Pre Period Research Articles

Suicidal ideation and attempts among adolescents from a tertiary hospital in Turkey: A comparative study of pre and postpandemic periods.

This study aims to compare changes in rates of suicidal ideation (SI) and attempts (SA) among adolescents during pre, mid and later periods of the pandemic. This study included adolescents who presented to the adolescent medicine clinic in Turkey between March-May 2019 (prepandemic = T0), March-May 2021(mid period of the pandemic = T1) and March-May 2022 (late period year of the pandemic = T2). SI and SA data were assessed through the electronic hospital records of the "HEEADSSS" inventory. The charts of 2113 adolescents were evaluated. The rates of both SI (p = .015) and SA (p = .026) were determined to be higher during the pandemic (T1+T2) compared to the pre-pandemic period, with a 1.4-fold increase in SI and a 1.5-fold increase in SA. The rates of SI did not differ according to gender, (p = .090). In contrast, SA rate was significantly higher in females (7.3%) than males (3.6%) (p = .001). This study reveals an increase in SI and SA among adolescents during the first 2years of the pandemic. In challenging times, health professionals should prioritize the identification and treatment of mental health issues, including screening for depression and suicide risk.

Impact of the COVID-19 pandemic on surgical volume and outcomes in spine surgery: a multicentre retrospective study in Tokyo

ObjectivesTo investigate the effect of the COVID-19 pandemic on surgical volume and outcomes in spine surgery.DesignA retrospective cohort study using prospectively collected data.Setting and participantsA total of 9935 patients who...

Streamlining chemotherapy prior authorizations: Leveraging resources to cut delays and boost revenue.

573 Background: Prior authorizations (PAs) for systemic cancer treatments are a barrier to timely quality cancer care delivery. The high administrative burden to complete peer to peer’s (P2P) and appeals leads to care delays and revenue losses. At our tertiary academic cancer center, in partnership with our cancer registry and Epic teams, we shifted the clerical work required for PAs from clinicians to certified tumor registrars (CTRs) to increase authorization efficiency and decrease financial losses from denials. Methods: Clinicians place the treatment plan order which goes to the CTR work queue. We leveraged the Epic staging smart form to consolidate and auto-populate common elements needed for PA. The CTRs then complete and validate the form prior to the authorization specialists obtaining the PA. We compared the pre (1/2022-9/2022) and post-implementation (11/2022-5/2023) periods on our primary outcomes: average monthly number of PAs pending review (including P2P, appeals and authorizations requiring clarifying clinical documentation) and average time spent on PAs by the authorization specialists. We compared the same post implementation period to the same time the year before on the financial loss from denied PAs. Analyses were conducted using Welch's t-test. Results: There was an 11% reduction in the average monthly number of PAs pending review (350 vs 313; p=0.27) from pre to post implementation. There was an average improvement of 6 hours spent obtaining a final approval/per authorization (100 vs 106 hours; p=0.64) from pre to post implementation. In addition, there was a trend toward improvement in financial losses from PA denials from Dec 2022 to March 2023 and a cost savings of ~ 7 million dollars from the same time period pre-intervention; p=0.01 (Table). Conclusions: By leveraging the EHR and optimizing existing non-clinical staff workflows, we demonstrated a sustained decrease in the number of ambulatory PAs pending review, time spent on the PAs and significantly decreased financial losses from denials. Future work will include treatment and disease specific optimizations and evaluating the impact on clinician well-being.[Table: see text]

Outcomes of clinical pharmacist integration in a community oncology practice.

61 Background: There is a need to optimize the education and follow-up of patients receiving oral anticancer agents (OAAs) and high emetic risk chemotherapy (HEC) due to toxicities and implications of non-adherence and decreased dose intensity. The purpose of this study was to compare outcomes before and after the integration of a clinical pharmacist in a community oncology practice. Prior to the pharmacist, patients receiving OAAs and intravenous (IV) HEC received education and symptom monitoring by a team of nurses. Methods: This single center, retrospective analysis was conducted with data from February 2020 – December 2022. Up to 200 patients in the pre- and post-intervention periods each were identified. Charts were eligible for abstraction if patients were newly prescribed an OAA or IV HEC regimen during the study period. The post-intervention period began after the pharmacist’s start in March 2021. Patients receiving endocrine therapy for breast cancer were excluded. The following data were abstracted: patient demographics, OAA and IV HEC medication, line of therapy, cancer diagnosis, prescribed date, start date, education date, follow-up visits, emergency department (ED) and hospitalizations, reason for ED/hospitalization, IV HEC dose adjustments, delays and discontinuations. Chi-square analyses compared pre and post time periods. Results: Abstraction was completed for 179 patients in the pre-intervention (n=61 IV HEC; n=118 OAA) and 162 patients in the post-intervention group (n=44 IV HEC; n=118 OAA). After the pharmacist was integrated into the practice, more patients in the OAA group received education prior to their OAA start and had their medication adherence assessed. In the IV HEC group, more patients received guideline concordant care with a 4-drug regimen (including olanzapine) and were more often able to remain on their prescribed dose and dosing interval in the group with pharmacist care. Other outcomes remained approximately the same across time periods. Conclusions: Embedded clinical pharmacist care improved patient outcomes, including improved rates of patient education, medication adherence assessment, and improved dose intensity. [Table: see text]

Preanesthesia evaluation of oncological patients requiring palliative procedures

Palliative surgery in cancer patients are surgical procedures that do not aim to cure a patient but to improve their quality of life by providing relief from symptoms caused by an existing tumor. In addition to a patient´s higher risks, due to an increased number of related comorbidities, as well as the degenerative process caused by the pathology itself and its treatments, there are several other elements that may influence the decision-making process regarding the care to be provided. The needed solicitude for cancer patients with no prospect of cure should be of interest for both the patient and the health system in the management of welfare and epidemiological strategies. The objective of this review is to gather knowledge regarding the preparation of cancer patients requiring palliative surgical procedures in order to improve their quality of life, highlighting the important role of the anesthesiologist for optimizing the postoperative outcomes. In Brazil, performing an outpatient preanesthesia evaluation is recommended by the Federal Council of Medicine (CFM) under resolution number 2174/2017, since each preparation for an elective anesthetic procedure informs the anesthesiologist about the patient’s clinical conditions, as well as the possible risks that can be alleviated during the period prior to surgery and on planning special care in the pre, intra and postoperative periods, thus reducing the morbidity and mortality. These professionals are in a privileged position to alleviate suffering, as they have the necessary tools to deal with many symptoms that frequently occur in patients undergoing palliative care.

Measuring the Performance of Islamic Banking in Indonesia with Maqashid Sharia Index: Pre-Merger and Post-Merger Period

This study examines the performance of Islamic Commercial Banks in Indonesia in the pre and post-merger periods based on the combination of the Maqashid Syariah Index of Ibnu Ashur and Abu Zahrah. With three main indicators, namely tahdzib al fard (individual education), iqamah al adl ( justice), and maslahah (welfare). A comparative quantitative method using simple additive weighting (SAW) to measure the weight and performance rating of Islamic banking was used in this study. The results of the study indicated that the Islamic performance of Islamic Commercial Banks in Indonesia was below average. However, the merger has a positive impact on improving the performance of Islamic Commercial Banks in Indonesia in the post-merger period.
 Keywords: Islamic performance, Maqashid Sharia Index, merger

Impact on quality of life caused by vitamin D deficiency in bariatric patients: a literature review

Introduction: Bariatric surgery is a procedure performed to control obesity and its associated morbidities. Surgeries with malabsorptive and mixed techniques cause a deficit in the absorption of micronutrients, including vitamin D. Objective: The objective of this literature review was to investigate studies that verified the impact of vitamin D deficiency on the preand postoperative quality of life of individuals undergoing bariatric surgery. Methods: The search strategy was carried out in the virtual databases PubMed, Scielo, LILACS, Scopus, Web of Science, Embase, and the Virtual Health Library, in addition to gray literature such as Google Scholar, OpenGrey, Ibict/BDTD (Brazilian digital library of theses and dissertations) and ProQuest using the Medical Subject Headings (MeSH) and Health Sciences Descriptors (DeCS) descriptors with Boolean logical operators (AND, OR and NOT. The studies considered potentially eligible were those that presented in the same article the levels of vitamin D in the pre and postoperative period of the individuals, as well as the effect generated on their quality of life from where the data collection and analysis of the main outcomes found were made. Results: The online search resulted in 197 studies located in the virtual bibliographic databases and 115 in the gray literature. After removing the duplicates, 235 articles remained that were read by title and abstract, and 12 articles were chosen for reading the full text, leaving 7 that met the inclusion criteria. In most of the included studies, vitamin D deficiency was higher preoperatively than postoperatively in bariatric individuals. Better levels of 25(OH)D were correlated with reduced body weight, decreased BMI, and improved glycemic profile. Conclusion: Combating obesity remains an important issue in Public Health, with bariatric surgery being a safe way to reduce overweight since vitamin D levels are lower in the postoperative period of bariatric individuals, however, it is suggested to choose the appropriate technique to maintain ideal vitamin indices.

Natural opening of a new inlet in Chilika Lagoon: A cause and impact analysis

Natural opening of inlet(s) is very common along the shorefront of Chilika Lagoon. Inlet openings in most of the cases have been triggered due to the narrow spit width and cyclonic storm/ depression (CS/D). Wave height and energy get further enhanced when the CS/D occurs concurrently with a full moon/ new moon with a lag/lead of 2–3 days. This has happened many times in the past. Recently, a new inlet was opened on 13th July 2022 due to deep depression (DD) over the northwestern Bay of Bengal from 09th to 12th July 2022. A cyclonic circulation prevailed over the northwest and adjoining west-central Bay of Bengal off the south Odisha-north Andhra Pradesh coast in lower and mid-tropospheric levels tilting southwestwards with height. Wave heights during the pre and post-inlet opening period spanning over one month suggest the peak wave condition coinciding with the period of the inlet opening. Geomorphological conditions of the spit before and after the inlet opening were monitored. Results indicate fast expansion of inlet width due to erosion of the spit on both sides of the inlet and the tidal incursion into the lagoon predominantly during the full-moon day/new moon day. After the opening of a narrow inlet of width 246 m on 13 July 2022, it was doubled within a month. Shoreline analysis using Sentinel 2A imagery for pre- and post-inlet opening was carried out and validated with observations. Oceanographic conditions near the new inlet were simulated and monitored by deploying a Seaguard RCM current meter with a pressure and temperature sensor. This study assessed the reasons for the inlet opening and monitored the geomorphological changes after the inlet opening. More importantly, the impact of the new inlet on lagoon ecosystem was assessed, which has severe implications for the management of the lagoon ecosystem.

The Impact of Working Capital Ratios on Operational Performance under Covid-19 Pandemic: Evidence from Listed Material Sector Firms in Sri Lanka

This paper investigates whether the Covid-19 pandemic impacts the association between working capital ratios and operational performance. Using comparison tests by taking a sample of listed material sector firms in Sri Lanka from 2019Q1 to 2021Q2, this study first examines whether working capital ratios have become statistically different between pre Covid-19 period and during the Covid-19 period. Secondly, this paper employs panel regression analysis for pre-Covid-19, during Covid-19 and the full samples to identify how Covid-19 has reshaped the association between working capital ratios and operational performance measured by return-on-sales (ROS). The results show that, apart from days-sales-outstanding (DSO), other working capital measures are similar between the pre-Covid-19 period and during the Covid-19 period. Further, the results suggest that ROS is higher when firms delay payments to suppliers during pre Covid-19 period. However, this paper finds that ROS is not responsive to working capital ratios during the Covid-19 period.

A comparative study of air quality between pre and post COVID-19 periods in India

A comparative study of air quality between pre and post COVID-19 periods in India

Essential oil blend supplementation in the milk replacer of dairy calves: Performance and health.

Supplementation of dairy calves with essential oils in the liquid diet can reduce the incidence and severity of infectious diseases and promote better performance. Our objective was to evaluate an essential oil blend containing peppermint, eucalyptus, and menthol crystals and its effect on performance and health during the pre and postweaning period of dairy calves. At birth, 40 dairy calves (34 males and 6 females) were blocked according to sex and birth weight, randomly assigned to one of two treatments-commercial milk replacer diluted at 14% (MR) and the same liquid diet plus essential oil blend (MREO) at a dose of 4 mL per calf per day, divided into two meals during the first 28 days of life. Calves were individually housed and fed 6 L/d of the liquid diet, divided into two meals, and received starter concentrate and water ad libitum. Weaning was gradually reduced by 1L per day at d 51 until complete weaning at 56 days. After weaning, calves were evaluated until 70 days of age, when the experimental period ended. Intake, fecal, and health scores were evaluated daily, weight and body measures were recorded weekly, and blood parameters were evaluated at weeks 1, 2, 3, 4, and 8. Calves fed MREO tended to have higher total dry matter intake during the preweaning period. Furthermore, MREO calves had lower health scores and fewer days with a health score ≥ 4 (suggestive of bronchopneumonia), tended to lower coughing days and fewer veterinary interventions preweaning, and tended to lower health scores postweaning. The supplementation with a blend of essential oils containing peppermint, eucalyptus, and menthol crystals can reduce respiratory problems. Further studies are needed to investigate the dose and the supplementation period.

Diversity of Non-Influenza Respiratory Viruses Associated with Influenza-Like Illness during 2009 pre and pandemic periods in Sao Paulo, Brazil, a Historical Overview

Background and objective: During the 2009 influenza A (H1N1) pandemic, 60% of the respiratory specimens collected from patients under surveillance for influenza-like illness (ILI) in São Paulo, Brazil, tested negative for influenza A and B by Real-Time RT-PCR (RT-qPCR) assays. In this retrospective study, we identified the diversity of other respiratory viruses associated with ILI during the pandemic period and added the benefit of RT-qPCR for their detection. Methods: Five-hundred and forty-two influenza RT-qPCR negative respiratory specimens from ILI patients collected from Jan - Dec 2009, that also tested negative by a commercial Indirect Immuno Fluorescence (IIF) assay for the Respiratory Syncytial Virus (RSV), Parainfluenza (PIV) PIV1, PIV2, PIV 3 and Adenovirus (AdV) were retested by a panel of RT-qPCR assays for the other respiratory viruses, including RSV, Human Metapneumovirus (HMPV), PIV 1-4, AdV, Human Coronaviruses (HCoV) OC43, 229E, NL63 and HKU1, Rhinovirus (RV), Enterovirus (EV) and Human Bocavirus (HBoV). Results: Of the 542 negative specimens, 428 (78%) were positive by RT-qPCR for another respiratory virus: In descending order: RV (149, 27%); RSV (41, 8%); AdV (32, 6%); HMPV (29, 5%); PIV3 (19, 4%); PIV1 (3, 1%); HCoV-OC43 (9, 2%); HBoV (9, 2%); PIV4 (6, 1%); HCoV-HKU1 (6, 1%); EV (5, 1%); HCoV-229E 4 (4, 1%); HCoV-NL63 (3, 1%). Co-detections of two viruses (98, 18%) and three viruses (12, 2%) were common. Conclusion: This retrospective study revealed a high prevalence of respiratory viruses other than influenza associated with ILI during the pandemic period and highlights the superiority of RT-qPCR over IIF for ILI surveillance.

Comparing Online and Face-to-Face Performance in Scientific Courses: A Retrospective Comparative Gender Study of Year-1 Students.

As a result of COVID-19 pandemic, medical education at the Arabian Gulf University was instructed to apply online teaching instead of face-to-face for all phases of teaching at the University. Phase-1 is concerned with basic science courses delivered to year 1 students. We conducted this study to detect if there are any differences in the performance of medical students between online and face-to-face ways of learning. Also, a comparison between male and female performance in scientific courses was carried out in pre and during COVID-19 periods. The participant were first year students for pre COVID-19 period from 2018 to 2019 and during COVID-19 period from 2020 to 2021. The university used Moodle and Zoom as an online way of teaching. The students' performance in the year 1 (three-semester) -online period of teaching were compared with a three-semester-performance of conventional teaching prior to COVID-19. This is a retrospective study that attempts to shed some light on the efficiency of AGU experience in online learning for year 1 (Phase I) students. This study evaluates the outcome of both, online and face-to-face examinations for scientific courses. The results showed that the mean performance of year one medical students in all basic scientific courses (Phase I) during the coronavirus pandemic was greater than the mean performance before the pandemic with the exception of the Biostatistics course. The results by gender showed that the mean performance of females was better than males across all scientific courses before coronavirus. Also, during the COVID pandemic, the mean performance of females was better than males in all basic science courses. Year -1 students' performance in science courses during the coronavirus period seems better than pre COVID19 era. Females' performance was better than males' in both periods; pre and during COVID -19 periods.

The Evaluation of Serum Endocan, Interleukin-6, and CRP Levels Following Sleeve Gastrectomy.

The excessive accumulation of fat tissue in obesity is the source of chronic low-level inflammation and causes future dysmetabolic and cardiovascular disorders. Removal of this excessive fat tissue with the aid of bariatric surgery (BS) techniques, such as sleeve gastrectomy, may reverse adverse inflammatory outcomes. The aim of this study is to investigate the impact of sleeve gastrectomy on inflammatory markers, specifically endocan, IL-6, and CRP, in individuals with obesity. Thirty-two patients with class 3 obesity and class 2 obesity + comorbidities were enrolled in the study. Clinical characteristics including age, comorbidity, body mass index (BMI), waist, and hip circumferences of the participants were noted before and 3 months after sleeve gastrectomy. Blood samples were collected during those periods to assess biochemical features such as serum endocan, interleukin-6 (IL-6), C-reactive peptide, fasting insulin, glycosylated hemoglobin A1c levels, and lipid panel. A statistical package program was used for the analysis of those parameters, and p<0.05 was accepted as significant at a 95.0% confidence interval. BMI reduced from 43.55±6.78 to 36.16±6.14 kg/m2 within 3 months following BS (p<0.001). Preoperative serum endocan, IL-6, and CRP levels were correlated with BMI, and in line with BMI reduction, their serum levels decreased after BS (p<0.05). HOMA-IR also reduced after BS, and both in the pre and post-BS periods correlated with BMI, IL-6, endocan, and CRP levels (p<0.05). The mean total body weight loss was 20.4% within 3 months post-BS. BS techniques are effective in weight loss and reversing the inflammatory processes caused by obesity. Serum endocan, IL-6, and CRP levels are promising markers for describing obesity-related inflammation and objectively checking the alleviation of inflammation following BS.

UNVEILING THE UNTOLD STORIES: DOCUMENTARY FILMS TACKLING LABOUR ISSUES IN INDIA

Since time immemorial, film is a strong and powerful medium through which emotions and feelings can be conveyed. A documentary film is something very important as it portrays the reality and there is nothing fictional and one such reality of the Indian society is the labour plight. Complications that the labourers in India face is nothing new but there is hardly any medium that sheds light on their problems and most of the population is not concerned about them. Labour plight in India is like a chronic disease that is never ending. In such a situation, researchers have done an analysis on documentaries concerning labour issues from pre COVID and COVID period. The issue of child labour in the society is also analysed. The documentary has four parts. The introduction explains what a documentary is and its origin. Details about the past labour issues along with figures are included in the review of the literature. The analysis portion describes the documentaries that were taken for analysis and the detailed analysis of each film taken is included. The analysis is conducted on 5 pre COVID era documentaries, 2 of which includes the issue of child labour and 3 post COVID era documentaries. The conclusion is the last and final part. The goal of the conclusion is to promote the concerns of the labourers and to encourage the use of ethics and ensure values and safety while filming the true lives of the proletariat that easily gets affected by the elite class.

Hematopoietik Kök Hücre Nakli Türüne ve Nakil Öncesi Mevcut Polifarmasiye Bağlı Olarak İlaç-İlaç Etkileşimi Farklılıkları

Introduction: Drug drug interactions can effect the success of stem cell transplantation process. Therefore, analyzing the risk of these interactions would be helpful for practitioners. This study was conducted to identify drug-drug interactions in allogeneic and autologous stem cell transplantation patients before and after transplantation. &#x0D; Methods: Patients who underwent allogeneic stem cell transplantation and autologous stem cell transplantation were included in the study. Patients’ treatment sheets were collected ten days before transplantation day, on the transplantation day, and ten days after transplantation day. Drug-drug interactions were analyzed by using four drug-drug interaction checking databases.&#x0D; Results: 50 patients from both transplantation types were included. The mean ages for allogeneic and autologous transplants were 42.4 and 51.8, respectively. 52% of allogeneic transplants and 28% of autologous transplants were on ≥5 drugs at tenth day before transplantation. The means of interactions in allogeneic and autologous stem cell transplantation patients were 75.42 and 43.62, respectively. The detection of at least one contraindicated interaction in allogeneic and autologous transplant patients were 94% and 92%, respectively. In 48% of allogeneic transplants and 36% of autologous transplants, two or more contraindicated interactions were detected.&#x0D; Conclusion: Allogeneic stem cell transplantation patients experienced almost two times more drug-drug interactions than autologous stem cell transplantation patients. Transplantation type, being in the pre and post-transplantation period and the drug number at the beginning of the transplantation process matter in terms of the number of drug-drug interactions. Identifying interactions in terms of transplantation type and existing medications is very important.

Differences in carbon risk spillovers with green versus traditional assets: Evidence from a full distributional analysis

This paper studies the dynamic risk spillover of carbon and financial markets through a quantile-based framework. Potential asymmetry of the cross-market spillover is examined from the perspectives of the data distribution, differences in financial asset types, and pre and post periods of the COVID-19 pandemic onset. Using an international daily dataset covering the recent decade, our empirical analysis offers supportive evidence of established theoretical expectations. The empirical results demonstrate a unidirectional risk spillover from the carbon market to both traditional and green asset markets. The spillover is weakly positive under various market conditions, indicating a consistent diversification gain of carbon commodities against financial assets. Carbon's sheltering role is further enhanced as a hedge for green assets, in particular conditions when the risk levels of carbon and green markets are high and low, respectively. In addition, the onset of the pandemic is found to strengthen cross-market risk spillovers.

Interdisciplinary experiences between speech therapy and dentistry in the pre and postoperative period for bariatric surgery

The aim of this study was to report the experiences of interdisciplinary care between speech therapy and dentistry, for adult patient’s pre and postoperatively of gastroplasty, in Reference Service for Bariatric Surgery at the Clinics Hospital at the Federal University of Pernambuco, in the city of Recife, northeastern Brazil. This service has a multiprofessional team of health and social assistance professionals, who monitor individuals with obesity and associated comorbidities, mainly Diabetes and Systemic Arterial Hypertension (SAH), with a view to a comprehensive and humanized treatment, aiming at a better quality of life for this target population. After the beginning of the monitoring by Speech Therapy, there was the request for the opinion and intervention of Dentistry, particularly in the context of the performance of the masticatory function. As of the year 2022, 27 adult patients, aged between 18 and 59 years old received the evaluation, orientations and interventions together, particularly regarding orofacial motricity and oral rehabilitation. In this context, the biggest challenges are related to periodontal disease, with tooth mobility and the loss of many teeth due to caries lesions and to tooth fractures due to clenching and generalized sensitivity

Going public and innovation: Evidence from the ChiNext stock market

Innovation can drive corporate value and enhance competitiveness. Due to the high risks, long-term nature, and exclusivity of innovative projects, it is difficult for companies to meet R&D (Research & Development) investment needs through internal funding. An IPO (Initial Public Offering) represents the first major liquidity event in a firm’s lifecycle since founders and initial investors realize value from the sale of their equity stakes and consequent diversification of ownership. Firms raise funds from investors in the capital market through initial public offerings (IPOs), which serve as an essential means of corporate financing. Based on this, this paper investigates the effects of going public on innovation using the Difference-in-Differences approach. The treatment group comprises public firms on the ChiNext stock market between 2010 and 2016. As a control group, non-listed firms submitted IPO applications to the China Securities Regulatory Commission (CSRC) but failed during the same period. Consequently, the final data is collected from 2007 to 2019, encompassing the three years pre and post-IPO periods. We find going public can prompt corporate innovation, and this positive effect is achieved through three channels: alleviating financing constraints, accumulating human capital, and mitigating agency problems. Heterogeneity analysis reveals that the positive relation is more pronounced in non-high-tech firms, higher competitive industries, weaker intellectual property protection firms and the growth-stage firms. Taking into account the characteristics of IPO, we find that the promotion of corporate innovation is more pronounced in samples with pre-IPO venture capital or private equity investments and lower levels of underpricing during IPO. Additionally, the increased innovation induced by IPO positively impacts long-term value and total factor productivity. The analysis reveals a complex trade-off between public and private ownership. It enriches the research on the impact of IPO behavior on innovation and provides new empirical evidence to improve the multi-level capital market.

Does the merger improve the operating performance of the company? Evidence from the beverage industry in India.

Background: There is fierce market competition both locally and globally. Every organisation seeks to maintain itself and, more crucially, to develop quickly through inorganic means. The expansion of a company through mergers and acquisitions is an inorganic process. Organic growth takes a very long period and is time-bound, but inorganic growth through mergers may be achieved quickly. This research aimed to determine whether the operating results of Indian beverage firms have improved after the merger or not. Methods: In order to assess merger-related advantages to the acquiring firms, this study used the operating performance technique, which contrasts the pre-merger and post-merger performance of corporations using accounting data. Secondary data were used to carry out this study. The operating performance was assessed on six operating parameters (ratios) i.e. Operating Profit Margin, Gross and Net Profit Margin, Debt-Equity, Return on Net Worth and Capital Employed. The comparison was done for three years pre and post-merger period of these operating ratios. Results: The findings demonstrate that mergers do not seek to increase owner wealth. This finding shows that rather than just becoming larger and achieving covert goals, managers should pay more attention to post-merger integration challenges in order to produce merger-induced synergies. Conclusion: This study shows that the M&As have not had a good effect on a company's operating performance, especially for the chosen beverage companies in India. Since financial measures cannot fully account for the influence of mergers on business performance, future research may create other metrics for merger-related gains. Research that provides profound insights into the causes and trends of post-merger business performance through the different types of mergers and industries would also be beneficial.