Intelligent reflecting surfaces (IRSs) are a key enabler of various new applications in 6G smart radio environments. This article aims to enhance self-interference (SI) cancellation for breath tracking with commodity WiFi devices by utilizing an IRS prototype system. SI suppression is a crucial requirement for breath tracking with a single antenna site, as the SI severely limits the radio sensing range by shadowing the received signal with its own transmit signal. To this end, we propose to assist SI cancellation by exploiting an IRS to form a suitable cancellation signal in the analog domain. Building upon a 256-element IRS prototype, we present results of breath tracking with IRS-assisted SI cancellation from a practical testbed. We use inexpensive WiFi hardware to extract the channel state information (CSI) in the 5-GHz band and analyze the phase change between a colocated transmitter and receiver with added local oscillator (LO) synchronization. As a result, we can track the breath of a test subject regardless of position in an indoor environment with a room-level range. The presented case study achieves promising performance in capturing the breath frequency and breathing patterns.