Preservation Of Parent Artery Research Articles

Treatment of traumatic aneurysms and arteriovenous fistulas of the skull base by using endovascular stents.

The authors describe their preliminary clinical experience with the use of endovascular stents in the treatment of traumatic vascular lesions of the skull base region. Because adequate distal exposure and direct surgical repair of these lesions are not often possible, conventional treatment has been deliberate arterial occlusion. The purpose of this report is to demonstrate the safety and efficacy as well as limitations of endovascular stent placement in the management of craniocervical arterial injuries. Six patients with vascular injuries were treated using endovascular stents. There were two arteriovenous fistulas and two pseudoaneurysms of the distal extracranial internal carotid or vertebral arteries resulting from penetrating trauma, and two petrous carotid pseudoaneurysms associated with basal skull fractures. In one patient a porous stent placement procedure was undertaken as well as coil occlusion of an aneurysm, whereas in the remaining five patients covered stent grafts were used as definitive treatment. There were no procedural complications. One patient in whom there was extensive traumatic arterial dissection was found to have asymptomatic stent thrombosis when angiography was repeated 1 week postoperatively. This was the only patient whose associated injuries precluded routine antithrombotic or antiplatelet therapy. Follow-up examinations in the remaining five patients included standard angiography (four patients) or computerized tomography angiography (one patient), which were performed 3 to 6 months postoperatively, and clinical assessments ranging from 3 months to 1 year in duration (mean 9 months). In all five cases the vascular injury was successfully treated and the parent artery remained widely patent. No patient experienced aneurysm recurrence or hemorrhage, and there were no thromboembolic complications. The authors' experience demonstrates that endovascular treatment of traumatic vascular lesions of the skull base region is both feasible and safe. The advantages of minimally invasive stent placement and parent artery preservation make this procedure for repair of neurovascular injuries a potentially important addition to existing methods.

GDC Embolisation of Cavernous Internal Carotid Artery Aneurysms with Parent Artery Preservation

We evaluated the clinical and angiographic results of endosaccular treatment with Guglielmi detachable coils (GDCs) in 19 cases of cavernous internal carotid artery (ICA) aneurysms. The size of the aneurysms ranged from 10 to 30 mm (mean 18.4 mm) and neck size ranged from 2 to 15 mm (mean 6.7 mm). Intraluminal thrombosis was found in ten cases. Main presenting symptoms were related to mass effect in 17 cases including cranial nerve palsy, headache and vomiting. On initial GDC embolisation, total occlusion was obtained in two cases, subtotal in eight, and incomplete in nine. In two cases with incomplete occlusion, parent arteries were occluded with balloons or GDCs during or just after the procedure because of underlying diseases. A higher rate of initial occlusion was obtained in smaller and non-thrombosed aneurysms. Symptoms resolved or improved in all cases except one after initial treatment. No complication occurred related to the procedure. Follow-up angiography was obtained in 15 cases among which ten cases (66.7%) showed luminal recanalisation. Symptoms recurred in one case with luminal recanalisation. Incidence of recanalisation was similar in both large and giant aneurysms but higher in the thrombosed than non-thrombosed group. Retreatment was done in five cases with success. In conclusion, although embolisation of cavernous ICA aneurysms with GDCs was safe and effective in relieving symptoms, the incidences of initial incomplete occlusion and follow-up recanalisation were high. Therefore, we think judicious selection of the cases is necessary for endosaccular GDC embolisation in cavernous ICA aneurysms.

GDC Embolization of Wide-necked Cerebral Aneurysms Using Balloon-Assisted Technique

Purpose : The main factor limiting endovascular treatment of intracranial aneurysms is the shape of the a-neurysmal sac, especially the width of the neck. We describe an early experience and technical aspects of treating wide-necked cerebral aneurysm using a Guglielmi detachable coil (GDC) and simultaneous applica-tion of a temporary balloon. Materials and Methods : Four cases of unruptured wide-necked cerebral aneurysm were treated with GDC, with simultaneous application of a temporary balloon. Patients were aged between 29 and 49 years. On admis-sion, clinical presentation was subarachnoid hemorrhage (SAH) in all cases. Hunt and Hess grade was II in two cases, III in one case, and traumatic SAH in one case. In all patients angiography revealed an asymptomatic a-neurysm after rupture of another aneurysm or traumatic SAH. The aneurysms were occluded with GDC-10, and a Cirrus balloon occlusion system was used simultaneously. All procedures were performed under endo-tracheal general anesthesia and systemic heparinization. Results : All cases were treated successfully, without parent artery compromise. The occlusion rate at the end of the procedure was total in three cases and subtotal in one. In one case a heparin-related hematoma occurred during post-procedural treatment and the patient eventually expired. One patient underwent follow-up an-giography after 6 months, and the coil was not changed. Conclusion : An aneurysm may not be completely occluded, but with regard to coil compaction and parent artery preservation, the technique is an attractive alternative.

Surgical strategies for giant intracranial aneurysms.

Untreated giant intracranial aneurysms have a dismal natural history as a result of hemorrhage, cerebral compression, and thromboembolism. The poor prognosis of patients with giant aneurysms therefore warrants aggressive treatment. A surgical approach is chosen to maximize the operative exposure of the aneurysm and depends mainly on the aneurysm's location. Once exposed, vascular control of the aneurysm is required not only to manage an intraoperative rupture, but also to collapse the aneurysm, to increase working space, and to improve visualization of the anatomy. Hypothermic circulatory arrest may be indicated in select patients with complex posterior circulation aneurysms. Direct clipping of giant aneurysms, with meticulous preservation of parent and branch arteries, is the preferred method of occlusion. Unclippable aneurysms require alternative techniques (e.g., trapping, parent artery occlusion, excision, and aneurysmorrhaphy) that compromise parent arteries and may require revascularization to restore adequate cerebral blood flow. Giant aneurysms are complex lesions that demand thorough surgical planning, individualized strategies, and a multidisciplinary effort in specialized neurovascular centers.