Due to the specific characteristics of synthetic aperture radar (SAR), there will be ambiguity interference in SAR images, resulting in low contrast of the ship target to the clutter. This letter proposes an improved super-resolution generative adversarial network (ISRGAN) based ambiguity suppression algorithm for SAR ship target contrast enhancement. The proposed ISRGAN is the first attempt of using GAN for SAR ambiguity suppression. As a post-processing procedure, it does not need prior information of SAR systems, so it can be applied to various observation scenes and different acquisition modes. The generator of ISRGAN embeds the residual dense network (RDN) to optimally fuse the global and local features of the image, and it effectively improves the completeness of the feature information used for SAR ship target contrast enhancement. The superiority of ISRGAN on ambiguity suppression is validated on the Chinese Gaofen-3 imagery.