This article contains the results of the lithic analysis of assemblages from the Neolithic sites of Kargadur and Vižula in southern Istria, Croatia. The assemblages have been analysed in terms of reduction strategies and typology, with a special focus on raw material analysis and petrographic analysis. During the Early Neolithic, and especially the Middle Neolithic, raw materials circulated the Istrian peninsula, as evidenced by the presence of obsidian and other non-local (exogenous) chert at several sites. Obsidian is certainly an exotic material in this region, and items found at Kargadur come from the Aeolian islands. With these results we have tried to gain a better understanding of lithic production of the period, the approach of the Neolithic people to raw materials and the scope of the distribution network of high-quality chert.