Post-stroke Patients Research Articles

Организационные аспекты домашней телереабилитации пациентов, перенесших инсульт.

Restoring neurological functions after a stroke is one of the main medical and social problems of the 21st century. Telemedicine technologies increase the accessibility and coverage of medical care for patients living remotely from medical organizations, with limited mobility, and also during periods of pandemics. However, to date there are no methodological recommendations for making management decisions on organizing home telerehabilitation for patients who have suffered a stroke. This is due to the comparative novelty of technologies and insufficient knowledge of clinical studies, absence or lack of managerial experience. Therefore, the purpose of this article – develop a methodological framework for drawing up methodological recommendations when making management decisions on organizing home telerehabilitation after a stroke, which is a relevant area in the context of the digital transformation of healthcare. Materials and methods. The study was conducted using analytical methods and information retrieval. Results. Matrices have been developed to assess the readiness of the patient and the medical organization to conduct personalized telerehabilitation. A management decision-making scheme is proposed to assess the possibility of organizing telemedicine rehabilitation of a post-stroke patient at home. Findings. The results of the study may be useful to healthcare organizers and become the basis for the development of methodological recommendations when making management decisions on organizing home telerehabilitation for patients of the relevant profile.

Functional MRI evaluation of hyperbaric oxygen therapy’s effect on hand motor recovery in a chronic post-stroke patient: a case report and physiological discussion

The objective of the case report was to evaluate a specific HBOT protocol as an effective treatment for stroke rehabilitation, specifically improving hand motor function in chronic post-stroke patients. Stroke is the second leading cause of long-term disability worldwide. About 80% of individuals with acute stroke present upper-limb motor impairment, and 50–60% will have persistent disability or weakness at the chronic phase. Impaired upper-limb motor function is highly associated with low self-care ability, limited mobility and poor quality of life. In recent years, there has been evidence of the neuroplasticity effects of HBOT, and HBOT was found to induce neuroplasticity in chronic stages, even years after brain injury. While the healthcare system is primarily focused on teaching patients to live with their impairments, this case report evaluates the effect of a specific hyperbaric oxygen therapy (HBOT) protocol on true stroke rehabilitation, specifically, improving upper-limb function. This case report studied motor task functional MRI (fMRI) activation and resting-state functional connectivity (rsFC) in a 61-year-old right-handed male patient who suffered hemiparesis and physical weakness in the right upper limb two years after his acute insult, pre- and post-treatment of 60 daily HBOT sessions. Motor functions were assessed at baseline and after the treatment using the Fugl–Meyer assessment (FMA) and the handgrip maximum voluntary contraction (MVC). Following the HBOT protocol, the patient’s FMA score improved from 17 (severe impairment) to 31 (moderate impairment), and there was an increase in fMRI activation in both the supplementary motor cortex (SMA) and the premotor cortex (PMA) bilaterally during trials involving the right hand. The lateralization index (LI) decreased from 1 to 0.63, demonstrating the recruitment of the contralesional hemisphere. The region of interest, ROI-to-ROI, analysis revealed increased post-intervention inter-hemispheric connectivity (P = 0.002) and a between-network connectivity increase (z-score: 0.35 ± 0.21 to 0.41 ± 0.21, P < 0.0001). Seed-to-voxel-based rsFC analysis using the right SMA as seed showed increased connectivity to the left posterior parietal cortex, the left primary somatosensory cortex and the premotor cortex. This case report provides additional insights into HBOT-induced brain plasticity and functional improvement in chronic post-stroke patients, and shows HBOT’s potential as an effective, valuable treatment option for those suffering with lingering symptoms after a stroke. This work was conducted by a research team at the Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center and Tel Aviv University, and published in Frontiers in Neurology. This is the full abstract presented at the American Physiology Summit 2024 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.

Neuraxial Block in A Post-Hemorrhagic Stroke Pregnant Patient

The selection of anesthetic methods for labor and delivery in individuals with elevated intracranial pressure relies on careful consideration of the risks and benefits. While neuraxial analgesia and anesthesia are favored for healthy individuals, they might not be suitable for individuals with intracranial lesions or a heightened risk of bleeding. Neuraxial block in post-stroke patients raises a concerning question about its safety due to the risk of herniation. The risk of perioperative major vascular events and mortality between general anesthesia and regional anesthesia in post-stroke patients is comparable. However, the neuraxial block shows benefits regarding airway manipulation and lower risk of thromboembolism. A successful and safe neuraxial anesthesia in a pregnant patient with a history of hemorrhagic stroke was presented in this case report.

Health Education Concerning Stroke Patients Treatment on Family's Readiness to Go Home for Non-Hemorragic Stroke Patients

Stroke has physical and mental impacts so that stroke clients depend on their families and need long-term care and recovery. Therefore, family readiness is needed in caring for stroke patients. Through health education using leaflets, we try to help patient family members be ready to care for stroke patients while at home. The research aims to determine the effect of health education on the readiness to return home to families of non-hemorrhagic stroke patients in the Inpatient Room at RSU PKU Muhammadiyah Delanggu. The research used a pre-experimental design method type one group pretest-posttest. The sample was taken by purposive sampling and obtained 32 respondents using the Slovin formula. The instrument uses leaflets and questionnaires. The data analysis technique uses a paired t test. It was found that the majority of families of stroke patients were female (65,6%), aged 46-55 years (37.5%), had a high school education (53.1%), did not work or were housewives (53,1% ), and the family caring for the child (62.5%), before being given health education using leaflets related to the care of non-hemorrhagic post-stroke patients, the majority of family members were less prepared (62.5%) and after being given health education, the majority of family members feel ready (87,5%). There is an influence of health education regarding the care of stroke patients on the readiness to return home to the families of non-hemorrhagic stroke patients in the Inpatient Room at RSU PKU Muhammadiyah Delanggu (p value 0.000 < 0,05).

What is the significance of trunk muscle morphology in terms of balance? Structure vs function in chronic post-stroke patients. A cross-sectional study

Objective: To assess the architecture of the trunk muscles with RUSI and to reveal which parameters may be related to balance assessment tools in patients that suffered a stroke with hemiparesis. Methods: An observational, analytical, cross-sectional, matched case-control study was conducted, nested within a single-center cohort comprising patients with chronic hemiparesis. Twenty individuals in the chronic post-stroke stage and twenty healthy controls were recruited for this investigation. Key outcomes included the thickness measurements of the Rectus Abdominis (RA), External Oblique (OE), Internal Oblique (OI), Transversus Abdominis (TrAb), and Lumbar Multifidus (LMult) muscles, as well as assessments using the Modified Rivermead Functional Test (MRFT), Timed Up and Go (TUG), and BERG scales. Results: Results did not show statistically significant differences between groups for the outcomes measured. Conclusions: The findings indicate no significant disparities between the measured sides, suggesting that muscle alterations in patients that suffered a stroke may be more pronounced during the acute stage compared to the chronic stage. Keywords: Stroke, trunk, balance.

The Effect of Extremely Low-Frequency Magnetic Field on Stroke Patients: A Systematic Review.

The aim of this study was to review the current state of scientific evidence on the effect of extremely low-frequency magnetic fields stimulation (ELF-MFs) on stroke patients. A systematic review of PubMed, ScienceDirect, PeDro and Embase databases was conducted. Only articles published in English, involving adult participants and focusing on individuals who had experienced a stroke, specifically examining the impact of ELF-MFs on post-stroke patients and had well-defined criteria for inclusion and exclusion of participants, were included. The methodological quality of the included studies was assessed using the Quality Assessment Tool for Quantitative Studies (QATQS). A total of 71 studies were identified through database and reference lists' search, from which 9 were included in the final synthesis. All included studies showed a beneficial effect of ELF-MFs on stroke patients, however seven of the included studies were carried by the same research group. Improvements were observed in domains such as oxidative stress, inflammation, ischemic lesion size, functional status, depressive symptoms and cognitive abilities. The available literature suggests a beneficial effect of ELF-MFs on post-stroke patients; however, the current data are too limited to broadly recommend the use of this method. Further research with improved methodological quality is necessary.

Effects of extracorporeal diaphragm pacing combined with inspiratory muscle training on respiratory function in people with stroke: a randomized controlled trial

ABSTRACT Objectives To evaluate the effect of external diaphragmatic pacing (EDP) combined with inspiratory muscle training on respiratory function in post-stroke patients. Methods Patients with stroke were enrolled from the First Affiliated Hospital of Soochow University in China between 2021 and 2022. The patients were randomized into an EDP treatment group (control group) or an EDP treatment plus inspiratory muscle training group (experimental group). Each therapy was administered once a day for 6 days per week. The peak inspiratory flow (PIF), maximal inspiratory pressure (MIP), forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), FEV1/FVC% ratio, and diaphragm thickness and mobility were measured and compared between the two groups after 4 weeks. Results After 4 weeks of intervention, respiratory muscle function indicators including PIF (95% CI: 0.21–1.28, p = 0.008) and MIP (95% CI: 6.92–25.44, p = 0.001) significantly improved in the experimental group. Diaphragmatic thickness also significantly increased in the experimental group (p < 0.05), while diaphragmatic excursion showed no significant difference between the two groups. Additionally, FVC (95% CI: 0.14–1.14, p = 0.013) and FEV1 (95% CI: 0.20–1.06, p = 0.005) demonstrated a significant increase in the experimental group, whereas FEV1/FVC% (95% CI: −0.84 to 9.36, p = 0.099) exhibited no significant group difference. Conclusion EDP combined with inspiratory muscle training in individuals with stroke provides greater benefits than EDP alone in terms of respiratory function recovery, except for the parameters of diaphragmatic excursion and FEV1/FVC%.

Circulating levels of potential markers of ischemic stroke in patients with the different forms of atrial fibrillation and chronic heart failure

Atrial fibrillation (AF) is the most common abnormal type of heart rhythm (cardiac arrhythmia), which is considered the leading cause of stroke. There have been limited studies on the prognostic markers for atrial disease and AF-associated ischemic stroke, despite the high demand for this procedure in daily clinical practice to monitor disease course and assess risk of stroke in patients with AF and chronic heart failure (CHF). Thus, the aim of the present study was to evaluate the levels of serum biomarkers related to ischemic stroke in CHF patients with the different forms of AF. Forty-six patients with various types of AF (paroxysmal, persistent and permanent) with or without ischemic stroke were enrolled in the study, 36 clinically healthy donors served as a control. The levels of inducible nitric oxide synthase (iNOS), vascular endothelial growth factor (VEGF) and angiostatins (AS) were evaluated by western blot analysis in the serum. The levels of active matrix metalloproteinases (MMPs) were analysed by gelatin zymography. Elevated levels of iNOS were shown in patients with all AF forms as compared with control, but iNOS levels in post-ischemic patients were significantly higher than that in paroxysmal AF individuals. However, the levels of VEGF and AS did not differ from the baseline value in patients with paroxysmal AF, while dramatic increase of their contents was shown in post-stroke patients with persistent and permanent types of AF. Elevated active MMP-9 levels were shown to be associated with the diagnosis of all AF forms, regardless of the occurrence of stroke. Taken together, our findings­ demonstrate that tested proteins can be considered as valuable biomarkers of AF forms transformation and potentially useful for ischemic stroke risk stratification in patients with AF and CHF. Observed changes in regulatory protein levels may expand our understanding of pathological roles of endothelial function dysregulation, disrupted angiogenesis balance and abnormal tissue remodeling in AF and associated ischemic events. Keywords: angiostatins, atrial fibrillation, biomarkers, iNOS, ischemic stroke, MMP-9, VEGF

Soft Robotic Bilateral Rehabilitation System for Hand and Wrist Joints

Upper limb functionality is essential to perform activities of daily living. It is critical to investigate neurorehabilitation therapies in order to improve upper limb functionality in post-stroke patients. This paper presents a soft-robotic bilateral system to provide rehabilitation therapy for hand and wrist joints. A sensorized glove that tracks finger and wrist joint movements is worn on the healthy limb, which guides the movement of the paretic limb. The input of sensors from the healthy limb is provided to the soft robotic exoskeleton attached to the paretic limb to mimic the motion. A proportional derivative flow-based control algorithm is used to perform bilateral therapy. To test the feasibility of the developed system, two different applications are performed experimentally: (1) Wrist exercise with a dumbbell, and (2) Object pick-and-place task. The initial tests of the developed system verified its capability to perform bilateral therapy.

Study of the Possibility of Using Virtual Reality Application in Rehabilitation among Elderly Post-Stroke Patients.

Thanks to medical advances, life expectancy is increasing. With it comes an increased incidence of diseases, of which age is a risk factor. Stroke is among these diseases, and is one of the causes of long-term disability. The opportunity to treat these patients is via rehabilitation. A promising new technology that can enhance rehabilitation is virtual reality (VR). However, this technology is not widely used by elderly patients, and, moreover, the elderly often do not use modern technology at all. It therefore becomes a legitimate question whether elderly people will be able to use virtual reality in rehabilitation. This article presents a rehabilitation application dedicated to patients with upper limb paresis and unilateral spatial neglect (USN). The application was tested on a group of 60 individuals including 30 post-stroke patients with an average age of 72.83 years. The results of the conducted study include a self-assessment by the patients, the physiotherapist's evaluation, as well as the patients' performance of the exercise in VR. The study showed that elderly post-stroke patients are able to use virtual reality applications, but the ability to correctly and fully perform an exercise in VR depends on several factors. One of them is the ability to make logical contact (p = 0.0001 < 0.05). However, the study presented here shows that the ability to use VR applications does not depend on age but on mental and physical condition, which gives hope that virtual reality applications can be used in post-stroke rehabilitation among patients of all ages.

Feasibility of Computerized Visuomotor Integration System for Visual Field Defects and Spatial Neglect in Poststroke Patients.

To develop a computerized visuomotor integration system for assessment and training of visual perception impairments and evaluate its safety and feasibility in patients with a stroke. Visual field defects and spatial neglect lead to substantial poststroke impairment. Most diagnostic assessments are anchored in traditional methods, and clinical effects of rehabilitation treatments are limited. The CoTras Vision system included two evaluations and four training modules. The evaluation modules were based on the Albert's test and Star cancellation test, and training modules were based on visual tracking, central-peripheral integration, and visuomotor perception techniques. Bland-Altman plots for agreement with the traditional paper-and-pencil test were performed, and the modified Intrinsic Motivation Inventory, Patient Satisfaction Questionnaire, and Simulator Sickness Questionnaire were conducted. Ten patients with acute stroke completed the study. Bland-Altman plots revealed good agreements for Albert's test (mean difference, -0.3±4.5) and Star cancellation test (mean difference, 0.3±0.7). The mean±standard deviation scores of the modified Intrinsic Motivation Inventory, Patient Satisfaction Survey, and Simulator Sickness Questionnaire were 84.7±30.6, 40.5±7.9, and 34.0±34.5 respectively. The CoTras Vision system is feasible and safe in patients with stroke. Most patients had a high degree of motivation to use the system and did not experience severe adverse events. Further studies are needed to confirm its usefulness in stroke patients with visual field defects and hemineglect symptoms. Furthermore, a large, well-designed, randomized controlled trial will be needed to confirm the treatment effect of the CoTras Vision system.

Cognitive Disorders in Post-Stroke Patients

Blood circulation disorders in post-stroke patients can cause cognitive disorders. Cognitive disorders in post-stroke patients can include memory impairment, difficulty speaking, difficulty understanding things, difficulty communicating, and mood disorders. The presence of cognitive disorders in stroke patients can worsen the patient's post-stroke condition, requiring longer treatment time. This study aimed to identify the level of cognitive disorders in post-stroke patients. This research is a descriptive study to identify dementia in post-stroke patients. The sampling technique was accidental sampling for two weeks at the Neurology Polytechnic and Stroke Clinic at one of the hospitals in Bandung, totaling 83 people. The questionnaire used in this research was the Mini-Mental State Examination (MMSE). The collected data is analyzed and presented using frequency and percentage distributions. The results of this study showed that the majority of post-stroke patients (72.3%) did not experience dementia or did not experience cognitive impairment, 15.66% experienced mild cognitive impairment, and 12.04% experienced severe cognitive impairment. From the results of this study, it can be concluded that some post-stroke patients do not experience cognitive impairment, but some post-stroke patients experience severe cognitive impairment. Cognitive impairment in stroke patients can worsen the patient's condition and increase the length of treatment time. Based on the results of this research, health workers especially nurses, are expected to be able to carry out early assessments and provide particular interventions for post-stroke patients aimed at preventing the worsening of dementia and improving the patient's cognitive abilities. The intervention can be in the form of education, psychological support, and social support in the form of counseling during rehabilitation.

Dry needling combined with exercise therapy: Effects on wrist flexors spasticity in post-stroke patients - A randomized controlled trial.

The positive contribution of dry needling (DN) in conjunction with exercise therapy for patients with stroke and spasticity remains uncertain. To examine the effects of DN combined with exercise therapy on wrist flexor spasticity and motor function in patients with stroke. Twenty-four participants with stroke were randomly assigned to either the DN and exercise therapy group or the DN alone group. Assessments were conducted at baseline, after the 4th treatment session, and 3 weeks post-treatment. A significant Group×Time interaction was observed for wrist active range of motion (ROM) (P = 0.046), favoring the DN with exercise therapy group (∼10° at baseline, ∼15° immediately after the 4th session, and 15.4° at follow-up). The improvements in spasticity, passive ROM, and H-reflex latency were sustained during follow-up. However, there were no significant between-group differences in any outcome at any measurement time point. The combined DN and exercise therapy did not exhibit superiority over DN alone concerning spasticity severity and motor function. However, it demonstrated additional advantages, particularly in improving motor neuron excitability and wrist passive extension.

Increased trailing limb angle in hemiplegic patients after training with a knee orthosis: A randomized controlled trial.

Stroke often induces gait abnormality, such as buckling knee pattern, compromising walking ability. Previous studies indicated that an adequate trailing limb angle (TLA) is critical for recovering walking ability. We hypothesized that correcting gait abnormality by immobilizing the knee joint using a knee orthosis (KO) would improve walking patterns and increase the TLA, and investigated whether walking training using a KO would increase the TLA in post-stroke patients. In a randomized controlled trial, thirty-four participants were assigned to KO (walking training using a KO) and non-KO (without using a KO) groups. Twenty-nine completed the three-week gait training protocol. TLA was measured at baseline and after training. A two-way repeated ANOVA was performed to evaluate TLA increases with training type and time as test factors. A t-test compared TLA changes (ΔTLA) between the two groups. ANOVA showed a main effect for time (F = 64.5, p < 0.01) and interaction (F = 15.4, p < 0.01). ΔTLA was significantly higher in the KO group (14.6±5.8) than in the non-KO group (5.0±7.0, p < 0.001). Walking training using a KO may be practical and effective for increasing TLA in post-stroke patients.

Impaired oral status is associated with sarcopenic obesity in post-stroke patients.

Oral problems and muscle health are indeed significant concerns in ageing populations. However, there is limited evidence concerning the association between these issues. The study's focus was to investigate the association between oral problems and sarcopenic obesity, wherein sarcopenia and obesity coexist concurrently, in post-stroke patients. This retrospective, observational, cross-sectional study included patients hospitalised for post-stroke rehabilitation. Oral problems were assessed using the Revised Oral Assessment Guide (ROAG). Sarcopenic obesity was diagnosed according to the European Society of Clinical Nutrition and Metabolism/European Association for the Study of Obesity criteria. Multiple linear regression analysis was used to examine the association between the ROAG and sarcopenic obesity after adjusting for confounding factors. A total of 760 patients were included, with a mean (SD) age of 71 (9) years, of whom 408 (54.7%) were male. The median (interquartile range, 25th and 75th percentiles) ROAG was 11 [9, 13]. Sarcopenic obesity was diagnosed in 16 (3.9%) men, 18 (5.1%) women, and 34 (4.5%) patients overall. Multivariate linear analysis showed that ROAG was significantly and positively associated with sarcopenic obesity (β = .091, P = .023), followed by obesity alone (β = .084, P = .044), and sarcopenia alone (β = .081, P = .037). Oral problems were associated with sarcopenic obesity in post-stroke. Oral assessment and intervention may have a positive impact on ADL and QOL in post-stroke patients with sarcopenic obesity.

0915 Actual Condition Survey of Obstructive Respiratory Events in Convalescent Post-stroke Patients with Dysphagia

0915 Actual Condition Survey of Obstructive Respiratory Events in Convalescent Post-stroke Patients with Dysphagia

A Sensor-Based Upper Limb Treatment in Hemiplegic Patients: Results from a Randomized Pilot Study.

In post-stroke patients, the disabling motor deficit mainly affects the upper limb. The focus of rehabilitation is improving upper limb function and reducing long-term disability. This study aims to evaluate the feasibility of using the Gloreha Aria (R-Lead), a sensor-based upper limb in-hospital rehabilitation, compared with conventional physiotherapist-led training in subacute hemiplegic patients. Twenty-one patients were recruited and randomised 1:1 to a sensor-based group (treatment group TG) or a conventional group (control group, CG). All patients performed 30 sessions of 30 min each of dedicated upper limb rehabilitation. The Fugl-Meyer Assessment for Upper Extremity (FMA-UE) was the primary evaluation., both as a motor score and as individual items. Secondary evaluations were Functional Independence Measure; global disability assessed with the Modified Barthel Index; Motor Evaluation Scale for UE in stroke; power grip; and arm, shoulder, and hand disability. All the enrolled patients, 10 in the TG and 11 in the CG, completed all hand rehabilitation sessions during their hospital stay without experiencing any adverse events. FMA-UE scores in upper limb motor function improved in both groups [delta change CG (11.8 ± 9.2) vs. TG (12.7 ± 8.6)]. The score at T1 for FMA joint pain (21.8 vs. 24 best score) suggests the use of the Gloreha Aria (R-Lead) as feasible in improving arm function abilities in post-stroke patients.

Dysphagia in Ischaemic Stroke Patients: One Centre Retrospective Study.

The aim of this study was to examine the frequency of dysphagia in patients with ischaemic stroke. It was crucial to evaluate the relationship between swallowing disorders and selected demographic and clinical indicators. Additionally, the association between various patient feeding methods and selected demographic and clinical factors was assessed. Based on the analysis of medical documentation, we identified the most important clinical parameters, including demographic data, the frequency of stroke risk factors, the location of the ischaemic lesion, cortical involvement, stroke severity as measured by the NIHSS (Nationale Institutes of Health Stroke Scale), and the methods of feeding post-stroke patients. Dysphagia was observed in 65.9% of the patients in the study group. Hypertension was the most common chronic illness in the studied population of ischemic stroke patients (91.8% of patients). Diet modification (35.7%) and PEG (25%) were the frequent methods of feeding in patients with confirmed dysphagia. Age played a significant role in determining the feeding methods in patients with dysphagia. Patients with a PEG (Percutaneous Endoscopic Gastrostomy) tube were the oldest (79.37 ± 10.80) and 75% of them had pneumonia. Early identification of swallowing difficulties in stroke patients is critical in determining an appropriate and safe feeding plan, as well as initiating logopedics therapy to improve swallowing efficacy and minimize pulmonary complications.

Effects of ankle–foot orthoses on gait parameters in post-stroke patients with different Brunnstrom stages of the lower limb: a single-center crossover trial

BackgroundAnkle-foot orthoses (AFO) can improve gait posture and walking ability in post-stroke patients. However, the effect of AFO on gait parameters in post-stroke patients according to the Brunnstrom stage of stroke recovery of the lower limbs remains unclear. The study aimed to investigate whether stroke patients with different Brunnstrom stages benefit from wearing AFO.MethodsTwenty-five post-stroke participants included 18 men (50 ± 13 years) and 7 women (60 ± 15 years). The patients were divided based on Brunnstrom stage III or IV of the lower limbs. All patients underwent the gait and timed up and go (TUG) test using a gait analysis system while walking barefoot or with an AFO. The spatiotemporal and asymmetric parameters were analyzed.ResultsAll 25 patients completed the study. Significant differences were observed between barefoot and AFO use in TUG time (P < 0.001) but not walking velocity (P > 0.05). The main effect of the swing time ratio was significant in both groups (P < 0.05); however, the main effects of stride length, stance time, and gait asymmetry ratio were nonsignificant (P > 0.05). For barefoot versus AFO, the main effects of stride length (P < 0.05) and swing time (P < 0.01) ratios were significant, whereas those of stance time and gait asymmetry ratio were nonsignificant (P > 0.05).ConclusionsPost-stroke patients with lower Brunnstrom stages benefitted more from AFO, particularly in gait asymmetry.

Expert opinion on stroke management: An Indian observational study

: Stroke is the leading cause of long-term disability and one of the top causes of mortality worldwide. The burden in India has been increasing at an alarming rate over the past few decades. India with its culturally diverse environment and economically developing status presents unique challenges in stroke management. This study is an initiative designed to gain a better understanding of stroke prevalence and therapy in India. : A cross-sectional questionnaire-based study among Indian Cardiologists was conducted. A convenient sampling method was used. About 34% of doctors said that acute stroke is most prevalent in the age group of 41- 50 years in their clinical setup. The study results also highlight that piracetam 800mg is the preferred effective option for age-related cognitive disorders. Some of them preferred Piracetam for vertigo of mixed origin, vestibular, and other associated disorders of vertiginous attacks. 51% of doctors observed that vertigo is diagnosed more frequently among both genders, more common in the age group of 21-30 years. 93% of doctors agreed that piracetam improves cognitive improvement post-surgery. Three-fourths of doctors who participated in the survey rated 45% of doctors prescribed the combination of piracetam and citicoline in post-stroke recovery patients. Also, 40% of them prescribed neuroprotective agents to 51-70% of stroke patients. This study demonstrated that the stroke prevalence rate is high among patients above 40 years of age. Piracetam 800 mg is commonly prescribed to most of the stroke patients. Half of the respondents felt that there was a significant improvement in cognitive decline with piracetam. This study's findings highlight that piracetam is an effective option for age-related cognitive disorders.