Purpose: Epworth HealthCare amalgamated the renal dialysis and day oncology units in 2012 in a purpose built area within a 700 bed acute hospital. Infection Prevention has monitored the patient infection rates and outcomes before and after the amalgamation to understand the impact of co horting the specialties. Methods: The planning to combine the two areas began in 2010 with major research investigation and networking review to identify previous infection related outcomes from similar specialty amalgamations. Nil evidence was identified. Epworth planned and built this model of care around a zoned separation using four chair areas. The remainder of the unit is a shared space including waiting areas, clean and dirty utility rooms, medication and pantry areas. The unit has share staff services for cleaning, food delivery, laundry and waste management. The area consists of twelve dedicated dialysis chairs and twenty oncology chairs with a four chair that can be used for either specialty with in excess of 280 patient attendances per week. All infections are reviewed including bacteraemias and multi resistant organisms using definitions accepted for hospital surveillance to define either community acquired or hospital acquired. The method used is daily pathology results review, daily area rounding and an automated weekly readmission with infection report. There has been twice yearly ad hoc microbiology plating undertaken in the area. Results: The review of all patient infections resulted in none that was attributable to the patient placement in the unit. Prior to the unit amalgamation there were two line related infections identified in twelve months. There was no clinical practice change in the three years. Conclusions: Although we cannot say there is no risk, there is no evidence to date to recommend the cohabitation should not continue.