ObjectiveStroke can result in significant mental and physical impairment. Training healthcare professionals on effective strategies for mitigating stroke-related quality-of-life issues is crucial in facilitating comprehensive stroke management. This study aims to evaluate the impact of an interprofessional education (IPE) experience on students’ attitudes regarding post-stroke disability. MethodsIn this pre-post interventional study, pharmacy and medical students received an electronic patient chart and a store-and-forward video depicting physical and cognitive impairment in a stroke patient. Students were instructed to discuss the acute management and post-discharge needs of the patient from an advocacy perspective. After the IPE experience, students completed the student perceptions of interprofessional clinical education-revised instrument (SPICE-R2) and an unvalidated disability attitudes survey. The surveys were analyzed using a paired t-test. Additionally, students reflected on the prompt, "What are some things you had NOT considered prior to this IPE?”. ResultsSeven hundred and eight students completed the surveys. Post-IPE, there was a significant improvement in all domains of the SPICE-R2. On the disability survey, there was significant improvement on all statements, including rate your comfort with; 1.) discussing the expected disabilities associated with new-onset stroke and 2.) discussing strategies for improving the quality of life of a patient who has long term disabilities. On the self-reflections, 31.7% (N=211) had not considered the need for post-stroke care services prior to this IPE. ConclusionThis IPE experience was instrumental in improving student perspectives regarding post-stroke disability.