BackgroundShisha smoking is a common practice among the population in Arabic countries.Shisha smoking has a negative effect on lung function; it is probably one of the causes for chronic obstructive pulmonary disease (COPD).ObjectiveDetection of COPD among Shisha Smokers in the Fayoum Governorate.DesignProspective study.SettingFayoum University Hospital in Egypt between 2016 and 2017.Patients and methodsOf the 300 participants, 200 were shisha smokers for more than 20 years or their age above 40 years and 100 of them were nonsmoker volunteers. History of smoking was taken from the patients with recording of the COPD assessment score and then general and local examination was done followed by flow volume loop and finally by a chest radiography (posteroanterior view).Statistical analysis: case–control studyCoding of the data was done and then entered with SPSS (statistical package for the social sciences) version number 24. After that data was summarized using mean, SD, median, minimum and maximum in the quantitative data with using frequency (count) and relative frequency (percentage) for categorization of data.ResultsOut of the 300 male patients included in this study 51% has obstructive airway disease and 19% had restrictive airway disease.The mean age was 56.20±10.98 years. Number of hagars smoked by the COPD patients were 10.82±9.88 hagars per day with a duration of smoking of 24.87±12.36 years.ConclusionShisha smoking increases the risk of COPD and this risk increases with the increase in the duration of smoking and number of hagar smoked was the conclusion of the study.