Experimental and theoretical results are presented for electron impact ionization of water in the energy regime from near threshold to intermediate energies. Results were taken in symmetric coplanar and non-coplanar geometries, with both equal and non-equal outgoing electron energies. The models approximate the random orientation of the target using a spherical averaging of the wavefunction prior to the collision, using sophisticated distorted wave Born calculations that include post-collisional interactions in first order and to all orders of perturbation theory. The calculations predict the data most accurately at the lowest energy studied (4 eV above threshold) in a coplanar symmetric geometry, whereas the comparison between theory and experiment is generally marginal for higher energies and for non-coplanar geometries.