Presence Of Supernumerary Teeth Research Articles

Third molar agenesis in individuals with supernumerary teeth.

To explore the association between third molar agenesis and supernumerary tooth formation in a white-European population. A record review in various orthodontic clinics identified 380 eligible white-European individuals, half of whom had non-syndromic permanent supernumerary teeth (122 males and 68 females, totalling 244 supernumerary teeth; median age: 13.1, iqr: 1.5 years), and the other half were age- and sex-matched controls with full dentition, excluding the third molars. Tooth sequences were identified in panoramic radiographs. In the supernumerary group, approximately 80% of the individuals had a single supernumerary tooth, followed by those having two additional teeth. In both groups, there was no sexual dimorphism in third molar agenesis severity. The prevalence of third molar agenesis in the supernumerary group was similar to that of the control group (28/190 = 14.7% in both groups; p = 1.0). In total, 53 third molars were missing in the supernumerary group (n = 190) compared to 67 in the control group (n = 190; p = .862). The ratio of bilateral to unilateral third molar agenesis was significantly lower in the supernumerary group than in the control group (1.0 vs. 3.7, respectively; p = .026). The presence of supernumerary teeth did not significantly alter the likelihood of third molar agenesis or its severity. Bilateral third molar agenesis was considerably less prevalent in individuals with supernumerary teeth compared to controls. The present novel findings have important clinical and developmental implications.

Prevalence of Dental Anomalies Among Orthodontic Patients: A Retrospective Study in Saudi Arabia.

Odontogenic anomalies encompass deviations in dental morphology, orientation, or spatial positioning within the mandibular structures. This study probed the frequency of such dental malformations among orthodontic patients receiving treatment in Riyadh City, Saudi Arabia. Furthermore, the study sought to discern variations in the manifestation of these dental anomalies related to gender and nationality. A retrospective analysis was conducted on 384 panoramic radiographs belonging to orthodontic patients (comprising 222 males and 162 females) who sought treatment at orthodontic clinics of a privately owned university hospital in Riyadh City between 2017 and 2019. The patient records were scrutinized for various dental abnormalities, including but not limited to dilacerated teeth, supernumerary teeth, congenital absence of teeth, impactions, hyperdontia, hypodontia, taurodontism, tooth rotation, and amelogenesis imperfecta. The Chi-square test was employed to assess the correlation between the prevalence of dental anomalies and variables such as gender and nationality. A p-value of less than 0.05 was deemed statistically significant for all tests. Among the assessed sample size of orthodontic patients, dental impactions emerged as the most prevalent dental anomaly, affecting 246 patients (64.1%). This was followed by the occurrence of supernumerary teeth in 31 patients (8.1%), hyperdontia in 29 patients (7.6%), and congenital absence of teeth in 28 patients (7.3%). Other less frequently observed dental irregularities included dilacerated teeth in 23 patients (6%), amelogenesis imperfecta in 12 patients (3.1%), taurodontism in 12 patients (3.1%), and tooth rotations in five patients (1.3%). A statistically significant gender-based disparity was observed, with dental impactions being more prevalent among males (n=154; 69.4%) than females (n=92; 56.8%). Conversely, supernumerary teeth were more prevalent among females (n=24; 14.8%) than males (n=7; 3.2%). No significant variation in the prevalence of dental anomalies was discernible across different nationalities. Impactions and the presence of supernumerary teeth were the predominant dental anomalies detected among the studied orthodontic patient population. The prevalence of dental anomalies exhibited discernible variations based on gender but not nationality. These disparities could potentially influence orthodontic outcomes, underscoring the necessity for meticulous examination and tailored orthodontic treatment planning.

Gardner's Syndrome—A Case Report and Brief Literature

AbstractGardner's syndrome has been recognized as a hereditary affliction that is autosomal in nature. This disorder is known to exhibit characteristics of familial adenomatous polyposis, of which it is also considered a variation. The features of this syndrome include the gradual development of osteomas and epidermoid cysts, including a characteristic feature that is the noted presence of intestinal polyps, which are generally multiple in number. Additionally, dental anomalies have been observed and recorded in a sizeable ratio of cases encompassing an increased frequency of multiple odontomas that are benign tumors linked to the development of a tooth and tooth agenesis/hypodontia that refers to developmental absence of one or more teeth. The other dental ascertainment includes abnormal morphology of the tooth/teeth as well as the presence of supernumerary teeth and impacted or unerupted teeth. This case report outlines the case of a 59-year-old male patient who had reported to the clinic, and was then diagnosed with Gardner's syndrome post a thorough examination. On radiographic examination, the manifestation of multiple osteomas in the frontal bone was revealed. The presence of a motley of diffused benign lesions of the bone in both the upper and lower jaw as well as the presence of an epidermoid cyst on the scalp was suggestive of an exemplar presentation of Gardner's syndrome.

Complexity of dental management of a pediatric patient with lamellar ichthyosis: case report

The purpose of this case report is to describe the complexity of dental management of a pediatric patient with lamellar ichthyosis. A 9-year-old male patient was referred by the pediatrician to the special needs’ clinic with a major complaint of "tooth in the roof of the mouth", according to the person in charge. The patient's mother reported that he was diagnosed with lamellar ichthyosis at birth and regularly followed up with a medical team, including a cardiologist, due to the presence of mild pulmonary valve stenosis. The physical examination revealed presence of skin peeling, everted lip, mouth breathing, cognitive deficit, and speech delay. The intraoral clinical examination showed mixed dentition, absence of caries lesions and presence of supernumerary teeth on the palate, between teeth 11 and 21, which was confirmed by radiographic examination. Although he was cleared by the pediatrician and cardiologist for the procedure under general anesthesia, this procedure in the hospital setting was interrupted at the last minute and contraindicated by the anesthesiologist, as it would be a high risky due to the patient's airway conditions. Thus, one month later, the patient's surgery was performed under local anesthesia on an outpatient basis under sedation and protective stabilization. The patient remains on follow-up and receiving preventive treatment. Thus, it is fundamental that there is a multidisciplinary approach of these patients to prevent possible complications resulting from dental procedures. In addition, regular dental monitoring is essential to avoid subjecting the patient to invasive procedures.

Sürnümerer Diş Gözlenen Çocuklarda Diş Gelişiminin Değerlendirilmesi: Olgu Kontrol Araştırması

Objective: The term supernumerary tooth is one of the important dental anomalies affecting children and is used to describe excess teeth in the dental arch. Knowledge of changes in tooth development accompanying supernumerary teeth provides information about both orthodontic problems and changes in bone and teeth. This study aims to evaluate the relationship between the presence of supernumerary teeth and dental development in children and to raise awareness about the conditions associated with the presence of supernumerary teeth. Material and Methods: 175 (114 males and 61 females) children with supernumerary teeth were examined and compared to 175 normal control subjects matched for sex and age. Dental development was evaluated from panoramic radiographs using the dental age estimation method of Demirjian et al. Data were statistically analyzed using the Shapiro-Wilk test. Results: Significant differences were found in the mean of dental age and chronological age difference between case controls and children with supernumerary teeth (0.4±0.7 and 0.8±0.7 years, respectively). The mean differences between dental age and chronological age in hyperdontic males and females were 0.77±0.7 years and 0.96±0.7 years, respectively, and the results of the controls were 0.39±0.7 for males and 0.47±0.8 years for females. The differences between the hyperdontic and control groups were significant for both genders (p<0.001). Conclusion: Children with supernumerary teeth appear to have advanced dental development compared to children with normal dentition. The presence of supernumerary teeth in children is a condition that affects dental development.

Frequency and Local Etiological Factors of Impaction of Permanent Teeth among 1400 Patients in a Greek Population.

Background: The purpose of this study is to analyze the frequency of impaction of permanent teeth, beyond the third molars, and to highlight the factors causing this condition. Methods: Panoramic radiographs of 1400 patients that sought orthodontic treatment in private practice were retrieved and examined. All teeth that had not been erupted at the time of the examination while their root formation was completed were considered impacted. Results: In total, 212 out of 1400 patients had at least one impacted tooth (15.14%). The highest incidence of tooth impaction was in the canines of the maxilla, followed by the central incisors of the maxilla, the second molars of the mandible and the second premolars of the mandible. The most common etiological factors responsible for the impaction were the ectopic eruption pathway, loss of space in the arch, the ankylosis of the deciduous teeth and the presence of supernumerary teeth. Conclusions: Tooth impaction is frequently seen in everyday orthodontic practice. The upper canines are the teeth most frequently associated with impaction and failure of eruption. It is important to diagnose cases of impaction early on and identify the etiological factors in order to achieve immediate and effective treatment per patient.

Assessment of risk factors and molecular biomarkers in children with supernumerary teeth: a single-center study

BackgroundSupernumerary teeth are considered one of the commonly observed dental anomalies in children. Several theories have been proposed to explain the presence of supernumerary teeth, including environmental and genetic factors. This study aimed to identify the different risk factors and molecular biomarkers in patients presented with supernumerary teeth.MethodsThis case–control study included 240 children, 6 to 12-year-old. They were divided into a test group (n = 120 children presented with supernumerary teeth) and a control group (n = 120 children with no supernumerary teeth). Questionnaires were distributed to assess demographics and exposure to several environmental factors. Ten extracted supernumerary teeth from the test group were processed for histopathological analysis.ResultsMale gender, dental history of severe oral infection or medical history of chemotherapy treatment, previous history of taking medication or illness during pregnancy, family history of neoplastic disorders, use of electronic devices, and living beside agricultural fields or industrial areas were found to be statistically significant associated with the risk of supernumerary teeth development. Immunohistochemistry panel revealed that supernumerary teeth showed enhanced expression of wingless (Wnt) and sonic hedgehog (SHH) proteins as well as a reduced expression of adenomatous polyposis coli (APC) protein, denoting molecular derangement in a group of pathways classically believed to be involved in its pathogenesis.ConclusionsMales were more frequently affected by supernumerary teeth than females. Several risk factors were notably correlated with the existence of supernumerary teeth. Additionally, molecular biomarkers assessment demonstrated a high expression level of pro-tumorigenic proteins such as Wnt and SHH in patients with supernumerary teeth.

Retention of Central Incisors Caused by Four Supernumerary, Molariform Teeth in A Non-Syndromic Patient

The presence of supernumerary teeth is one of the most common factors that can alter the normal eruption pattern. We present here a rare phenomenon of four, molariform mesiodentes in a systemically healthy, non-syndromic patient, with non-contributory family history, causing delayed eruption of permanent, upper, central incisors. Multiple supernumerary teeth can be an important component of distinctive disorders and a valuable clue for their early diagnosis. However, this case highlights the importance of non-hereditary factors in the pathogenesis of multiple supernumerary teeth in a non-syndromic patient.

Supernumerary teeth in premolar and molar area on CBCT: a pictorial review.

Objective: to build a descriptive classification of premolar and molar supernumerary teeth (ST) when preparing the cone beam computed tomography (CBCT) report. The aim is also to share wide range of CBCT images in the open access publishing model. Material and methods: For our review we systematically searched for articles from PubMed with 1) free full texts on ST in molar and premolar area and using CBCT, and 2) articles providing with information on complications related with the presence of ST in molar and premolar area. We also added to our review studies providing with classic ST classifications in premolar and molar area. Results: We found 29 cases of ST, and we freely illustrated them with 84 figures. We separated our pictorial review in: 1) unilateral ST in the mandible, 2) unilateral ST in the maxilla, 3) unilateral undersized ST, 4) bilateral ST, 5) ST with additional features, and 6) cases with major hyperdontia. Conclusions: we build up the classification matrix for premolar and molar ST with 11 descriptors and 50 boxes. The descriptors were: 1) location if the ST crown in axial view, 2) vertical location of the cusp tip in relation with closest erupted tooth in coronal view, 3) shape, 4) distribution, 5) Position (in relation to normal tooth eruption) in sagittal view, 6) State of eruption of the ST in the sagittal view, 7) Follicle size measurement in sagittal view, 8) External root resorption of adjacent teeth by ST and its location in relation to the long axis of the involved tooth, 9) Internal resorption of ST, 10) Adjacent tooth complication, and 11) Damage to surrounding structures if ST removal. The open access figures from the literature illustrated 11 boxes. With our pictorial review we were able to illustrate 45 out of 50 boxes, and freely provide the readership with the most complete description of ST in premolar and molar area on CBCT than in previously published studies.

Imaging characteristics of enamel pearls on CBCT and their co-relation with supernumerary tooth.

Enamel pearl (EP) is an ectopic growth of enamel that is generally round and white and it firmly adheres to the external root surface of tooth. The aim of this study was to assess the prevalence and imaging features of enamel pearls (EPs) and to investigate the potential relationship between EP and supernumerary tooth. Cone beam computed tomography (CBCT) images of 1003 patients were evaluated for the presence of EP. Descriptive characteristics of gender and age of patients and imaging features of EPs and presence of supernumerary tooth were recorded. In this study, 72 EPs were radiographically detected in 63 molars in 43 patients, with a person prevalence of 4.29% and tooth prevalence of 0.71%. Most of the EPs (95.83%) were detected in maxillary molars especially in third (n = 42, 58.33%) and second molars (n = 18, 25%). They were more frequently located at mesial (n: = 21; 29.16%); distal (n = 16; 22.22%) proximal surface of roots and the furcation between the disto-buccal and the palatal roots (n = 12; 16.67%) respectively. CBCT images of 109 (10.87%) patients showed supernumerary tooth/teeth and 13 of these also presented EP. A statistical significant relationship between supernumerary tooth and EP was found (p = 0.001). Additionally, CBCT images of four EPs showed corticated hypodens tracts similar to gubernaculum dentis (GD). Clinicians and radiologists should be aware that EPs are most frequently observed in maxilla especially in third and second molars. Presence of supernumerary tooth might be associated with higher presence of EPs.

Beybağ (Muğla) Bizans Popülasyonunda Gözlenen Konjenital Diş Eksikliği (Hipodonti-Agenesis) ve Süpernümerer Dişler

Aim: The aim of this study was to investigate the hypodontic (agenesis) and supernumerary tooth formation observed in the Byzantine community of Beybağ, Muğla. Material and Method: During the Beybağ excavations, 161 graves which were unearthed in 2008 were dated to the Byzantine Period. 97 (mandible and/or maxilla) jaw bones obtained from 171 individuals constitute our study material. It was determined that the jaw bones of these 97 individuals belonged to 39 male, 26 female and 32 infant-child. For this purpose, those jaw bones were examined and the jaw bones that were estimated to be hypodontic were radiographically visualized with Kavo 3D exam dental tomography device. In addition, the presence of supernumerary teeth was examined by macroscopic observation. Results: Following examination of materials, hypodontia in five individuals and supernumerary tooth samples in one individual was determined. According to these findings, the incidence of supernumerary teeth in the Byzantine community of Beybağ was found to be 1.03% and the frequency of agenesis was 7.21%. However, only one case of a supernumerary tooth was observed in the maxilla (upper jaw). Conclusion: It was observed that the results we obtained in both the frequency of supernumerary teeth and the frequency of hypodontia (agenesis) in the study yielded similar results with both recent studies and previous studies. We think that this study, which is one of the rare examples, will contribute to other studies in this research field.

Ectopic eruption of the first permanent molar: Predictive factors for irreversible outcome

The present study aimed to analyze possible factors involved in irreversible (IRR) ectopic eruption (EE) of the first permanent molar and explore potential predictors for the IRR outcome. Children aged 4-11years, with at least 1 EE and who took their first panoramic radiograph before the age of 8years, were selected in this study. The subjects were assigned to the self-correcting (SC) and IRR groups. Patients' age, sex, distribution of EE, and accompanying dental anomalies were recorded. Eruptive angulation (EA) of the first permanent molar, the grade of root resorption in the second deciduous molar, the magnitude of impaction index (MOII), and horizontal distance were measured on the panoramic radiographs. Chi-square tests and independent-sample t test were used for nominal and continuous variables, respectively. The receiver operative characteristic curve was used to determine the critical value. A total of 406 children with 634 first permanent molars, presenting EE, were enrolled, with 61.3% of the teeth in the SC group. Sex of children with EE and distribution of EE were not relevant to the IRR outcome. The presence of supernumerary teeth might be a protective factor for the IRR outcome. The increasing severity of root resorption in the second primary molar indicated an IRR outcome. A higher MOII and a larger EA suggested an IRR outcome with moderate-to-high quality. The horizontal distance exhibited debatable results, with a low predictive quality. Close monitoring and early intervention would benefit children with increasing severity of distal atypical resorption in the second primary molar, higher MOII, and larger EA.

SUPERNUMERARY PREMOLARS IN MAXILLA AND CONCRESCENCE OF ROOTS – case report

The presence of supernumerary teeth is not uncommon in the general population. Supernumerary teeth (hyperodontia) appear more in permanent dentition. Supernumerary teeth which are in the premolar region occur more often in the mandible with different shape and size. They might occur singly or in multiples, be erupted or impacted. The reason of hyperodontia is still unknown. There are a lot of theories. Various theories have been suggested to explain the etiology of supernumerary teeth in general including both, the genetic theory and environmental factors. Furthermore, it has been suggested that supernumerary premolar teeth belong to a third (postpermanent) series. Proliferation of dental lamina has been implicated. The presence of supernumerary teeth usually is connected with some disease or syndromes. Treatment of hyperodontia depends on the area where supernumerary teeth occur. This article presents a case report of an 11-year-old girl with hyperodontia of the first premolar, erupted palatinally in the left side of maxilla. This is supplemental tooth that looks like the permanent premolar. The orthopantomogram and 3D radiograph showed a big possibility of concrescence of both premolars. To make a definitive diagnosis and a plan for orthodontic treatment, OPG and 3D radiograph were crucial. Keywords: supernumerary teeth, concrescence, OPG, 3D radiograph, orthodontic treatment

Dental and maxillomandibular incidental findings in panoramic radiography among individuals with mucopolysaccharidosis: a cross-sectional study

Mucopolysaccharidosis (MPS) is a group of rare and inherited metabolic disorders caused by the accumulation of macromolecule glycosaminoglycans inside lysosomes. Affected individuals may have dental and craniofacial tissue alterations, facilitating the development of several oral diseases. Objectives To assess, with panoramic radiographic images, the frequency of dental and maxillomandibular incidental findings among MPS individuals and compare them with non-MPS individuals.Methodology A cross-sectional study evaluating a sample of 14 MPS individuals and 28 non-MPS individuals aged from 5 to 26 years was carried out. They were matched for sex and age on a 2:1 proportion. Panoramic radiographs were assessed for the presence/absence of the following dental and maxillomandibular alterations: dental anomalies of number (hypodontia/dental agenesis, supernumerary teeth); anomalies of form (microdontia, macrodontia, conoid teeth, taurodontism, and root dilaceration); anomalies of position (impacted tooth, inverted tooth, tooth migration, partially bony teeth, complete bony teeth); periapical alterations (furcation lesion, circumscribed bone rarefaction); other alterations (radiolucent bone lesions, radiopaque bone lesions, radiopacity in the maxillary sinus, condylar hypoplasia). Differences between groups were tested by the Fisher’s exact test and chi-square test (p<0.05).Results For intrarater agreement, Kappa values were 0.76 to 0.85. The presence of supernumerary teeth (p=0.003); conoid teeth (p=0.009); taurodontism (p<0.001); impacted teeth (p<0.001); partial bony teeth (p=0.040); complete bony teeth (p=0.013); and root dilaceration (p=0.047) were statistically more frequent in MPS individuals compared to non-MPS individuals. Bone rarefaction/furcation lesions (p=0.032), condylar hypoplasia (p<0.001), radiolucent bone lesions (p=0.001), and dentigerous cysts (p=0.002) were also more frequent in MPS individuals.Conclusion The presence of specific oral manifestations is more common in MPS individuals than non-MPS individuals.

Supernumerary and Supplementary Teeth in a Non-syndromic Patients

Background Irregularities in the number of teeth can also occur in deciduous and in permanent dentition. Objective The aim of this article is to report the case of a seven years old child and a 27 years old male patient affected by a numeric dental anomaly. Methods This paper has shown the pathologic condition characterized by the presence of supernumerary tooth (mesiodens) and supernumerary canine as well as supplementary premolars in a non-syndromic patients. Clinical and instrumental examinations were made to perform a correct orthodontic examination and diagnosis. A young patient was affected by numeric dental anomaly in the upper jaw. An adult patient was affected by numeric anomaly in both jaws, supplementary premolars in lower jaw and a supernumerary canine in lower and upper jaw. Discussion The aim of surgical-orthodontic treatment was extraction of the erupted supernumerary teeth to obtain the physiologic eruption and placement of the permanent ones. Conclusion Therapy of supernumerary/ supplementary teeth is the extraction. But also, an excess tooth in the dentition can be left as a replacement tooth, due to a previously lost permanent tooth from the dentition, if its biological value and potential is sufficient to complete the dentition both functionally and aesthetically.

Evaluation of Sella Turcica Bridging and Morphology in Different Types of Cleft Patients.

ObjectivesTo evaluate sella turcica (ST) bridging, associated anomalies, and morphology, in subjects with four different types of clefts, and compare them with non-cleft (NC) subjects.Materials and MethodsA total of 123 (31 NC and 92 cleft) Saudi subjects who had their lateral cephalogram (Late. Ceph.), orthopantomogram (OPG), and clinical details for ordinary diagnosis were included in the study. Among 92 cleft subjects, 29 had bilateral cleft lip and palate (BCLP), 41 had unilateral cleft lip and palate (UCLP), nine had unilateral cleft lip and alveolus (UCLA), and 13 with unilateral cleft lip (UCL). ST bridging and seven parameters related to ST morphology and skeletal malocclusion were analyzed using Late. Ceph. Associated dental anomalies in ST bridging subjects were investigated using OPG. The images were investigated using artificial intelligence driven Webceph software. Multiple statistical tests were applied to see the differences between gender and among cleft vs NC subjects.ResultsST bridging was found to be higher in cleft subjects (22.82%). Most of the cleft subjects had severe skeletal Class III malocclusion associated with multiple types of dental anomalies (impacted canines, congenital missing, and presence of supernumerary teeth). No significant gender disparities in all seven parameters of ST morphology were found between NC and cleft groups. However, there were significant differences when compared among four different types of cleft individuals vs NC subjects.ConclusionST bridging is more prevalent in cleft subjects along with Class III malocclusion and associated dental anomalies. ST morphometry differs significantly between cleft vs NC subjects. BCLP exhibits smaller values of all seven parameters as compared to all other groups.

Clinical and Epidemiological Study of Supernumerary Teeth in Patients from Plovdiv Region

Abstract Abnormalities in the number of teeth are conditions that occur predominantly in childhood. Therefore, monitoring the prevalence and early diagnosis is very important for the timely and appropriate therapeutic approach. The aim of the study was to investigate the incidence of supernumerary teeth in patients from the city of Plovdiv. Methods and equipment: 1,000 dental patients were studied. Data were collected from patients seeking medical attention at the Faculty of Dental Medicine in Plovdiv. We used clinical, X-ray and statistical methods for investigation. Results: A 1.1% prevalence of supernumerary teeth (ST) was observed in the studied patients. A statistically significant difference was found between the presence of ST in the permanent and mixed dentition, with a 3% relative proportion of ST in the mixed and 0.62% in the permanent dentition (p &lt; 0.05). The relative proportion of ST in the maxilla was 90.9%, and in the mandible – 9.1%. A statistically significant difference (p &lt; 0.05) was found in the distribution of ST by jaws. In our study, a higher frequency of mesiodens and distomolar (1.08% and 0.22%, respectively) was found in males, and a decreasing relative proportion from the midline to distally in females (mesiodens – 0.56%, paramolar – 0.19%, distomolar – 0.19%). Conclusion: Supernumerary teeth are a relatively rare dental abnormality in the Bulgarian population. Its distribution by sex and morphology corresponds to the prevalence in Caucasians and populations of southern countries.

Agenesia de terceros molares y su asociación con otras anomalías dentales en una población peruana.

Objective: The purpose of the present study was to determine the association between agenesis of the third molar and other dental anomalies. Materials and Methods: This was an observational, retrospective, cross-sectional and analytical study. The sample included 367 patients, aged 14 to 20 years old with adequate digital panoramic radiography. Patients with syndromes, who had extractions of any third molar and with orthodontic treatment prior to panoramic radiographic examination, were excluded. For data collection, each radiograph was recorded with patient code, sex and age. Results: The prevalence of third molar agenesis was 20.71%. Subsequently, patients were divided into two groups, with agenesis of at least one third molar and a control group; the prevalence of other dental anomalies was 48.69% of third molar agenesis group and 21.31% in the control group. A highly significant association was found between the presence of third molar agenesis and the presence of other tooth abnomalities (p= 0.0000; contingency coefficient = 0.2425).The most frequent dental anomaly was dental inclusion with 20.44% of the population studied; followed by the agenesis of other teeth (7.90%) and finally the presence of supernumerary teeth (1.63%). Conclusions: This study demonstrates that there is an association between third molar agenesis and other dental abnormalities, with a higher prevalence of dental abnormalities in patients with third molar agenesis.

Impaired dentin mineralization, supernumerary teeth, hypoplastic mandibular condyles with long condylar necks, and a TRPS1 mutation

Tricho-rhino-phalangeal syndrome type I, an autosomal dominant condition, is caused by heterozygous pathogenic variants in a zinc finger transcription factor, TRPS1, which has important roles in development of endochondral bones, teeth, and hair. Clinical manifestations of the patients include short stature, sparse, fine and slow-growing scalp hair, bulbous nose, supernumerary teeth, hip dysplasia, brachydactyly, and cone-shaped epiphyses of the phalangeal bones. ObjectiveTo clinically, radiographically, and molecular genetically investigate a patient with tricho-rhino-phalangeal syndrome type I. Materials and methodsClinical and radiographic examination and mutation analysis of TRPS1 were performed. ResultsClinical and radiographic examination indicated the patient had tricho-rhino-phalangeal syndrome type I. Sequencing of the TRPS1 gene revealed a heterozygous pathogenic variant (c.2762G>A; p.Arg921Gln). Oral examination showed supernumerary teeth, large dental pulp spaces, dental pulp stones, microdontia of the maxillary permanent lateral incisors, absence of the mandibular left second premolar and short root of the maxillary right second premolar, and hypoplastic mandibular condyles with long condylar necks. ConclusionTRPS1 has an important function in regulating bone and dentin mineralization. Having large dental pulp spaces suggests that impaired dentin mineralization was the result of the TRPS1 pathogenic variant. This is the first patient with a TRPS1 pathogenic variant who had impaired dentin mineralization. This is also the third report showing the association between TRPS1 pathogenic variants and the presence of supernumerary teeth.

EVALUATION OF OCCURRENCE OF HYPERDONTIA IN NON-SYNDROMIC POPULATION FROM BIHAR REGION

It is evident that hyperdontia is more common in the permanent dentition than in the primary. There is a considerable difference between males and females in the prevalence of these teeth in permanent dentition; hyperdontia is twice as common in males as in females. However, this approximation varies in terms of location, other associating syndromes that may be present, and the ethnicity of the individual. In terms of ethnicity, it can be seen that hyperdontia is in fact less common in Caucasian than in Asian populations. There is evidence to show that an individual is more likely to have hyperdontia if other members of their family also have the condition. Hence the present study was planned for evaluation of occurrence of hyperdontia in non-syndromic population from Bihar Region.&#x0D; The present study was planned in Public Health Dentistry, Patna Dental College and Hospital, Patna, Bihar. Total 195 patients referred to Department of Dentistry were evaluated in the present study. Panoramic radiographs and clinical records of patients above the age of 18 years and without any syndromic features were selected for the study. All the radiographs were examined for the presence of supernumerary teeth, their location, morphology, and number. Morphologically, teeth were classified as conical, tuberculate, supplemental, and odontoma.&#x0D; Early diagnosis of dental anomalies can prevent some esthetic, orthodontic, and periodontal problems, and knowledge of the prevalence and distribution of the anomalies may help clinicians to the detection of these anomalies at early stages. Our study evaluated the prevalence of selected dental anomalies; future studies should investigate the prevalence of dental anomalies of all types.&#x0D; Keywords: Hyperdontia, non-syndromic, panoramic radiograph, supernumerary teeth, etc.