Adolescent Predictors Research Articles

Trust to the Mother Among Adolescents From Single-Parent Families and the Structure of Its Predictors

The scientific and psychological validity of the a priori attitude of practicing psychologists and parents in solving the urgent problem of adolescent distrust has been verified that the trusting attitude of adolescents towards parents exists only in the form of opposition; trust or distrust based on a previously developed model for studying ambivalent trust. The aim of the research was to study the features of the classified ratios of trust/distrust to a mother in adolescents from single-parent families and the role of order in the structure of predictors of trust in a mother in these ratios. The study involved adolescent boys and girls, in the number of 177 people aged 15 years, raised in families where the only parent living with a teenager is the mother. The following methods were used: content analysis based on expert assessments; subjective scaling according to specified parameters; statistical technology for developing the construct classification of the trust/distrust ratio; approximation by hyperbolic rank parametric distribution; nonparametric statistics. It was found that 1) only 19% of the respondents have “absolute trust” and “absolute distrust”, and the rest have different variants of ambivalent trust (p<0.01). 2) significant predictors of adolescents trust in the mother are: a) “trust in me”; b) honesty; c) reliability; d) fairness; e) commitment to fulfilling promises; f) an unappreciative attitude. 3) the average value of the β coefficient is higher in the “positive” variant of ambivalent trust, when adolescents from single-parent families have both trust and distrust of their mother, but trust significantly prevails over distrust.

Tracking adolescent students’ educational pathways to university through school engagement, parental expectations, and student aspirations

Although improvements have been made in terms of enhancing the number of students that enrol in higher education, the long-term educational pathways of adolescents to university studies are understudied. This calls for further research into the mechanisms that underpin the long-term educational pathways of adolescents who study at university versus those who do not. The present study examines an innovative model that tracks adolescents’ educational pathways to university in England through the developmental dynamics of emotional school engagement, parental educational expectations, and adolescent aspirations. The data came from 9173 adolescents (51.63% female) from six waves of the Next Steps cohort study in England. The data were analysed using longitudinal structural equation modelling and cross-lagged panel modelling. The results of random-intercept cross-lagged panel modelling revealed positive within-person reciprocal relations between emotional engagement, parental educational expectations, and adolescent university aspirations only between specific ages. Latent regression analysis showed that greater levels of sustained parental expectations, emotional school engagement, and adolescent university aspirations were linked to greater likelihood of pursuing university-entrance exams (A-Levels, age 17). Sustained engagement had only an indirect effect on university attendance via university-entrance exams and educational persistence (age 18). Sustained high parental educational expectations were the most direct and robust predictor of adolescents’ university attendance. The findings underscore a synergistic effect between sustained parental expectations, emotional school engagement, and adolescent university aspirations as the mechanisms that lead adolescents to university studies.

Interpersonal Stressors Predicting Inflammation in Adolescents: Moderation by Emotion Regulation and Heart Rate Variability?

This study assessed interpersonal stressors (peer adversity and parental rejection) as predictors of adolescents’ circulating inflammatory markers, while examining emotion regulation and parasympathetic nervous system activity (at rest, reactivity, and recovery) as potential protective moderators. Data were collected in a Belgian cohort of adolescents in 2017 (n=185, 51.4% boys, 10-18y) and 2018 (n=98), and included serum inflammatory markers (CRP, TNFα, IFNγ, IL-6, IL-8 and IL-10), peer adversity, parental rejection, emotion regulation and heart rate variability (RMSSD-HRV, at rest and in 2018 also in response to a Trier Social Stress Test). Contrary to the hypothesis, interpersonal stressors were negatively related to TNFα (in 2017 and 2018), IFNγ (in 2017 and longitudinally) and IL-6 (in 2018). In 23% of the tested associations, HRV at rest was a significant moderator: the negative stressor-inflammation associations were present only among adolescents with low HRV resting values. No significant moderation by HRV reactivity or recovery was detected. After correction for multiple testing, all above-mentioned significant findings disappeared. These unexpected findings may suggest that the positive association between stress exposure and circulating markers of inflammation is not yet detectable in adolescence and perhaps becomes evident only later in life.

From Counting Dollars to Counting Sheep: Exploring Simultaneous Change in Economic Well-Being and Sleep among African American Adolescents.

In the U.S.A., Black/African American adolescents disproportionately experience short and poor-quality sleep, and there is little understanding of why some experience decrements or improvements in sleep over time. Toward conducting culturally specific research and identifying processes that uniquely explain variability within a racial/ethnic group, we utilized a within-group design to examine socioeconomic status (SES) as a predictor of Black adolescents' sleep. Few studies have examined change-on-change processes in sleep over time. Contributing to the literature in novel ways, we assessed the predictive effect of change in SES over one year on changes in four actigraphy-derived sleep parameters over the same time period. Participants were 218 Black adolescents (Time 1: Mage = 17.09 years; 54.6% female) and their mothers from socioeconomically diverse backgrounds. Adolescents participated in two-waves of data collection spaced approximately one year apart. At each wave, we assessed economic well-being (used to index SES) and sleep using 7 nights of actigraphy from which we derived measures of sleep duration (minutes) and quality (efficiency, long-wake episodes, activity). Latent difference score analyses revealed that adolescents experiencing increases in SES over one year exhibited decreases in both long-wake episodes and sleep activity over one year. Findings suggest that individual differences in change in SES explain individual differences in change in adolescents' sleep quality. Notably, findings highlight the utility of within-group designs for identifying culturally specific processes that predict improvements in sleep quality in a sample at disproportionate risk for sleep and health disparities.

Parenting Styles as Predictors of Adolescents’ Susceptibility to Peer Pressure in Secondary Schools in Anambra State, Nigeria

This study examined the relationship among the four levels of parenting styles and peer pressure among senior secondary school Adolescents in Anambra State, Nigeria. Six research questions and saix hypotheses guided the study. The design of the study was correlational research design. The population comprised 55,696 adolescents in senior secondary schools in Anambra State. A sample size of 1,000 senior secondary school students were selected through proportionate stratified and convenience sampling techniques. The research instrument that was used in the study is a validated and reliable questionnaire. Multiple regression statistics was used to test hypotheses 1-5 while the Fisher-z statistics were used to test hypothesis 6. The hypotheses were tested at 0.05 level of significance. The findings of the study revealed that there is a significant relationship between four parenting styles and peer pressure among senior secondary school Adolescents; that there is a significant relationship between authoritative parenting style and peer pressure among senior secondary school Adolescents; that there is a significant relationship between authoritarian parenting style and peer pressure among senior secondary school Adolescents; that there is a significant relationship between permissive parenting style and peer pressure among senior secondary school Adolescents; and that there is a significant relationship between neglecting parenting style and peer pressure among senior secondary school Adolescents. The study however, revealed that there is no significant moderating impact of sex in the relationship between parenting styles and peer pressure among senior secondary school Adolescents in Anambra State. On the basis of these findings, it was recommended amongst others, that Guidance counsellors should provide parenting workshops and resources that educate parents on the different parenting styles and the importance of fostering open communication, clear expectations, and warmth in the parent-child relationship, regardless of the specific style used.

Leisure activities, substance use and psychological health among Hungarian adolescents

ABSTRACT During the past several decades, adolescents’ leisure has undergone several important changes due to, for example, alternative modes of entertainment, such as video gaming and social media which have had a significant influence on their well-being. The aim of this study was to examine the relationships of adolescents’ leisure activities to their substance use and psychological health. Participants were middle and high school students (N = 2,239, aged between 12 and 18 years, M = 14.61 years, SD = 1.71; 51.8% females) using data drawn from the Szeged Youth Study 2022, Hungary. Peer-based leisure was positively associated with all types of substance use. Playing and gaming leisure showed a negative relationship with psychosomatic and depressive symptomatology. Aesthetic-sophisticated and family-based leisure proved the most beneficial for psychological health and health behaviour, and it was also the strongest predictor of adolescents’ life satisfaction. Arts, hobbies and internet use played a beneficial role.

The Triple E project: a factorial randomised controlled trial to enhance engagement with eHealth approaches to improve health risk behaviours among adolescents

BackgroundDigital, or eHealth, interventions are highly promising approaches to help adolescents improve their health behaviours and reduce their risk of chronic disease. However, they often have low uptake and retention. There is also a paucity of high-quality research into the predictors of eHealth engagement, and a lack of studies that have systematically evaluated existing engagement strategies in adolescent populations. This paper describes the protocol for a randomised controlled trial which primarily aims to assess the effectiveness of different strategies in increasing engagement with a healthy lifestyles app, Health4Life. Associations between the engagement strategies and improvements in adolescent health behaviours (healthy eating, physical activity, sleep, recreational screen time, smoking, alcohol use) will also be examined, along with potential predictors of adolescents’ intentions to use health apps and their use of the Health4Life app.MethodsThe current study will aim to recruit 336 adolescent and parent/guardian dyads (total sample N = 672) primarily through Australia wide online advertising. All adolescent participants will have access to the Health4Life app (a multiple health behaviour change, self-monitoring mobile app). The trial will employ a 24 factorial design, where participants will be randomly allocated to receive 1 of 16 different combinations of the four engagement strategies to be evaluated: text messages, access to a health coach, access to additional gamified app content, and provision of parent/guardian information resources. Adolescents and parents/guardians will both complete consent processes, baseline assessments, and a follow-up assessment after 3 months. All participants will also be invited to complete a qualitative interview shortly after follow-up. The primary outcome, app engagement, will be assessed via an App Engagement Index (Ei) using data collected in the Health4Life app and the Mobile App Rating Scale – User version.DiscussionThis research will contribute significantly to building our understanding of the types of strategies that are most effective in increasing adolescents’ engagement with health apps and which factors may predict adolescents’ use of health apps.Trial registrationThe trial is registered at the Australian New Zealand Clinical Trials Registry (ACTRN12623000399695). Date registered: 19/04/2023.

Predictive relationship between COVID-19 anxiety and psychological distress in adolescents during the COVID-19 pandemic.

COVID-19 was a novel stressor that gave rise to pandemic related anxiety and increased the risk of mental health issues, particularly in youth. It is important to understand how such events contribute to psychological distress in young people to adequately intervene in the aftermath and to plan for future similar events. Using cross-sectional data from the CoSPACE Ireland study dataset this paper reports on the predictive relationship between COVID-19 anxiety and psychological distress for Irish adolescents (N = 314, M = 14.05, SD = 2.7, 11-18 years), while controlling for other influencing factors across multiple levels of a bioecological systems approach. Covariates were age, gender, ethnicity, social economic status, Peer Support, School Support and Parent-Child Closeness. Findings indicate that COVID-19 anxiety was a significant predictor of adolescents' psychological distress. Specifically, Consequence Anxiety (worries about the indirect consequences of COVID-19) was found to be a predictor of adolescents' psychological distress rather than Disease Anxiety (worries about the COVID-19 virus itself). Individual factors (e.g., age, ethnicity, special educational needs) and microsystem factors (e.g., parent child closeness, peer support) were also found to impact on adolescents' levels of psychological distress. A significant moderation analysis revealed that greater parent-child closeness reduced the strength of the positive association between Consequence Anxiety and psychological distress. These findings suggest that strategies to alleviate adolescents' psychological distress during pandemics should focus on reducing pandemic-related anxiety, specifically Consequence Anxiety. A multisystemic approach is also recommended to reduce the negative mental health impacts of the pandemic on adolescents.

Adolescent predictors of substance use in young adulthood among individuals with childhood-onset chronic pain: Afollow-up study.

Adolescent chronic pain is a substantial public health problem, and pain symptoms often persist into adulthood. Young adults with chronic pain are at elevated risk for more frequent tobacco, alcohol and cannabis use, and cross-sectional research highlights the importance of psychosocial vulnerability factors. Limited research has examined how adolescent predictors, including mental health symptoms, pain, sleep and family functioning, impact later, young adult substance use. A prospective cohort of 229 young adults (77.3% female; Mage = 21.0, SD = 1.6) with childhood-onset chronic pain completed measurements in adolescence and a follow-up assessment in young adulthood of past 3-month substance use frequency. Adolescent sleep quality and male sex were associated with more frequent tobacco use; adolescent depression was associated with more frequent alcohol use, and adolescent pain severity was associated with less frequent, and male sex was associated with more frequent cannabis use. Adolescent predictors of young adult substance use among youth with childhood-onset chronic pain represent important factors that may inform assessment, prevention and treatment of substance use in this population. Identifying and testing psychological interventions that target these vulnerability factors may reduce overall substance use risk in young adulthood. This prospective observational study of young adults with childhood-onset chronic pain identified adolescent depression and sleep quality as vulnerability factors associated with substance use. Given the increasing risk for substance use during adolescence and young adulthood, these findings highlight the potential importance of early intervention to reduce substance use among young adults with childhood-onset chronic pain.

Machine learning approach to investigate pregnancy and childbirth risk factors of sleep problems in early adolescence: Evidence from two cohort studies

BackgroundThis study aimed to predict early adolescent sleep problems using pregnancy and childbirth risk factors through machine learning algorithms, and to evaluate model performance internally and externally. MethodsData from the China Jintan Child Cohort study (CJCC; n=848) for model development and the US Healthy Brain and Behavior Study (HBBS; n=454) for external validation were employed. Maternal pregnancy histories, obstetric data, and adolescent sleep problems were collected. Several machine learning techniques were employed, including least absolute shrinkage and selection operator, logistic regression, random forest, naïve bayes, extreme gradient boosting, decision tree, and neural network. The area under the receiver operating characteristic curve, sensitivity, specificity, accuracy, and root mean square of residuals were used to evaluate model performance. ResultsKey predictors for CJCC adolescents’ sleep problems include gestational age, birthweight, duration of delivery, and maternal happiness during pregnancy. In HBBS adolescents, the duration of postnatal depressive emotions was the primary perinatal predictor. The prediction models developed in the CJCC had good-to-excellent internal validation performance but poor performance in predicting the sleep problems in HBBS adolescents. ConclusionThe identification of specific perinatal risk factors associated with adolescent sleep problems can inform targeted interventions during and after pregnancy to mitigate these risks. Health providers should consider integrating these predictive factors into routine pre- and postnatal assessments to identify at-risk populations. The variability in model performance across different cohorts highlights the need for context-specific models and the cautious application of predictive analytics across diverse populations. Future research should focus on refining predictive models to account for such variations, potentially through the incorporation of additional socio-cultural factors and genetic markers. This study emphasizes the importance of personalized and culturally sensitive approaches in the prediction and management of adolescent sleep problems, leveraging advanced computational methods to enhance maternal and child health outcomes.

Early Mother-Child Interaction Flexibility Predicts Adolescent Psychological Adjustment.

Although greater mother-child interaction flexibility has been linked with overall better adjustment within early childhood and adolescence, whether this link persists across the two developmental periods remains unknown. This longitudinal study examined mother-toddler flexibility in affective and behavioral exchanges as predictors of adolescents' externalizing and internalizing symptoms. Sample included 128 families with their 33-month-old toddlers (52% female), of whom 67 returned in adolescence (M age = 13.25 years, SD = 0.59). Greater affective flexibility during play and behavioral flexibility during snack predicted fewer parent-reported externalizing (but not internalizing) symptoms ten years later, controlling for the positivity-negativity of mother-toddler interactions, early-childhood adjustment, and mother-adolescent flexibility. The findings highlight the unique, prospective role of early-life caregiving flexibility in mitigating adolescents' behavioral problems.

Young Adult Career Outcomes for Adolescents With ADHD, High Ability, or Twice-Exceptionality

The purpose of this study was to explore career outcomes in young adulthood among adolescents with ADHD and/or high abilities. The sample included respondents who had the ability and ADHD measures from Waves 1 (1995), 3 (2002), and 4 (2009) of the National Longitudinal Study of Adolescent and Adult Health in-home questionnaire. Using multiple group path analysis, we examined the pathways for three groups of individuals (i.e., ADHD, high ability, and both/twice-exceptional). We discovered financial and educational family background predicted occupational status and career goal attainment, as well as supports and barriers among various family and adolescent predictors (e.g., school attachment, educational aspiration, depressive symptoms). Knowledge about these trajectories will help professionals design tailored career and educational services for adolescents with high ability, ADHD, and both.

Physical Activity Behaviors of Female Adolescents in Saudi Arabia.

Saudi Arabia has one of the highest childhood obesity rates worldwide. The primary factor associated with the high prevalence of obesity among adolescents is a lack of physical activity (PA). Compared to male adolescents, very few Saudi female adolescents meet the World Health Organization recommendation of achieving 60 minutes of moderate-to-vigorous PA per day, putting them at a higher risk of overweight and obesity. This cross-sectional study aimed to examine the relationship between the theory of planned behavior and psychosocial factors, including attitude toward PA, subjective norms, perceived behavioral control (PBC), PA intention, and self-reported PA among Saudi female adolescents. A convenience sample of 329 Saudi female adolescents was recruited from all-female public intermediate and high schools in the Eastern Region of Saudi Arabia. Data were collected using online self-administered questionnaires. The theoretical model was examined using structural equation modeling. The findings revealed a higher prevalence of overweight compared to obesity among participants. About half the participants were from families with a medium monthly income. The mean PA score indicated a low level of PA. The model demonstrated significant explanatory power for both PA intention and PA behavior, respectively. The strongest predictor of adolescents' intention was attitude, followed by PBC.Moreover, the female adolescents' attitudes and PBC had significant indirect effects on self-reported PA through intention, whereas intention had a direct effect on PA. The model did not support a direct or indirect relationship between subjective norms and PA. The findings provide essential support for targeting attitude and perceived behavior control of female adolescents in order to enhance their PA intention. This theoretical understanding can help design effective theory-based interventions that promote PA among Saudi female adolescents.

Intention to quit or reduce e-cigarettes, cannabis, and their co-use among a school-based sample of adolescents

IntroductionLittle is known about the prevalence and predictors of adolescents’ intention to quit or reduce use of e-cigarettes and/or cannabis. MethodsFrequencies of intention to change (quit, reduce) e-cigarettes and/or cannabis use were examined among 23,915 surveyed middle and high school students with sole and co-use. Predictors of intention to change were identified via LASSO/multilevel logistic regression. ResultsAmong those with sole e-cigarette use (n = 543), 40.9 % intended to quit and 24.1 % intended to reduce; non-daily e-cigarette use predicted intention to quit and reduce e-cigarettes (p’s < 0.03). Among those with sole cannabis use (n = 546), 10.6 % intended to quit and 25.1 % intended to reduce; absence of cannabis cravings predicted intention to reduce cannabis use (p < 0.01). Among those with co-use (n = 816), 26.2 % intended to either quit or reduce (quit/reduce) both substances, 27.5 % intended to quit/reduce e-cigarettes only, and 6.9 % intended to quit/reduce cannabis only. No predictors emerged for intention to change e-cigarette use among those with co-use (p’s > 0.09), but younger age, lack of poly-tobacco use, and lack of cannabis craving predicted intention to quit/reduce cannabis use (p’s < 0.04). ConclusionsMore than half of adolescents with past-month e-cigarette use, regardless of concurrent cannabis use, expressed interest in changing their use. However, only heaviness of e-cigarette use emerged as a predictor of intention to change suggesting. While fewer students expressed interest in changing their cannabis use, cannabis cravings and poly-tobacco use predicted intent to change. Overall, findings emphasize the need to tailor interventions towards adolescents engaging in more problematic substance use patterns.

A Model for Explaining Digital Addiction in Adolescents: The Role of Self-Perception, Social-Emotional Learning, Adolescent-Parent Relationship and Peer Relationships

Objective: This study was aimed at examining the levels of digital addiction in adolescents with a regression model created with self-perception, adolescent-parent relationships, peer relationships, and social-emotional learning (SEL) skills. &#x0D; Method: The participants consisted of 504 high school students. The data were obtained through the Personal Information Form, the Digital Addiction Scale, the Adolescent-Parent Relationships Scale, the Friendship Quality Scale, the Self-Perception Scale, and the Social and Emotional Learning Scale. &#x0D; Results: Self-perception, adolescent-parent relationship, and SEL skills were significant predictors of adolescents' digital addiction levels, while the peer relationships was not. Additionally, the regression model explains approximately 27% of the total variance of digital addiction in adolescents.&#x0D; Conclusion: The ability of digital platforms to compensate for negative self-perception during adolescence, coupled with inadequate SEL skills, may hinder adolescents from forming satisfying real relationships with themselves and their environment, ultimately increasing their levels of digital addiction. In families without satisfying relationships with parents where there is no positive, warm, supportive, and safe climate, this may cause digital addiction in adolescents.

Addressing the Sleep Deprivation Epidemic in Adolescents: Findings from the Youth Risk Behavior Survey 2021

ABSTRACT Background Millions of U.S. youths do not get adequate sleep. Healthy People 2030 has prioritized sleep and identified an objective to increase the proportion of students in grades 9 through 12 who get sufficient sleep. Purpose This study investigated the predictors of severe sleep deprivation in adolescents. Methods Data were obtained from the 2021 Youth Risk Behavior Survey (YRBS), a school-based survey, conducted by the Centers for Disease Control (CDC). Severe sleep deprivation was defined as 6 hours or less sleep per night on school nights. Binary logistic regressions were used to estimate the associations. Results Among the 17,232 youth surveyed, 48.2% experienced severe sleep deprivation. Self reported overweight and poor mental health status, limited physical activity, excessive screen time, smoking/vaping, lacking school connectedness, parental monitoring, school, and neighborhood safety as well as not having stable housing were statistically significant predictors of adolescents’ severe sleep deprivation. Discussion Scaling up sleep health programs in schools, neighborhoods, and subpopulations of adolescents could be a fundamental step toward achieving health equity. Translation to Health Education Practice Educators, health professionals, and social workers should be informed about the risk and protective factors of sleep health, and adolescents’ vulnerabilities to sleep deprivation.

Adolescent predictors of young adult pain and health outcomes: results from a 6-year prospective follow-up study.

Adolescent chronic pain may lead to persistent disability and long-term health impairments in adulthood. However, our understanding of which youth are more likely to experience adverse outcomes remains limited. To address this gap, this longitudinal cohort study examined adolescent predictors of various dimensions of young adult health and functioning, including pain, physical health, depression, anxiety, social isolation, and sleep disturbance. As part of a previous clinical trial, we recruited a cohort of adolescents (ages 11-17 years, M age = 14 years) with non-disease-related chronic pain from 15 tertiary pain clinics in North America. Approximately 6 years later, 229 of the original 273 individuals (81% participation rate) completed a follow-up survey as young adults (ages 18-25 years, M age = 21 years). At the young adult follow-up, 73% reported continued chronic pain, with two-thirds experiencing moderate-to-severe pain interference. Youth reported several adverse health outcomes, including below-average physical health (37%), clinically elevated depression (42%), clinically elevated anxiety (48%), and sleep disturbances (77%). Multivariate regression analyses controlling for sociodemographic characteristics revealed that higher pain intensity, more pain locations, lower sleep quality, and greater anxiety symptoms in adolescence predicted worse pain outcomes in young adulthood. Moreover, lower sleep quality, greater anxiety symptoms, and worse family functioning predicted worse physical and psychosocial health in adulthood. These findings represent an important first step toward identifying ways to optimize psychological pain interventions. Tailored psychological pain interventions can directly target adolescent vulnerabilities, including mood, sleep, and family risk factors, with the potential to disrupt a lifelong trajectory of pain and suffering.

Scholastic achievement among adolescents: Role of unique aspects of home and school conditions

Students generally consider scholastic achievement to be the grade they receive after a period of specific instruction. Researchers evaluate a person's scholastic achievement based on the knowledge and skills they have developed in the academic domain, as well as the test results they have obtained. Scholastic achievement is one of the critical parameters to measure affluence; therefore, researchers are keen to investigate the various dimensions that are going to affect it directly or indirectly. The present study focuses on analyzing the distinct dimensions of the home and school environment that show a direct association with adolescents' scholastic achievement. The study uses a correlational research design. This study has selected a sample of 154 individuals from the Delhi region of India. The results obtained through correlation and regression analysis clearly indicate that control and rejection in school settings, along with a permissive home environment, significantly predict the scholastic achievement of female adolescents. The results also revealed that a permissive, protective, and punishing home environment, as well as restrictions imposed in a school setting, are significant predictors of male adolescents' scholastic achievement. From this, it can be concluded that the home environment and school environment dimensions play a pivotal role in the attainment of scholastic achievement among adolescents.

Prevalence and early-life predictors of adverse childhood experiences: Longitudinal insights from a low-income country

BackgroundA sizeable literature shows that adverse childhood experiences (ACEs) are associated with poor health outcomes in later life. However, most studies on the prevalence and predictors of ACEs have been carried out in high-income countries using cross-sectional approaches. ObjectiveThe present study explores the prevalence and predictors of ACEs in Malawi, a low-income country, using prospective longitudinal data collected on adolescents. ParticipantsWe use data on 1375 adolescents and their biological mothers from the Malawi Longitudinal Study of Families and Health (MLSFH). ACEs were reported by adolescents over two survey waves, in 2017–18 and 2021. Predictors were reported by mothers in 2008 and 2010. MethodsMultivariate ordinary least square and logistic regression analyses of ACEs exposure reported by adolescents on indicators of family arrangements and resources. ResultsAdolescents report having been exposed to nearly seven ACEs on average. Among indicators of family arrangements and resources, the only significant predictors of cumulative ACEs exposure are polygyny (linked to parental absence) and mother's SF-12 mental health score (linked to physical abuse and witnessing domestic violence). ConclusionsACEs are much more prevalent in the low-income country under study than in middle- and high-income countries surveyed in prior research. Despite adversity being widespread, most indicators of family arrangements and resources highlighted in prior studies are not associated with adolescents' cumulative ACEs exposure in this context. Mothers' mental health in childhood nevertheless emerges as a significant predictor of adolescents' self-reported ACEs. These findings inform efforts aimed at preventing ACEs in high-adversity contexts.

C-reactive protein (CRP) in high altitude Bolivian peri-urban adolescents varies by adiposity, current illness, height, socioeconomic status, sex, and menarcheal status: The potential benefits and costs of adipose reserves in arduous environments.

In non-industrialized and low-income populations, adipose stores can serve as a valuable buffer against harsh conditions such as seasonal food scarcity. However, these reserves may incur costs due to adipocytes' production of pro-inflammatory cytokines; inflammation is associated with increased risk for cardiometabolic diseases later in life. Life history theory posits that, especially in populations with high juvenile mortality, higher adiposity may nonetheless be advantageous if its benefits in early life outweigh its later costs. Relatively little is known about adolescents' C-reactive protein concentration (CRP; an inflammation biomarker) in such environments. We investigated CRP and its associations with several hypothesized predictors in adolescents in an economically diverse peri-urban Andean community. We measured CRP in dried blood spots and collected data on anthropometrics, illnesses, socioeconomic status (SES), and menarcheal status in 59 female and 40 male adolescents ("Alteños", 11.0-14.9 years old) with normal vital signs in El Alto, Bolivia (~4150 m amsl). We used Cole's LMS method to standardize all anthropometrics for sex and age, and principal components analysis to construct a "fat-factor" variable loading on these standardized z-scores. We used multiple linear regression to assess the influence of fat-factor and other likely predictors on CRP rank. Compared to a national Bolivian growth reference, Alteños were, on average, shorter and leaner; only 6% were classified as overweight and none were obese. Pre-menarche females were on average leaner than post-menarche females. The best-fitting model explained 24% of the variance in CRP rank. Significant predictors were fat-factor, SES, current illness for males and pre-menarche females, and z-height for females. Our results are consistent with a tradeoff between investments in growth versus immune functioning, as might be expected in an environment with limited resources and high pathogen exposure (e.g., soil-transmitted helminths, poor sanitation). Thinner Alteños appear to maintain a minimum CRP concentration independent of fat-factor, while fatter (or less-thin) Alteños' CRP rises with fat-factor. Female Alteños appear to be trading off investment in immune response for investment in growth and maturation. Alteños' high rate of stunting and absence of obesity suggests chronic, presumably multifactorial, stress. Adipose stores likely buffer against some of these stressors and, in an environment such as this-in which many lack sufficient nutritious foods, potable water, adequate sewage, and health care-may confer a net lifetime benefit.