A 65-year-old patient, melanoderma, smoker since 10 years old, came to the oral and maxillofacial service complaining of pain in the jaw on the right side for one year. The intraoral physical examination revealed an ulcerated, leukoplasic and erythematous lesion in the region of the right posterior alveolar ridge. Imaging exams showed a radiolucent, unilocular lesion, with a well-circumscribed, radiopaque halo in the posterior mandibular region on the right side. Hematological examination was requested and an incisional biopsy was performed. The histopathology revealed a fragment of malignant neoplasm of epithelial origin characterized by the proliferation of tumor cells arranged in islands growing inside the connective tissue and a fragment of a cystic lesion of odontogenic origin characterized by the presence of a pathological cavity lined by stratified epithelium, with a consistent diagnosis of primary intraosseous carcinoma. The patient was referred to the oncology service. A 65-year-old patient, melanoderma, smoker since 10 years old, came to the oral and maxillofacial service complaining of pain in the jaw on the right side for one year. The intraoral physical examination revealed an ulcerated, leukoplasic and erythematous lesion in the region of the right posterior alveolar ridge. Imaging exams showed a radiolucent, unilocular lesion, with a well-circumscribed, radiopaque halo in the posterior mandibular region on the right side. Hematological examination was requested and an incisional biopsy was performed. The histopathology revealed a fragment of malignant neoplasm of epithelial origin characterized by the proliferation of tumor cells arranged in islands growing inside the connective tissue and a fragment of a cystic lesion of odontogenic origin characterized by the presence of a pathological cavity lined by stratified epithelium, with a consistent diagnosis of primary intraosseous carcinoma. The patient was referred to the oncology service.
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