Prevalence Of Health Disorders Research Articles

Are there subgroup differences in the accuracy of 'screening' questions for mood and anxiety disorder diagnostic interviews?

To examine the impact of potential measurement bias (i.e., differential item functioning [DIF]) across sex, age, employment, location, and substance use disorders on the screening properties of epidemiological surveys that utilise screening questions when estimating prevalence of mood and anxiety disorders. Data comprised of 15,893 respondents who completed the 2020-2022 Australian National Survey of Mental Health and Wellbeing. Questions from the screening module of the Composite International Diagnostic Interview 3.0 were analysed using confirmatory factor analysis and DIF across subgroups of interest. Sensitivity, specificity, and classification rate were derived and compared across models that did and did not adjust for significant levels of DIF. Sources of DIF were identified across the items was due to age and sex at birth with relatively fewer items displaying DIF across employment, location, and substance use disorders. In terms of screening, the absolute differences in sensitivity and specificity between the DIF-free and DIF models ranged from 0.001 to 0.091. The current study found some evidence of DIF in the screening questions used to evaluate mental health disorder prevalence. However, the overall influence of DIF on screening into at least one mood and anxiety disorder module was found to be minimal.

Past-year mental health issues: discrepant survey & administrative data

Abstract Introduction Accurately measuring mental health disorder prevalence is crucial for public health planning. Administrative and survey data are common methods, but often yield differing results. This study compares case identification of mental health issues across these data sources in Slovenia. Methods We linked the 2019 European Health Interview Survey (EHIS) with three Slovenian health administrative databases: the National Hospital Health Care Statistics Database, Outpatient Prescription Drugs Database, and Absence From Work Database. Case identification utilized self-report of any mental health issue in the past 12 months and healthcare utilization records in 12 months preceding participation in EHIS. Multinomial logistic regression was used to examine the association between socio-demographic factors and case identification across data sources. Results Significant differences were found in 12 month prevalence of any mental health issue estimates between data sources. Only 45.9% of self-reported cases were identified in administrative data, and 36.6% of administrative cases self-reported mental health issues (Kappa = 0.302). Socio-demographics, including age, gender, education, and employment status, were significantly associated with the likelihood of identification in specific data sources. Discussion Our findings underscore the importance of data source and assessment tool selection on mental health prevalence estimates. Variations in identification across population subgroups could reflect differences in healthcare access and self-disclosure biases. Linking data sources and considering their inherent limitations is crucial for accurate burden estimation. Key messages • Data source and assessment methods significantly impact how we identify individuals with mental health issues in the past year. • Combining data sources and understanding their limitations is essential for improving mental health burden estimation.

Canadian Provincial and Territorial Correctional Worker Mental Health and Well-Being Study (CWMH): Navigating Practical and Unanticipated Methodological Challenges

Previous research assessing correctional worker (CW) mental health has seldom assessed for differences based on jurisdiction or diverse occupational categories. The current study was designed to provide a nuanced quantitative examination of mental health disorder prevalence and related problems among CWs and to qualitatively explore the varying social contexts surrounding CW well-being. We reflect on how we overcame unanticipated challenges and disruptions (e.g., technology, COVID-19 pandemic) throughout the design, launch, and analysis of the survey, and illustrate how our national study, driven by a rigorous methodological approach and collaborative research design, builds on the extant CW mental health and wellness literature.

Self-reported prevalence of sleep and mental health disorders in current and former athletes: a preliminary cross-sectional investigation of help-seeking behaviours

ABSTRACT Objective Athletes typically report a high prevalence of mental health issues and face significant barriers within the sporting environment that prevent help seeking. However, little is known about how retired or non-elite athletes engage with support; this lack of empirical data is even more pronounced in the case of sleep disorders. Method A cross-sectional online survey was completed by current and former athletes (n = 946; 495 women, 444 men, 7 non-binary) from all sports and competition levels in seven countries. Self-disclosed diagnosis history, help-seeking behaviours, and functional impact of sleep and mental health disorders were assessed. Results Comparable rates of mental health disorders were observed between current athletes (39.3%) and former athletes (42.0%), OR = 1.17, p = .337. Similarly, comparable rates of sleep disorders were observed between current athletes (25.4%) and former athletes (30.9%), OR = 1.20, p = .298. Men reported lower mental health disorder prevalence than women (32.9% vs. 46.3%), OR = 1.82, p < .001. Gender differences were also evident in the types of disorders reported. For sleep disorders, men were less likely to seek assistance from a psychologist than women (8.4% vs. 26.2%), p < .001,φ = 0.23. No differences in help seeking avenues for mental health were observed. Comorbid disorders had more frequent functional impairment than individual sleep or mental health disorders. Conclusions These self-reported prevalence estimates have significance for practitioners and clinicians. Data indicates the most prevalent types of disorders in these populations and where athletes typically engage in support. Evaluating the time course of these disorders can inform health promotion strategies and treatment methods for practitioners and support staff.

Neighbourhood-level socioeconomic status and prevalence of teacher-reported health disorders among Canadian kindergarten children.

The evidence on the association between neighborhood-level socioeconomic status (SES) and health disorders in young children is scarce. This study examined the prevalence of health disorders in Canadian kindergarten (5-6 years old) children in relation to neighborhood SES in 12/13 Canadian jurisdictions. Data on child development at school entry for an eligible 1,372,980 children out of the total population of 1,435,428 children from 2004 to 2020, collected using the Early Development Instrument (EDI), were linked with neighborhood sociodemographic data from the 2006 Canadian Census and the 2005 Taxfiler for 2,058 neighborhoods. We examined the relationship using linear regressions. Children's HD included special needs, functional impairments limiting a child's ability to participate in classroom activities, and diagnosed conditions. The neighborhood prevalence of health disorders across Canada ranged from 1.8 to 46.6%, with a national average of 17.3%. The combined prevalence of health disorders was 16.4%, as 225,711 children were identified as having at least one health disorder. Results of an unadjusted linear regression showed a significant association between neighborhood-level SES and prevalence of health disorders (F(1, 2051) = 433.28, p < 0.001), with an R2 of 0.17. When province was added to the model, the R2 increased to 0.40 (F(12, 2040) = 115.26, p < 0.001). The association was strongest in Newfoundland & Labrador and weakest in Ontario. Our study demonstrated that the prevalence of health disorders among kindergarten children was higher in lower SES neighborhoods and varied by jurisdiction in Canada, which has implications for practice and resource allocation.

EPH70 Trends in Hospitalizations Related to Anxiety, Depression, and/or Substance Use Among Adult Inpatients from 2016-2020 in the United States

Recent research suggests mental health disorder prevalence is increasing in the United States (US). Trends of anxiety, depression, and substance use (ADSU)-related inpatient hospitalizations from 2016-2020 were analyzed to better understand the impact of this increase on healthcare resource utilization.

Health disorders in workers associated with health risks at workplaces in mining industry in the Arctic (Analytical review)

The review analyzes a range and prevalence of health disorders in workers employed at mining enterprises in the Arctic and exposed to heterogeneous occupational factors. We revealed that working processes typical for basic occupations in under-ground mining involved exposure to a set of heterogeneous harmful and (or) hazardous occupational factors such as intense occupational noise; elevated vibration; aerosols with predominantly fibrogenic effects, dusts and chemicals; high hardness and intensity typical for physical work; non-ionizing electromagnetic radiation. It was shown that diseases of the ear and mastoid, vibration syndrome, diseases of the musculoskeletal system, respiratory diseases and diseases of the nervous system prevailed both in the structure of general morbidity and in occupational one typical for miners. To create proper working conditions and to minimize effects of harmful and hazardous occupational factors as well as occupational health risks, it is advisable to perform comprehensive hygienic assessment of introduced equipment, machinery and mechanisms; to establish levels and doses of occupational factors. Engineering and technical, technological, medical and preventive and treatment and health-improving activities should be developed on this basis with special emphasis on such occupational groups as drift miners, drill-operators, blasters, timbermen, operators of cargo handling machinery, drilling unit operators, miners in mining outputs and faces, repairmen, and electric gas welders. It seems extremely vital to apply risk assessment methodology to assess occupational health risks for workers employed in mining operations in the Norilsk industrial region considering climatic features of the Arctic. This assessment is important for substantiating relevant activities aimed at managing such risks and protecting workers’ health.

Нарушения здоровья работников, связанные с факторами риска условий труда в горнодобывающей промышленности арктической зоны (Аналитический обзор)

The review analyzes a range and prevalence of health disorders in workers employed at mining enterprises in the Arctic and exposed to heterogeneous occupational factors. We revealed that working processes typical for basic occupations in under-ground mining involved exposure to a set of heterogeneous harmful and (or) hazardous occupational factors such as intense occupational noise; elevated vibration; aerosols with predominantly fibrogenic effects, dusts and chemicals; high hardness and intensity typical for physical work; non-ionizing electromagnetic radiation. It was shown that diseases of the ear and mastoid, vibration syndrome, diseases of the musculoskeletal system, respiratory diseases and diseases of the nervous system prevailed both in the structure of general morbidity and in occupational one typical for miners. To create proper working conditions and to minimize effects of harmful and hazardous occupational factors as well as occupational health risks, it is advisable to perform comprehensive hygienic assessment of introduced equipment, machinery and mechanisms; to establish levels and doses of occupational factors. Engineering and technical, technological, medical and preventive and treatment and health-improving activities should be developed on this basis with special emphasis on such occupational groups as drift miners, drill-operators, blasters, timbermen, operators of cargo handling machinery, drilling unit operators, miners in mining outputs and faces, repairmen, and electric gas welders. It seems extremely vital to apply risk assessment methodology to assess occupational health risks for workers employed in mining operations in the Norilsk industrial region considering climatic features of the Arctic. This assessment is important for substantiating relevant activities aimed at managing such risks and protecting workers’ health.

Hygienic integral assessment of the allergy hazard degree of the working conditions for employees exposed to organic aerosols

In the early 2000s, we substantiated the allergy hazard criteria of the working conditions for employees who are in contact with chemical allergens (sensitizing ability degree, exposure intensity, and entry route into the body, combined nature of toxicant and allergen effects, combined exposure to harmful factors of physical nature) that were quantified separately and totally depending on their significance in the formation of professional allergic pathology. On this basis, an integral assessment scale of the allergy hazard degree of the working conditions in production and use of chemical allergens was developed. This shows 4 corresponding allergy hazard degrees of work (slight, moderate, high and extremely dangerous), probable levels of occupational health disorders in employees and the risk for developing occupational allergic pathology.The aim of this work was a hygienic integral assessment of the degree of allergy hazard of employees working under the influence of industrial aerosols of biological nature using the approved approaches and the criteria previously developed for industrial chemical allergens.The article proves the possibility of using the above criteria for hygienic integral assessment of the allergy hazard degree of work performed under the influence of organic aerosols. This is the result of Belarusian scientist-hygienists who developed and implemented the scientific concept and modern methodology of experimental hygienic regulation of the different-origin industrial organic dust content in the air of the working area according to the leading harmful allergic effect on the body of the protein-antigenic complex (PAC) of dust, including the original methods for obtaining soluble high-molecular PAC from dust samples, an objective assessment of the degree of their sensitizing ability and the class of allergy hazard.The analysis of the results on the characteristics of the working conditions for different-profession employees exposed to industrial aerosols of different biological nature with the use of the criteria for quantitative assessment of the allergy hazard of industrial environment factors substantiates their assignment mainly to a high or moderate degree of allergy hazard. For employees working under these conditions, a significant frequency and a severity of shifts in the indicators of various immune system components and the development of mixed-type allergic reactions to protein-antigenic complexes of organic dust have been established, which determines the prevalence of health disorders of predominantly allergic nature, increasing with age. This confirms a potential risk of developing occupational allergic diseases (with a probability of up to 30 %) and an increase in the production-related immune-dependent pathology level.The use of the system of social and hygienic monitoring of integral assessment of the allergy hazard degree of working conditions for employees in different production fields exposed to industrial allergens and the identification of priority production factors in their formation allow a targeted and more efficient implementation of a set of technical and medical measures to prevent occupational allergic and production-related diseases.

Comparative characteristics of the prevalence of health disorders in schoolchildren with standard weight and overweight, including obesity

It has been proven that against the background of overweight and obesity, the risk of systemic chronic diseases increases. The article presents the results of studying the characteristics of the indicators of the prevalence of health disorders in schoolchildren with normal and overweight and obesity in a comparative aspect. A survey was conducted of 2159 schoolchildren aged 7–17 years, including 1096 boys/boys and 1063 girls/girls from 6 schools in the Novosibirsk region. Data on chronic morbidity and pathological afflictions of children were copied according to the data of form N 026/y-2000, for respondents in grades 10–11 with overweight (n = 100 people), data on the length and weight of the body were copied in a longitudinal aspect with the purpose of identifying the age of formation of overweight and obesity in order to build a prospective forecast of the prevalence of overweight and obesity in schoolchildren in grades 1–4 upon reaching the age of 16. Parametric statistical methods were used with the calculation of the mean (M) and standard error of the mean (±Se), as well as the methods of correlation and regression analyses. Differences were considered statistically significant at p &lt; 0.05. The revealed differences in the prevalence of chronic diseases in children with overweight and obesity and in children with normal body weight indicate the significant importance of overweight and obesity in the formation of diseases of the circulatory system, endocrine system, food allergies and flat feet. There were no statistically significant differences in the prevalence of chronic diseases of the digestive system, nervous system, visual impairment (p ≥ 0.05). The data obtained with the predicted prospect of an increase in overweight in primary school students indicate the need for continuous development and implementation of both collective and individual prevention measures aimed at minimizing the risks of developing concomitant diseases.

Health status of recently arrived asylum seekers in their host country: results of a cross-sectional observational study

BackgroundThe World Health Organization (WHO) considers that the heterogeneity of concepts and definitions of migrants is an obstacle to obtaining evidence to inform public health policies. There is no recent data on the health status of only asylum seekers who have recently arrived in their Western host country. The purpose of this study was to determine the health status of asylum seekers and search for explanatory factors for this health status.MethodsThis cross-sectional observational study screened the mental and somatic health of adult asylum seekers who had arrived in France within the past 21 days and went to the Marseille single center between March 1 and August 31, 2021. In order to study the explanatory factors of the asylum seekers' health status, a multivariate analysis was performed using a logistic regression model to predict the health status. Factors taken into account were those significantly associated with outcome (level < 0.05) in univariate analysis.ResultsIn total, 419 asylum seekers were included and 96% CI95%[93;97.3] had at least one health disorder. Concerning mental health, 89% CI95% [85.1;91.4] had a mental disorder and in terms of somatic health exclusively, 66% CI95% [61.4;70.6] had at least one somatic disorder. Women were more likely to have a somatic disease OR = 1.80 [1.07; 3.05]. We found a statistically significant association between the presence of at least one disorder and sleeping in a public space OR = 3.4 [1.02;11.28] p = 0.046. This association is also found for mental disorders OR = 2.36 [1.16;4.84], p = 0.018.ConclusionsDue to the high prevalence of health disorders our study found, asylum seekers are a population with many care needs when they arrive in their host country. The main factors linked to a poor health status seem to be related to a person’s sex, geographical origin and sleeping in a public space.

Risk factors influencing the health of university teachers

BACKGROUND: Emotional burnout syndrome is described in the historical literature. According to various authors, the syndrome develops on average in 50% of contemporary teachers. However, the influence of the syndrome on the health of university teachers and its risk factors have not been sufficiently investigated.&#x0D; AIM: This study aimed to identify and analyze the specific of risk factors influencing the health of university teachers.&#x0D; MATERIALS AND METHODS: An anonymous survey of 1,417 teachers was conducted at humanities institutions of higher education in Moscow, and the results of medical examinations were studied.&#x0D; RESULTS: The prevalence of health disorders and associated risk factors among teachers were studied. The socio-hygienic characteristics of the surveyed teachers were analyzed based on a comprehensive assessment of their emotional state, according to individual diseases. In addition, the methods of improving their health status were determined.&#x0D; CONCLUSIONS: More than half of university teachers have health disorders associated with adverse occupational factors and the moral and psychological climate at work and at home, combined with poor health and socio-hygienic activity indicators. Their management should include health-improving technologies and ensure optimal conditions for professional activity.

Stem Cells, Lithium And Neuropsychiatric Disorders

Mental health disorder prevalence is rising within the United States and worldwide. With this growing incidence, treatment for individuals suffering from such disorders is imperative. Stem cells have shown promising results for treating different ..

Flexibly modeling age trends in the prevalence of co-occurring patterns of substance use and mental health disorders using time-varying effects and latent class analysis

ABSTRACT Background: Substance use disorders (SUDs) and mental health disorders may change and co-occur in complex patterns across adult ages, but these processes can be difficult to capture with traditional statistical approaches. Objective: To elucidate disorder prevalence and comorbidities across adult ages by using time-varying effect models (TVEMs), latent class analysis (LCA), and modeling latent class prevalences as complex functions of age. Methods: Data were drawn from participants who are 18–65 years old in the National Epidemiologic Survey on Alcohol and Related Conditions III (n = 30,999; 51% women) and a subsample who reported a past-year post-traumatic stress disorder (PTSD), mood, anxiety, or SUD based on DSM-5 diagnoses (n = 11,279). TVEM and LCA were used to examine age trends and comorbidity patterns across ages. Results: SUD prevalence peaked at age 23 (31%) and decreased thereafter, while mental health disorder prevalence was stable (20%–26% across all ages). The prevalence of five classes of individuals based on specific combinations of mental health and SUDs varied by age: the Alcohol Use Disorder class had the highest prevalence at age 26, whereas the Mood and Anxiety Disorder classes peaked around age 63. Interestingly, the Poly-Disorder class prevalence was greatest at age 18 but decreased sharply across young adulthood; however, the prevalence of the other high comorbidity class, PTSD with Mood or Anxiety Disorder, remained fairly constant across age, peaking at age 44. Conclusions: Multimorbid mental health disorders (excluding SUDs) persist in prevalence across adult ages. LCA, TVEM, and their integration together hold substantial potential to advance addiction research.

State of Ireland's mental health: findings from a nationally representative survey.

Current information about the prevalence of various mental health disorders in the general adult population of the Republic of Ireland is lacking. In this study, we examined the prevalence of 12 common mental disorders, the proportion of adults who screened positive for any disorder, the sociodemographic factors associated with meeting criteria for a disorder and the associations between each disorder and history of attempted suicide. A non-probability nationally representative sample (N = 1110) of adults living in Ireland completed self-report measures of 12 mental health disorders. Effect sizes were calculated using odds ratios from logistic regression models, and population attributable risk fractions (PAFs) were estimated to quantify the associations between each disorder and attempted suicide. Prevalence rates ranged from 15.0% (insomnia disorder) to 1.7% (histrionic personality disorder). Overall, 42.5% of the sample met criteria for a mental health disorder, and 11.1% had a lifetime history of attempted suicide. Younger age, being a shift worker and trauma exposure were independently associated with a higher likelihood of having a mental health disorder, while being in university was associated with a lower likelihood of having a disorder. ICD-11 complex posttraumatic stress disorder, borderline personality disorder and insomnia disorder had the highest PAFs for attempted suicide. Mental health disorder prevalence in Ireland is relatively high compared to international estimates. The findings are discussed in relation to important mental health policy implications.

Actual issues of hygienic regulation and creation of safe working conditions at pharmaceutical manufacturing enterprises

Introduction. The working conditions of pharmaceutical industry workers are characterized by the combined effect of unfavorable factors of the production environment, among which the leading one is chemical. The aim of study is to substantiate the basic principles and criteria for hygienic regulation of pharmaceutical products in their production to ensure safe working conditions for employees based on the results of their own research and existing requirements of technical regulations. Materials and methods. Analysis of working conditions and the prevalence of health disorders in pharmaceutical workers (according to literature data), toxicological studies of pharmaceutical substances on laboratory animals, scientific justification of hygiene standards in the air of the working area. Results. Among employees of the pharmaceutical industry, the predominant forms of production-related health disorders are diseases of the respiratory system, as well as skin dermatitis of allergic origin, liver and biliary tract diseases. Based on the results of experimental studies of domestic pharmaceutical products for the treatment of cardiovascular, oncological and mental diseases that have priority socio-economic significance, the basic principles and features of the practice of justifying the hygienic standards of medicines in the air of the working area are developed and systematized. Conclusions. During hygienic rationing of medicines, it is necessary to use a differentiated approach that allows, based on the analysis of information about the chemical structure, physical and chemical characteristics, production conditions, pharmacotherapeutic activity, and the results of studying the toxic effect in an experiment on laboratory animals, to determine the maximum permissible content in the air of the working area of medicines or to justify the prohibition of isolation with reasoned recommendations for their safe production.

The prevalence of mental health disorders among young adults who use amphetamine-type stimulants, compared to young adults who do not.

There is a lack of evidence regarding mental health disorder prevalence in people who use amphetamine-type stimulants (ATS). This study compares prevalence in Australian young adults who used ATS and young adults who had never used, and examines potential predictors. Population-based sampling was used to recruit young adults who used ATS (n = 224) and young adults who had never used ATS (n = 125). Thirty-day prevalence of major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder (PD), post-traumatic stress disorder (PTSD) and mania/hypomania were assessed using the Composite International Diagnostic Interview Short Scale. Adjusted prevalence ratios (APR) of mental disorders in people who used ATS and the comparison group were examined, and a prediction model was developed for people who used ATS. We found higher prevalence of PD (APR 4.67, 95% confidence interval [CI] 1.14-19.07, P = 0.032) and PTSD (APR 1.68, 95% CI 1.10-2.55, P = 0.016) in people who used ATS, compared to the comparison group, adjusting for sociodemographic variables. Baseline methamphetamine use was positively associated with MDD (ARR 6.45, 95% CI 1.51-27.59, P = 0.012) and GAD (ARR 2.76, 95% CI 1.52-5.02, P = 0.001). Baseline ecstasy use was negatively associated with GAD (ARR 0.52, 95% CI 0.30-0.92, P = 0.025) and PD (ARR 0.15, 95% CI 0.05-0.48, P = 0.001). PTSD and PD appear to be more common in young adults who use ATS. However, the relationship between ATS use and mental disorders is complex, with divergent patterns of association for ecstasy and methamphetamine use. Mental health screening in people using ATS may improve treatment outcomes.

Changing Rates of Mental Health Disorders Among Veterans Treated in the VHA During Troop Drawdown, 2007-2013.

Nationally representative data on mental health disorder prevalence are critical to set informed mental health priorities and policies. Data indicating mental health diagnoses within our nation's veteran population treated at the Veterans Health Administration (VHA) are available, but have yet to be examined for changing trends to inform both VHA and community care. We use VHA national program evaluation data from a time of increasing military enrollment (2007) to troop draw down (2013) to examine changes over time in the number of diagnoses in veterans receiving VHA services. The number of veterans in all diagnostic categories increased during our study period with the smallest increase in psychotic disorders (8%) and the largest in posttraumatic stress disorder (71%). Trends in behavioral health diagnoses among veterans have important implications for policy and clinician competencies within VHA and community providers as veteran mental health care needs change.

Spontaneous Intake and Long-Term Effects of Essential Oils After a Negative Postnatal Experience in Chicks.

The postnatal period is critical for broiler chicks as they are exposed to potentially stressful environmental changes in the hatchery and during transportation to the rearing houses. The ability of broiler chicks to spontaneously drink essential oils (EO) to mitigate the effects of a negative postnatal experience was tested. Chicks were placed in the rearing facility either immediately (C group), or after a 24 h-delay period (D group) to mimic a delay in transportation possible under commercial conditions. In experiment 1, each group had access to either water only or to water and one EO (cardamom, marjoram, or verbena) from D1 to D13. Verbena EO intake was higher in the D group than in the C group from D1 to D6 and cardamom EO intake was lower in the D group than in the C group from D6 to D13. In experiment 2, half of the groups had access to water only and the other half had both water and the three EO simultaneously. Chicks from D and C groups chose the EO similarly except for cardamom EO with a lower intake being observed in the D than in the C group from D6 to D12. The delayed placement of the D group reduced chicken growth until 34 days of age and temporarily increased the feed conversion ratio, but did not affect their welfare or the prevalence of health disorders. The EO intake did not mitigate the growth reduction in D group chicks, but did mitigate the reduced Pectoralis major muscle yield. In conclusion, chicks were able to make spontaneous choices regarding EO intake according to their postnatal experience when EO were presented individually, but not when presented simultaneously as in our experimental design. The EO intake only partially mitigated the decrease in chicken performance after the negative postnatal experience.

HYPERPARATHYROIDISM AND PARATHYROID LESIONS IN THE ChNPP ACCIDENT SURVIVORS

Study of the status of parathyroid glands in individuals exposed to ionizing radiation as a result of the ChNPP accident and comparison with the general population of Ukraine. Subjects exposed as a result of the ChNPP accident (n = 1,348) and people from the general population of Ukraine (n=655) were examined. Diagnostic ultrasound scan of thyroid and parathyroid glands (PTG) was conducted in all study subjects. The technique of parathyroid ultrasound screening was developed, which led to an increase in the efficiency of their imaging. Additionally, the 25-hydroxyvitamin D (25(OH)D), parathyroid hor- mone, ionized calcium and some other parameters were selectively assayed in serum. High incidence of parathyroid hyperplasia was detected 27-32 years after the irradiation in persons ex- posed as a result of the ChNPP accident, especially in evacuees from the 30-km exclusion zone (71.4%; χ2Yates' = 24.1; р = 0) and residents of radilogically contaminated territories (41.7%; χ2Yates' = 6.45; p < 0.01) having no primary hyperparathyroidism. High prevalence of vitamin D insufficiency and deficiency was revealed in all study subgroups, namely in 83.1 % of the general population of Ukraine along with a bit better vitamin D status in the ChNPP acci- dent survivors i.e. the vitamin insufficiency and deficiency was found in 78.7 % of them. Incidence of hyperparathy- roidism, predominantly of the secondary (normocalcemic) one, was 33.8 % among persons exposed as a result of the ChNPP accident (p > 0.3) being somewhat higher than in the general population of Ukraine (26.1%), despite above- mentioned better supply of vitamin D. There is a widespread insufficiency or deficiency of vitamin D (over 78.7%) in the population of Ukraine in general providing an unfavorable background for the higher prevalence of health disorders associated with calcium and phosphorus metabolism. The latter features parathyroid hyperplasia and musculosceletal, immune, cardiovascular, and endocrine system comorbidities. Such disorders should exacerbate with a secondary increase in parathyroid hormone secretion (26.1 %). Higher incidence of normocalcemic hyperparathyroidism (33.8% versus 26.1%) against a background of better vitamin D status among irradiated individuals indicates the existence of other factors, where the past combined effects of Chornobyl radioactive fallout and external parathyroid exposure are most likely to be involved. This could explain the greater number of cases of parathyroid hyperplasia and hyper- parathyroidism among the exposed subjects. However the additional precise studies are required here with clarifi- cation of the personal data in population groups of the ChNPP accident survivors. Participants of the ChNPP acci- dent clean-up work in the «iodine period» of 1986 are of especial concern here. Besides that, the study population should be expanded with inclusion of subjects exposed in prenatal period.