Abstract This study was performed to investigate the relations between internet addiction, depression, and anxiety in smoking adolescents. In order to get the data by self-questionnaire, 202 subjects were selected from Aug. 15 to Sep. 20, 2012. The data was analyzed by mean, standard deviation, t-test, ANOVA, Pearson’s correlation coefficient, and multiple regression using SPSS/WIN 18.0 program. Internet addiction score was 30.9±6.55, depression score was 9.0±4.76, and anxiety score was 12.3±5.31. There were significant positive correlations between internet addiction and depression, between internet addiction and anxiety, between depression and anxiety. Multiple regression analysis revealed that the predictors of internet addiction were average number of days drinking alcohol per month, average daily cigarette consumption and starting daily smoking age. The findings of study will be used for basic information to prevent and control internet addiction of smoking adolescents. Key Words :