Municipal solid waste (MSW) has huge potential to be recycled as construction material, which would have significant benefits for environmental conservation. However, the cornerstone of this undertaking is a solid comprehension of the mechanical response of MSW in real-world engineering locations, taking into account the effects of stress levels and temperature. In this paper, well-mixed MSW samples were sieved and crushed to produce standardized specimens in cylindrical molds. A series of static, dynamic, and post-cyclic shear tests were conducted on the MSW at temperatures ranging from 5 °C to 80 °C with normal stresses of 50 kPa, 100 kPa, and 150 kPa. The experimental findings demonstrate that the static, dynamic, and post-cyclic mechanical response of MSW presents temperature range-dependency; temperature variation between 5 °C and 20 °C affects MSW's mechanical reaction more than variation in temperature between 40 °C and 80 °C under various stress settings; at 5 °C~80 °C, the static peak shear strength of MSW is the highest, being followed by the post-cyclic peak shear strength, while the dynamic peak shear strength is the lowest; the sensitivity of the dynamic shear strength of MSW to temperature variation is the largest, being followed by the post-cyclic peak shear strength, and the static peak shear strength is the lowest.