The Peruvian altiplano is a marginal agricultural region with limited infrastructure, climate constraints, and high levels of poverty. Data were collected from 265 farms in four different agricultural regions, and data from three of those regions are analyzed here. Regressions were run with soil nutrient loss, soil depth loss, and yield loss over the past 20 years, as perceived by farmers. Location, topographical and management factors were considered. Additional regressions were run to examine the determinants of two agricultural management practices which were found to affect soil quality, namely fallowing and ploughing vertical furrows. Use of traditional fallowing (aynoca) was associated with helping to preserve soil quality, and was practiced by households with more education, with higher non-farm income, and in villages which had benefitted from natural resource development projects. Vertical furrowing similarly was associated with helping preserve soil quality, and was practiced by households with fewer unmet basic needs. These results have implications for the agricultural and development strategies to be followed in the region.