from cattle in the control group was 0.51% higher than in the experimental group. This was achieved through the use of a new feed additive “Protojodium” based on organic iodine in the feed diet of bull calves. Conclusion. The use of a new feed additive, the composition of which is based on organic iodine, has a positive effect on the biochemical composition of the resulting beef, and also effects the prevention of iodine deficiency in the population of the Russian Federation.

IN MEMORY OF PROFESSOR YAREMA TOMASHEVSKYI – SCIENTIST, DOCTOR AND TEACHER

We are deeply saddened to inform that on August 12, Yarema Illich Tomashevskyi, a distinguished professor of the Danylo Halytsky Lviv National Medical University, passed away at the age of 94.
 Professor Tomashevskyi was born on December 3, 1929, in the village of Stetseva in Pokuttia area. In 1953, he graduated with honors from Lviv Medical Institute and then studied in the clinical residency program for internal medicine from 1953 to 1955. In the following three years, he chaired the therapeutic departments of Kamianka-Buzka District Hospital and the 4th Hospital in Lviv. In 1958, he commenced employment as an assistant at Lviv Medical Institute and was subsequently promoted to Associate Professor of therapeutic departments. He started and chaired the Department of Endocrinology and Clinical Pharmacology, where he worked for 44 years, from 1978 to 2022. Yarema Illich created and developed the Lviv endocrinological school, the regional endocrinological dispensary, and headed the regional association of endocrinologists. He was a member of the Ukrainian Scientific Society of Endocrinologists.
 Professor Tomashevskyi’s scientific and research endeavors are centered around the issues of cardiology, rheumatology, gastroenterology, balneotherapy, clinical vitaminology, and endocrinology. He deemed the prevention of diseases to be of paramount significance. He founded the Academy of Preventive Medicine at the Shevchenko Scientific Society. He has worked on programs aimed at preventing iodine deficiency disorders and early diagnosis of diabetes, which he diligently implemented in practice. Professor Tomashevskyi is the author and co-author of over 350 publications, including seven monographs and textbooks and many methodological recommendations. Under his leadership, two doctoral and 15 candidate theses were successfully defended.
 The professor’s professional activities included membership in the Ukrainian Medical Association, the European Association for the Study of Diabetes, and editorial boards of the journals “Endocrinology” and “International Endocrinology Journal.” He also contributed to the compilation of scientific works “The Phenomenon of Human. Healthy lifestyle,” “Medical Collection of The Shevchenko Scientific Society.” He was a full member of the Shevchenko Scientific Society and headed the Medical Commission of the SSS for several years. He was respected and known in the medical scientific community of Ukraine. In 1985, Yarema Illich was awarded the badge “Excellence in Healthcare.”
 Professor Yarema Tomashevskyi was an excellent teacher and lecturer, a highly qualified doctor who was loved and respected by students, colleagues, and patients. He was a respected citizen. The professor led a respectable life full of tireless work and care. His favorite sayings from the ancient sacraments, which he steadfastly adhered to, were: “Rush to do good, as human life is fleeting; do everything in moderation; and never express anger.” He was always cheerful, smiling, and friendly.
 Eternal and bright be his memory!
 
 Chairman of the Medical Commission
 of Shevchenko Scientific Society,
 Doctor of Medicine, Professor Valentyna Chopyak

Разработка варено-копченых колбасных изделий с йодосодержащими компонентами

Purpose. Development and production of boiled-smoked sausages enriched with iodine. Materials and Мethods. The production of experimental boiled-smoked sausage products was carried out in accordance with GOST 55455-2013 using classical technology using crushed seaweed of the Laminaria family in the recipe. The samples were produced on the territory of the experimental workshop of the Sausage Shop “Technolog” (Volga State Technical University, Department of Food Production Technology). The determination of organoleptic and physicochemical parameters was carried out in accordance with generally accepted standards in the food industry on the territory of the VRIMMP (complex analytical laboratory CALab). Results. The main goal of the study was achieved – to obtain a product containing a high content of iodine, the regular use of which will reduce the risk of iodine deficiency. In terms of organoleptic indicators, the test sample with the addition of kelp did not lag behind the control sample. The addition of seaweed from the Laminaria family did not have a negative effect on the content of toxic substances. It has been experimentally proven that 100 g of sausage containing kelp contains 96 mcg of iodine. It is known that the daily intake of the trace element iodine is 150 mcg. This makes the food products under study indispensable for the reduction and prevention of iodine deficiency. Conclusion. The presented sausage products, enriched with iodine, can serve as a prevention of iodine deficiency in problem regions, including the Volgograd region.

The content of microelements in fruits of the oriental persimmon (Diospyros kaki) and its dietary role in remedying micronutrient deficiency in the region

The relevance of the problem under study lies in the need to develop innovative approaches to the introduction of fruit crops into the diet to avoid the loss of nutrients and thus help prevent micronutrient deficiency in the human body. In this regard, the purpose of this article is to study the content of biologically active substances in the products of promising persimmon varieties and their effect on the normal functioning of the thyroid gland. The following results were obtained during the study: soil and climatic conditions affecting the nutritional value of the agricultural product were presented. It was established that Shaki-Zagatala economic region is an iodine deficiency endemic area and belongs to the zone of moderate iodine (I) deficiency. The quantity of macro- and microelements in fruits of 20 varieties of Oriental persimmon (Diospyros kaki) bred by folk selection growing in Shaki-Zagatala economic region was studied and compared by regions; the use of persimmon plants in the food industry as a way of increasing the amount of iodine in the human body was substantiated. It has been proved that in order to eliminate iodine deficiency, it is advantageous to eat more food enriched with iodine from fruits of the Oriental persimmon (D. kaki), which is rich in microelements. The role of awareness – raising activities among the population regarding health disorders associated with iodine deficiency was revealed. The practical value of the article materials consists in obtaining detailed information about biochemical composition of Oriental persimmon fruit (D. kaki) for the purpose of iodine deficiency prevention. The technologies of processing and storage of the product in fresh and processed form to preserve the useful properties of persimmon have been proposed in order to increase the profitability of production and increase the level of sales of products in the Shaki-Zagatala economic region of Azerbaijan.

The efficacy of iodinated ethyl esters of safflower seed oil (Carthamus tinctorius L.) in the control of iodine deficiency in sheep

Iodine is an essential component of the thyroid gland hormones (T3 and T4), necessary for mammalian life. Iodine deficiency leads to inadequate thyroid hormone production, and all the consequences of iodine deficiency stem from the associated hypothyroidism. Iodized oil is made by treating a fatty vegetable oil with iodine or hydriodic acid and is an effective long-term means of iodine supplementation. The type and fatty acids profile in the parent oil, as well as the way iodine is trapped, affect the physicochemical properties and effectiveness of the product. This research was conducted to study the effect of iodinated safflower oil on preventing iodine deficiency disorders (IDD) in livestock, compared with a commercial iodine supplement. Iodinated fatty acid ethyl esters prepared from safflower seed oil (IFAEESSO). Thirty Farahani ewes with a history of iodine deficiency were divided into three groups, including control and two treatment groups. The treatment groups received 390 mg of iodine by an intramuscular injection of 1.26 ml of IFAEESSO (n = 10) or 1.5 ml of Depodine® (n = 10), respectively. Serum iodine, thyrotropin stimulating hormone (TSH), T3 and T4 concentrations were assayed at baseline and every 30-day intervals over six months period. Iodine supplementation resulted in a significant increase in serum inorganic iodine over five months with Depodine and IFAEESSO (P < 0.01). Serum T3 and T4 concentrations also increased in treatment groups (P < 0.01), while the concentration of TSH didn’t change. The mean T4 and T3 concentrations were 3.16 μg /dl and 53.89 ng /dl in the control group, which increased to 3.50 μg /dl and 58.88 ng/dl for Depodine and 3.88 μg /dl and 63.55 ng/dl for IFAEESSO, respectively. The serum inorganic iodine and thyroid hormone concentrations were significantly higher in the IFAEESSO group than in the Depodine group (P < 0.01). IFAEESSO is an effective supplement against IDD and more efficient than that of Depodine to increase serum iodine concentration, and thyroid hormone production.

Association study of urinary iodine concentrations and coronary artery disease among adults in the USA: National Health and Nutrition Examination Survey 2003-2018.

Iodine is a vital trace element in the human body and is associated with several important coronary artery disease (CAD) risk factors. We aimed to explore the correlation between urinary iodine concentration (UIC) and CAD. Data from 15793 US adults in the National Health and Nutrition Examination Survey (2003-2018) were analysed. We conducted multivariable logistic regression models and fitted smoothing curves to study the correlation between UIC and CAD. Furthermore, we performed subgroup analysis to investigate possible effect modifiers between them. We found a J-shaped association between UIC and CAD, with an inflection point at Lg UIC = 2·65 μg/l. This result indicated a neutral association (OR 0·89; 95 % CI 0·68, 1·16) between UIC and CAD as Lg UIC < 2·65 μg/l, but the per natural Lg [UIC] increment was OR 2·29; 95 % CI 1·53, 3·43 as Lg UIC ≥ 2·65 μg/l. An interaction between diabetes and UIC might exist. The increase in UIC results in an increase in CAD prevalence (OR 1·84, 95 % CI 1·32, 2·58) in diabetes but results in little to no difference in non-diabetes (OR 0·98, 95 % CI 0·77, 1·25). The J-shaped correlation between UIC and CAD and the interaction between diabetes and UIC should be confirmed in a prospective study with a series of UIC measurements. If excessive iodine precedes CAD, then this new finding could guide clinical practice and prevent iodine deficiency from being overcorrected.

Irina Petrovna Koryukina – a physician, teacher, scientist, talented organizer: to the 70-th anniversary of her birth (1953–2020)

Koryukina Irina Petrovna was a doctor, teacher, Honored Scientist of the Russian Federation and a talented leader. She was born in the family of a doctor. Her childhood, youth and professional activity are connected with our city Perm. Having graduated from the Medical Faculty of Perm State Medical Institute (now Perm State Medical University) with honors degree in 1976, she continued her training in the residency (19761978), and then in the postgraduate courses (19781981) at the Department of the Faculty of Pediatrics. Afterwards, she became the assistant of the department (1981), defended her Candidate's thesis (1982). During the period of 1985-1992, she was an Associate Professor, and since 1992 the Head of the Department of Pediatrics of the Physicians Advanced Training Faculty. In 1993, Irina Petrovna received the title of professor. From 2002 to 2005, she was Deputy Rector for Academic Activity. From 2005 to 2020, she was the Rector of Perm State Medical University. Irina Petrovna started her scientific work studying the problem of treatment and prevention of acute stenotic laryngotracheites in children, then she was engaged in the problem of diagnostics and prevention of iodine deficiency in Perm Region. Later, she conducted research on the prevention of allergic diseases, minimally invasive methods of bronchial asthma diagnostics, and improvement of regional outpatient care. Irina Petrovna loved her work and was ready to devote all her free time to it. Her professional activity resulted in more than 900 scientific papers published; she prepared 59 Candidates of Medical Sciences and 19 Doctors of Medical Sciences. Under a wise leadership of Irina Petrovna, the collective of Perm State Medical University was twice acknowledged by the President of the Russian Federation (2007, 2017).

Iodine supplementation for preventing iodine deficiency disorders in children and adolescents

Iodine supplementation for preventing iodine deficiency disorders in children and adolescents

Iodine Security of the Population: A Modern View of the Problem

Background. Iodine is one of the most important trace elements, without which the normal functioning of our body is impossible, and regular intake of iodine with food is of great importance for maintaining our health. To date, it has been proven that iodine deficiency can have serious consequences for human health at any age, but it is most dangerous for pregnant women, given its effect on fetal development and for children of the first years of life. The article presents up-to-date information on the prevalence of iodine deficiency and iodine deficiency diseases in the territory of the Russian Federation. Purpose. Based on the study of the results of a number of clinical studies, this paper is to determine the prevalence of iodine deficiency in the territory of the Russian Federation, modern methods of its diagnosis and impact on human health, as well as to consider possible ways to correct this condition. Materials and Methods . On the basis of the analysis of the data of modern scientific literature on the prevalence and modern methods of diagnosis of iodine deficiency, and its impact on human health modern methods of determining the iodine security of the population are considered, possible ways to prevent iodine deficiency are studied. Results. The paper presents up-to-date information on the prevalence of iodine deficiency and iodine deficiency diseases in the Russian Federation. Modern methods of determining the iodine security of the population are considered. The greatest attention is paid to the consideration of the method of mass prevention of iodine deficiency using iodized salt.

Salt-Containing Recipes in Popular Magazines with the Highest Circulation in the United States Do Not Specify Iodized Salt in the Ingredient List

Iodine deficiency is a public health problem in the US, with the iodine status of women of reproductive age decreasing in recent years. This may be attributable to voluntary salt iodization in the US. Magazines, a common source of recipes and nutritional information, may influence salt use and iodine intake. The aim of this study is to assess whether the magazines with the highest circulation in the US include recipes that contain salt and, if so, whether they specify "iodized salt" in the recipes. Recipes in eight of the top ten magazines by circulation in the US were examined. Standardized information was collected on the presence and type of salt in recipes in the last 12 issues reviewed per magazine. About 73% of the 102 issues reviewed contained recipes. A total of 1026 recipes were surveyed for salt; 48% of the recipes listed salt as an ingredient. None of the 493 recipes containing salt specified iodized salt as the type of salt to be used. About half of the recipes in the last 12 issues of popular magazines published in the US included salt in the ingredient list; however, none recommend the use of iodized salt. There is potential for editorial changes among magazines to call for iodized salt in recipes, which may further prevent iodine deficiency in the US.

ATA Centennial Interview Series: The Prevention of Iodine Deficiency—A History

ATA Centennial Interview Series: The Prevention of Iodine Deficiency—A History

Iodine Deficiency and Iodine Prophylaxis: An Overview and Update.

The thyroid gland requires iodine to synthesize thyroid hormones, and iodine deficiency results in the inadequate production of thyroxine and related thyroid, metabolic, developmental, and reproductive disorders. Iodine requirements are higher in infants, children, and during pregnancy and lactation than in adult men and non-pregnant women. Iodine is available in a wide range of foods and water and is susceptible to almost complete gastric and duodenal absorption as an iodide ion. A healthy diet usually provides a daily iodine consumption not exceeding 50% of the recommended intake. Iodine supplementation is usually necessary to prevent iodine deficiency disorders (IDDs), especially in endemic areas. The community-based strategy of iodine fortification in salt has eradicated IDDs, such as endemic goiter and cretinism, in countries providing adequate measures of iodine prophylaxis over several decades in the 20th century. Iodized salt is the cornerstone of iodine prophylaxis in endemic areas, and the continuous monitoring of community iodine intake and its related clinical outcomes is essential. Despite the relevant improvement in clinical outcomes, subclinical iodine deficiency persists even in Western Europe, especially among girls and women, being an issue in certain physiological conditions, such as pregnancy and lactation, and in people consuming unbalanced vegetable-based or salt-restricted diets. Detailed strategies to implement iodine intake (supplementation) could be considered for specific population groups when iodized salt alone is insufficient to provide adequate requirements.

Оценка йодной обеспеченности детей-вегетарианцев

Objective. To study the iodine supply of children on a vegetarian diet and to evaluate the effectiveness of iodized salt for the prevention of iodine deficiency. Methods. 65 vegetarian children( from 7 to 11 years) were examined. The control group included 40 healthy children of the same age which had no any dietary restrictions. All children lived in the Donetsk Republic. The study of iodine supply was carried out by determining the median of ioduria in the group. Taking into account the identified changes in the iodine supply of children of the surveyed groups, we prescribed them the prevention of iodine deficiency using iodised salt. The effectiveness was evaluated in 6 months. Results. In the main group, the median iodine was 68.4 μg/L, which is mild iodine deficiency. At the same time, 33.9% of children of the main group had a level of ioduria &lt;50 μg / l. In the control group, the median iodine was 97.1 μg/L. Ioduria &lt;50 μg/L had 25.0% of children. In 6 months from the beginning of iodised salt use in the main group, the median iodine was 107.8 μg/L, which is normal iodine supply, and the proportion of children with an iodine concentration in the urine &lt;50 μg/L was 16.9%. In turn, in the control group, after preventive use, the median iodine was 122.5 μg/L, and the proportion of children with ioduria &lt;50 μg/L decreased to 12.5%. Conclusion. The children living in the Donbass have a mild iodine deficiency. Vegetarianism without the use of iodised salt leads to an even more pronounced iodine deficiency. The received data allows to consider that vegetarian children have a risk of iodine deficiency. Regular iodized salt use is an effective prevention of iodine deficiency not only in traditionally fed children, but also in vegetarian children. Key words: vegetarianism, iodine, iodine deficiency, children, iodised salt

Assessing of iodine consumption with iodized salt in organized nutrition of children of preschool and school age in the Tyumen region

The territory of the Tyumen region is an endemic region with insufficient iodine content in the environment, in which, since the early 1990s, active preventive measures have been taken to increase the use of iodized salt (IS) in households, catering and the food industry. The purpose of the research was to assess the consumption of iodine with IS used in the organized nutrition of children in the Tyumen region. Material and methods. The assessment of iodine intake was carried out in preschool institutions and schools randomly selected the city of Tyumen and rural areas (village of Isetskoye). Modeling of iodine consumption in organized groups was carried out for children aged 1-3, 3-7, 7-11 and 12 years and older in urban and rural areas, respectively, using a standard menu and a technological map of dishes. Iodine intake was estimated based on the content of 40 μg of iodine in 1 g of salt and its 30% loss during cooking. Model 1 assumed the mandatory use of IS in the preparation of all salt-containing meals for preschoolers and schoolchildren. Model 2, in addition to the mandatory use of IS in school and preschool meals accounted the consumption of iodine with bakery products (BP) produced with IS. Results. The modeling showed that the average intake of iodine with meals (model 1) in preschool institutions in Tyumen was 89±16 μg/day for children aged 1-3 years. When BP with IS were included in the menu (model 2), iodine intake increased to 101±14 μg/day. In children aged 4-7 years iodine intake was 115±18 and 126±18 μg/day, respectively. In rural areas, iodine intake was lower: in children aged 1-3 years, under model 1, iodine intake was 66±3 μg/day, under model 2 - 76±4 μg/day. In children aged 4-7 years, these figures were 83±3 and 92±4 μg/day, respectively. Iodine consumption in a school in Tyumen under model 1 in children 7-11 years old was 24±5 μg/day, and in children 12 years and older - 27±6 μg/day. When BP with IS were included in the menu (model 2), iodine intake increased to 32±5 μg/day in children 7-11 years old and to 39±6 μg/day in children 12 years of age and older. In rural areas, when using model 1, iodine intake in children aged 7-11 years was 37±15 μg/day, in children aged 12 and over 40±21 μg/day. When BP with IS were included in the menu (model 2), iodine intake increased to 44±15 μg/day in children aged 7-11 years and to 50±21 μg/day in children 12 years of age and older. Conclusion. The use of IS in the preparation of salt-containing meals in preschool educational institutions of the Tyumen region fully covered the iodine requirements of preschool children, which confirms the effectiveness of the chosen strategy for the prevention of iodine deficiency and can be considered as an important part of the concept of universal salt iodization. The use of IS in preparation of school breakfast meals provides 23.5-36.9% of the recommended nutrient intake for iodine in rural schools and 15.4-26.4% of the recommended nutrient intake in urban schools, which can be a significant contribution to the total intake of this micronutrient.