Adult Preference Research Articles

Pubertal stress in male rats: Effects on juvenile play behavior and adult sexual partner preference

Puberty is a period of brain organization impacting the expression of social and sexual behaviors. Here, we assessed the effects of an acute pubertal stressor (immune challenge) on the expression of juvenile play (short-term) and sexual partner preference (long-term) in male rats. Juvenile play was assessed over ten trials at postnatal days (PND) (31–40) with age- and sex-matched conspecifics, and at PND35 males received a single injection of lipopolysaccharide (LPS, 1.5 mg/kg i.p.) or saline. Then, sexual partner preference was assessed at PND 60, 64, and 68, in a three-compartment chamber with a sexually receptive female and a male as potential partners simultaneously. The results confirmed that a single injection of LPS during puberty induced sickness signs indicative of an immune challenge. However, juvenile play was not affected by LPS treatment during the following days (PND36–40), nor was sexual behavior and partner preference for females in adulthood. These findings highlight that, while other studies have shown that LPS-induced immunological stress during puberty affects behavior and neuroendocrine responses, it does not affect juvenile play and sexual behavior in male rats. This suggests a remarkable resilience of these behavioral systems for adaptation to stressful experiences mediated by immune challenges during critical periods of development. These behaviors, however, might be affected by other types of stress.

Proxy Preferences and the Values of Children's Health States.

To assign values to the health states of children, some health economists have suggested relying on the 'proxy' preferences among the health states of children expressed by a random sample of the adult population. These preferences have been elicited in several ways, with respondents sometimes asked to express their (adult) preferences among the health states of children, and sometimes asked to imagine themselves as children and to express what they think their preferences would be. This essay discusses three grounds for eliciting the preferences of a random sample of adults that have been suggested as ways to assign values to the health states in the EQ-5D-Y, and criticizes the first two: (1) the evidential ground: the preferences of the population sample are good evidence of how good or bad the health states of children are; (2) the 'taxpayer' ground: the adult population has the authority to assign values to health states, therefore their preferences are determinative; and (3) the pragmatic grounds: surveying is straightforward and shifts the responsibility from health economists to the population. I argue that instead of surveying a random sample of the population, health economists should rely on deliberative groups that include older children, experts on children's health and development, as well as members of the population at large. These groups should engage with the reasons that lie behind preferences among health states.

Perspectives on sperm donor anonymity: insights from donor-conceived adults in Belgium.

Are donor-conceived adults in Belgium interested in obtaining donor information, and do these interests vary based on their family backgrounds? Donor-conceived adults express a significant interest in obtaining donor-related information, with the highest interest reported by offspring from heterosexual couples compared to those from lesbian couple-parented or single-parent families. In Belgium, sperm donation is mainly anonymous, but the rise of direct-to-consumer genetic testing challenges this anonymity. This was a cross-sectional study involving an online nationwide survey conducted from July 2022 to October 2023. Participants, aged 18years and older and being aware of their anonymous sperm donor-conceived status, were recruited through various channels. A total of 203 participants were included: 62.6% grew up in heterosexual families with infertile fathers, 26.1% with lesbian couples, 8.4% with single parents, and 3.0% in various or diverse family structures. The survey was available in both French and Dutch and consisted of 43 questions, including a mix of yes/no questions and multiple-choice items. The average age of disclosure was 16.5 years, with notably later disclosure in heterosexual couple-parented households. A substantial 82.8% of donor-conceived individuals expressed a keen interest in obtaining non-personally identifiable donor information, while 69% were curious about personally identifiable donor data. Furthermore, 61.6% conveyed a desire for personal contact with their donors, and 26.6% advocated for the inclusion of the donor's name on their birth certificates. Participants raised in lesbian two-parent families exhibited the lowest level of interest in donor-related information compared with those raised in other family structures. An overwhelming 90.1% wondered about the possibility of having half-siblings from the same sperm donor. Analysis of survey responses on DNA database registration revealed that 55.2% of donor-conceived offspring were already registered, with 68.8% discovering the same donor offspring and 30.4% successfully locating their donors. Compared to individuals from other family structures, those raised in heterosexual couple-parented households exhibit a less positive attitude toward their conception through anonymous sperm donation. About 61.6% of donor-conceived individuals reported experiencing distinct emotions compared to their peers, while 44.1% encountered psychological difficulties related to anonymous sperm donation, primarily attributed to late disclosure. The majority supported the idea of informing the donor about the number of children he facilitated to conceive. Lastly, the study highlighted that 21.2% of donor-conceived adults considered becoming donors themselves, and 31.3% expressed willingness to use an anonymous donor whenever faced with fertility challenges. Our sample size may not fully represent all adults conceived through anonymous sperm donation in Belgium. Participation bias may have influenced the results, especially due to the overrepresentation of participants from heterosexual couples. Additionally, an association exists between individuals raised by heterosexual couples and late disclosure, complicating the analysis by introducing a confounding factor. The findings of this study contribute to a better understanding of the needs and preferences of donor-conceived adults, with significant potential impact on patient education and healthcare policy. Study funding was not obtained for this research. There are no conflicts of interest to disclose. N/A.

Examining the concordance between dominant eye and hand preference in healthy adults

Examining the concordance between dominant eye and hand preference in healthy adults

Advance care planning behavioral intentions predict older adults’ cardiopulmonary resuscitation preferences

Whether to perform cardiopulmonary resuscitation (CPR) in emergencies is a critical discussion in advance care planning (ACP). Few studies have investigated the relationship between older adults’ ACP behavioral intention and CPR preferences. The study aimed to understand whether ACP behavioral intention predicts CPR preferences in older adults. Cross-sectional secondary data was applied. Two hundred twenty participants from two studies completed an ACP behavioral intention assessment and a cartoon version of the life support preferences questionnaire. Among the participants, 78 preferred CPR and 142 did not. Responses differed significantly by sex (X2 = 3.870, p = 0.049), age (X2 = 6.105, p = 0.013), and ACP behavioral intention (t = 2.933, p = 0.004). The logistic regression results indicated that older adults who tended to undertake ACP did not like to receive CPR (OR = 0.534, p = 0.035). ACP intervention methods should differ depending on CPR preference. Future research should develop ACP interventions for individuals with different CPR preferences.

Understanding the preferences of young adults with type 2 diabetes mellitus with regard to diabetes self-management education: a qualitative study

AimYoung-onset type 2 diabetes (YOD) is associated with poorer clinical outcomes. To support the development of more effective diabetes self-management education (DSME) programmes, this study aimed to understand the preferences...

Exploring Spice Consumption and Spice Taste Preferences in Adults: A Qualitative Study

Exploring Spice Consumption and Spice Taste Preferences in Adults: A Qualitative Study

University Students’ Engagement with Ulamas’ Political Messages on Social Media

Ulama involvement in educating the young generation about political issues is seen as crucial. However, their involvement's significance potentially diminishes with the increased accessibility of political information through digital media. This qualitative study utilises the Uses and Gratifications Theory as a valuable lens in exploring the engagement of university students in Sulawesi, Indonesia, with ulamas’ political lectures on social media. Thematic analysis of 101 eligible participant’s responses resulted in four key themes: da’wah preferences, content, styles, and impacts. Politics was not the primary or secondary topic preference for the young adults when engaging with Islamic lectures on social media. Instead, topics such as Islamic rituals and the life of the Prophet took precedence. Participants emphasised that ulamas maintained the balance between entertaining audiences and keeping online da’wah educating and relevant to the audience. Ulamas’ arguments in da’wah should be grounded in Islamic texts and prevent divisiveness in society. Students confirmed that their knowledge and attitudes towards important national or local issues were improved due to ulamas’ da’wah. Although students expressed a sense of powerlessness to address political issues highlighted in da’wah, some reported that da’wah motivated them to take action. This study underscores the importance of ulamas adjusting their da’wah approach to suit young audiences. Further research needs to explore strategies to enhance youth engagement with political content on social media. Keywords: Opinion leaders, ulama, political messages, da’wah, social media.

Host plant selection is linked to performance in Phthorimaea absoluta (Lepidoptera: Gelechiidae).

The evolution of oviposition preference in insects is considered a key evolutionary strategy in the context of host-plant interaction. It is hypothesized that insects maximize the survival and fitness of the subsequent generations by preferring specific host plant(s), known as the "preference-performance hypothesis." In this study, we tested whether adult host preference reflects the immature performance in an oligophagous insect, Phthorimaea absoluta Meyrick, a rapidly emerging invasive pest in Asia, Africa, and Europe. Based on a preliminary survey of the potential host plants of P. absoluta, we selected 6 Solanaceae species, namely, tomato, potato, eggplant, black nightshade, sweet pepper, and tobacco, for the oviposition preference studies. The results indicated that the tomato was the most preferred host in no-, dual- and multiple-choice assays, followed by potato, eggplant, and black nightshade. Subsequently, the insect life-table parameters were found to be superior on tomato compared to other hosts. The order of oviposition preference on the host plants was strongly correlated with the life-table parameters of P. absoluta. Thus, we provide clear evidence for the preference-performance hypothesis in the host selection behavior of P. absoluta. We also emphasize the necessity of conducting oviposition behavior research at various geographic locations to develop tailor-made integrated pest management programs.

Integrating linear and nonlinear models to assess the built environment’s impact on older adults’ behaviors in China

China is experiencing rapid population aging. The one contributing factor affecting senior citizens’ lives is the disconnect between the built environment in urban and rural areas and the behavioral preferences of older adults. However, research on the relation between the built environment and the behavior of older individuals has been limited. Thus, this paper uses the most recent health tracking data on factors influencing aging in China released in 2020 (China Senior Health Survey Tracking Survey). Applying traditional regression, least absolute shrinkage and selection operator regression, and two decision tree optimization models from machine learning, a comprehensive comparative study is carried out to investigate the correlation between the built environment and the physical activity, dietary habits, and social interactions of older age groups. The findings reveal that built environment variables most significantly impact physical activity, accounting for 52.525%, followed by social interaction behaviors at 50.202% and dietary intake at 47.991%. Furthermore, the authors identify population density and greenness rate as the built environment factors having considerable effects on the behavior of older adults. Thus, this study establishes a theoretical foundation for developing age-friendly community environments for older adults.

Corticosterone after early adolescent stress prevents social avoidance, aversive behavior, and morphine-conditioned place preference in adulthood.

Stress during childhood or adolescence increases vulnerability to psychiatric disorders in adults. In adult rodents, the delayed effects of stress can increase anxiety-like behavior. These effects, however, can be prevented with post-stress administration of corticosterone (CORT). The effectiveness of CORT in preventing adolescent stress-induced emotional behavior alterations in adulthood has yet to be investigated. Here, we investigated the interactions between early adolescent stress and exogenous corticosterone on adult social, aversive, and drug-seeking behavior in mice, which are translationally related to symptoms associated with psychiatric and substance abuse disorders. A single administration of CORT in drinking water (400ug/mL) for 24h after social defeat or context fear conditioning prevents defeat-induced social avoidance, alters fear processing, prevents adolescent stress-induced anhedonia, and prevents stress-potentiated morphine place preference in adulthood. Exogenous CORT did not immediately prevent stress-induced potentiation of morphine conditioned-place preference in adolescents but did so in adult mice. However, when administered to adolescent mice, CORT also prevented the incubation of morphine-conditioned place preference into adulthood. Lastly, exogenous CORT administration blunted endogenous corticosterone but was unrelated to freezing behavior during a fear test. This is the first demonstration of adolescent post-stress CORT promoting socio-emotional resilience and preventing drug-seeking behavior. Our data suggest elevated corticosterone after a stress experience promotes resilience for at least 40 days across the developmental transition from adolescence to adulthood and is effective for socio-emotional and drug-seeking behavior. These results are critical for understanding how adolescent stress impacts emotional and drug-seeking behavior into adulthood.

“Be more positive and more kind to your own bodies”: Adolescent and young adult preferences for how parents can support their children with weight-related pressures

Body dissatisfaction is a key factor contributing to the development of disordered eating, and body dissatisfaction is often influenced by media, peer, and parental pressures during adolescence. Little research has explored ways in which parents can help their children manage pressures from social media and their peers. The present study used the MyVoice National Poll of Youth, a large text-message cohort of young people (14–24 years old) in the United States, to collect and examine qualitative data about their experiences with parental weight-related communication and how they think parents can best support their children regarding messages they see/hear surrounding weight, body shape and size by their peers and media sources. 801 participants responsed to at least one question. Results from the present study suggest that young people want their parents to model healthy relationships with food and their body, teach body neutrality/acceptance, and normalize all body types. Findings suggest that there are many proactive, practical approaches parents can adopt to help support their children and offset weight-related pressures from other sources.

#783 Individualized net benefit of intensive blood pressure lowering among older adults in SPRINT

Abstract Background and Aims The optimal blood pressure (BP) target for older adults remains controversial. This study aimed to determine whether results from the Systolic Blood Pressure Intervention Trial (SPRINT) could be tailored to individual trial participants using risk estimates and simulated preferences about the relative importance of multiple outcomes related to BP lowering. Method This analysis included 4,850 SPRINT participants age ≥65 years. Parsimonious Cox models were internally validated to predict the absolute difference in risk between intensive versus standard BP lowering in each SPRINT participant for all-cause death, cardiovascular outcomes, cognitive outcomes, and serious adverse events. Treatment effects were combined using simulated preference weights into an individualized net benefit, which represents the weighted sum of risk differences across outcomes. Individualized net benefits among older SPRINT participants were compared across categories of age (65-74 years vs. ≥ 75 years), frailty (fit, less fit, and frail), and polypharmacy status. Results When simulating preferences for older adults who view death, cardiovascular events, and cognitive impairment as much more important than the harms of BP lowering, the median (IQR) individualized net benefit was 5% (3%, 7%), and 100% had a net benefit that favoured intensive BP lowering. When simulating benefits and harms to have similar importance, the median (IQR) individualized net benefit was 2% (1%, 3%), and 95.4% had a positive net benefit. In subgroup analyses, the predicted net benefit of intensive BP lowering was significantly greater among those with advanced age, frailty, and polypharmacy compared with lower risk individuals (P<0.001 for all comparisons). Conclusion Almost all older participants in SPRINT had a predicted net benefit that favoured intensive BP control, but the degree of net benefit varied considerably. Personalizing BP targets for older adults according to each person's estimated risks and preferences may provide more refined BP target recommendations.

Social activities in multidomain dementia prevention interventions: insights from practice and a blueprint for the future.

Social activities are important for health and act as a driver of cognitive reserve during aging. In this perspective paper, we describe challenges and outline future (research) endeavors to establish better operationalization of social activities in multidomain interventions to prevent dementia. We first address the lack of conceptual clarity, which makes it difficult to measure engagement in social activities. Second, drawing from our experience with the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER), we discuss social activities in multidomain dementia prevention interventions. Using qualitative data from the Multimodal Preventive Trial for Alzheimer's Disease (MIND-ADmini), we reflect on participant experiences with social activities. Third, we address the potential and challenges of digital solutions in promoting social activities in interventions for dementia prevention. Finally, we share insights from a workshop on digital technology, where we consulted with individuals with and without cognitive impairment who have been involved in three European projects (i.e., EU-FINGERS, Multi-MeMo, and LETHE). Based on these insights, we advocate for research that strengthens and accelerates the integration of social activities into multidomain interventions for dementia prevention. We propose several ways to achieve this: (a) by conducting mixed methods research to formulate a broadly accepted definition and instructions to measure social activities; (b) by focusing on promoting engagement in social activities beyond the intervention setting; and (c) by exploring the needs and preferences of older adults towards digitally-supported interventions and co-design of new technologies that enrich in-person social activities.

Understanding housing preferences and challenges of older adults in Kalisz, Poland

Purpose: This study aimed to identify the demographic, economic, and social factors that influence the housing demand of older adults in Kalisz, Poland, and assess their preferences and challenges in meeting their housing needs. Methodology: A quantitative survey was conducted among individuals aged 50 and above in Kalisz. The survey questionnaire covered various aspects, including current housing conditions, housing preferences, knowledge of senior housing options, and willingness to relocate to such housing. Data analysis involved descriptive statistics and correlation analysis. Results: The findings revealed that while most respondents were satisfied with their current housing situation, they acknowledged the need for housing options tailored to older adults. However, there was a lack of interest in relocating to designated senior housing due to concerns about affordability, accessibility, and amenities. Respondents expressed a preference for independent living arrangements with access to medical, care, and rehabilitation services. Theoretical contribution: The study contributes to the understanding of the housing needs and preferences of older adults in the context of a medium-sized city in Poland. It highlights the importance of considering demographic shifts and adapting housing policies and urban planning strategies to meet the diverse requirements of an aging population. Practical implications: The findings can inform policymakers, urban planners, and housing developers in designing and implementing housing solutions that cater to the specific needs of older adults, ensuring accessible, affordable, and supportive living environments. The study also emphasizes the need for public awareness and education regarding senior housing options.

Urinary Incontinence in Active Female Young Adults: Healthcare Preferences, Priorities and Experiences

Introduction and HypothesisThere is a paucity of evidence on the healthcare preferences of active female young adults with urinary incontinence (UI). This research is aimed at examining the population’s healthcare preferences and priorities and their characteristics and experiences to improve access to and use of services.MethodsThis cross-sectional online survey study used a convenience community sample. Participants resided in Australia, were 18–30 years old, had self-reported engagement in physical activity of any frequency and self-reported urine leakage in the previous 4 weeks and met other eligibility criteria. Data were analysed using descriptive analyses.ResultsThirty-nine participants took part in the study. The majority engaged in recreational exercise (74.2%) and experienced UI of slight to moderate severity (82.9%). Participants preferred to access information and support anonymously online (71.4%) from general practitioners (58.8%), medical specialists (50.0%) or physiotherapists (44.1%). All participants wanted to be involved in the UI management decision-making process. Participants prioritised knowing information over cost (38.2%), changes to daily habits (35.3%) and potential risks or side effects (23.5%) when making decisions about management of UI.ConclusionThe results highlight the diversity among active female young adults with UI. They emphasise the need for shared decision making and highlight key information needs, providing the basis for the development of decision-making tools and protocols specific to this population. They demonstrate the need for anonymous online information and support, and draw attention to the presence of UI among young recreational exercisers, highlighting the importance of ensuring that information and support is available within this demographic.

A Personalized and Interactive Web-Based Advance Care Planning Intervention for Older Adults (Koda Health): Pilot Feasibility Study.

Advance care planning (ACP) is a process that involves patients expressing their personal goals, values, and future medical care preferences. Digital applications may help facilitate this process, though their use in older adults has not been adequately studied. This pilot study aimed to evaluate the reach, adoption, and usability of Koda Health, a web-based patient-facing ACP platform, among older adults. Older adults (aged 50 years and older) who had an active Epic MyChart account at an academic health care system in North Carolina were recruited to participate. A total of 2850 electronic invitations were sent through MyChart accounts with an embedded hyperlink to the Koda platform. Participants who agreed to participate were asked to complete pre- and posttest surveys before and after navigating through the Koda Health platform. Primary outcomes were reach, adoption, and System Usability Scale (SUS) scores. Exploratory outcomes included ACP knowledge and readiness. A total of 161 participants enrolled in the study and created an account on the platform (age: mean 63, SD 9.3 years), with 80% (129/161) of these participants going on to complete all steps of the intervention, thereby generating an advance directive. Participants reported minimal difficulty in using the Koda platform, with an overall SUS score of 76.2. Additionally, knowledge of ACP (eg, mean increase from 3.2 to 4.2 on 5-point scale; P<.001) and readiness (eg, mean increase from 2.6 to 3.2 on readiness to discuss ACP with health care provider; P<.001) significantly increased from before to after the intervention. This study demonstrated that the Koda Health platform is feasible, had above-average usability, and improved ACP documentation of preferences in older adults. Our findings indicate that web-based health tools like Koda may help older individuals learn about and feel more comfortable with ACP while potentially facilitating greater engagement in care planning.

PERSPECTIVES OF PEOPLE WITH CHRONIC KIDNEY DISEASE REGARDING DIGITAL HEALTH INTERVENTIONS THAT PROMOTE A HEALTHY LIFESTYLE: QUALITATIVE SYSTEMATIC REVIEW

Chronic kidney disease (CKD) is a life-limiting condition that affects 1 in 10 adults and accounts for 12% of all deaths in Australia. Diet and physical activity are crucial to attenuate disease progression and reduce mortality risk. Digital health interventions have been proposed as a feasible model to deliver lifestyle interventions. Users’ perspectives are key to ensure the intervention is aligned with their needs and goals. As such, this systematic review aimed to synthesise the perspectives of people with CKD and develop higher order concepts that elucidate users’ preferences regarding digital health interventions that promote heathy lifestyle. This was a qualitative systematic review. A database search was conducted on CENTRAL, Scopus, MEDLINE, CINAHL and SPORTDiscus between 2000-2023. Eligibility criteria included primary research that reported the preferences of adults with CKD regarding digital lifestyle interventions. Two independent reviewers completed title, abstract and full text screening. Quotes were extracted verbatim, coded and categorised. Categories were then used to generate themes. Database search identified 5,761 records. One additional record was included following communication with a primary author. Fifteen papers were eligible, including 197 participants (age 51.0±7.2 years; 47% female). There were 83 people with CKD 1-5; 61 transplant recipients; and 53 people receiving maintenance dialysis. The overarching theme identified was that people with CKD considered digital interventions to be important platforms to access lifestyle interventions. There were five underlying themes that elucidated users’ preferences for digital interventions, including simple instruction and engaging design; individualised interventions; virtual communities of care; education and action plans; and timely reminders and automated behavioural monitoring. Digital health interventions were considered important platforms to deliver lifestyle interventions. Future research may apply users’ preferences in this review to inform the development and conduct of a digital lifestyle intervention for people with CKD.

Preferences of people with chronic kidney disease regarding digital health interventions that promote healthy lifestyle: qualitative systematic review with meta-ethnography

ObjectivesDiet and physical activity are crucial for people with chronic kidney disease (CKD) to maintain good health. Digital health interventions can increase access to lifestyle services. However, consumers’ perspectives are...

Older adults preferences for long-term caregivers in China: a discrete choice experiment

ObjectiveUnderstanding the preferences of old-age adults for their long-term caregivers can improve person-centred health care and the quality of long-term care (LTC). This study examines Chinese older adults’ preferences for long-term caregivers. Study designThis is a cross-sectional study. MethodsA national representative discrete choice experiment (DCE) surveyed 2031 adults aged 50–70 across 12 provinces in China. Each DCE scenario described five attributes: type of caregivers, place of LTC, contents of LTC, out-of-pocket payments, and quality of life (QoL). Preferences and the marginal willingness to pay (WTP) were derived using mixed-logit and latent class models. ResultsOlder adults displayed higher preferences for long-term caregivers who improve their QoL, incur lower out-of-pocket payments, and provide medical LTC services at home, with the maximum WTP of $22.832 per month. QoL was rated as the most important LTC factor, followed by the place of LTC and the type of caregivers. When the level of QoL improved from poor to good, respondents would be willing to pay $18.375 per month more (95% confidence interval: 16.858 to 20.137), and the uptake rate increased by 76.47%. There was preference heterogeneity among older people with different sex, education, family size, and knowledge of LTC insurance. ConclusionQoL was the most important factor in older Chinese adults' preference for caregivers. Home care and medical care from formal caregivers was preferred by older adults. We recommend training family caregivers, raising older people's awareness of LTC insurance, and guiding policymakers in developing people-oriented LTC and a multi-level LTC system.