Previous studies have demonstrated that First Nations (FN) pregnant women urgently need feasible and culturally appropriate prenatal education. However, the prenatal class attendance rate is low in many FN communities, or the program is not active in some communities. Socioeconomic and geographic barriers have been identified as major underlying mechanism for the low access to prenatal education in rural-living FN pregnant women in Manitoba. Access to the internet and Facebook is widespread. We developed a Facebook-linked website, www.momsinmotion.ca, to deliver prenatal and breastfeeding in the communities. The content includes video/audio education on healthy eating, physical activity, diabetes/obesity prevention and breastfeeding promotion. The website was advertised through community radio/TV station and workshops in 3 FN communities. Pregnant women in the communities can sign up through internet to access the information 81/220 of pregnant women signed up for the e-education from the 3 FN communities from July, 2015 to December, 2016, which represented 37% of total pregnancies in the 3 FN communities. The prenatal education delivery rate was increased by 3 times (p<0.001) compared to that in 2011-13 in those communities (12%). Preterm birth and microsomia and macrosomia were reduced in the communities by 32%, 37% and 5% after the launch of e-education compared to that before, but the differences were not statistically different. In conclusion, e-education increases the participation of prenatal education of rural-living FN pregnant women and potentially improves neonatal outcomes in the communities.