Purpose3D-printed patient-specific instruments (PSIs), such as surgical guides and implants, show great promise for accurate navigation in surgical correction of post-traumatic deformities of the distal radius. However, existing costs of computer-aided design and manufacturing process prevent everyday surgical use. In this paper, we propose an innovative semiautomatic methodology to streamline the PSIs design.MethodsThe new method was implemented as an extension of our existing 3D planning software. It facilitates the design of a regular and smooth implant and a companion guide starting from a user-selected surface on the affected bone. We evaluated the software by designing PSIs starting from preoperative virtual 3D plans of five patients previously treated at our institute for corrective osteotomy. We repeated the design for the same cases also with commercially available software, with and without dedicated customization. We measured design time and tracked user activity during the design process of implants, guides and subsequent modifications.ResultsAll the designed shapes were considered valid. Median design times ( tilde{t} ) were reduced for implants (( tilde{t}_{I} ) = 2.2 min) and guides (( tilde{t}_{G} ) = 1.0 min) compared to the standard (( tilde{t}_{I} ) = 13 min and ( tilde{t}_{G} ) = 8 min) and the partially customized (( tilde{t}_{I} ) = 6.5 min and ( tilde{t}_{G} ) = 6.0 min) commercially available alternatives. Mouse and keyboard activities were reduced (median count of strokes and clicks during implant design (( tilde{s}_{I} ) = 53, and guide design (( tilde{s}_{G} ) = 27) compared to using standard software (( tilde{s}_{I} ) = 559 and ( tilde{s}_{G} ) = 380) and customized commercial software (( tilde{s}_{I} ) = 217 and ( tilde{s}_{G} ) = 180).ConclusionOur software solution efficiently streamlines the design of PSIs for distal radius malunion. It represents a first step in making 3D-printed PSIs technology more accessible.