Prevalence Of Joint Hypermobility Syndrome Research Articles

Joint Hypermobility Syndrome: A Narrative Review

Joint hypermobility syndrome (JHS) is a complex connective tissue disorder characterized by excessive joint mobility and chronic musculoskeletal pain. The condition extends beyond the joints and can affect various systems such as the skin, gastrointestinal tract, neurological system, and cardiovascular system, necessitating a multidisciplinary approach to optimize care. Notably, the prevalence of JHS is higher in young individuals, females, and those of Asian descent. Despite being a common condition, JHS is frequently underdiagnosed, resulting in persistent pain and disability. In order to diagnose JHS, it is necessary to rule out the presence of any consistent feature that indicates the existence of other connective tissue disorders that partially overlap with it, including Marfan and Ehlers-Danlos syndromes. A thorough clinical assessment, coupled with the application of the Brighton Criteria, can aid in making an accurate diagnosis. Management of JHS poses significant challenges and typically involves symptomatic treatment, including physiotherapy, rehabilitation, and pharmacological therapy. Additionally, a multidisciplinary approach, including collaboration with different specialists, is vital. Further research is needed to improve our understanding of JHS and develop interventions based on solid evidence. However, with comprehensive management strategies, individuals with JHS can achieve better pain control and improved function, enabling them to lead more fulfilling lives.

Joint Hypermobility Syndrome: 2 Cases from the Capital of the Cherokee Nation and Review of Literature

Joint Hypermobility Syndrome (JHS) includes a spectrum of disorders that can be difficult to differentiate. Often overlapping or nonspecific symptoms can confound the diagnosis. The prevalence of JHS is much higher than the hypermobility variant of EDS (hEDS), although the latter is being diagnosed more especially with Brighton criteria that incorporate the Beighton score [1]. While other connective tissue disorders resulting in joint hypermobility may have specific genetic markers, the hEDS so far does not. This often requires clinicians to have a high index of suspicion for hEDS, or it may go undiagnosed, therefore leaving particularly young patients with a chronic debilitating disease without answers for their symptoms. Here we present two cases of JHS from the capital of the Cherokee Nation diagnosed relatively late compared to the average age at diagnosis.

Hypermobility: A Cause of Joint Pain in Children and Adolescents

Hypermobility: A Cause of Joint Pain in Children and Adolescents

Prevalence, injury rate and, symptom frequency in generalized joint laxity and joint hypermobility syndrome in a "healthy" college population.

Generalized joint hypermobility (GJH) and joint hypermobility syndrome (JHS) are gaining increased attention as potential sources of pain and injury. The aims of this study were to evaluate prevalence of GJH and JHS and to determine whether musculoskeletal injuries and symptoms commonly attributed to GJH and JHS were more common within a "healthy" college student population. The study involved a convenience sample of 267 college and graduate students, aged 17-26. GJH was assessed using the Beighton score with a cutoff of 5/9, while JHS was assessed using the Brighton criteria. Injury history and symptoms were assessed by recall. Prevalence of GJH was 26.2% overall (females 36.7%, males 13.7%). Prevalence of JHS was 19.5% overall (females 24.5%, males 13.7%). Injury rates were not significantly different for individuals who had GJH vs. those who did not have GJH. Individuals with JHS were significantly more likely to have had sprains, back pain, and stress fractures. Symptoms were no different between those with GJH and those who did not have GJH. However, individuals with JHS were significantly more likely to report clumsiness, easy bruising, and balance problems than those who did not have JHS. GJH and JHS were relatively common in this healthy college student population; GJH was not associated with increased incidence of injury or symptoms commonly attributed to JHS, but JHS was associated with increased incidence of some injuries and symptoms.

A study exploring the prevalence of Joint Hypermobility Syndrome in patients attending a Musculoskeletal Triage Clinic

© 2014 IOS Press and the authors. BACKGROUND: Generalised joint hypermobility (GJH) is common in the general population and may not confer any adverse symptoms. Joint Hypermobility Syndrome (JHS) is a connective tissue disorder that often runs in families and may present with a complex array of signs and symptoms. JHS is under-recognised and often poorly managed by the medical and physiotherapy professions. OBJECTIVES: The primary aim of this study was to investigate the prevalence of GJH and JHS in patients attending a Musculoskeletal Triage Clinic. Secondary aims of this study were to explore the health-related quality of life, pain levels, primary pain area and number of painful joints in patients with and without JHS. METHOD: A cross-sectional study design was used. The participant population included a convenience sample from patients attending a Musculoskeletal Triage Clinic based in a Primary Care setting in London. The main outcome tools were the Beighton Score, Brighton Criteria, the EQ-5D-5 L and the Visual Analogue Scale (VAS). RESULTS: A total of 150 participants were recruited into the study. GJH was recorded in 19% of participants and JHS was recorded in 30% of participants. Participants with JHS reported a greater number of painful joints (p < 0.05) than those without. No difference was found in the EQ-5D-5 L and the global VAS scores between the group with JHS and the group without. Participants with JHS (p < 0.01) were found to be more likely to present with wrist/hand pain as their main problem compared to those without JHS. CONCLUSIONS: This study found GJH in 19% and JHS in 30% of participants attending a Musculoskeletal Triage Clinic. This study also found that patients with JHS are likely to present with a greater number of painful joints and are more likely to present with wrist/hand pain as their main problem than those without JHS.

Hypermobility and joint hypermobility syndrome in Brazilian students and teachers of ballet dance.

The current literature has been discussing the risks and benefits of joint hypermobility (JHM) for careers in ballet This study aimed to evaluate the prevalence of JHM and joint hypermobility syndrome (JHS) in a group of ballet teachers and students, looking both at aspects related to the flexibility required to dance, as at the risk of injuries when hypermobility is associated with other symptoms, in the case of JHS. We evaluated ballet teachers and ballet students, with age ranging from 18 to 40 years. All participants completed identification and sociodemographic questionnaires and underwent a physical examination. JHM was assessed using the Beighton score with goniometry. Symptoms of JHS were evaluated according to the Brighton criteria. Final sample consisted of 77 participants, being 44 ballet students and 33 ballet teachers. The prevalence of JHM in the sample as a whole was 58 %. Teachers and students had no significant differences regarding the prevalence of JHM (p = 0.74) (OR 1.21; 95 % CI 0.48-3.07). However, the prevalence of JHS was significantly different (p = 0.04) between students (16 %) and teachers (36 %). Teachers were three times more likely than student to have JHS (OR 3.02; 95 % CI 1.03-8.85). Teachers and students also presented differences in the frequency of specific items of Beighton score and Brighton criteria. These data provide elements to discuss the relationship between hypermobility, ballet technique and selection for dance, suggesting that dancers with JHS could find in ballet teaching an alternative to maintain professional activity with dance, while remaining protected from the higher risk of injury that professional dancers may be exposed to.

Prevalence of Joint Hypermobility Syndrome Amongst Dental Students of the Medical University of Lublin

Abstract Introduction. The joint hypermobility syndrome is a connective tissue disorder affecting the entire organism. The symptoms include laxity of joint-stabilizing capsules and ligaments, excessive joint mobility and other accompanying symptoms. Some symptoms manifest in the oral cavity, which is of importance to dentists. Aim. The authors attempted to determine the prevalence of joint hypermobility syndrome in the population studied. Material and methods. The questionnaire study was conducted amongst students of the Faculty of Medicine with Dentistry Division, Medical University of Lublin. The study population consisted of 321 individuals, including 283 Polish students and 37 students of south-eastern nationalities (Saudi Arabia, Taiwan). Results and conclusions. The prevalence of constitutional hypermobility amongst dental students is comparable to that reported in literature. Constitutional hypermobility is more common in students of south-eastern nationalities than in Polish students.

PWE-160 The Joint Hypermobility Syndrome Is Associated With Functional Dyspepsia And Reflux And Identifies A Subgroup With Somatisation, Chronic Pain And Worse Quality Of Life

IntroductionThe Joint hypermobility syndrome (JHS) is a non-inflammatory connective tissue disorder with a prevalence of 20%. It is characterised by joint hypermobility,chronic pain, fibromyalgia (FM) and dysautonomia. Gastrointestinal (GI) symptoms...

Response to letter to editor regarding “visceral sensitization in postural tachycardia syndrome”

I thank Dr. Farmer, Dr. Fikree, and Dr. Aziz [1] for their thoughtful input. The authors propose abnormal gastric myoelectric activity as another form of visceral hypersensitivity. They believe that joint hypermobility syndrome (JHS) is an important confounding variable that should have been controlled for in our study. The authors cite data from various studies to support their contention. Seligman et al. [2] found enhanced variability of gastric myoelectric activity in PoTS patients and attributed gastrointestinal dysfunction to splanchnic hyperemia, anxiety, or abnormal connective tissue matrix in the gastrointestinal tract. Fikree et al. [3] used validated questionnaires in patients with JHS and gastrointestinal symptoms to conclude that this association may result from autonomic dysmotility and/or hypersensitivity factors. I concur with Dr. Farmer and co-authors that gastrointestinal symptoms in PoTS patients may be another possible manifestation of visceral hypersensitivity despite the fact that cited studies only allude to this issue. Regarding JHS and PoTS, Gazit et al. [4] found PoTS in 4 of 27 (15 %) JHS patients but did not demonstrate causeand-effect relationship specifically pertaining to PoTS. With the prevalence of JHS at about 20 % [3] and the heterogeneous nature of PoTS [5], we await definitive proof that JHS is a confounding variable in studies of visceral hypersensitivity in PoTS. The goal of our simple study was to use an objective correlate (heartbeat) of a disabling symptom (palpitation) to demonstrate visceral sensitization in PoTS and to provide a nidus for more sophisticated studies in this area.

Prevalence of joint hypermobility syndrome in Oman

The aim of this article is to document the prevalence of joint hypermobility and joint hypermobility syndrome (JHS) among young adults (aged 16–45 years) in a previously unstudied Middle Eastern population using observational and consecutive case studies. From 1 March to 1 April 2007, 222 young Omani men and women were interviewed at the Sohar Regional Hospital in Sohar, Oman, and examined for the five recognized features of hypermobility (i.e. laxity of the thumbs, little fingers, elbows, spine and knees) as well as 15 other musculoskeletal features. Approximately 45% of the study cohort had at least one lax joint, but only 4% possessed all five features of JHS and JHS could be diagnosed in only 6.3% of subjects. The women studied were older than the men (P<0.001), more overweight (P<0.05) and almost twice as likely to have JHS. A very high frequency (86%) of Marfanoid features was found among subjects with joint hypermobility. JHS in association with Marfanoid features appears to be a cause of musculoskeletal problems in Oman that is frequently unrecognized and may be almost twice as common in women than men.

Clinical study of hereditary disorders of connective tissues in a Chilean population

To demonstrate the high frequency and lack of diagnosis of joint hypermobility syndrome (JHS) and the seriousness of vascular Ehlers-Danlos syndrome (VEDS). Two hundred forty-nine Chilean patients with hereditary disorders of the connective tissues (CTDs) and 64 control subjects were evaluated for the diagnoses of JHS and VEDS using the validated Brighton criteria, as compared with the traditional Beighton score. In addition, the presence of blue sclera was determined, with the degree of intensity graded as mild, moderate, or marked. The frequency of hereditary CTDs was 35%, with diagnoses of JHS in 92.4% of subjects, VEDS in 7.2%, and osteogenesis imperfecta in 0.4%. The Beighton score proved to be insufficient for the diagnosis of JHS (35% of subjects had a negative score), whereas the Brighton criteria yielded positive findings (a diagnosis of JHS) in 39% of control subjects. Blue sclera was frequent, being identified in 97% of JHS patients and 94% of VEDS patients. Moderate osteopenia/osteoporosis was observed in 50% of patients with VEDS and 26% of those with JHS. Dysautonomia, dyslipidemia, and scoliosis were more frequent in VEDS patients than in JHS patients. The typical JHS facial appearance and the "hand holding the head sign" were identified. Raynaud's phenomenon was extremely rare in JHS patients (2%). Ruptured uterus and cerebral aneurysm occurred in 12% and 6% of VEDS patients, respectively. Spontaneous pneumothorax was more frequent in VEDS patients (11%) than in JHS patients (0.9%). JHS is very frequent but usually undiagnosed. The Beighton score is an insufficient method for JHS diagnosis. We recommend that physicians learn to recognize the typical facial features of JHS and be able to identify blue sclera. We also propose that validated hypermobility criteria be routinely used. Further research is needed to determine why the prevalence of JHS is so high in Chile.

Joint hypermobility syndrome and mitral valve prolapse in panic disorder

Objective: The purpose of this study is to test the association between joint hypermobility syndrome (JHS) and panic disorder (PD) and to determine whether mitral valve prolapse (MVP) modifies or accounts in part for the association. Method: A total of 115 subjects are included in this study in three groups. Group I ( n=42): panic disorder patients with MVP. Group II ( n=35): panic disorder patients without mitral valve prolapse. Group III ( n=38): control subjects who had mitral valve prolapse without any psychiatric illness. Beighton criteria were used to assess joint hypermobility syndrome. Two-dimensional and M-mode echocardiography was performed on each subject to detect mitral valve prolapse. Results: Joint hypermobility syndrome was found in 59.5% of panic disorder patients with mitral valve prolapse, in 42.9% of patients without mitral valve prolapse and in 52.6% of control subjects. Beighton scores was 4.93±2.97 in group I, 4.09±2.33 in group II, and 4.08±2.34 in group III. There was no significant difference between groups according to Beighton scores. Conclusion: We did not detect a statistically significant relationship between panic disorder and joint hypermobility syndrome. Mitral valve prolapse and joint hypermobility syndrome are known to be etiologically related and we suggest that mitral valve prolapse affects the prevalence of joint hypermobility syndrome in the panic disorder patients.

Joint hypermobility syndrome among undergraduate students.

To assess the prevalence of joint hypermobility syndrome among undergraduate students of the University of Port Harcourt, Nigeria using the Beighton's criteria. Cross- sectional prospective study of 550 randomly selected undergraduate students. Departments of Anatomy and Human Physiology, College of Health Sciences, University of Port Harcourt, Nigeria. The overall prevalence, and the male/female prevalence of joint hypermobility syndrome. Five hundred and fifty subjects (250 males and 300 females) were assessed. Seventy one (12.91%) subjects consisting of 20 (8.0%) males and 51 ( 17.0%) females, had features of joint hypermobility syndrome, suggesting a higher female prevalence. Knee joint, back and wrist joint pains, in descending order were found to be the commonest type of joint complaints. The study indicates that joint hypermobility syndrome is not rare in Nigerians and suggests that it should attract the attention of Nigerian medical practitioners.