Photoplethysmography (PPG) signal comprises physiological information related to cardiorespiratory health. However, these signals are often contaminated by motion artifacts, resulting in low-quality noise-enriched signals. Therefore, it is crucial to ensure high-quality signals to extract accurate cardiorespiratory information. Although several rule-based and Machine-Learning (ML) - based approaches exist for PPG signal quality estimation but their effectiveness is questionable during evaluation in diverse datasets. This study proposes a lightweight, slim CNN architecture that utilizes a novel Quantum Pattern Recognition (QPR) technique for signal quality assessment. The proposed algorithm is initially validated on the University of Queensland database (clinical) and a noisy PPG database (non-clinical) collected from the ‘Welltory app’. A total of 28366, 5 s signal segments are preprocessed and transformed into image files of 20 × 500 pixels. The image files and heart rate obtained from the PPG signals are treated as input to the 2D slim CNN architecture. The developed model classifies the PPG signal as ‘good’ or ‘bad’ with an accuracy of 98.5%, 99.2% sensitivity, 97.5% specificity, and 99% F1-score. The classified database is further used for cuffless Blood Pressure estimation, and estimation error is reduced ≥ 1 mmHg w.r.t. reference BP signals. Finally, the proposed scheme is validated in STM32 series board for a resource-constrained wearable implementation. The computational load of the algorithm is reduced by network pruning and quantization for edge-device implementation, and it achieves an accuracy of 94.3%. This extensive analysis concludes that a slim architecture, along with a novel spatio–temporal pattern recognition technique, improves the system’s performance.