Prevalence Of Raynaud's Phenomenon Research Articles

SP0170 Clinical Manifestations of Raynaud's Phenomenon during Different Ages

Raynaud's phenomenon (RP) is an exaggeration of the normal physiological response to cold. Typically the fingers turn white (ischaemia), then blue (deoxygenation) and then red (reperfusion). The toes (and nose...

SP0112 Clinical Manifestations of Raynaud's Phenomenon during Different Ages

Raynaud's phenomenon (RP) is an exaggeration of the normal physiological response to cold. Typically the fingers turn white (ischaemia), then blue (deoxygenation) and then red (reperfusion). The toes (and nose...

Prevalence of Raynaud's phenomenon in young Greek males

The aim of this paper is to study the prevalence of Raynaud's phenomenon in young males. Young males were examined prospectively in a district hospital, and laboratory tests were performed on the basis of the clinical history. Young males (3.912), age 18-28 years old, were examined. Raynaud's phenomenon was present in seven men (1,79 per 1.000, 95% CI 0.72-3.68). Three of them had at least one member in their family diagnosed with Raynaud's phenomenon. Three were smokers. All had negative immunological test. Five patients reported having severe attacks and two had only mild ischemic attacks. The treatment was conservative for all patients, two of them necessitated vasodilators. Very low prevalence of Raynaud's phenomenon was observed in this young male group compared with the previous studies.

Occurrence of Raynaud's phenomenon in children ages 12–15 years: Prevalence and association with other common symptoms

Although Raynaud's phenomenon (RP) in adults is frequently reported as having been present since childhood, there have been no studies on the prevalence of RP in children. This study was undertaken to ascertain the prevalence of RP in children ages 12-15 years and to determine whether, as with other commonly reported symptoms, there were any associations with adverse psychosocial factors. A previously validated self-administered RP questionnaire was distributed to 903 children ages 12-15 years, from 28 schools. The questionnaire also included questions on other common childhood symptoms and on adverse psychosocial factors. Seven hundred twenty children responded (80%), in whom the prevalence of RP was 15%. This was higher in girls (18% versus 12%) and increased with age. After adjustment for age and sex, there was an association with reporting of current pain, both in the arm/shoulder region and elsewhere in the body. There were no associations with psychosocial variables. RP is frequent in children ages 12-15 years. Unlike other common childhood symptoms, RP showed no association with psychosocial factors in this study.

Raynaud's phenomenon in idiopathic carpal tunnel syndrome

In a previous study the prevalence of Raynaud's phenomenon (RP) in patients with idiopathic carpal tunnel syndrome (CTS) was found to be 60% which is much higher than that in the general population. We undertook a further study of the same cohort of patients have both CTS and RP and who had an open release of the carpal tunnel, to observe the effects of the operation on RP. We observed whether the symptoms of RP improved, and repeated the cold provocation tests to see if the arterial pulse which was decreased before operation would recover. We rated the outcome as good when the patients showed both an improvement of the symptoms of RP and a normal pulse amplitude after exposure to cold, fair when the pulse amplitude recovered to more than two-thirds of that before exposure, and poor when cold hypersensitivity was persistent or showed the same degree of decreased pulse amplitude as observed before operation. Of the 18 patients with both conditions, ten (56%) had good and four (22%) fair results, with a mean recovery time of 4.2 months (6 weeks to 1 year) after operation. If the vasospasm seen in RP is an expression of vasomotor irritation in the carpal tunnel, these findings suggest that local compression of vasomotor fibres in the carpal tunnel can also be relieved by the release of this structure. Careful consideration, however, is still required in treating patients with both conditions since in some cases. RP may be superimposed or it may have other origins.

B112 振動工具取扱い者に対する長期間にわたる健康管理への取り組み(第2報)

B112 振動工具取扱い者に対する長期間にわたる健康管理への取り組み(第2報)

Raynaud's phenomenon in older adults: diagnostic considerations and management.

Raynaud's phenomenon (RP) is characterised by sensitivity to cold temperatures associated with either biphasic or uniphasic change in colour of the digits. Since few studies are available which include older adults, the prevalence of RP in the older adult population is estimated from surveys or studies of the general population. The causes of RP in older adults may differ significantly from those in young adults and, therefore, so would the evaluation of RP. Because of comorbitis that accompany advancing age, the management of RP in older adult patients must take into consideration toxicity and adverse reactions that may develop, especially in the frail individual. Although nonpharmacological therapy is preferable, slow-release calcium antagonists provide a relatively well tolerated and effective treatment for moderate to severe RP in older adult patients. Aggressive treatment including hospitalisation is appropriate for older adult patients during periods of critical digital ischaemia associated with RP.

Prevalence of Raynaud Phenomenon in Tartu and Tartumaa, Southern Estonia

The aim of the present study w; is to estimate the prevalence of Raynaud phenomenon (RP) among Fsronians in the general population ol Southern Estonia.A random sample of 2626 Estonian subjects from the general population was asked about their fingers' sensitivity to cold and color changes by a mail survey. A stibsample of 457 subjects was examined to confirm the diagnosis of” RP. using a standard interview assisted by colo charts (a color scale and hand photographs). In addition to a short clinical examination, the nailfold capillaries were examined by in vivo microscopy and a blood sample was drawn for ANA testing.The prevalence of RP, based on ihe presence of blanching, alone or with cyanosis, was 8.3% ± 0.91% (SE) lor women and 7.9-1.62% for men. The prevalence increased with age and, in men, was related to occupation. Smoking was also associated with RP among men but the effect was difficult to separate from that of the occupational influences because of the high proportion (84.2%) of current and past smokers among male manual workers.RP among the Estonians in Southern Estonia has a lower prevalence than in other countries with comparable climate, its female to male ratio is low, and it is related to occupation and smoking in men.

Pathophysiology of Vibration‐Induced White Finger and Safety Levels for Hand‐Transmitted Vibration

Pathophysiology of Vibration‐Induced White Finger and Safety Levels for Hand‐ Transmitted Vibration: Ryoichi Inaba, et al. Department of Hygiene, Gifu University School of Medicine—This review addresses the pathogenic mechanism and vibration safety values of vibration‐ induced white finger (VWF). Sympathetic hyperactivity alone has long been postulated to account for VWF, but damage to vasoregulatory structures and functions in the finger skin now also seems to be involved. The physiological complexity of the response to cold is so great and the interaction between various vasoregulatory mechanisms so intricate that only a multifactorial etiology and pathogenesis is likely for VWF. These factors will be discussed in detail. Regarding vibration safety values, the prevalence of VWF and vibration magnitude (hand‐transmitted vibration levels (HTVLs)) in various groups of workers which reported in our previous studies were reviewed. The prevalence rates of VWF were compared to the prevalence rates of Raynaud's phenomenon (RP) in a large group of males and females without vibration exposure. It was observed that in subjects exposed to HTVLs of between 1.1 and 2.5 m/s2, the prevalence of VWF was 0.0‐4.8%. The prevalence of VWF in workers exposed to HTVLs of up to 5.1 m/s2 was 9.6% and significantly higher than the prevalence of RP in males in the general population (2.7%). A significant positive correlation between VWF and HTVLs values was obtained. By employing the results obtained on vibration magnitude and the prevalence of VWF, estimated vibration safety levels are discussed.

Prevalence of Raynaud's phenomenon in different groups of workers operating hand-held vibrating tools.

In eight groups of subjects operating various hand-held vibrating tools and aged from 30 to 59 years, the prevalence rates of vibration-induced white finger (VWF) and numbness, pain, or stiffness in the upper and lower extremities were investigated. Hand-transmitted vibration levels (HTVLs) were measured on the back of the hand, by means of unidirectional (x-axis) vibration dosimeters, and the frequency-weighted acceleration levels [(Lh,w)eq,t] were determined as the vibration levels. The prevalence rates of VWF and numbness of the hands in these subjects were compared to the prevalence rates of Raynaud's phenomenon (RP) and numbness of the hands in 1027 males and 1301 females not occupationally exposed to vibration (age range: 30-59 years). It was observed that in subjects exposed to HTVLs of between 1.1 and 2.5 m/s2, the prevalence of VWF was between 0.0% and 4.8%. The prevalence of VWF reached 9.6% in a group of workers exposed to HTVLs of 2.7-5.1 m/s2. The latter group showed a significant difference (P < 0.05) in the prevalence of VWF compared to the 2.7% prevalence of RP in male subjects of the general population. The prevalence of VWF in female subjects exposed to vibration (4.3%) was not significantly different from the prevalence of RP in females of the general population (3.4%). The prevalence rates of numbness of the hands were in the range of 6.5%-30.4% in the exposed groups and in the range of 13.4%-29.5% in the general population. Among the subjective symptoms, only VWF showed a significant positive correlation with HTVLs (R2 = 0.5, P < 0.05). It was concluded that in decisions concerning quantitative recommendations for vibration exposure, the prevalence of VWF should be employed. With a view to decreasing the risk of developing VWF, estimated vibration safety values for 4 h and 2 h daily exposures are discussed.

Prevalence of Raynaud's phenomenon and specific clinical signs related to progressive systemic sclerosis in the general population of Japan.

In order to evaluate the prevalence rates of Raynaud's phenomenon (RP) and specific clinical signs related to progressive systemic sclerosis (PSS) in the general population of Japan, inquiries were made concerning RP in the hands and dermatologic examinations were also conducted. One thousand and sixty-three subjects (332 men and 731 women) over 30 years of age who underwent inhabitants' health examinations in 1990 were considered for this study. The prevalence of RP was 3.0% in men and 3.4% in women. In 8 men and 17 women with RP who received the blood tests, the positive rates of antinuclear antibody (ANA) were 12.5% and 35.3% in men and women, respectively. The prevalence rates of all five specific clinical signs related to PSS, sclerodactyly, pitting scars of the fingers, brown pigmentation of the body, shortened frenulum of the tongue, and flexion contracture of fingers, were under 2% in men and 3% in women. In women with RP the prevalence rates of sclerodactyly, pitting scars of the fingertips, brown pigmentation of the body, and shortened frenulum of the tongue were 16.0, 4.0, 4.0, and 16.0%, respectively. These values were significantly higher than those of persons without RP. Because some persons with primary RP may become typical cases of PSS within several years, a followup study, particularly for women who have positive titers of ANA with RP, should be carried out to find out whether the persons suffer from PSS or not.

Prevalence of raynaud phenomenon in the adult population of South Carolina

A prevalence estimate for Raynaud phenomenon among adult residents of South Carolina was based on data obtained from respondents in a statewide health survey, followed by face-to-face interviews and clinical screening for Raynaud phenomenon, using a screening procedure developed by the authors. The survey obtained 5246 personal interviews from a probability sample of over 3000 households, and 494 survey subjects participated in the clinical screening. The prevalence estimates and their standard errors were computed using survey case weights, design-based estimation, and logistic modelling techniques. The prevalence of Raynaud phenomenon among adult residents of South Carolina was determined to be 3.5%, with a standard error of 0.6%. Prevalence was higher for females (4.3%, SE = 0.7%) than for males (2.7%, SE = 0.6%), These figures are much lower than most estimates in the existing literature on Raynaud phenomenon.