Prevalence Rate Of Vitamin Research Articles

Correlation among Bone Health Profile, Vitamin D Status and Body Weight among Children and Adolescents in the Western Region of Saudi Arabia

Objective: Vitamin D deficiency related to obesity has significantly increased over the past 15 years and this has increased the risk for bone disease in children and adolescents. A sedentary lifestyle, with limited participation in outdoor activities, could exacerbate the effects of obesity on vitamin D deficiency. Therefore, the aim of our study was to evaluate the relationship between overweight/obesity and vitamin D deficiency among children in the western region of Saudi Arabia who have a relatively sedentary lifestyle due to high year-round temperatures. Methods: We conducted a cross-sectional study including 218 participants (114 girls, 104 boys), 2 to 18 years old, evaluated in our ambulatory endocrine clinics in Jeddah, Saudi Arabia, between September 2015 and March 2016. Serum levels of vitamin D, phosphorus, calcium and alkaline phosphates were evaluated in relation to body weight. Results: The mean age among children in our study group was 9.9 ± 3.9 years. A prevalence rate of vitamin D deficiency/insufficiency of 97.5% was identified (156/218 participants), with normal serum levels of vitamin D identified in only 4/218 participants (2.5%). Vitamin D levels were inversely related to body weight. High levels of alkaline phosphates were identified in 88.2% of participants, with levels of calcium and phosphorus being within normal ranges overall. Conclusion: Based on our results, increased surveillance for vitamin D deficiency/insufficiency and alkaline phosphates levels in children who are overweight and obese should be considered. Moreover, as children and adolescents in the western region of Saudi Arabia typically have low sun exposure due to limited outdoor activities, vitamin D supplementation, as indicated by screening outcomes, could improve bone health outcomes in children who are overweight and obese.

Déficit de vitamina D y morbimortalidad en pacientes críticos pediátricos

ObjectivesTo determine the prevalence and risks factors of vitamin D deficiency, as well as its relationship with morbidity and mortality in a PICU. Material and methodsAn observational prospective study in a tertiary children's University Hospital PICU conducted in two phases: i: cohorts study, and ii: prevalence study. The study included 340 critically ill children with ages comprising 6 months to 16 years old. Exclusion criteria: Chronic kidney disease, known parathyroid disorders, and vitamin D supplementation. Total 25-hydroxyvitamin D [25(OH)D] was measured in the first 48hours of admission to a PICU. Parathormone, calcium, phosphate, blood gases, blood count, C-reactive protein, and procalcitonin were also analysed. A record was also made of demographic features, characteristics of the episode, and complications during the PICU stay. ResultsThe overall prevalence rate of vitamin D deficiency was 43.8%, with a mean of 22.28 (95% CI 21.15–23.41) ng/ml. Patients with vitamin D deficiency were older (61 vs 47 months, P=.039), had parents with a higher level of academic studies (36.5% vs 20%, P=.016), were admitted more often in winter and spring, had a higher PRISM-III (6.8 vs 5.1, P=.037), a longer PICU stay (3 vs 2 days, P=.001), and higher morbidity (61.1% vs 30.4%, P<001) than the patients with sufficient levels of 25(OH)D. Patients who died had lower levels of 25(OH)D (14±8.81ng/ml versus 22.53±10.53ng/ml, P=.012). Adjusted OR for morbidity was 5.44 (95%CI; 2.5-11.6). ConclusionsVitamin D deficiency is frequent in critically ill children, and it is related to both morbidity and mortality, although it remains unclear whether it is a causal relationship or it is simply a marker of severity in different clinical situations.

The association between hypovitaminosis D and pediatric allergic diseases: A Korean nationwide population-based study.

There is still considerable disagreement regarding the role of vitamin D in the development or exacerbation of allergic diseases. To investigate the association between serum vitamin D levels and recent symptoms of allergic diseases in elementary schoolchildren. A nationwide cross-sectional survey was conducted in children ages 6-7 years from 45 randomly selected elementary schools. The presence of atopic dermatitis (AD) or asthma was defined as medical treatment of children for AD or asthma within 12 months of the survey. The presence of allergic rhinitis (AR) was defined as medical treatment for AR during the past 12 months and a positive skin test response. Current AD was defined as confirmed eczema on physical examination. Serum 25-hydroxyvitamin D (25[OH]D) was measured by chemiluminescent immunoassay. Questionnaire data and blood samples were collected from 3720 children. The overall prevalence rates of vitamin D insufficiency (20-29 ng/mL) and deficiency (<20 ng/mL) were 64.0% and 18.4%, respectively. For a 1 ng/mL decrease in 25(OH)D, the adjusted odds ratio (aOR) for AR was 1.020 (95% confidence interval [CI], 1.002-1.040) and the aOR for current AD was 1.027 (95% CI, 1.006-1.047). For each 1 ng/mL decrease in 25(OH)D, the aOR for positive skin-prick test reactivity was 1.013 (95% CI, 1.000-1.027). No significant association between vitamin D level and the prevalence of asthma was observed. A high prevalence of vitamin D deficiency and insufficiency was found in Korean elementary schoolchildren, and low vitamin D levels were associated with recent symptoms of AD and AR.

The persistence of maternal vitamin D deficiency and insufficiency during pregnancy and lactation irrespective of season and supplementation.

Pregnancy and lactation comprise a critical window spanning all seasons during which maternal vitamin D status potentially may influence the long-term health of the newborn. Women typically receive calcium/vitamin D supplementation through antenatal vitamins, but there has been limited serial evaluation of maternal vitamin D status across this critical window. In this prospective observational cohort study, 467 women in Toronto, Canada, underwent measurement of serum 25-hydroxy vitamin D (25-OH-D) at mean 29·7 ± 2·9 weeks' gestation, 3 months postpartum and 12 months postpartum, enabling serial assessment across 3 seasons. At each assessment, vitamin D status was classified as deficiency (25-OH-D<50 nmol/l), insufficiency (25-OH-D≥50 nmol/l and <75 nmol/l) or sufficiency (25-OH-D≥75 nmol/l). The prevalence rates of vitamin D deficiency and insufficiency were 31·5% and 35·1% in pregnancy, 33·4% and 35·3% at 3 months, and 35·6% and 33·8% at 12 months postpartum, respectively. These high rates remained stable over time (P = 0·49) despite declining usage of antenatal calcium/vitamin D supplementation from pregnancy to 3 months to 12 months postpartum (P < 0·001). Indeed, on mixed model analyses, vitamin D deficiency and insufficiency in pregnancy were independently associated with decrements in average 25-OH-D over time of 49·6 nmol/l and 26·4 nmol/l, respectively (both P < 0·001). In contrast, season of baseline assessment and use of calcium/vitamin D supplements were independently associated with changes in 25-OH-D in the range of 3-5 nmol/l (both P < 0·008). The persistence of vitamin D deficiency/insufficiency during pregnancy and lactation, irrespective of season and supplementation, supports the emerging concept that current vitamin D supplementation in antenatal care is likely inadequate.

The Effect of Vitamin D Levels on Pediatric Allergic Diseases: A Nationwide Population-Based Study

Hea-Kyoung Yang, Jaehee Choi, Woo Kyung Kim, So-Yeon Lee, MD, Yong Mean Park, Man-Yong Han, MD, Myung-Il Hahm, Yoomi Chae, Hye-young Kim, Kang Mo Ahn, MD, HoJang Kwon, MD, PhD, Jihyun Kim, MD; Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Environmental Health Center for Atopic Diseases, Samsung Medical Center, Seoul, Korea, Environmental Health Center for Atopic Diseases, Department of Pediatrics, Samyook Medical Center, Seoul, South Korea, Department of Pediatrics, Inje University College of Medicine, Seoul, Korea, Department of Pediatrics, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Department of Pediatrics, Hallym University Secred Heart Hospital, Anyang, South Korea, Kunkuk University Hospital, South Korea, CHA University Bundang Medical Center, Seongnam, South Korea, Department of Health Administration and Management, College of Medical Science, Soonchunhyang University, Asan, Korea, Department of Occupational and Environmental Medicine, College of Medicine, Dankook University, Department of Pediatrics, Pusan National University School of Medicine, Busan, Korea, Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, South Korea, Preventive Medicine, Dankook University College of Medicine, Cheonan, South Korea, Dankook University, Cheonan, Environmental Health Center for Atopic Diseases, Seoul, South Korea, Department of Pediatrics, SamsungMedical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. RATIONALE: We aimed to investigate the association between concentration of serum vitamin D levels and recent symptoms of allergic diseases in elementary schoolchildren. METHODS: A nationwide cross-sectional survey was conducted in the first grade students from randomly selected 45 elementary schools. Recent symptoms of atopic dermatitis (AD) or asthma were defined as those who were medically treated for AD or asthma. Recent symptoms of allergic rhinitis (AR) were considered to be present if a child had the experience of treatment for AR during the last 12 months and showed a positive skin prick test responses to common 18 inhalant allergens. All the children were examined by a pediatrician to determine the presence of eczema in their neck and flexural areas of both arms. Serum 25-hydroxyvitaminD [25(OH) D] was measured by chemiluminescent microparticle immunoassay. RESULTS: The overall prevalence rates of vitamin D insufficiency (20 to 29 ng/mL) and deficiency (<20 ng/mL) were 64.1% and 18.4%. The adjusted odds ratio (aOR) for the presence of AR was 0.980 (95% CI: 0.962–0.998) for each increase of 1 ng/mL in 25(OH)D, while no association was found between 25(OH)D levels and the prevalence of AD or asthma. The aOR per increase of 1 ng/mL in 25(OH)D was 0.974 (95% CI 0.955-0.994) for the presence of eczema on the day of survey. CONCLUSIONS: A high prevalence of vitamin D deficiency and insufficiency was found in Korean elementary schoolchildren, and vitamin D level was associated with recent symptoms of AD and AR. 186 Clinical and Epidemiological Differences in Patients with Acute Urticaria and Chronic Urticaria Mehtap Haktanir Abul, MD, Fazil Orhan, Zekiye Ilke Kilic Topcu, Taner Karakas, Ali Baki; Karadeniz Technical University Faculty of Medicine Department of Pediatric Immunology and Allergy, Trabzon, Turkey, Karadeniz Technical University Faculty of Medicine Department of Pediatric Immunology and Allergy, Karadeniz Technical University Faculty of Medicine Department of Pediatric Pulmonology. RATIONALE: Urticaria is commonly seen and it is difficult to determine the etiologic factors in children. The aim of the study is to define different clinical patterns of urticaria in childhood. METHODS: This is a prospective study included the children who were referred to our clinic for evaluation of urticaria. Laboratory tests including serologic, autoimmune, and allergic analyses were conducted. RESULTS: One hundred and eighty two children (90 females and 92 males) were evaluated. The age range was 4 month17 years old. Of the cases, 58.2 % (n5106) were diagnosed with acute urticaria and 41.8 % (n576) were diagnosed with chronic urticaria. There wasn’t any significant difference in gender between acute and chronic urticaria group. The median agewas 5 years (range: 4month16 years old) and 6.5 years (range: 7 month17 years old) for acute and chronic urticaria groups respectively. CRP, IgE, eosinophil, C3 and C4 levels are higher in acute urticaria than chronic urticaria patients that were not statistically significant. Physical urticaria was commonly seen in children with chronic urticaria (48.7%). Spontaneous resolution is more frequently seen in acute urticaria patients than the chronic urticaria patients (p50.016). CONCLUSIONS: There are clinical and epidemiological differences in patients with acute urticaria and patients with chronic urticaria. Recurrence, spontaneous resolution seems to be the factors associated with the differences in both group of patients. Physical urticaria is commonly seen and should be questioned in childrenwith chronic urticaria.

Vitamin D Levels and Sociodemographic and Clinical Correlates in Individuals With Serious Mental Illness Admitted to an Acute Psychiatry Unit

To describe the prevalence of vitamin D deficiency in psychiatric inpatients with serious mental illness. Associated clinical and sociodemographic factors are also explored. Data were collected using a retrospective review of medical records. Eligible subjects were individuals aged ≥ 18 years who were consecutively newly admitted to an adult inpatient teaching unit of a state psychiatric hospital from July 2012 through August 2013. The main outcome measure was prevalence rate of vitamin D deficiency in the target population. Vitamin D deficiency was defined as a level < 20 ng/mL. Psychiatric diagnoses were established using DSM-IV-TR criteria. Of 85 subjects, approximately two-thirds (67%) had a vitamin D level < 20 ng/mL. The mean vitamin D level was 18.4 ng/mL. Among the sociodemographic and clinical factors analyzed, only total serum protein (odds ratio = 0.33; CI, 0.12-0.88; P < .05) was associated with vitamin D deficiency. The high prevalence of vitamin D deficiency with all the attendant physical and mental health burdens in vulnerable populations such as individuals with serious mental illness requires further large research studies. In the meantime, it seems prudent to institute routine screening for vitamin D deficiency in individuals with mental illness, especially those who are hospitalized.

Vitamin D levels in hospitalised children of Southern Italy: A relationship with cause of admittance?

25-hydroxyvitamin D (25OHD) concentration was assessed and Vitamin D status was defined as follows: deficiency with serum 25OHD<10ng/ml, insufficiency between 10 and 29.9ng/ml, sufficiency with serum 25OHD between 30 and 100ng/ml. Collected data included age, gender and season of hospitalization. Results: Mean level of serum 25 OHD in our population was 21.34±10.24ng/ml. SignificantvitaminDvariationswere recorded according to season in which blood samples were drawn, mean levels were: 18.6±10ng/ml during winter, 18.9±7.8ng/ml during spring, 27.8±11.2ng/ml during summer, 21.3±10.2 during autumn (p<0.001). The prevalence rates of vitamin D deficiency, insufficiency and sufficiency during summer were: 1.8%, 66.3% and 31.9% respectively. Conclusions: Vitamin D levels are strongly influenced by seasonality, but according to our results only 31.9% of children presented sufficient pattern during summer. It’s important to establish screening, supplementation guidelines and pediatric cut-off levels to optimize vitamin D status in children.

Vitamin D supplementation-clarity required regarding treatment regimens and target plasma levels

The discovery of vitamin D at the beginning of the twentieth century was the result of pioneering work by numerous researchers investigating the role of vitamins and other factors in disease prevention. This culminated in Adolf Windaus being awarded the Nobel Prize for Chemistry in 1928 for his work on steroid chemistry and vitamins.1 Vitamin D deficiency is prevalent in healthy adults and is particularly high among black and Asian subjects living at higher altitudes. The National Health and Nutritional Examination Survey 2006 reports an overall prevalence rate of vitamin D deficiency of 41% in US adults.2 Older people and those who are institutionalized are more likely to have vitamin D deficiency and a UK survey found that only 16.2% of men and 13.2% of women aged ≥65 years had serum 25(OH)D levels ≥75 nmol/l.3 It is apparent but poorly understood that a strong association exists between socio-economic disadvantage and poor health in northern Europe and North America. Grimes4 suggests that poorer health and shorter life expectancy of the socio-economically disadvantaged in the UK may be partially explained by an association with the relative deficiency of vitamin D. Very few foods contain vitamin D2 or vitamin D3 and therefore, unlike other vitamins, humans rely primarily on sun exposure to obtain vitamin D. Vitamin D exerts its action through vitamin D receptors which are found in most cellular tissues. These receptors have a wide range of important biological actions including inhibition of cellular proliferation and induction of terminal differentiation, inhibition of angiogenesis, stimulation of insulin production, inhibition of renin production and stimulation of macrophage cathelicidin production.4 Vitamin D is therefore essential for normal calcium homeostasis but also has many other roles in cellular metabolism including modulation of cell growth, neuromuscular and immune function and reduction of …

Less than Adequate Vitamin D Status and Intake in Latin America and the Caribbean: A Problem of Unknown Magnitude

The prevalence of vitamin D deficiency in Latin America and the Caribbean is unknown. To examine the prevalence data available on vitamin D deficiency in Latin America and the Caribbean. A systematic review was conducted in 2011. Studies using biochemical biomarkers and dietary intake estimation were included. Studies conducted in apparently healthy individuals, independently of age, latitude, skin pigmentation, and season of the year at the time of blood collection, were included. A total of 243 studies were identified. The final number of selected studies was 28, including two National Health Surveys (Mexico and Argentina). There are studies that report the vitamin D status of specific subgroups conducted in Argentina, Brazil, Chile, Colombia, Ecuador, Guatemala, and Mexico. However, the small sample sizes in these studies and thus the low national representativeness of the reported data do not allow for an accurate assessment of vitamin D status at the regional level. In the majority of the countries with available data, we observed that vitamin D insufficiency was classified as a mild, moderate, or severe public health problem. The only country with a nationally representative sample was Mexico, which found 24%, 10%, 8%, and 10% prevalence rates of vitamin D insufficiency (25-hydroxyvitamin D < 50 nmol/L) in preschoolers, schoolchildren, adolescents, and adults, respectively. The prevalence of vitamin D deficiency (25-hydroxyvitamin D < 20 nmol/L) was less than 1% for all groups. There is some indication that vitamin D insufficiency may be a public health problem in Latin America and the Caribbean, but the exact magnitude is currently unknown.

Breast cancer and vitamin D in postmenopausal minorities.

17 Background: Bone health is a particular concern for breast cancer survivors, because these women have 15% higher fracture risk than women without a history of breast cancer. Many studies have suggested that vitamin D deficiency may be involved in breast cancer initiation, progression, and prognosis. This study examines the prevalence of vitamin D deficiency among postmenopausal breast cancer patients in minority population. Methods: This retrospective study reviewed the electronic records of 200 postmenopausal breast cancer patients from ethnic groups of blacks, Hispanics and Asians. Results: Of the 200 patients, 84 (42%) had their 25-OHD levels checked at least once. Of patients, 42.7% found body mass index (BMI)&gt;30kg/m2. There was significant difference between race and BMI (p&lt;0.05). Black Vitamin D deficiency (level&lt; 20ng/mL) found in 35 (41.7%), vitamin D insufficiency (level range 20-30ng/mL) found in 30 (35.7%) of the patients. The median serum 25-OHD level was 21 (range 4-65ng/ml). The serum 25-OHD levels did not have significant difference among blacks and Hispanics. Tumor stages found negatively correlated with 25-OHD levels r=-0.227 and p=0.04. Conclusions: This study revealed that vitamin D deficiency has a high prevalence among postmenopausal breast cancer minority population. Data from Third National Health and Nutrition Examination survey showed that mean serum 25-OHD levels among white, Hispanic and black women were 76ng/ml, 56.7ng/ml and 45.3ng/ml, respectively. Also, prevalence rate of vitamin D deficiency is reported in the studies among breast cancer patients are approximately 30%. Our data compared with this general population’s numbers is low; our median 25-OHD level was 21ng/ml. Our study found negative correlation with Vitamin D levels and stages of the breast cancer. Information is lacking on direct prognostic effect of vitamin D in breast cancer but this findings including our study support the hypothesis that vitamin D has a role in the pathogenesis of breast cancer. In the setting of breast cancer diagnosis either for bone health, or for breast cancer prognosis in postmenopausal women, we advocate routine 25-OHD levels screening for the vitamin D deficiency especially in minority populations would be beneficial.

Relative Vitamin D Insufficiency in Hashimoto's Thyroiditis

Vitamin D insufficiency, defined as serum levels of 25-hydroxyvitamin D [25(OH)D3] lower than 30 ng/mL, has been reported to be prevalent in several autoimmune diseases such as multiple sclerosis and type 1 diabetes mellitus. The goal of the present study was to assess whether vitamin D insufficiency is also a feature of Hashimoto's thyroiditis (HT). We performed a prevalence case-control study that included 161 cases with HT and 162 healthy controls. Serum levels of 25(OH)D3, calcium, phosphorus, and parathyroid hormone were measured in all 323 subjects. The prevalence of vitamin D insufficiency in HT cases (148 of 161, 92%) was significantly higher than that observed in healthy controls (102 of 162, 63%, p < 0.0001). Among HT cases, the prevalence rate of vitamin D insufficiency showed a trend to be higher in patients with overt hypothyroidism (47 of 50, 94%) or subclinical hypothyroidism (44 of 45, 98%) than in those with euthyroidism (57 of 66, 86%), but the differences were not significant (p = 0.083). Vitamin D insufficiency is associated with HT. Further studies are needed to determine whether vitamin D insufficiency is a casual factor in the pathogenesis of HT or rather a consequence of the disease.

Prevalence and correlates of vitamin D deficiency in US adults.

Mounting evidence suggests that vitamin D deficiency could be linked to several chronic diseases, including cardiovascular disease and cancer. The purpose of this study was to examine the prevalence of vitamin D deficiency and its correlates to test the hypothesis that vitamin D deficiency was common in the US population, especially in certain minority groups. The National Health and Nutrition Examination Survey 2005 to 2006 data were analyzed for vitamin D levels in adult participants (N = 4495). Vitamin D deficiency was defined as a serum 25-hydroxyvitamin D concentrations ≤20 ng/mL (50 nmol/L). The overall prevalence rate of vitamin D deficiency was 41.6%, with the highest rate seen in blacks (82.1%), followed by Hispanics (69.2%). Vitamin D deficiency was significantly more common among those who had no college education, were obese, with a poor health status, hypertension, low high-density lipoprotein cholesterol level, or not consuming milk daily (all P < .001). Multivariate analyses showed that being from a non-white race, not college educated, obese, having low high-density lipoprotein cholesterol, poor health, and no daily milk consumption were all significantly, independently associated with vitamin D deficiency (all P < .05). In summary, vitamin D deficiency was common in the US population, especially among blacks and Hispanics. Given that vitamin D deficiency is linked to some of the important risk factors of leading causes of death in the United States, it is important that health professionals are aware of this connection and offer dietary and other intervention strategies to correct vitamin D deficiency, especially in minority groups.

Vitamin D Deficiency in the Southern United States

Vitamin D Deficiency in the Southern United States

Serum 25-hydroxyvitamin D status of adolescents and adults in two seasonal subpopulations from NHANES III

Subclinical vitamin D deficiency may be common in certain subgroups in the U.S., but to date vitamin D data from other groups in the population have not been available. We used serum 25-hydroxyvitamin D (25-OHD) data from 18,875 individuals examined in the Third National Health and Nutrition Examination Survey (NHANES III 1988–1994) to assess the vitamin D status of selected groups of the noninstitutionalized U.S. adolescent and adult population. Serum 25-OHD levels were measured by a radioimmunoassay kit (DiaSorin, Inc., Stillwater, MN; normal range 22.5–94 nmol/L). Because physical exams are performed in mobile vans in NHANES, data could not be collected in northern latitudes during the winter; instead data were collected in northern latitudes during summer and in southern latitudes in winter. To address this season-latitude aspect of the NHANES design, we stratified the sample into two seasonal subpopulations (winter/lower latitude and summer/higher latitude) before examining vitamin D status. Less than 1% of the winter/lower latitude subpopulation had vitamin D deficiency (25-OHD <17.5 nmol/L). However, the prevalence of vitamin D insufficiency in this group ranged from 1%–5% with 25-OHD <25 nmol/L to 25%–57% with 25-OHD <62.5 nmol/L, even though the median latitude for this subsample (32°N) was considerably lower than the latitude at which vitamin D is not synthesized during winter months (∽42°N). With the exception of elderly women, prevalence rates of vitamin D insufficiency were lower in the summer/higher latitude subpopulation (<1%–3% with 25-OHD <25 nmol/L to 21%–49% with 25-OHD <62.5 nmol/L). Mean 25-OHD levels were highest in non-Hispanic whites, intermediate in Mexican Americans, and lowest in non-Hispanic blacks. Our findings suggest that vitamin D deficiency is unlikely in the two seasonal subpopulations of noninstitutionalized adolescents and adults that can be validly assessed in NHANES III. However, vitamin D insufficiency is more common in these two seasonal subpopulations. Of particular interest is that insufficiency occurred fairly frequently in younger individuals, especially in the winter/lower latitude subsample. Our findings support continued monitoring of this vitamin in the U.S. population.

Bounded efficient markets

<h3>Objectives</h3> To investigate the prevalence of vitamin D deficiency among individuals attending primary healthcare facilities in Qatar and to assess the association between vitamin D deficiency and some medical conditions in persons aged 18–65 years old. <h3>Setting</h3> The study was undertaken in publicly funded primary healthcare services in the State of Qatar. <h3>Participants</h3> A total of 102 342 participants aged between 18 and 65 years old with a valid serum vitamin D test result during the year 2017. <h3>Outcome measures</h3> Serum level &lt;10 ng/mL (&lt;25 nmol/L) was defined as severe vitamin D deficiency, a serum level of &lt;20 ng/mL (&lt;50 nmol/L) was defined as vitamin D deficiency and a serum level &lt;30 ng/mL (&lt;75 nmol/L) defined as vitamin D insufficiency. <h3>Results</h3> The prevalence rate of severe vitamin D deficiency was 14.1% among study participants with no history of vitamin D replacement therapy in the previous months. The prevalence rate of vitamin D deficiency was as high as 71.4% and that of vitamin D insufficiency was up to 92.7%. None of the five chronic conditions explored in the study (diabetes, hypertension, asthma, stroke and cardiovascular disease) had an obvious association with severe vitamin D deficiency status in a bivariate analysis. However, multivariate modelling showed that (adjusting for age, gender, body mass index and nationality and each of the included chronic conditions) hypertension, cardiovascular diseases and stroke placed an individual at a higher risk of having an associated severe vitamin D deficiency status. <h3>Conclusion</h3> Although not comprehensive and nationally representative, this study is suggestive of a higher prevalence of vitamin D deficiency among young adults, females, Qatari nationality and those with higher body mass index. Multivariate modelling showed that hypertension, cardiovascular diseases and stroke were associated with a higher risk of severe vitamin D deficiency status.