Prevalence Of Iron Deficiency Anemia Research Articles

Is Iron Deficiency Anemia still Becoming Community Health Problem in Urban Area?

Background: Iron deficiency anemia is one of the common public health problems that found in various countries, including Indonesia. The incidence of iron deficiency anemia does not only occur in rural areas but also in urban areas. Iron deficiency that occurs in adolescent girls with or without anemia has a negative impact on immune function, growth and physical and mental development. Purpose: To determine the incidence of anemia in adolescent girls in urban areas. Patients and methods: This study was an observational study with a cross sectional design. The research subjects were 52 young women aged 15-25 years living in the city of Semarang, Central Java. The subject will be taken a blood sample to check the complete blood profile and iron status, namely serum ferritin, serum iron, and serum TIBC (total iron binding capacity). Research data analysis was carried out using a computer program. Results: The prevalence of iron deficiency anemia among female adolescents in urban areas in this study was 13.4% while adolescent girls who experienced iron deficiency without anemia were 13.4%. Conclusion: Iron deficiency anemia can occur in urban areas with a prevalence > 5%.

Iron deficiency in peri-menopausal women: Clinical considerations from an expert consensus

Iron deficiency (ID) and iron deficiency anaemia (IDA) are usually anticipated to occur during and after pregnancy. Peri-menopausal women are at risk of ID/IDA & warrant attention as the symptoms of ID can be misinterpreted or overlooked. Scientific literatures convey iron deficiency to be considered as a major health problem for perimenopausal women. However, Indian evidence on ‘Iron deficiency in peri-menopausal women’ is scarce.The aim of this article is to understand the impact of iron deficiency on health of peri-menopausal women in India and to understand its important clinical considerations. Developing an expert consensus towards diagnosis & management of iron deficiency and iron deficiency anaemia in this population is the need of the hour.A 3-step modified Delphi method was used to build up the consensus. Nine experts representing gynaecology and endocrinology were invited to participate in the panel discussion. Session was being moderated by a senior gynaecologist. In round 1 – the prevalence of iron deficiency anemia in perimenopausal women and risk factors of iron deficiency anemia were discussed. The panel members asked polling questions and each member’s response to the poll question was recorded. The same voting method was used in round 2 and 3, which discussed the diagnosis and management, respectively. In round 1, round 2 and round 3 statements reached consensus. Consensus was attained for eleven statements representing four different domains: prevalence, risk factors, diagnosis, and treatment. This consensus guideline will help to standardize care, provide guidance on screening and treatment of iron deficiency anemia in perimenopausal women. This will also assist in clinical decision-making for all healthcare professionals.

Study of Prevalence of Iron Deficiency Anemia in Hospitalised Children in Tertiary Care Centre

Abstract Background: Anemia prevalence in young children continues to remain over 70% in most parts of India and Asia. In developing countries like India,anemia is a significant cause of mortality and morbidity in children under 5 years of age. In public health terms, Iron deficiency anemia (IDA) is a very important causative factor for childhood anemia. Materials & Methods: A prospective observational study was conducted on hospitalized children in tertiary care center. All children between 1 month to 18 years of age were admitted in Pediatric ward were taken to the study for 1.5 years study period. Results: Total number patients admitted in pediatric ward were 1280 out of which 812 were enrolled for the study, out of which 522 patients have been studied in detail as they had iron deficiency anemia. The total prevalence in our study period is 65.64%. Our analysis showed that males outnumbered females with sex ratio of Male: Female is1.76:1. This study shows that the children of 1 month to 5 years is 361 which are 69.1%, children of age 5-12years are 123 which is 23.6%, children of age 12-18years are 38 which is 7.3%. We observed that the most common age group involved is less than 5 years which is significant. The etiology of the hospitalization has been studied, out of which Lower respiratory infections were more common. Conclusion: This study revealed that the prevalence of IDA in under 5 years is more common than in other age groups. Children with anemia and those with iron deficiency anemia were found to be more susceptible to lower respiratory tract infections.

Prevalence of iron deficiency anemia in patients with metastatic colorectal cancer

Background: Iron has dual properties: it may promote both tumor growth and cell apoptosis. Compared to healthy cells, cancer cells are more dependent on the iron levels. Ferroptosis can be triggered directly in cancer cells, which would result in their self-destruction. Identification of iron balance abnormalities and their correction could impact the effects of specific treatments in cancer patients.
 Aim: To assess the prevalence of iron deficiency in patients with metastatic colorectal cancer (mCRC) and to identify an association of low serum iron levels with clinical and morphological characteristics of the disease.
 Materials and methods: The study included 69 treatment-nave patients with mCRC. Iron deficiency was defined as low serum iron levels before the initiation of any specific therapy: serum iron concentration 10.7 mcmol/L in men and 9.0 mcmol/L in women.
 Results: The mean age of the mCRC patients was 61.1 years (range, 28 to 83 years), 35/69 (50.7%) were men. The bigger proportion of the tumors was left-sided (62.3%). In 48.3% of the patients, the disease was diagnosed at the metastatic stage. The most frequent locations of metastasis were liver (41.3%) and lungs (32.1%). 55.1% (38/69) of the patients had undergone a non-radical resection or primary curative surgery. KRAS mutations were found in 37.7% of the patients. Low serum iron levels were found in 53.6% (37/69) of the total sample of the mCRC patients and in 72.4% (19/38) of the patients with a non-resected primary tumor (p = 0.05).
 Conclusion: Irrespective on the clinical and morphological characteristics, the majority of patients with metastatic colorectal cancer have iron deficiency anemia before the initiation of specific anti-tumor therapy.

Comparison of Efficacy and Tolerability of Ferrous Sulfate and Carbonyl Iron in Iron Deficiency Anemia in Pregnant Woman

Introduction: Iron deficiency anemia in pregnancy is common and causes a huge burden globally. Bangladesh is known to have a high prevalence of iron deficiency anemia in pregnant women. Hence, it is important to evaluate the efficacy and tolerability of drugs in treatment of iron deficiency anemia in pregnancy.
 Objective: The purpose of present study was to compare the efficacy and tolerability of Ferrous Sulfate and Carbonyl Iron in Iron Deficiency Anemia in pregnant women.
 Methodology: An observational prospective study was conducted in obstetric and gynae out – patient department of Sir Salimullah Medical College and Mitford Hospital. Woman between 16 – 28 weeks of pregnancy with haemoglobin level 7 – 10 g/dl with microcytic hypochromic blood film were included in this study. Pregnant women in 1st and 3rd trimester of pregnancy were excluded from the study. Among the study population one group was given Tablet Ferrous Sulfate and another group was given Capsule Carbonyl Iron.
 Results: There was significant and comparable rise in HB in 4th, 8th and 12th week in the two group. (p<0.001). Carbonyl iron showed significantly more rise in Hb as compared to Ferrous Sulfate. Adverse effects were seen more in number and intensity with Ferrous Sulfate. Individual efficacy of both compounds was good but Carbonyl Iron was better tolerated.
 Conclusion: Carbonyl Iron is more effective and tolerable than Ferrous Sulfate in treatment of iron deficiency anemia in pregnancy.
 Sir Salimullah Med Coll J 2022; 30: 83-88

Anemia in Pregnancy: A knowledge, Attitude and Practice Survey Amongst Obstetricians and Gynaecologists in India.

Anemia continues to affect one-third of the global population and is one of the most common reasons for large-scale morbidity and mortality especially among women. The importance of iron-rich diet has always been the backbone of preventing iron deficiency anemia (IDA) in vulnerable age groups followed by oral iron therapy and parenteral iron therapy as the next options in management of iron deficiency. Objective of this survey was to assess the knowledge, attitude and practices of obstetricians and gynaecologists relevant to anemia in pregnancy and identify the practice gaps in management of anemia in pregnancy. This was a knowledge, attitude and practice (KAP) survey involving obstetricians and gynaecologists (ObGyns) across India. A validated questionnaire of twenty questions was used to assess knowledge, attitude and practice about anemia and its management. Results were expressed as percentages. 1974 ObGyns participated in the survey. 88.7% ObGyns screen anemia in first trimester, 53.7% ObGyns perform CBC along with RBC indices. Majority of ObGyns estimate Hb thrice during antenatal period. 50% ObGyns do not consider thalassemia screening routinely and deworming regularly. 92.4% ObGyns believe that iron supplementation is required even if Hb > 11g/dL. Majority of them prefer low-dose iron therapy, 59.9% prefer to use 100mg oral iron daily. Almost half of ObGyns prefer to change iron salt when patients do not respond, instead of escalating to injectable iron. Interestingly 52% ObGyns evaluate serum ferritin before starting intravenous iron therapy. 43.5% perform Hb estimation as early as 2weeks after IV iron therapy. Majority (82.2%) of ObGyns prefer blood transfusion as a treatment of choice when Hb < 5g/dl at 34weeks gestation. Only 40.5% of participants are aware of the exact cut-off for diagnosing postpartum anemia. Majority of the ObGyns are aware of the iron prophylaxis in postpartum period till 3-6months. More than 90% ObGyns consider intravenous iron for severe anemia of postpartum period. The present KAP survey highlights the observation, perception and the practicing behaviour of obstetricians and gynaecologists on anemia in pregnancy and identifies practice gaps in anemia management.

Fortification of salt with iron and iodine versus fortification of salt with iodine alone for improving iron and iodine status.

Fortification of salt with iron and iodine versus fortification of salt with iodine alone for improving iron and iodine status.

A Cross-sectional Study of Iron Deficiency Anemia and Hemoglobinopathy Carriers among School Children in Two Different Cities in KSA

Aim: Iron deficiency anemia (IDA) is the most common cause of anemia in the Kingdom of Saudi Arabia. Thalassemia and sickle cell disease (SCD) are major concerns in several nations, including KSA. This study sought to investigate the prevalence of IDA, sickle cell trait (SCT), and B thalassemia trait (BTT) among school children in Al-Khobar and Makkah, Saudi Arabia.&#x0D; Methods: A multistage random sample of 570 school children aged 12–18 years from both cities were educated about these illnesses and tested for CBC, serum iron, TIBC, reticulocytosis, and sickling. In some circumstances, hemoglobin electrophoresis and HPLC were used.&#x0D; Results: Overall, 13% of people had IDA, 3.2 percent had SCT, and 2.5 percent had BTT. The hematological parameters of students with IDA and BTT differed significantly from those of normal students in each city, but not between normal students and those with SCT. There were no significant differences between the sexes for all blood parameters except iron and TIBC.&#x0D; Conclusion: Strengthening public health education, dietary initiatives, and school-based hemoglobinopathy carrier screening is proposed to help detect anemia early.

Prevalence of iron deficiency anaemia in tuberculosis

Introduction: In India, Tuberculosis is endemic disease with more than 90% of population are in latent infection. In this study we measure the prevalence of iron deficiency anaemia in newly diagnosed TB cases. Methodology: An Observational cross-sectional study was conducted at Respiratory Medicine, MIMS, Nellimarla, Vizianagaram District, and Andhra Pradesh State from July 2020 to June 2021. Inclusion criteria were newly diagnosed TB patients of age &gt;18 years. Exclusion criteria were Immunocompromised, Pregnancy, Patients with malignancy, Patients with past history of TB and who are receiving ATT Unwilling to participate. Results: During the one year study period, a total of 50 patients were included. 32 were male and 18 were female. The study showed decrease in Iron, Hemoglobin, Transferrin and Transferrin saturation and increase in TIBC and Ferritin levels. They are many available methods for assessing anaemia at primary care level and to treat or iron prophylactic supplementation. Conclusion: In the present study, it was concluded that iron metabolism was altered in pulmonary tuberculosis. A low serum iron, transferrin and transferrin saturation with increase in ferritin and TIBC.

Iron Deficiency Anemia: An Overlooked Complication of Crohn's Disease.

BackgroundThere are few studies to evaluate the association between iron deficiency anemia (IDA) and Crohn’s disease (CD). We examined this association in a USA-based cohort of patients with CD.MethodsWe queried the Nationwide Readmission Databases 2018 using the International Classification of Disease, 10th Revision, and Clinical Modification (ICD-10-CM) codes to identify all adult patients admitted with a diagnosis of CD. Primary outcomes were the prevalence of IDA among patients with CD. Secondary outcomes included inpatient mortality, the length of stay, all-cause 30-day non-elective readmission rate, and total cost of hospitalization. Multivariate regression analysis was performed to study the impact of IDA on inpatient mortality and non-elective readmissions.ResultsOf the 72,076 patients discharged from an index hospitalization for CD, 8.1% had IDA. CD patients with IDA had increased length of stays in days (4, interquartile range (IQR): 2 - 6 vs. 3, IQR: 2 - 5; P < 0.001), increased median total charges ($35,160, IQR: $19,786 - $64,126 vs. $31,299, IQR: $17,226 - $59,561; P < 0.001), and were more common to require blood transfusion during hospitalization (13.6% vs. 3.4%, P < 0.001) compared to CD patients without IDA, respectively. IDA was independently associated with increased odds of all-cause 30-day non-elective readmission (odds ratio (OR): 1.254, 95% confidence interval (CI): 1.154 - 1.363, P < 0.001) and increased odds of all-cause 90-day non-elective readmission (OR: 1.396, 95% CI: 1.302 - 1.498, P < 0.001).ConclusionsIn a large nationwide cohort of patients hospitalized for CD, we observed a significant burden of IDA. Additionally, we found a significant association between IDA and worse hospitalization outcomes.

Iron Deficiency Anemia: Cause, Plant Based Iron, Fortification and Impact on Lifestyle and Socioeconomic Parameters

Micronutrient deficiency is prevelant in both high income and low-income countries globally causing major health issues, especially iron deficiency which causes hypoproliferative microcytic anemia. Iron deficieny anemiais effecting more than two billion population on earth especially pregnant woman, infants and woman of reproductive. Iron plays a key role in the formation of red blood cells and reactions occurring in the human body. Food is one of the best and safe options to prevent and cure iron deficiency anemia. In the present study, we highlighted different foods with special reference to plant-based foods for the treatment and prevention of iron deficiency anemia. Literature revealed that major cereal flours, cumin seeds, green leafy vegetables, moringa leaves, papaya with supplements, beet root, apples, pomegranate, bael, sugar molasses and berries are best sources of iron due to presence of ascorbic acid. Prebiotics and probiotics fortification can also increase the iron absorption in the gut by providing optimum pH for absorption. In addition to change in dietary patterns, fortification of major crops, flours and salt should be made mandatory by as in many countries. Moreover, Iron fortified formulas, complementary food, beverages, baked items (cookies) and confectionary are best ways to prevent and cure iron deficiency anemia in children and adults. Similarly, sugar molasses from sugar industry is one of the superabundant sources of iron which can be used as supplement for value addition. However, human research is required to check the efficacy of fortified products to prevent iron deficiency anemia in future generations.

A Retrospective Study Using Mentzer Index for Prevalence of Iron Deficiency Anemia among Infants Visiting Maternal Centers at the Age of One Year.

Anemia, defined as a hemoglobin level two standard deviations below the mean for age, is prevalent in infants and children worldwide. Characterizing anemia as microcytic and normocytic depends on the mean corpuscular volume (MCV), which is an important parameter in differentiating many types of anemia. Microcytic anemia due to iron deficiency is the most common type of anemia in children. In this study, we aimed to assess the Mentzer index used by the Ministry of Health (MOH) in Palestine as a useful tool in differentiating between iron deficiency anemia (IDA) and thalassemia. We assessed for the prevalence of IDA among infants at the age of one year visiting the mother centers from seven West Bank provinces in Palestine. Medical records and hematology laboratory data of 3262 infants were retrospectively analyzed from the years of 2018 to 2020. The Mentzer index applied to all population by dividing mean corpuscular volume (MCV, in fL) by the red blood cell count (RBC, in millions per microliter). A corrected Mentzer index was further calculated among anemic infants to include only microcytic (MCV with less than 72 fl) and hypochromic (mean corpuscular hemoglobin concentration (MCHC) with less than 32 g/L) indices. Mentzer index calculations for the whole population showed that 29.1% were anemic (hemoglobin (HGB) less than 11 g/dl): 21.1% had mild anemia, 7.6% had moderate anemia, while 0.2% had severe anemia. The corrected Mentzer index calculations showed a prevalence of 5.9% and 3.2% among IDA and thalassemia infants, respectively. Severity of anemia was correlated with low body weight and infants born through cesarean mother birth with no interference with gender influence. CBC indices of RBC count, HGB, MCV, and mean corpuscular hemoglobin (MCH) showed a significant difference (p values < 0.05) between IDA and thalassemia infants' populations following the corrected Mentzer index. With the corrected Mentzer index, we introduced a new CBC index among infants at the age of 1 year in Palestine. These lab references could aid in differentiating IDA and thalassemia among the population and improve initial diagnosis screenings. The Mentzer index calculation for the whole population did not necessarily include cases of IDA, and therefore, it is recommended to comprise microcytic and hypochromic anemia indices prior to performing the Mentzer index.

The Association between Helicobacter Pylori Infection and Iron Deficiency Anemia in Children: A Systematic Review and Meta-Analysis

Abstract Objectives This study, comprising a systematic review and meta-analysis, was conducted to assess the association between Helicobacter pylori infection and the risk of iron deficiency anemia (IDA) in children. Methods We followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Relevant published studies were searched in the databases. Retrieved studies were assessed for quality using the Modified Newcastle-Ottawa Scale for quality assessment. The “meta” package of statistical software “R 4.0.3 was used for statistical analysis. Results Overall, 22 eligible studies (eight cross-sectional, six randomized control trials, five case-control, two surveys, and one cohort), including nine (40.9%) from Asia, four (18.1%) from America, four (18.1%) from Africa, four (18.1%) from Europe, and one (4.5%) from Australia with a total of 3,434 cases and 4,455 controls were included in this systematic review and meta-analysis. We found that H. pylori infection was associated with a high risk of IDA (odds ratio 1.70, 95% confidence interval 1.21 − 2.38) in a random-effects model. Meta-regression analysis showed that none of the investigated factors that may affect the prevalence of IDA reached statistical significance. There was statistically significant difference between results when studies were categorized according to the methods used to diagnose H. pylori and level of incomes based on World Bank classification. The GRADEpro Guideline Development Tool evidence for the risk of IDA was of a “moderate certainty.” Conclusions This meta-analysis with a “moderate certainty” of evidence showed an association between H. pylori infection and a high risk of developing IDA in children.

Iron from nanostructured ferric phosphate: absorption and biodistribution in mice and bioavailability in iron deficient anemic women

Food fortification with iron nanoparticles (NPs) could help prevent iron deficiency anemia, but the absorption pathway and biodistribution of iron-NPs and their bioavailability in humans is unclear. Dietary non-heme iron is physiologically absorbed via the divalent metal transporter-1 (DMT1) pathway. Using radio- iron isotope labelling in mice with a partial knockdown of intestine-specific DMT1, we assessed oral absorption and tissue biodistribution of nanostructured ferric phosphate (FePO4-NP; specific surface area [SSA] 98 m2g-1) compared to to ferrous sulfate (FeSO4), the reference compound. We show that absorption of iron from FePO4-NP appears to be largely DMT1 dependent and that its biodistribution after absorption is similar to that from FeSO4, without abnormal deposition of iron in the reticuloendothelial system. Furthermore, we demonstrate high bioavailability from iron NPs in iron deficient anemic women in a randomized, cross-over study using stable-isotope labelling: absorption and subsequent erythrocyte iron utilization from two 57Fe-labeled FePO4-NP with SSAs of 98 m2g−1 and 188 m2g−1 was 2.8-fold and 5.4-fold higher than from bulk FePO4 with an SSA of 25 m2g−1 (P < 0.001) when added to a rice and vegetable meal consumed by iron deficient anemic women. The FePO4-NP 188 m2g-1 achieved 72% relative bioavailability compared to FeSO4. These data suggest FePO4-NPs may be useful for nutritional applications.

Pencegahan Anemia Defisiensi Besi pada Remaja melalui Penyuluhan Gizi Seimbang

Adolescence is the second critical period for physical growth after the first year of life. Indonesia is home to about45 million adolescent boys and girls or equivalent to 18% of the total population. Indonesia suffers from a fairly high nutritional deficiency accompanied by an increasing prevalence of obesity – which is known as the Double Burden of Nutrition Problems. During adolescence, there are specific biological and physiological changes in the body according to gender so that nutritional needs become different. Adolescents are increasingly considered important as potential agents of nutritional change in Indonesia because they play a role in cutting the intergenerational chain of poverty and malnutrition. The Tanjung Muhammadiyah Women's Orphanage is one of the private institutions that manages and protects young orphaned and orphaned girls. In the orphanage there are about 34 young women who attend school from elementary school to high school. Every day the children in this orphanage get food rations from the orphanage's kitchen with a standard menu. Temporary data obtained that most of the teenagers in this orphanage suffer from mild anemia, one of the possible causes is a lack of knowledge about balanced nutrition. The purpose of providing counseling to adolescents in this orphanage is to provide knowledge and understanding of nutritional needs and fulfillment, especially for young women as an effort to prevent iron deficiency anemia in adolescents

Prevalence of iron deficiency anemia in Brazilian women of childbearing age: a systematic review with meta-analysis.

BackgroundIron deficiency anemia (IDA) is among the most common micronutrient deficiencies in women of childbearing age and may affect children’s development. Brazil has several national programs to tackle this condition, such as food fortification and supplementation for pregnant women, but IDA prevalence in this population has not been systematically reviewed. We sought to determine the prevalence of IDA in Brazilian women of childbearing age through a systematic review with metanalysis.MethodologyA protocol was previously published on the PROSPERO platform under the code CRD42020200960. A panel of the National Council for Scientific and Technological Development (CNPq) approved the protocol of this study under the public call number 26/2019. The main databases searched were MEDLINE, Web of Science, Scopus, Lilacs, and SciELO. In gray literature, the Brazilian Digital Library of Theses and Dissertations and the annals of the Brazilian Congress of Epidemiology and the Brazilian Congress of Public Health were accessed. The search strategy involved terms related to the condition (IDA) and the age group of the population of interest (teenagers and adults). Studies that had assessed the prevalence of IDA in Brazilian women of childbearing age (10–49 years) were included. Three independent reviewers read all titles and abstracts and extracted data from the included studies. Random effects meta-analyses using the Freeman-Tukey arcsine transformation were carried out with prevalence data, and meta-regression was conducted to test for subgroup differences. The quality of the studies was assessed using the Newcastle-Ottawa Scale.ResultsFrom 21,210 unique records screened, 237 full-texts were retrieved, of which 91 were included in the qualitative synthesis, and 83 were included in the meta-analysis. The overall IDA prevalence was 25% (95% CI [23–28], 83 studies). The subgroup of studies that used random sampling showed a prevalence of 22% (95% CI [17–27], 22 studies), whereas in those with non-random sampling, the prevalence was 27% (95% CI [23–30], 61 studies), without significant differences between subgroups in the metaregression (P = 0.13). High prevalence of IDA were found in the subgroups of studies conducted in the North and Northeast regions (30%; 95% CI [24–37]; seven studies, and 30%; 95% CI [26–34]; 27 studies, respectively), in studies conducted with indigenous population (53%; 95% CI [27–78], four studies), and with studies that had their collections after 2015 (28%; 95% CI [23–34], nine studies).ConclusionsIDA in women of childbearing age remains a public health problem in Brazil, especially in the North and Northeast region. The national programs should be strengthened and more thoroughly supervised to decrease this condition nationally.

Iron Fortification through Universal Distribution of Double-Fortified Salt Can Increase Wages and Be Cost-Effective: An Ex-Ante Modeling Study in India

BackgroundThe alleviation of iron deficiency through iron supplementation has not effectively reduced anemia in India, mainly due to low compliance. Food fortification with iron is considered a viable alternative, and the provision of double-fortified salt (DFS; with iron and iodine) has been mandated in public health programs. Limited evidence exists on its benefit–cost ratio. ObjectiveIn this study we sought to estimate the economic benefit in terms of increased wages in relation to introduction of DFS in reduction of anemia and the cost of doing so. MethodsThe economic benefit of introducing DFS in India was derived using a series of mathematical, statistical, and econometric models using data from national surveys capturing earnings and dietary iron intake of the population. Anemia status was predicted from data on dietary intake, sanitation, and for women, menstrual losses. The impact of iron deficiency anemia (IDA) on wages was estimated using a Heckman Selection model and 2-stage least squares procedure. Benefit of DFS was estimated through increased wages attributed to anemia reduction compared with its cost. ResultsMen and women with IDA had lower wages (by 25.9%, 95% CI: 11.3, 38.1; and by 3.9%, 95% CI: 0.0, 7.7, respectively) than those without IDA. Additional iron intake through DFS was predicted to reduce prevalence of IDA (from 10.6% to 0.7% in men and 23.8% to 20.9% in women). The economic benefit–cost ratio of introducing DFS at a national level was estimated to be 4.2:1. ConclusionsIron fortification delivered through DFS under a universal program can improve wages and be sufficiently cost-effective for its implementation at scale in India.

A COMPARATIVE STUDY OF PREVALENCE OF ANEMIA AND ITS RISK FACTORS AMONG SCHOOL-GOING ADOLESCENT GIRLS IN THE FIELD PRACTICE AREAS OF MEDICAL COLLEGE IN GAUTAM BUDDHA NAGAR DISTRICT

Objectives: (1) The study was to determine the prevalence of iron deficiency anemia among adolescent girls in the field practice areas of a medical college of GautamBuddha Nagar district and (2) to assess the risk factors associated with iron deficiency anemia among adolescent girls in the field practice areas of a medical college of GautamBuddha Nagar district. Methods: A school-based cross-sectional study was conducted to assess the prevalence of anemia among adolescent girls of the field practice areas of the medical college of Gautam Buddha Nagar District. The sample size came out to be 236. One school each from RHTC and UHTC was selected randomly, and all adolescent girls were enrolled in the study. Results: The present study was conducted on 684 adolescent females (251 from RHTC and 433 from UHTC) in our study period of 3 months. The prevalence of anemia in the whole population was 42%, 54.5% among rural and 35.5% of adolescents in urban area were found to be anemic at the time of the study. The factors that were found to be significantly associated with adolescent anemia were age of onset of menarche, history of albendazole intake, residing in joint family, and lower socioeconomic status. Conclusion: The prevalence was high among girls who were above 16 years of age and girls who belonged to lower socio-economic groups and belonging to rural area. There is a need for a regular supply of iron and folic acid tablets and for improving medication adherence regarding consuming these tablets among adolescent girls and also about the dietary advice.

Prevalence and Associated Risk Factors of Iron Deficiency Anemia Among School Teenagers in Mbouda, Western Cameroon: A Cross Sectional Study

Teenagers are a particularly vulnerable age group to Iron Deficiency Anemia (IDA). This study aimed to determine the prevalence and associated risks factors of IDA among apparently healthy school teenagers in Mbouda, West-Cameroon. Blood samples, up to 778 were randomly collected from adolescents aged 10-19 years of four schools in Mbouda. For this cross-sectional study, participants collaborated to fill a questionnaire with us on socio-economic and demographic status. The methods of 24 hours recall, and dietary history were used to determine the dietary habits, the type of food and the consumed meal frequencies during a day. Appropriate indicators including hemoglobin and hematocrit, serum iron, ferritin, transferrin, and total iron binding capacity, transferrin saturation were determined using standard methods. Our findings showed that the prevalence of IDA was 82.4 % and 17.64 % in participants aged 13-19 years and 10-12 years respectively. High significant difference in the mean values of Serum Iron (p = 0.001), Serum ferritin (p&lt;0.001), TIBC (p&lt;0.001), CST (0.001) and Hemoglobin (p&lt;0.001, CI = 2) were observed in participants without IDA compared to those with IDA. The sociodemographic risk factors of IDA in school adolescents were sex [P = 0.001, OR = 0.39 (0.22–0.69)], residence areas [P = 0.001, OR = 3.30 (1.55–7.02)] and school sites [P = 0.002]. Consumption of vegetable [OR: 0.30 (0.17–0.54)], fruits, [OR: 0.26 (0.12–0.52)] and fats [OR: 0.33 (0.12–0.91)] significantly decreased the risk of IDA (p &lt;0.05), whereas the consumption of legumes [OR: 2.60 (1.57–4.32)] significantly increased the risk of IDA. This study suggested that IDA could be prevented by providing proper knowledge on the healthful diet including fats animal food sources, fruit and vegetables, improved lifestyle, and on the harmful effects of IDA to the teenager’s productivity.

Impact of iron deficiency anemia on quality of life in patients with ulcerative colitis

AbstractAdvances in the last two decades have resulted in better long‐term remissions in patients with ulcerative colitis (UC), which is defined as an idiopathic, chronic inflammatory disorder of the colonic mucosa. This better remission has not transformed into a better quality of life. Almost one‐third of these patients have mild to moderate anemia, which is one of the main factors leading to decreased quality of life; hence we aimed to determine the prevalence of iron deficiency anemia (IDA) in UC during remission and its impact on the quality of life in this subpopulation. In this prospective study, all consecutive patients of UC in remission for the last 3 months were evaluated for disease activity by Simple Clinical Colitis Activity Index (SCCAI), IDA by blood parameters and quality of life by Short Inflammatory Bowel Disease Questionnaire (SIBDQ). All patients with proven IDA were given oral iron supplements (Ferrous Ascorbate elemental iron 100 mg) for 3 months. Blood parameters, SCCAI, and SIBDQ scores were evaluated at the end of therapy to compare them before iron supplementation. Out of 125 patients of UC seen during the study period, 69 were in remission. IDA was seen in 34 patients (49.27%). Median pre‐intervention and postintervention quality of life scores—SIBDQ (4.9 [4.2‐5.8] vs 5.4 [5.0‐6.1]) and blood parameters [hemoglobin 10.7 (9.8‐11.4) g% vs 13.2 (12.8‐13.7) g%]—showed significant improvement after iron supplementation. Prevalence of IDA in UC during remission is common (49.27%). Oral iron supplementation improves the quality of life and anemia significantly without increasing disease activity in UC under remission.