Abstract Tetraalkllleads (R 4 Pb) reacted quite smoothly with aldehydes R′CHO in the presence of TiCl 4 to produce the corresponding alcohols (RCHOHR′) in high to good yields. The reagent system, R 4 Pb/TiCl 4 , exhibited high chemoselectivity; only aldehydes underwent the alkylation in the presence of ketones. Further, the new reagent exhibited high 1,2- and 1,3-asymmetric induction. The transfer order of alkyl groups in the reaction of aldehydes with mixed tetraalkylleads/TiCl 4 was determined; Me>Et.i-Pr⪢n-Bu.