Preoperative Bacteriuria Research Articles

Bacteraemia during prostatectomy and other transurethral operations: influence of timing of antibiotic administration.

The relation between the timing of prophylactic antibiotic administration and the occurrence of bacteraemia during transurethral operations was studied in 112 patients whose urine was infected before operation. Blood cultures taken during operation were positive in 15 (60%) of 25 patients who did not receive appropriate antibiotics, in 13 (21%) of 63 patients who were given appropriate antibiotics less than 24 h before operation, and in none of 24 patients in whom antibiotic "cover" was started more than 24 h before operation. In all cases the bacteraemia was transient. No patient developed septicaemia. The implications of these findings for the optimum timing of antibiotic administration to patients with preoperative bacteriuria are discussed.

Bacteriuria in patients undergoing prostatectomy.

A review of the literature revealed that the reported incidence of bacteriuria arising before and after prostatectomy varied considerably, that there had been little investigation of the organisms isolated, and that the value of chemoprophylaxis at the time of prostatectomy was unproven. Using standard criteria and technical procedures, 248 patients undergoing prostatectomy were studied over a two-and-a-half-year period. Preoperative bacteriuria occurred in 28% of patients. The incidence was significantly increased in patients catheterised before operation (44%) compared with those who had not been catheterised (18%). The incidence of bacteriuria was directly related to the duration of catheter drainage. Postoperatively, 40% of patients with sterile urine at the time of prostatectomy developed bacteriuria. There was an increased prevalence of Enterococcus and coagulase-negative Staphylococcus isolates from postprostatectomy bacteriuria compared with preprostatectomy bacteriuria. Based on this information, suggestions can be made regarding the choice of a suitable chemoprophylactic agent and the optimum timing and duration of its administration.

Urinary tract infection following prostatic surgery (author's transl)

A comparative study was conducted on the severity and course of postoperative urinary infections in prostatic adenoma patients with preoperative bacteriuria and patients without infection. In both groups urinary infections showed a similar tendency to resolve, whereas a significant increase of polyresistant bacterial strains was noted in patients with preoperative bacteriuria. A comparison of 100 patients who had undergone transurethral resection and 100 patients who had undergone prostatectomy showed that severity and course of the postoperative urinary tract infection did not differ.

Persistent bacteriuria following simple suprapubic prostatectomy.

Among 65 patients who underwent simple suprapubic prostatectomy, three consecutive quantitative estimations of clean voided midstream urine were carried out, i.e. before operation, on discharge from hostpital and six months or later after operations (late review), respectively, and some factors that will affect persistent significant bacteriuria were discussed. The results thus obtained were as follows. 1. Incidence of persistent significant bacteriuria at late review was 30.8% in patients with significant bacteriuria preoperatively and this figure was higher than 17.7% in patients without significant bacteriuria preoperatively. 2. Duration of postoperative indwelling urethral catheterization plays a less significant role than the presence of preoperative bacteriuria in the persistent significant bacteriuria on discharge and at late review. 3. Size of the enucleated prostate also showed no significant relationship to the persistent significant bacteriuria at late review.