Cotton farmers in the Mississippi River Delta area typically apply preemergence and directed post emergence herbicides to a 400 to 500 mm (16 to 20 in.) band over the row, and then cultivate the middles without getting very close to the row. This project demonstrates that farmers can reduce the band width to 200 mm (8 in.) and then cultivate close to the row using precision-guided cultivators. Using this method, herbicide costs were reduced $30.22/ha ($12.23/acre) in 1992 and $27.80/ha ($11.25/acre) in 1993 with no differences in weed control or loss of yield. The total cost reduction taking into account the costs of cultivation and application was $25.60/ha ($10.36/acre) in 1992 and $25.77/ha ($10.43/acre) in 1993. Reducing the amount of herbicide used also reduces environmental risks. The precision guidance systems are affordable and easy to use.