As China continues to strengthen the cultivation of specialized and ultra-new small and micro enterprises, and promote the development of related enterprises in China's basic industries, now "specialization and innovation" enterprises have become a new power to enhance the industrial chain power and high-quality development pattern. However, the development of all kinds of "little giant" enterprises is still in the middle and low end of the industrial chain, the core creativity is still very lacking, and it is easy to be eliminated and replaced in the fierce competition of existing technology and innovation. In this regard, from the perspective of "innovation", this paper will use Probit model to empirically analyze the internal and external factors and constraints that affect the innovation behavior of small and medium-sized enterprises, among which government subsidies and human capital cultivation have significant negative and positive effects on enterprise innovation respectively. At the end of the paper, we try to find a way to solve the core problem of "innovation difficulty" of small, medium and micro enterprises under the background of "specialization and innovation" from multiple perspectives.
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