Preparation Activity Research Articles

A combinatorial neural code for long-term motor memory.

Motor skill repertoire can be stably retained over long periods, but the neural mechanism that underlies stable memory storage remains poorly understood1-8. Moreover, it is unknown how existing motor memories are maintained as new motor skills are continuously acquired. Here we tracked neural representation of learned actions throughout a significant portion of the lifespan of a mouse and show that learned actions are stably retained in combination with context, which protects existing memories from erasure during new motor learning. We established a continual learning paradigm in which mice learned to perform directional licking in different task contexts while we tracked motor cortex activity for up to six months using two-photon imaging. Within the same task context, activity driving directional licking was stable over time with little representational drift. When learning new task contexts, new preparatory activity emerged to drive the same licking actions. Learning created parallel new motor memories instead of modifying existing representations. Re-learning to make the same actions in the previous task context re-activated the previous preparatory activity, even months later. Continual learning of new task contexts kept creating new preparatory activity patterns. Context-specific memories, as we observed in the motor system, may provide a solution for stable memory storage throughout continual learning.

The capacity limitations of multiple-template visual search during task preparation and target selection.

Visual search is guided by mental representations of target-defining features (attentional templates) that are activated in a preparatory fashion. It remains unknown how many templates can be maintained concurrently, and what kind of costs are associated with multiple-template versus single-template search. Here, we compared the operation of attentional templates during three-color and single-color search tasks. Preparatory template activation processes were tracked by measuring N2pc components to task-irrelevant singleton color probes that appeared in rapid succession during the interval between search displays. These probes attract attention (as indexed by an N2pc) if the corresponding color template is active at the time when the probe appears. In a three-color search task where target identity was fully predictable (Experiment 1), only probes that matched the upcoming target color triggered N2pcs, demonstrating that only a single target template was activated. When three possible color targets appeared randomly and unpredictably (Experiment 2), probes that matched any of these colors triggered N2pcs, demonstrating that all three templates were activated concurrently. However, relative to a single-color search task, clear costs emerged in this three-color task for attentional guidance toward search targets and for search performance. These costs appear to be linked to inhibitory interactions between simultaneously active search templates. These findings show that while at least three target templates can be maintained in parallel, multiple-template search is still subject to capacity limitations which affect both template-guided attentional guidance and the subsequent selective processing of search targets.

Evaluating progress towards implementation of the European HTA Regulation: Insights generated from the European Access Academy's multi-stakeholder survey

ObjectivesWe conducted a multi-stakeholder survey to assess stakeholders' perceptions of the progress made towards the implementation of the European Regulation on Health Technology Assessment (EU HTA R) and to identify and prioritize the remaining challenges for implementation. MethodsUsing two iterative Delphi cycles, an exploratory, semi-quantitative survey was developed to identify how stakeholders 1) experienced preparatory activities of the Regulation, and 2) prioritized remaining challenges for successful implementation. The survey was distributed among the network of the European Access Academy and via social media to ensure coverage of key stakeholders. Descriptive analyses were performed on quantitative response items, and relative importance was calculated for ranking items. Free-text responses supplemented participants' answers to quantitative questions. ResultsN = 61 responses were received from N = 15 countries including Global/ EU-wide institutions (Patients and Patients’ representatives: 7; Clinicians’ representatives: 5; Regulators: 3; Health Technology Developers (HTDs): 20; HTA bodies: 10; Payers: 7; Policy Makers: 2; Academic representatives: 7). The majority of respondents were aware of preparatory activities, with 74 % (N = 45) observing the drafting of Guidance Documents and 64 % (N = 39) noting the establishment of the Coordination Group. Respondents ranked the success of preparatory activities neutral with a slight tendency towards a positive ranking. Key challenges were Member States' readiness for Joint Clinical Assessments, HTA capacity/ capability constraints, and the applicability/ feasibility of the methodological framework. ConclusionsThis study identified the key remaining challenges for the successful establishment of the EU HTA process. Key findings emphasize the readiness of national systems and procedures as pivotal factors. Balancing operational efficiency with strategic objectives, including the development of a European Value Framework, is imperative for harnessing the full potential of the joint HTA process and enhancing patient access to innovative technologies on a pan-European scale. Public interest summaryIn January 2022, the European Union (EU) adopted the European Regulation on Health Technology Assessment (HTA). By harmonizing HTA practices and promoting collaboration across Member States, the joint procedure as set out in the regulation aims to improve efficient use of resources and ensure long-term sustainability of EU-wide HTA cooperation. Close to reaching the half-way mark of the preparation phase in mid-2023, we conducted a multi-stakeholder survey to assess perceptions of the progress made towards implementation of a joint procedure and to prioritize remaining challenges. The responses indicated a neutral to positive perception of the preparatory activities (i.e., establishing a coordination group and a stakeholder network, and creating guidance documents). Respondents prioritized challenges related to the readiness of Member States, limitations in HTA capacity and capability, and applicability of the assessment methods. Further research is needed to define targeted strategies for specific stakeholder groups to effectively address the identified challenges.

Algorithmic human resource management: toward a functional affordance perspective

PurposeOrganizations are increasingly deploying algorithmic human resource management (HRM) for decision-making. Despite algorithms beginning to permeate HRM practices, our understanding of how to interpret and leverage the functions of algorithmic HRM remains limited. This study aims to review the stock of knowledge in this field of algorithmic HRM and introduce a theoretical perspective of functional affordance to enhance the understanding of the value of algorithmic HRM.Design/methodology/approachA systematic literature review was conducted in this study based on 283 articles. The articles are extracted from the Web of Science and Scopus. The content of the articles was then integrated to formulate the framework for this study.FindingsFunctional affordance highlights algorithmic HRM can be systematically embedded within the organizational environment, with its characteristics naturally suggesting the functionalities or actions available for HR managers to choose from. The findings of this study demonstrate five features of algorithmic HRM from the perspective of functional affordance: awareness of algorithmic HRM, alignment with business model design, action readiness, adaptation to business context and attribution to individuality.Originality/valueThis study provides a novel perspective for understanding the insufficiently theorized application of algorithmic HRM within organizations. It presents an integrated framework that elucidates the key features of algorithmic HRM and elaborates on how organizations can better develop algorithm-driven capabilities based on functional affordance.

“Between formulas and freestyle” – a qualitative analysis of peer tutor preparation and its impact on peer relations

BackgroundPeer tutorials are widely used in medical and health professions education. Some evidence suggests that peer tutorials can have positive effects for student peer tutors and tutees alike. To promote these positive effects, peer tutors are often prepared for their tasks. However, detailed information about this preparation is missing in the literature. The present study thus examines from the tutors’ perspective how peer tutor preparation is conducted, both in interprofessional and uniprofessional contexts, and how this preparation affects peer relations.MethodsA qualitative design was used for the study. For data gathering, three online focus group discussions were conducted with student peer tutors from uniprofessional and interprofessional settings who had a background in health professions. Data were analysed inductively via thematic analysis.ResultsA total of 19 individuals participated in three focus group discussions (n = 6/n = 6/n = 7). From the participants’ perspective, preparation measures were heterogenous. Of a wide range of different measures, some were perceived as more helpful, others as less helpful. In analysing the data, three relevant themes came up which were dereived from the peer tutors’ perspective: roles, eye level, and (self-)trust. All three themes were found to be closely related and appeared to have a direct influence on peer relations. This influence on the learning/teaching process was either positive or negative depending on the respondents’ experiences.ConclusionFrom the peer tutors’ perspective, the preparation they received affected their relationships with their peers in a variety of ways, influenced by the context and the peer tutors’ needs. This finding should be taken into account when planning and implementing future preparatory activities. In addition, further pedagogical considerations and discussions about preparatory activities for peer tutors and their potential impact on social and cognitive congruence are needed.

Learning Analytics Dashboard Design and Evaluation to Support Student Self-Regulation of Study Behaviour

For university students, self-regulation of study behaviour is important. However, students are not always capable of effective self-regulation. Providing study behaviour information via a learning analytics dashboard (LAD) may support phases within self-regulated learning (SRL). However, it is unclear what information a LAD should provide, how to present information in a usable manner, and what the information’s perceived usefulness is in supporting self-regulation of study behaviour. This study entails a sequential mixed design: assessing information needs in focus groups (n=7), exploring usability via think-aloud interviews (n=8), assessing usability with the System Usability Scale (n=42), and assessing perceived usefulness via interviews (n=16). Results showed that students and tutors agreed on the relevance of the constructs chosen from literature but differed in ranking the importance of new constructs. Usability exploration led to several design improvements. Perceived usefulness assessment showed the LAD supported the appraisal of study behaviour. A need for reference frames to facilitate data interpretation was vocalized. Impacts on study behaviour varied, possibly because preparatory activities were not used. Impact could be improved by further integrating the LAD into existing learning processes.

Attentional guidance through object associations in visual cortex

Efficient behavior requires the rapid attentional selection of task-relevant objects. Preparatory activity of target-selective neurons in visual cortex is thought to support attentional selection, guiding spatial attention and favoring processing of target-matching input. However, naturalistic searches are often guided by nontargets, including target-associated “anchor” objects. For instance, when looking for a pen, we may direct our attention to the office desk on which we expect to find it. Here, using fMRI and eye tracking in a context-guided search task, we tested whether preparatory activity in visual cortex reflected the target, the guiding anchor object, or both. Participants learned associations between targets and anchors, reversing across two scene contexts, before searching for these targets. Participants’ first fixations were reliably guided by the associated anchor. Preparatory activity in lateral occipital cortex (LOC) and right intraparietal sulcus (IPS) represented the target-associated anchor rather than the target. These results shed light on the neural basis of context-guided search in structured environments.

Approaches to the Development of Student Groups in a Modern University: Team or Collective

The article is devoted to the issues of forming student groups in universities in modern conditions of the influence on young people of two opposing ideological trends: collectivism and individualism. The positive effects of collective education in the field of higher education are listed. Differences in the understanding of the terms “small group”, “work collective”, “team” and “team”, which have developed in the academic and business environment, are identified, from the point of view of value bases and group dynamics. The results of a diagnostic study of the adaptation of first-year students are presented, which allows us to draw a conclusion about the influence of the individualistic and collectivist strategy of integration into the group on the results of students’ adaptation. Options for scenarios for the formation of a group as a “collective” or as a “team” are proposed, which make it possible to differentiate approaches to pedagogical support for the development of student groups depending on the prevailing value systems of its members and the degree of readiness for collective action.

Implementasi Kurikulum Merdeka dalam Menumbuhkan Kemampuan Critical Thinking di Kelas XI F1 pada Mata Pelajaran Pendidikan Agama Islam di SMAN 8 Padang

This study aims to describe: 1) the planning of implementing the Merdeka Curriculum in fostering critical thinking skills in Class XI F1 for Islamic Religious Education subjects; 2) the implementation of the Merdeka Curriculum in developing critical thinking skills in Class XI F1 for Islamic Religious Education subjects; 3) the challenges and efforts faced by Islamic Religious Education teachers in nurturing critical thinking in Class XI F1 for Islamic Religious Education subjects. The research method used is qualitative with a descriptive approach. The results of the study show that, first, in the planning stage, teachers attended training, prepared teaching modules that included learning objectives, teaching models, learning activities, and assessment/evaluation. Second, the implementation involved preparatory activities such as preparing media/tools and motivating students in line with the Pancasila Student Profile. The core activities included activities 1.1, 1.2, and 1.3, while closing activities consisted of summarizing the lesson, reflecting, providing information about future learning, and concluding with a prayer. Third, the challenges faced by teachers included inadequate training and continued use of lecture-based methods. The efforts made to address these challenges included attending further training and mastering various teaching models.

Sports injury research of basketball specialized college students

Based on the investigation of basketball sports injury of the students in University, the questionnaire was collected, and the location and incidence rate of students in basketball were: finger(26.42%),ankle joint(22.54%),knee joint(11.92%),wrist(10.10%) and back(8.81%).The cause and incidence of damage are: to prepare activities(30.9%),to break the rules(25.13%), the technical error (19.43%),and the site(13.47%).Through literature review, interview method, mathematical statistics method, logical analysis method, the conclusion is that college students in basketball sports injury, because they do not seriously do the preparatory activities, technical differences, poor thinking, self-protection awareness, etc. Finally, some suggestions are put forward to reduce the student injury in basketball.

When preparation pays off.

Computational principles shed light on why movement is preceded by preparatory activity within the neural networks that control muscles.

Promoting women's wellbeing through the Niska (Goose) Harvesting Program in subarctic Ontario, Canada.

Geese harvesting is a longstanding cultural tradition deeply ingrained among the Omushkego Cree in Fort Albany First Nation, embodying a holistic approach to health that integrates Indigenous knowledge, community wellbeing, and resilience. Despite historical disruptions stemming from colonization and assimilation policies, women have played a pivotal role in preserving and passing down traditional practices. The significance of goose harvesting extends beyond providing a nutrient-rich and cost-effective food source; it serves as a vehicle for cultural preservation and education, particularly fostering language acquisition among children. Nevertheless, concerns persist regarding the potential decline in the transmission of Indigenous knowledge. The interruption of intergenerational knowledge transfer not only poses implications for overall wellbeing but also worsens historical trauma within the community. In response to these challenges, the Niska (goose) harvesting program was developed with an aim to revitalize community harvesting practices, with a specific focus on incorporating the perspectives of women, especially in the preparatory and smoking phases of the geese. Omushkego Cree women were approached to participate. The study was conducted during the spring of 2018, and employed photovoice and semi-structured interviews that explored the impact of geese preparatory activities on the health and wellbeing of Indigenous women. Major themes from the qualitative data included the importance of knowledge sharing, cultural continuity, healing, and the profound connection to the land. Women emphasized the value of sharing acquired knowledge, passing on traditions, and maintaining a connection to their cultural identity. Cultural continuity, depicted through intergenerational teachings and experiences, emerged as crucial for overall wellbeing. Participants spoke of the healing dynamics derived from engaging in traditional activities, highlighting the positive impact on physical, mental, emotional, and spiritual wellbeing. The land was identified as a central element in this healing process, representing more than just a physical space but an extension of home, contributing to a sense of peace and tranquility. The land became a medium for transmitting cultural teachings, shaping identity, and sustaining a subsistence lifestyle. The study emphasizes the importance of future research including more female youth participants to uncover specific challenges and strengths within this demographic. Overall, the Niska program demonstrates a comprehensive approach that intertwines cultural revitalization, community engagement, and holistic wellbeing, emphasizing the need for interventions that go beyond immediate challenges to create enduring positive impacts on Indigenous communities.

Applicable International Standardized Basis in Defining Data for Security Systems Development

Creating an intelligent security environment is one of the main trends in the activity of scientific organizations, where security technologies are a significant part of the product range. Organizations using these technologies, including critical infrastructure with built-in security systems, provide increased operational efficiency, guaranteeing readiness for action in emergency situations. For this purpose, standardized approaches are applied to determine the requirements for the development of security systems, according to the specifics of the organization, ensuring the prevention of any level of potential consequences of possible risk events, both in the structural objects of the organization and for the population in the adjacent territories. The author's intention is through this publication to present his experience in the application of modern standardized approaches ensuring the construction and operation of critical infrastructure security systems developed by scientific organizations in the conditions of key partnerships of the Competence Center.

The Effects of Persuasive Message Reading and Supportive Writing on Juveniles’ Readiness for Protective and Evasive Actions against Domestic Violence in the Community

Domestic violence has physical and psychological impacts, as well as a negative effect on the well-being of juveniles in the family. Hence, this experimental research explored the interaction between persuasive message reading, supportive writing, types of punishment, as well as well-being and the juveniles’ readiness for protective and evasive actions against domestic violence in the community. The research was based on a Post Test Only with Control Group Design, dividing into 4 experimental groups with random assignment. The sample was 450 juveniles in Northern communities within 3 provinces including Lamphun, Lampang, and Nan. The research instruments in this research consist of the articles of 1) persuasive message on “the readiness for protective and evasive actions against domestic violence” and 2) control message on “the importance of English learning” the worksheets of 1) supportive writing on “the readiness for protective and evasive actions against domestic violence” and 2) control writing on “the importance of English learning” the assessment on 1) types of punishment, 2) well-being, 3) the readiness for protective and evasive actions against domestic violence, and 4) biosocial background. For the 10-item well-being assessment, the range of t value = 4.27-7.39, the range of r value = 0.34-0.67, and reliability = 0.78. For the 15-item assessment on the readiness for protective and evasive actions against domestic violence, the range of t value = 5.32-9.21, the range of r value = 0.28-0.56, and reliability = 0.81.The findings revealed that 1)the juveniles who read persuasive messages, were physically punished, and rarely had a sense of well-being were readier to perform protective and evasive actions against domestic violence than the juveniles who did not read persuasive messages, were psychologically punished, and had a sense of well-being. This was mostly found among the juveniles who spent a lot of time with their families. 2) The juveniles who wrote supportive writing and rarely had a sense of well-being were readier to perform protective and evasive actions against domestic violence than the juveniles who did not write supportive writing and had a sense of well-being. This was mostly found among the juveniles who consulted other people. The results led to suggestions and practices to develop and encourage juveniles’ readiness for protective and evasive actions against domestic violence in the future.

Reduction in preparatory brain activity preceding gait initiation in individuals with chronic ankle instability: A movement-related cortical potential study.

Evidence suggests that chronic ankle instability (CAI) is not merely a peripheral musculoskeletal injury but should be recognized as a neurophysiological dysfunction. This reflects a paradigm shift from focusing on peripheral structural changes to emphasizing the central nervous system. However, changes in cortical activity during functional activities remain poorly understood. Thus, this study aimed to compare preparatory brain activity during gait initiation (GI) through movement-related cortical potentials (MRCPs) in individuals with CAI and healthy subjects. The proactive components of MRCPs, including contingent negative variation (CNV) and event-related desynchronization (ERD), were measured using electroencephalography. The primary outcomes were late CNV amplitude, CNV peak amplitude, CNV peak time, and alpha/beta ERD. The results indicated that the late CNV amplitude was significantly lower in the CAI group compared to the healthy group at the Fz and Cz electrodes (P< 0.001). The CAI group also demonstrated lower CNV peak amplitude at the Fz, Cz, and Pz electrodes (P< 0.0025). Additionally, in the CAI group, signals peaked earlier at the Cz electrode (P= 0.002). Furthermore, alpha ERD at Pz was significantly lower in the CAI group than in the healthy group (P= 0.003), suggesting diminished preparatory brain activity during GI in CAI subjects. Recognizing CAI as a condition involving both peripheral and central dysfunctions highlights the importance of a multidisciplinary approach in treatment and rehabilitation. This approach should target brain activity in addition to peripheral structures, potentially leading to improved long-term outcomes for patients.

Encoding of 2D Self-Centered Plans and World-Centered Positions in the Rat Frontal Orienting Field.

The neural mechanisms of motor planning have been extensively studied in rodents. Preparatory activity in the frontal cortex predicts upcoming choice, but limitations of typical tasks have made it challenging to determine whether the spatial information is in a self-centered direction reference frame or a world-centered position reference frame. Here, we trained male rats to make delayed visually guided orienting movements to six different directions, with four different target positions for each direction, which allowed us to disentangle direction versus position tuning in neural activity. We recorded single unit activity from the rat frontal orienting field (FOF) in the secondary motor cortex, a region involved in planning orienting movements. Population analyses revealed that the FOF encodes two separate 2D maps of space. First, a 2D map of the planned and ongoing movement in a self-centered direction reference frame. Second, a 2D map of the animal's current position on the port wall in a world-centered reference frame. Thus, preparatory activity in the FOF represents self-centered upcoming movement directions, but FOF neurons multiplex both self- and world-reference frame variables at the level of single neurons. Neural network model comparison supports the view that despite the presence of world-centered representations, the FOF receives the target information as self-centered input and generates self-centered planning signals.

Exploring the Nexus: Personality Disorders and Their Impact on Violent Extremism, Radicalism, and Activism.

The escalating global concerns surrounding radicalization and violent extremism necessitate a comprehensive understanding and explanation. Identifying the risk factors associated with radicalism and violent extremism is critical to the development of risk assessment, prevention, and intervention strategies. It is imperative to distinguish these risks from civic responsibilities (i.e., activism) to safeguard individual rights. This study aims to examine the association between well-established risk factors for violence-personality disorder symptoms-and violent extremist attitudes, radicalism, and activism. Findings indicate that antisocial personality disorder symptoms were linked to violent extremist attitudes and radicalism, whereas obsessive-compulsive disorder symptoms were related to activism. This suggests that obsessive-compulsive personality disorder may signify a readiness for legal and nonviolent political action; in contrast, antisocial personality disorder symptoms signify a readiness for extremist violence and illegal political action.

A new method for tracking the preparatory activation of target templates for visual search with high temporal precision.

Efficiently selecting task-relevant objects during visual search depends on foreknowledge of their defining characteristics, which are represented within attentional templates. These templates bias attentional processing toward template-matching sensory signals and are assumed to become anticipatorily activated prior to search display onset. However, a direct neural signal for such preparatory template activation processes has so far remained elusive. Here, we introduce a new high-definition rapid serial probe presentation paradigm (RSPP-HD), which facilitates high temporal resolution tracking of target template activation processes in real time via monitoring of the N2pc component. In the RSPP-HD procedure, task-irrelevant probe displays are presented in rapid succession throughout the period between task-relevant search displays. The probe and search displays are homologously formed by lateralized "clouds" of colored dots, yielding probes that occur at task-relevant locations without confounding template-guided and salience-driven attentional shifts. Target color probes appearing at times when a corresponding target template is active should attract attention, thereby eliciting an N2pc. In a condition where new probe displays appeared every 50 ms, probe N2pcs were reliably elicited during the final 800 ms prior to search display onset, increasing in amplitude toward the end of this preparation period. Analogous temporal profiles were also observed with longer intervals between probes. These findings show that search template activation processes are transient and that their temporal profile can be reliably monitored at high-sampling frequencies with the RSPP-HD paradigm. This procedure offers a new route to approach various questions regarding the content and temporal dynamics of attentional control processes.

Target switch costs in visual search arise during the preparatory activation of target templates.

Prior research on task switching has shown that the reconfiguration of stimulus-response mappings across trials is associated with behavioral switch costs. Here, we investigated the effects of switching representations of target-defining features in visual search (attentional templates). Participants searched for one of two color-defined target objects that changed predictably every two trials (Experiment 1) or every four trials (Experiment 2). Substantial costs were observed for search performance on target switch relative to target repeat trials. Preparatory target template activation processes were tracked by measuring N2pc components (indicative of attentional capture) to a rapid series of task-irrelevant color singleton probes that appeared during the interval between search displays, and either matched the currently relevant or the other target color. N2pcs to relevant target color probes emerged from 800 ms before search display onset on target repetition trials, reflecting the activation of a corresponding color template. Crucially, probe N2pcs only emerged immediately before target onset on target switch trials, indicating that preparatory template activation was strongly delayed. In contrast, irrelevant color singleton probes did not trigger N2pcs on either repeat or switch trials, suggesting the absence of any target template inertia across trials. These results show that switching the identity of search targets delays preparatory target template activation and impairs subsequent attentional guidance processes. They suggest that performance costs on switch versus repeat trials are associated with differences in the time course of task preparation.

Preparatory activity of anterior insula predicts conflict errors: integrating convolutional neural networks and neural mass models

Preparatory brain activity is a cornerstone of proactive cognitive control, a top-down process optimizing attention, perception, and inhibition, fostering cognitive flexibility and adaptive attention control in the human brain. In this study, we proposed a neuroimaging-informed convolutional neural network model to predict cognitive control performance from the baseline pre-stimulus preparatory electrophysiological activity of core cognitive control regions. Particularly, combined with perturbation-based occlusion sensitivity analysis, we pinpointed regions with the most predictive preparatory activity for proactive cognitive control. We found that preparatory arrhythmic broadband neural dynamics in the right anterior insula, right precentral gyrus, and the right opercular part of inferior frontal gyrus (posterior ventrolateral prefrontal cortex), are highly predictive of prospective cognitive control performance. The pre-stimulus preparatory activity in these regions corresponds to readiness for conflict detection, inhibitory control, and overall elaborate attentional processing. We integrated the convolutional neural network with biologically inspired Jansen-Rit neural mass model to investigate neurostimulation effects on cognitive control. High-frequency stimulation (130 Hz) of the left anterior insula provides significant cognitive enhancement, especially in reducing conflict errors, despite the right anterior insula’s higher predictive value for prospective cognitive control performance. Thus, effective neurostimulation targets may differ from regions showing biomarker activity. Finally, we validated our theoretical finding by evaluating intrinsic neuromodulation through neurofeedback-guided volitional control in an independent dataset. We found that left anterior insula was intrinsically modulated in real-time by volitional control of emotional valence, but not arousal. Our findings further highlight central role of anterior insula in orchestrating proactive cognitive control processes, positioning it at the top of hierarchy for cognitive control.