Introduction. In normal controls, female gender and low-normal haematocrit levels have pro-coagulant effects. We utilized Thromboelastography® (TEG) to assess, I) effects of gender on coagulation, and II) relationship with standard coagulation tests (SCT). In contrast to SCT, TEG® measures clot formation, strength, and lysis in whole blood under low shear forces resembling physiologic venous flow. TEG parameters usually measured are R time, K time, Angle, and MA or Maximum Amplitude. ”Shorter R and K time, and larger Angle and MA are indicative of accelerated coagulation”. [Reference values for R 2-8 min, K 1-3 min, Angle 55-78°, MA 51-69 mm]. Method. Retrospectively, records of 146 adult CABG surgery patients were reviewed. Baseline preoperative kaolin heparinase TEG® parameters R, K, Angle, and MA were recorded. Adults with pre-existing coagulation abnormalities, liver failure, or renal failure were excluded. Results. Preoperatively, there was no gender differences in SCT i.e. [platelet count (P 0.39), PT (P 0.32), PTT (P 0.35)] and baseline creatinine (P 0.15). But females were older (P 0.001), had lower BSA (P 0.0001) and lower preoperative haematocrit (P 0.0001). Females demonstrated accelerated coagulation status compared to men, shorter R [7.67 1.77 vs. 6.65 1.69 min (P 0.003)], shorter K [1.94 0.59 vs. 1.59 0.45 min (P 0.002)], larger Angle [63.61 6.33 vs. 67.74 5.90 ° (P 0.001) and larger MA [63.13 6.33 vs. 67.74 67.63 mm (P 0.0002). Gender specific TEG® data was further analysed by percentiles into 4 sub-groups [ P25, P25-P50, P50-75, and P75]. Compared to males, fewer females had R values 75 (86.87% vs. 61.11%) [P 0.0067], more females had K values P25 (22.77% vs. 50.0%) [P 0.0038], Angle values P75 (5.88% vs. 22.22%) [P 0.0138], and MA values P75 (52.94% vs. 86.11%) [P 0.0045]. Relationship of individual TEG parameters with SCT: a) TEG R, directly to pre-op PTT (P 0.04)] and no relation with pre-op PT, platelet count and haematocrit (P 0.05). b) TEG K, inversely to pre-op platelet count (P 0.03)], directly to haematocrit (P 0.0001) and no relation with pre-op PT and PTT (P 0.05). c) TEG Angle, inversely to pre-op haematocrit (P 0.0001)], no relation with Pre-op PT, PTT, and platelet count (P 0.05). d) TEG MA, directly to pre-op platelet count (P 0.003), inversely to pre-op haematocrit (P 0.0001) and no relation with PT and PTT (P 0.05). Conclusions. Despite no gender differences in baseline SCT in adult CABG surgery patients, TEG® demonstrated female gender and low-normal haematocrit were associated with accelerated coagulation.