Objective To investigate the effects of three different ways of feeding on the physical growth of low birth weight premature infants discharged from hospital. Methods 90 premature infants were selected.According to the different feeding methods, the infants were divided into A, B, C groups.Premature infants of A group were fed with preterm infants formula milk after discharge.B group received breast feeding.C group was fed with term infants formula milk.The physical growth at postnatal 30d, 60d and 90d of three groups were observed and compared. Results The weight, length and head circumference of premature infants at postnatal 30d, 90d in A group were better than those of B group and C group, the differences were statistically significant (all P 0.05). The weight, length and head circumference of premature infants at postnatal 60d in A group and B group were better than those in C group, the differences were statistically significant (all P<0.05). Conclusion Compared with the breast feeding and traditional formula milk, formula milk for preterm infants is more conducive to the growth of premature infants to obtain nutrients, effectively promote the growth of premature infants, improve the prognosis and quality of life in preterm infants. Key words: Low birth weight; Premature infant; Feeding pattern; Physical growth