You have accessJournal of UrologyStone Disease: Epidemiology & Evaluation I1 Apr 2018MP13-13 STONE COMPOSITION IN PEDIATRIC PATIENTS PRESENTING TO A MULTI-DISCIPLINARY STONE CLINIC Alison C. Keenan, MD, Thomas G. Leffler, MPH, and Kristina L. Penniston, PhD, RD Alison C. Keenan, MDAlison C. Keenan, MD More articles by this author , Thomas G. Leffler, MPHThomas G. Leffler, MPH More articles by this author , and Kristina L. Penniston, PhD, RDKristina L. Penniston, PhD, RD More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.485AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The composition of pediatric kidney stones is suspected to be similar to adults with approximately 75-80% being primarily calcium oxalate (CaOx) and 5-10% calcium phosphate (CaP). We aimed to assess the stone composition of pediatric patients presenting to a multi-disciplinary stone clinic. METHODS A retrospective chart review of 118 patients who presented to a multi-disciplinary pediatric stone clinic was conducted. The main inclusion criterion was that the patient had to have a stone composition recorded in the medical record. If patients had more than 1 stone composition, then the first reported composition was used for analysis in an effort to select as much as possible for patients naïve to medical management. Stones were defined as predominantly CaOx or CaP if they met or exceeded 50%. A 2-sided Pearson Chi-Square test was used for comparison of categorical variables. A p-value <0.05 was considered significant. RESULTS Forty-six patients were included in the analyses (20 male, 26 female). Nine had multiple stone compositions recorded. Nineteen patients reported a family history of stones. Mean age at initial clinic visit was 12.6 ± 4.4 years (range, 2.5-19.1 years). Mean body mass index (BMI) was 22.6 ± 8 kg/m2. Of the 46 stone compositions analyzed, 26 (57%) were predominantly CaOx stones and 10 (22%) were predominantly CaP stones. The majority of reported stones (40/46; 87%) had some combination of CaOx and CaP. On average, stones were 35% CaOx (range, 2-99%) and 28% CaP (range, 1-98%). Ammonium urate was the predominant species in 1 patient’s stone. There was no significant difference between sex (male, female), age group (=12 years old, >12 years old), family history of stones (yes, no), and BMI (underweight, normal, overweight, obese) for prevalence of CaOx stones (p>0.18 for all comparisons). Girls had a tendency for more CaP stones than boys (p=0.056). CONCLUSIONS The majority of patients presenting to our multi-disciplinary pediatric stone clinic had primarily mixed calcium stones (CaOx and CaP). Girls tended to have a higher prevalence than boys of CaP stones. When comparing overall average stone composition of this pediatric cohort to that of U.S. adults, the prevalence of predominantly CaP stones (22%) was higher than expected. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e176 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Alison C. Keenan, MD More articles by this author Thomas G. Leffler, MPH More articles by this author Kristina L. Penniston, PhD, RD More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...