Effective support of emergency materials is a necessary prerequisite for post-disaster emergency rescue. The transportation and distribution of post-disaster emergency materials includes two stages: from storage warehouses and material distribution centers outside the disaster area to emergency distribution centers outside the disaster area, and from emergency distribution centers to rescue points in the disaster area. Emergency material support has the characteristics of urgent demand and relative shortage of materials. Especially, the transportation of materials from supply points outside the disaster-stricken areas to emergency material distribution centers, along the way, affected by the actual traffic capacity and meteorological conditions, will have a significant impact on the efficient distribution of emergency materials. This paper deals with the optimization of transportation allocation from emergency material supply points to emergency material distribution centers in the periphery of disaster areas. Based on the factors affecting transportation efficiency such as road resistance parameters, attenuation coefficient, and disaster intensity, an optimal allocation model of emergency materials is established, which minimizes the sum of transportation cost, construction cost of distribution center, and penalty cost of transportation time. The validity and feasibility of the model are analyzed and studied by an example. The experimental results show that the attenuation coefficient of the transportation line and the disaster intensity of the road section have important influence on the emergency material allocation scheme. The emergency material allocation scheme formulated by the optimization model is scientific and reasonable.