Precise Image Segmentation Research Articles

MSMCNet: Differential context drives accurate localization and edge smoothing of lesions for medical image segmentation

Medical image segmentation plays a crucial role in clinical assistance for diagnosis. The UNet-based network architecture has achieved tremendous success in the field of medical image segmentation. However, most methods commonly employ element-wise addition or channel merging to fuse features, resulting in smaller differentiation of feature information and excessive redundancy. Consequently, this leads to issues such as inaccurate lesion localization and blurred boundaries in segmentation. To alleviate these problems, the Multi-scale Subtraction and Multi-key Context Conversion Networks (MSMCNet) are proposed for medical image segmentation. Through the construction of differentiated contextual representations, MSMCNet emphasizes vital information and achieves precise medical image segmentation by accurately localizing lesions and enhancing boundary perception. Specifically, the construction of differentiated contextual representations is accomplished through the proposed Multi-scale Non-crossover Subtraction (MSNS) module and Multi-key Context Conversion Module (MCCM). The MSNS module utilizes the context of MCCM coding and redistribute the value of feature map pixels. Extensive experiments were conducted on widely used public datasets, including the ISIC-2018 dataset, COVID-19-CT-Seg dataset, Kvasir dataset, as well as a privately constructed traumatic brain injury dataset. The experimental results demonstrated that our proposed MSMCNet outperforms state-of-the-art medical image segmentation methods across different evaluation metrics.

An Approach for Plant Leaf Image Segmentation Based on YOLOV8 and the Improved DEEPLABV3.

Accurate plant leaf image segmentation provides an effective basis for automatic leaf area estimation, species identification, and plant disease and pest monitoring. In this paper, based on our previous publicly available leaf dataset, an approach that fuses YOLOv8 and improved DeepLabv3+ is proposed for precise image segmentation of individual leaves. First, the leaf object detection algorithm-based YOLOv8 was introduced to reduce the interference of backgrounds on the second stage leaf segmentation task. Then, an improved DeepLabv3+ leaf segmentation method was proposed to more efficiently capture bar leaves and slender petioles. Densely connected atrous spatial pyramid pooling (DenseASPP) was used to replace the ASPP module, and the strip pooling (SP) strategy was simultaneously inserted, which enabled the backbone network to effectively capture long distance dependencies. The experimental results show that our proposed method, which combines YOLOv8 and the improved DeepLabv3+, achieves a 90.8% mean intersection over the union (mIoU) value for leaf segmentation on our public leaf dataset. When compared with the fully convolutional neural network (FCN), lite-reduced atrous spatial pyramid pooling (LR-ASPP), pyramid scene parsing network (PSPnet), U-Net, DeepLabv3, and DeepLabv3+, the proposed method improves the mIoU of leaves by 8.2, 8.4, 3.7, 4.6, 4.4, and 2.5 percentage points, respectively. Experimental results show that the performance of our method is significantly improved compared with the classical segmentation methods. The proposed method can thus effectively support the development of smart agroforestry.

From coarse to fine: a deep 3D probability volume contours framework for tumour segmentation and dose painting in PET images.

With the increasing integration of functional imaging techniques like Positron Emission Tomography (PET) into radiotherapy (RT) practices, a paradigm shift in cancer treatment methodologies is underway. A fundamental step in RT planning is the accurate segmentation of tumours based on clinical diagnosis. Furthermore, novel tumour control methods, such as intensity modulated radiation therapy (IMRT) dose painting, demand the precise delineation of multiple intensity value contours to ensure optimal tumour dose distribution. Recently, convolutional neural networks (CNNs) have made significant strides in 3D image segmentation tasks, most of which present the output map at a voxel-wise level. However, because of information loss in subsequent downsampling layers, they frequently fail to precisely identify precise object boundaries. Moreover, in the context of dose painting strategies, there is an imperative need for reliable and precise image segmentation techniques to delineate high recurrence-risk contours. To address these challenges, we introduce a 3D coarse-to-fine framework, integrating a CNN with a kernel smoothing-based probability volume contour approach (KsPC). This integrated approach generates contour-based segmentation volumes, mimicking expert-level precision and providing accurate probability contours crucial for optimizing dose painting/IMRT strategies. Our final model, named KsPC-Net, leverages a CNN backbone to automatically learn parameters in the kernel smoothing process, thereby obviating the need for user-supplied tuning parameters. The 3D KsPC-Net exploits the strength of KsPC to simultaneously identify object boundaries and generate corresponding probability volume contours, which can be trained within an end-to-end framework. The proposed model has demonstrated promising performance, surpassing state-of-the-art models when tested against the MICCAI 2021 challenge dataset (HECKTOR).

LMU-Net: lightweight U-shaped network for medical image segmentation.

Deep learning technology has been employed for precise medical image segmentation in recent years. However, due to the limited available datasets and real-time processing requirement, the inherently complicated structure of deep learning models restricts their application in the field of medical image processing. In this work, we present a novel lightweight LMU-Net network with improved accuracy for medical image segmentation. The multilayer perceptron (MLP) and depth-wise separable convolutions are adopted in both encoder and decoder of the LMU-Net to reduce feature loss and the number of training parameters. In addition, a lightweight channel attention mechanism and convolution operation with a larger kernel are introduced in the proposed architecture to further improve the segmentation performance. Furthermore, we employ batch normalization (BN) and group normalization (GN) interchangeably in our module to minimize the estimation shift in the network. Finally, the proposed network is evaluated and compared to other architectures on publicly accessible ISIC and BUSI datasets by carrying out robust experiments with sufficient ablation considerations. The experimental results show that the proposed LMU-Net can achieve a better overall performance than existing techniques by adopting fewer parameters.

Denoised encoder-based residual U-net for precise teeth image segmentation and damage prediction on panoramic radiographs

ObjectivesThis research focuses on performing teeth segmentation with panoramic radiograph images using a denoised encoder-based residual U-Net model, which enhances segmentation techniques and has the capacity to adapt to predictions with different and new data in the dataset, making the proposed model more robust and assisting in the accurate identification of damages in individual teeth. MethodsThe effective segmentation starts with pre-processing the Tufts dataset to resize images to avoid computational complexities. Subsequently, the prediction of the defect in teeth is performed with the denoised encoder block in the residual U-Net model, in which a modified identity block is provided in the encoder section for finer segmentation on specific regions in images, and features are identified optimally. The denoised block aids in handling noisy ground truth images effectively. ResultsProposed module achieved greater values of mean dice and mean IoU with 98.90075 and 98.74147 ConclusionsProposed AI enabled model permitted a precise approach to segment the teeth on Tuffs dental dataset in spite of the existence of densed dental filling and the kind of tooth. Clinical SignificanceThe proposed model is pivotal for improved dental diagnostics, offering precise identification of dental anomalies. This could revolutionize clinical dental settings by facilitating more accurate treatments and safer examination processes with lower radiation exposure, thus enhancing overall patient care.

UcUNet: A lightweight and precise medical image segmentation network based on efficient large kernel U-shaped convolutional module design

In recent years, precise medical image segmentation methods based on the encoder–decoder structure have attracted much attention, but there are still some limitations. They mainly manifest in two aspects: one is that the network structure becomes increasingly complex in pursuit of segmentation accuracy, and the other is the insufficient multiscale information fusion ability between the encoder and decoder. To address these issues, we designed a novel lightweight precise medical image segmentation network called UcUNet, which has not only a very large receptive field and multiscale information fusion ability but also a low parameter count. Specifically, we first designed an efficient U-shaped convolution module that can increase the network depth with fewer parameters and effectively filter out invalid features while fusing shallow and deep features. Furthermore, we ingeniously introduced large-kernel convolution into this module, which significantly improved the network’s receptive field with very few parameters, providing new ideas for the use of large-kernel convolution in lightweight models. In addition, we designed a self-adjusting multiscale feature fusion module based on large-kernel convolution to replace the original simple skip connections, effectively enhancing the network’s multiscale information extraction and fusion ability. Finally, we conducted experiments on multiple datasets, and the results showed that our method can achieve precise medical image segmentation with a low parameter count.

COMA-Net: Towards generalized medical image segmentation using complementary attention guided bipolar refinement modules

Precise medical image segmentation is a crucial step for proper isolation of target regions, such as an organ or lesion for accurate medical diagnosis, prognosis and certain medical procedures. Taking advantage of the available annotated medical image datasets, many CNN-based approaches have been proposed for segmentation over the years. These conventional approaches lack appropriate supervised means to enhance the foreground/target regions relative to background at the feature level for improving the generalizability of these methods to obtain better performance across diverse imaging modalities. In this work, we introduce COMA-Net (COMplementary Attention guided bipolar refinement-based Network), which employs a complementary attention scheme between a pair of positive and negative refinement modules placed on top of two encoder structures for generating refined feature references for the decoder stage in a supervised manner. A four-way feature shifting operation is introduced in conjunction with a set of dilated convolutional layers so that it considers the spatial relationships across a wider footprint leading to better contextual feature extraction. We also formulate a novel Foreground-to-Background Ratio (FBR) index to highlight the differences in signal power between target region and background due to the refinement. Experimental results on five different publicly available medical image segmentation datasets, including BUSI, GLAS, ISIC-2018, MoNuSeg and CVC-ClinicDB reveal that on average, the proposed method can achieve an additional mean F1, IoU, precision, and recall score of +0.97%, +1.25%, +1.11%, and +0.22%, respectively over the state-of-the-art segmentation methods, suggesting its great potential for application on real-world patient image data.

RetiFluidNet: A Self-Adaptive and Multi-Attention Deep Convolutional Network for Retinal OCT Fluid Segmentation.

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies on a precise image segmentation step. As manual analysis of retinal fluids is a time-consuming, subjective, and error-prone task, there is increasing demand for fast and robust automatic solutions. In this study, a new convolutional neural architecture named RetiFluidNet is proposed for multi-class retinal fluid segmentation. The model benefits from hierarchical representation learning of textural, contextual, and edge features using a new self-adaptive dual-attention (SDA) module, multiple self-adaptive attention-based skip connections (SASC), and a novel multi-scale deep self-supervision learning (DSL) scheme. The attention mechanism in the proposed SDA module enables the model to automatically extract deformation-aware representations at different levels, and the introduced SASC paths further consider spatial-channel interdependencies for concatenation of counterpart encoder and decoder units, which improve representational capability. RetiFluidNet is also optimized using a joint loss function comprising a weighted version of dice overlap and edge-preserved connectivity-based losses, where several hierarchical stages of multi-scale local losses are integrated into the optimization process. The model is validated based on three publicly available datasets: RETOUCH, OPTIMA, and DUKE, with comparisons against several baselines. Experimental results on the datasets prove the effectiveness of the proposed model in retinal OCT fluid segmentation and reveal that the suggested method is more effective than existing state-of-the-art fluid segmentation algorithms in adapting to retinal OCT scans recorded by various image scanning instruments.

CCTrans: Improving Medical Image Segmentation with Contoured Convolutional Transformer Network

Medical images contain complex information, and the automated analysis of medical images can greatly assist doctors in clinical decision making. Therefore, the automatic segmentation of medical images has become a hot research topic in recent years. In this study, a novel architecture called a contoured convolutional transformer (CCTrans) network is proposed to solve the segmentation problem. A dual convolutional transformer block and a contoured detection module are designed, which integrate local and global contexts to establish reliable relational connections. Multi-scale features are effectively utilized to enhance semantic feature understanding. The dice similarity coefficient (DSC) is employed to evaluate experimental performance. Two public datasets with two different modalities are chosen as the experimental datasets. Our proposed method achieved an average DSC of 83.97% on a synapse dataset (abdominal multi-organ CT) and 92.15% on an ACDC dataset (cardiac MRI). Especially for the segmentation of small and complex organs, our proposed model achieves better segmentation results than other advanced approaches. Our experiments demonstrate the effectiveness and robustness of the novel method and its potential for real-world applications. The proposed CCTrans network offers a universal solution with which to achieve precise medical image segmentation.

A Novel Approach for Diabetic Retinopathy Screening Using Asymmetric Deep Learning Features

Automatic screening of diabetic retinopathy (DR) is a well-identified area of research in the domain of computer vision. It is challenging due to structural complexity and a marginal contrast difference between the retinal vessels and the background of the fundus image. As bright lesions are prominent in the green channel, we applied contrast-limited adaptive histogram equalization (CLAHE) on the green channel for image enhancement. This work proposes a novel diabetic retinopathy screening technique using an asymmetric deep learning feature. The asymmetric deep learning features are extracted using U-Net for segmentation of the optic disc and blood vessels. Then a convolutional neural network (CNN) with a support vector machine (SVM) is used for the DR lesions classification. The lesions are classified into four classes, i.e., normal, microaneurysms, hemorrhages, and exudates. The proposed method is tested with two publicly available retinal image datasets, i.e., APTOS and MESSIDOR. The accuracy achieved for non-diabetic retinopathy detection is 98.6% and 91.9% for the APTOS and MESSIDOR datasets, respectively. The accuracies of exudate detection for these two datasets are 96.9% and 98.3%, respectively. The accuracy of the DR screening system is improved due to the precise retinal image segmentation.

PreciseEdge raster RGB image segmentation algorithm reduces user input for livestock digital body measurements highly correlated to real-world measurements.

Computer vision is a tool that could provide livestock producers with digital body measures and records that are important for animal health and production, namely body height and length, and chest girth. However, to build these tools, the scarcity of labeled training data sets with uniform images (pose, lighting) that also represent real-world livestock can be a challenge. Collecting images in a standard way, with manual image labeling is the gold standard to create such training data, but the time and cost can be prohibitive. We introduce the PreciseEdge image segmentation algorithm to address these issues by employing a standard image collection protocol with a semi-automated image labeling method, and a highly precise image segmentation for automated body measurement extraction directly from each image. These elements, from image collection to extraction are designed to work together to yield values highly correlated to real-world body measurements. PreciseEdge adds a brief preprocessing step inspired by chromakey to a modified GrabCut procedure to generate image masks for data extraction (body measurements) directly from the images. Three hundred RGB (red, green, blue) image samples were collected uniformly per the African Goat Improvement Network Image Collection Protocol (AGIN-ICP), which prescribes camera distance, poses, a blue backdrop, and a custom AGIN-ICP calibration sign. Images were taken in natural settings outdoors and in barns under high and low light, using a Ricoh digital camera producing JPG images (converted to PNG prior to processing). The rear and side AGIN-ICP poses were used for this study. PreciseEdge and GrabCut image segmentation methods were compared for differences in user input required to segment the images. The initial bounding box image output was captured for visual comparison. Automated digital body measurements extracted were compared to manual measures for each method. Both methods allow additional optional refinement (mouse strokes) to aid the segmentation algorithm. These optional mouse strokes were captured automatically and compared. Stroke count distributions for both methods were not normally distributed per Kolmogorov-Smirnov tests. Non-parametric Wilcoxon tests showed the distributions were different (p< 0.001) and the GrabCut stroke count was significantly higher (p = 5.115 e-49), with a mean of 577.08 (std 248.45) versus 221.57 (std 149.45) with PreciseEdge. Digital body measures were highly correlated to manual height, length, and girth measures, (0.931, 0.943, 0.893) for PreciseEdge and (0.936, 0. 944, 0.869) for GrabCut (Pearson correlation coefficient). PreciseEdge image segmentation allowed for masks yielding accurate digital body measurements highly correlated to manual, real-world measurements with over 38% less user input for an efficient, reliable, non-invasive alternative to livestock hand-held direct measuring tools.

A Deep Learning-Based Diagnosis System for COVID-19 Detection and Pneumonia Screening Using CT Imaging

Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a global threat impacting the lives of millions of people worldwide. Automated detection of lung infections from Computed Tomography scans represents an excellent alternative; however, segmenting infected regions from CT slices encounters many challenges. Objective: Developing a diagnosis system based on deep learning techniques to detect and quantify COVID-19 infection and pneumonia screening using CT imaging. Method: Contrast Limited Adaptive Histogram Equalization pre-processing method was used to remove the noise and intensity in homogeneity. Black slices were also removed to crop only the region of interest containing the lungs. A U-net architecture, based on CNN encoder and CNN decoder approaches, is then introduced for a fast and precise image segmentation to obtain the lung and infection segmentation models. For better estimation of skill on unseen data, a fourfold cross-validation as a resampling procedure has been used. A three-layered CNN architecture, with additional fully connected layers followed by a Softmax layer, was used for classification. Lung and infection volumes have been reconstructed to allow volume ratio computing and obtain infection rate. Results: Starting with the 20 CT scan cases, data has been divided into 70% for the training dataset and 30% for the validation dataset. Experimental results demonstrated that the proposed system achieves a dice score of 0.98 and 0.91 for the lung and infection segmentation tasks, respectively, and an accuracy of 0.98 for the classification task. Conclusions: The proposed workflow aimed at obtaining good performances for the different system’s components, and at the same time, dealing with reduced datasets used for training.

Towards an early diagnosis of Alzheimer disease: a precise and parallel image segmentation approach via derived hybrid cross entropy thresholding method

Towards an early diagnosis of Alzheimer disease: a precise and parallel image segmentation approach via derived hybrid cross entropy thresholding method

Incorporating global multiplicative decomposition and local statistical information for brain tissue segmentation and bias field estimation

Medical image is a cornerstone of modern healthcare providing unique diagnostic. However, intensity nonuniformity is quite often found in medical images and unavoidably poses many challenges for precise image segmentation. In this paper, we present an incorporating global multiplicative decomposition and local statistical information level set technique for tissue segmentation and bias estimation that handles both high noise and intensity nonuniformity. An image can be factored into two multiplicative parts (namely, bias-free image and bias field), which are used to capture global intensity statistics. At the same time, our technique considers statistical information with not only the mean but also the variance. Pixel intensity generally fluctuates around its mean in a local region. The variance can adjust the disagreement of each pixel to its mean, and is explored to overcome the effects of intensity nonuniformity. Finally, the level set energy formulation is in the form of the global multiplicative decomposition and local statistical information. To verify the availability of our technique, we have thoroughly experimented on composite and real images. Our techniques are also applied to the lesion regions of brains. Experimental results display that our technique can segment different kinds of images with high noise and intensity nonuniformity more accurately, and outperforms other solutions in comparison.

Image segmentation with Kapur, Otsu and minimum cross entropy based multilevel thresholding aided with cuckoo search algorithm

Color image segmentation is the primary factor to provide the intended information from the input image. The straightforward method called multilevel thresholding (MLT) is used to analyse the various classes of complex images. But, when the level of threshold increases, computational difficulty increases. Hence, MLT with most promising objective functions such as Kapur, Otsu and minimum cross entropy aided with cuckoo search algorithm (CSA) is used. The efficient metaheuristic cuckoo search algorithm’s controlling parameter balances the local and global search. In this paper, the efficacy of CSA at 4,5,6 and 7 threshold levels with various fitness functions are utilized for precise image segmentation. It is seen from experimental results, the Otsu based cuckoo search algorithm outperform than Kapur and MCE. Quality metrices such as computational time, PSNR (peak signal to noise ratio) and SSIM (structural similarity index) authenticate the exploration and exploitation capability of CSA algorithm for real-world applications.

Different methods of permeability calculation in digital twins of tight sandstones

The development of tight hydrocarbon resources has a significant impact on the future of the energy market. Digital Rock Physics (DRP) is technically recognized as an effective method for characterizing reservoir rock properties. However, there is uncertainty about what result the user-defined chain of Digital Image Processing (DIP) and Pore-Scale Simulation (PSS) will produce when applying DRP. The uncertainty surrounding this technology faces even a greater deal in tight formations where a considerable portion of pores are sub-resolved and cannot explicitly be seen in the reconstructed micro-scale x-ray Computed Tomography (μxCT) images.Regarding the μxCT images of Achimovskiy formation, which is classified as a tight sandstone resource, the addressed uncertainty has been evaluated based on various scenarios of well-known DIP and PSS approaches. The results show that image processing and segmentation impact on the absolute permeability values stronger than calculation methods. Furthermore, the cross-plot analysis shows that simple image processing and segmentation indicate the same trend as precise image processing and segmentation. The generated results for the studied formation show that if the experimental open porosity of a core sample is higher than 5%, μxCT images could feasibly resolve the system of connected pores.

AEDCN-Net: Accurate and Efficient Deep Convolutional Neural Network Model for Medical Image Segmentation

Image segmentation was significantly enhanced after the emergence of deep learning (DL) methods. In particular, deep convolutional neural networks (DCNNs) have assisted DL-based segmentation models to achieve state-of-the-art performance in fields critical to human beings, such as medicine. However, the existing state-of-the-art methods often use computationally expensive operations to achieve high accuracy and lightweight networks often lack a precise medical image segmentation. Therefore, this study proposes an accurate and efficient DCNN model (AEDCN-Net) based on an elaborate preprocessing step and a resourceful model architecture. The AEDCN-Net exploits bottleneck, atrous, and asymmetric convolution-based residual skip connections in the encoding path that reduce the number of trainable parameters and floating point operations (FLOPs) to learn feature representations with a larger receptive field. The decoding path employs the nearest-neighbor based upsampling method instead of a computationally resourceful transpose convolution operation that requires an extensive number of trainable parameters. The proposed method attains a superior performance in both computational time and accuracy compared to the existing state-of-the-art methods. The results of benchmarking using four real-life medical image datasets specifically illustrate that the AEDCN-Net has a faster convergence compared to the computationally expensive state-of-the-art models while using significantly fewer trainable parameters and FLOPs that result in a considerable speed-up during inference. Moreover, the proposed method obtains a better accuracy in several evaluation metrics compared with the existing lightweight and efficient methods.

FSS-2019-nCov: A deep learning architecture for semi-supervised few-shot segmentation of COVID-19 infection

The newly discovered coronavirus (COVID-19) pneumonia is providing major challenges to research in terms of diagnosis and disease quantification. Deep-learning (DL) techniques allow extremely precise image segmentation; yet, they necessitate huge volumes of manually labeled data to be trained in a supervised manner. Few-Shot Learning (FSL) paradigms tackle this issue by learning a novel category from a small number of annotated instances. We present an innovative semi-supervised few-shot segmentation (FSS) approach for efficient segmentation of 2019-nCov infection (FSS-2019-nCov) from only a few amounts of annotated lung CT scans. The key challenge of this study is to provide accurate segmentation of COVID-19 infection from a limited number of annotated instances. For that purpose, we propose a novel dual-path deep-learning architecture for FSS. Every path contains encoder–decoder (E-D) architecture to extract high-level information while maintaining the channel information of COVID-19 CT slices. The E-D architecture primarily consists of three main modules: a feature encoder module, a context enrichment (CE) module, and a feature decoder module. We utilize the pre-trained ResNet34 as an encoder backbone for feature extraction. The CE module is designated by a newly introduced proposed Smoothed Atrous Convolution (SAC) block and Multi-scale Pyramid Pooling (MPP) block. The conditioner path takes the pairs of CT images and their labels as input and produces a relevant knowledge representation that is transferred to the segmentation path to be used to segment the new images. To enable effective collaboration between both paths, we propose an adaptive recombination and recalibration (RR) module that permits intensive knowledge exchange between paths with a trivial increase in computational complexity. The model is extended to multi-class labeling for various types of lung infections. This contribution overcomes the limitation of the lack of large numbers of COVID-19 CT scans. It also provides a general framework for lung disease diagnosis in limited data situations.

Optic disc and optic cup segmentation based on anatomy guided cascade network

Background and ObjectiveGlaucoma, a worldwide eye disease, may cause irreversible vision damage. If not treated properly at an early stage, glaucoma eventually deteriorates into blindness. Various glaucoma screening methods, e.g. Ultrasound Biomicroscopy (UBM), Optical Coherence Tomography (OCT), and Heidelberg Retinal Scanner (HRT), are available. However, retinal fundus image photography examination, because of its low cost, is one of the most common solutions used to diagnose glaucoma. Clinically, the cup-to-disk ratio is an important indicator in glaucoma diagnosis. Therefore, precise fundus image segmentation to calculate the cup-to-disk ratio is the basis for screening glaucoma. MethodsIn this paper, we propose a deep neural network that uses anatomical knowledge to guide the segmentation of fundus images, which accurately segments the optic cup and the optic disc in a fundus image to accurately calculate the cup-to-disk ratio. Optic disc and optic cup segmentation are typical small target segmentation problems in biomedical images. We propose to use an attention-based cascade network to effectively accelerate the convergence of small target segmentation during training and accurately reserve detailed contours of small targets. ResultsOur method, which was validated in the MICCAI REFUGE fundus image segmentation competition, achieves 93.31% dice score in optic disc segmentation and 88.04% dice score in optic cup segmentation. Moreover, we win a high CDR evaluation score, which is useful for glaucoma screening. ConclusionsThe proposed method successfully introduce anatomical knowledge into segmentation task, and achieve state-of-the-art performance in fundus image segmentation. It also can be used for both automatic segmentation and semiautomatic segmentation with human interaction.

Detection and diagnosis of pancreatic tumor using deep learning-based hierarchical convolutional neural network on the internet of medical things platform

Pancreatic cancer is one of the deadliest types of cancer and its prognosis is extremely poor in the present scenario. Automatic pancreatic tumor image segmentation is often provided by computer-aided screening (CAD), diagnosis and quantitative evaluations in radiology images such as CT and MRI. Tumor classification through these methods can also help to track, predict and endorse customized therapy as a part of effective treatment, without invasions of cancer. Nowadays, neural networks (NN) have shown promising results for precise pancreatic image segmentation. This paper presents a deep learning-based Hierarchical Convolutional Neural Network (HCNN) for pancreatic tumor detection. A recurrent neural network (RNN) is provided to meet the issue of spatial discrepancy segmentation across slices of adjacent images. The recurrent neural network generates CNN results and fine-tunes its segmentation by enhancing the smoothness and shape. Furthermore, the HCNN training and configurations objectives have been illustrated to the performance of pancreatic tumor image segmentation. The experimental results demonstrate that the proposed approach can improve the performance of the classifier and reduce the cost on the Internet of medical things platform (IoMT).