Background: Despite numerous studies focusing on the burden of food insecurity, few have assessed its impact among sexual minority (LGB) populations. Sexual minority individuals are subject to chronic levels of stress, including stigma, prejudice, and discrimination as a result of their sexual orientation identity. While few studies have documented food insecurity among sexual minorities, the relationship between food insecurity and discrimination among this stigmatized population remains unclear. Aim: This study aimed to assess the toll of food insecurity among a sample of sexual minority men (i.e. bisexual and gay men) in the U.S. Guided by the Minority Stress Theory, the study also assessed the relationship between food insecurity and perceived discrimination. Methods: Researchers disseminated an online survey and recruited gay and bisexual men in the U.S. The survey collected participants' demographic information, perceived discrimination, and food insecurity. Multivariable logistic regression analyses were used to examine the association between perceived discrimination and food insecurity. Results: A total of 504 sexual minority men (49.2% bisexual and 50.8% gay) completed the survey. Results from logistic regression models suggest perceived discrimination was significantly associated with food insecurity (OR = 1.14, CI: 1.11-1.18). Those living with a partner demonstrated lower odds of food insecurity (OR = 0.38, CI: 0.18-0.71). Conclusion: The present study found a significant association between perceived discrimination and food insecurity among sexual minority men. The findings need to be replicated and further explored through additional research, including qualitative methods, to better elucidate how discrimination is related to experiences with food insecurity among gay and bisexual men.