Positive Effect Research Articles

“I’m both smoking and vaping”: a longitudinal qualitative study of US young adults who tried to quit smoking cigarettes by using electronic cigarettes

ObjectiveTo describe how young adults use electronic cigarettes (electronic nicotine delivery systems (ENDS)) for smoking cessation and reasons why they may or may not successfully quit smoking.MethodsLongitudinal qualitative data were...

Validation of Cool-Season Snowfall Forecasts at a High-Elevation Site in Utah’s Little Cottonwood Canyon

Abstract Producing a quantitative snowfall forecast (QSF) typically requires a model quantitative precipitation forecast (QPF) and snow-to-liquid ratio (SLR) estimate. QPF and SLR can vary significantly in space and time over complex terrain, necessitating fine-scale or point-specific forecasts of each component. Little Cottonwood Canyon (LCC) in Utah’s Wasatch Range frequently experiences high-impact winter storms and avalanche closures that result in substantial transportation and economic disruptions, making it an excellent testbed for evaluating snowfall forecasts. In this study, we validate QPFs, SLR forecasts, and QSFs produced by or derived from the Global Forecast System (GFS) and High-Resolution Rapid Refresh (HRRR) using liquid precipitation equivalent (LPE) and snowfall observations collected during the 2019/20–2022/23 cool seasons at the Alta–Collins snow-study site (2945 m MSL) in upper LCC. The 12-h QPFs produced by the GFS and HRRR underpredict the total LPE during the four cool seasons by 33% and 29%, respectively, and underpredict 50th, 75th, and 90th percentile event frequencies. Current operational SLR methods exhibit mean absolute errors of 4.5–7.7. In contrast, a locally trained random forest algorithm reduces SLR mean absolute errors to 3.7. Despite the random forest producing more accurate SLR forecasts, QSFs derived from operational SLR methods produce higher critical success indices since they exhibit positive SLR biases that offset negative QPF biases. These results indicate an overall underprediction of LPE by operational models in upper LCC and illustrate the need to identify sources of QSF bias to enhance QSF performance. Significance Statement Winter storms in mountainous terrain can disrupt transportation and threaten life and property due to road snow and avalanche hazards. Snow-to-liquid ratio (SLR) is an important variable for snowfall and avalanche forecasts. Using high-quality historical snowfall observations and atmospheric analyses, we developed a machine learning technique for predicting SLR at a high mountain site in Utah’s Little Cottonwood Canyon that is prone to closure due to winter storms. This technique produces improved SLR forecasts for use by weather forecasters and snow-safety personnel. We also show that current operational models and SLR techniques underforecast liquid precipitation amounts and overforecast SLRs, respectively, which has implications for future model development.

Parenthood and gender inequality on labor market outcomes: Evidence from South Korea

AbstractThis study estimates the long‐term effect of parenthood on labor market outcomes and explores the variations within this effect by gender and education. We use the event study method to track changes in a range of labor market outcomes from 3 years before to 8 years after the first birth, with a sample of 556 married women and 528 married men from the Korea Labor and Income Panel Study (KLIPS). We find that women experience an immediate drop in wages following birth, whereas men experience continuous wage growth even before birth. The decline in women's wages arises largely from their withdrawal from the labor market, while the increase in men's wages could be explained by a positive selection bias among fathers. In addition, mothers' wage trajectories do not vary significantly by education level, whereas other labor market outcomes show discernible trends. These patterns are the opposite of those observed for men. The findings indicate that severe gender inequality in the Korean labor market lowers the wages of mothers, regardless of their education, while the wages of fathers are more likely to be affected by education. Based on the findings, we make policy suggestions for improving the work‐family balance for all genders.

Evaluating Drawings’ Creativity: Synchrony Effects on Rater Bias and the Mediating Role of Emotional Arousal

ABSTRACT Creativity evaluation, particularly rating the creativity of products, is an unstable construct subjective to the influence of various individual states and characteristics. However, little research has been conducted on whether and how participants’ physiological states affect rating products. This experimental study aimed to explore how synchrony (i.e. whether individuals’ evaluation time synchronizes with their peak circadian arousal periods during a day) affects the rating of creativity in drawings, whether these effects vary according to drawings’ different creativity levels, and the influence of emotional state on synchrony and creativity rating. A sample of 191 university students rated several drawings of low, medium, and high creativity levels at their optimal or non-optimal times of day, and their subjective emotional valence and arousal were recorded. The results showed that participants exhibited a more positive rater bias when rating low- and medium-creativity-level drawings during their optimal times of day. Emotional arousal, but not valence, mediated the relationship between synchrony and rater bias. These findings highlight the role of synchrony and emotional arousal in rating creative products, contributing to our understanding of how raters’ synchrony states influence creativity evaluation.

Divergent Transformation of Wet to Cold Bias on the Tibetan Plateau in Climate Models During Snow Season

AbstractWet and cold biases on the Tibetan Plateau (TP) commonly exist in global and regional climate simulations. Previous studies have explored the possible causes of wet and cold biases and contributed to reducing these biases. However, the connection between wet and cold biases remains insufficiently addressed. Our research indicates that the TP wet bias converts into positive snow amount bias not continually but efficiently and concentratedly, under the control of snow phenology in different regions. Furthermore, the complex relationship between snow amount, snow coverage and surface albedo restricts the transformation of snow amount to surface albedo bias, and thus to cold bias. Our research highlights the spatio‐temporally divergent transformation of wet to cold bias on the TP during snow season, providing a novel perspective to understand the intrinsic connection between wet and cold biases and improve climate simulations on the TP.

Viable Approach of Tuning Oxide Semiconductor Thin Films in Solution‐Processed Heterojunction Thin Films Transistors for Both Higher Performances and Stability

AbstractMetal‐oxide thin‐film transistors (TFTs) have garnered much attention because of their advantages such as high transparency, low leakage current, and low processing temperature. However, there is a need to continuously improve their mobility and bias stability for application to next‐generation advanced electronics. In this study, the thickness of bilayer semiconductors is finely controlled to enhance the charge transport characteristics and bias stability in solution‐processed heterojunction oxide TFTs. The thicknesses of the top and bottom layers in the bilayer are individually adjusted by controlling solution molarity. The introduction of a bilayer channel improved the electrical performance of oxide TFTs via effective charge transport. However, trap‐limited conduction becomes dominant in the bilayer with an excessively thick top layer, thereby leading to a significant reduction in mobility and positive bias stability. Meanwhile, although increasing the bottom layer thickness contributes to improved mobility and reliability, it causes a serious negative shift in threshold voltage (VTH). TFTs with an optimized bilayer structure show high mobility at a VTH close to 0 V and have particularly excellent positive bias stress stability. This study on bilayer channel thickness will be beneficial for developing advanced transistors with optimized bilayer or multilayer channels.

A Systematic Review and Meta-Analysis of Anxiety- and Depressive-Like Behaviors in Rodent Models of Neuropathic Pain

BackgroundEpidemiological studies have frequently shown the concurrence of chronic pain with symptoms of anxiety and depression, particularly in women. Animal models are useful to understand the complex mechanisms underlying comorbidities, but the wide range of methods employed and the wealth of evidence sometimes impedes effective translation and reproducibility. In this systematic review and meta-analysis, we aimed to synthesize the evidence regarding the influence of variables such as sex and species on anxiety- and depressive-like behaviors in rodent models of neuropathic pain. MethodsFollowing PROSPERO registration, we searched EMBASE, Scopus, and the Web of Science from their inception to November 24, 2023, identifying 126 studies that met the inclusion criteria. The Hedges’ g value for each experiment and study was calculated, and further subgroup and meta-regression analyses were performed. ResultsNeuropathic pain significantly reduced the time that rats and mice spent in the open arms of the elevated plus and zero mazes (g = −1.14), time spent in the center of the open field (g = −1.12), sucrose consumption in the sucrose preference test (g = −1.43), and grooming time in the splash test (g = −1.37) while increasing latency to feed in the novelty-suppressed feeding test (g = 1.59) and immobility in the forced swimming (g = 1.85) and tail suspension (g = 1.91) tests. Sex differences were observed, with weaker effects in female than in male rodents for several behavioral paradigms, and funnel plots identified positive publication bias in the literature. ConclusionsThis meta-analysis emphasizes the effect of neuropathic pain on anxiety- and depressive-like behaviors in rodents, highlighting the importance of investigating sex differences in future experimental studies.

Pengaruh Leverage, Profitability, Sales Growth, Age, Size dan Institutional Ownership terhadap Tax Avoidance

Tax Avoidance is defined as a legal activity (efforts made by taxpayers to minimize the tax burden).The objective of this research is to obtain empirical evidence regarding the influence of Leverage, Profitability, Sales Growth, Size, Age and Institutional Ownership (variable X) on Tax Avoidance (variabel Y) with the object of research on manufakturing companies listed on the indonesian Stock Exchange (IDX) from 2019 – 2021 years.The population in this study was obtained using sampling technique with purposive sampling method where this study amounted to 195 company data. The results of this study explain that Sales Growth, Age, Size, and Institutional Ownership have no effect on Tax Avoidance. While Leverage positif effect and Profitability Negative effect on Tax Avoidance.

Development and Validation of a Novel Isotope Dilution-Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry Method for Serum C-Peptide.

Mass spectrometry (MS) methods exhibit higher accuracy and comparability in measuring serum C-peptide concentrations than immunoassays. We developed and validated a novel isotope dilution-ultraperformance liquid chromatography-tandem MS (ID-UPLC-MS/MS) assay to measure serum C-peptide concentrations. Sample pretreatment involved solid-phase extraction, ion-exchange solid-phase extraction, and derivatization with 6-aminoquinolyl-N-hydroxysuccinimidylcarbamate (Cayman Chemical, Ann Arbor, Michigan, USA). We used an ExionLC UPLC system (Sciex, Framingham, MA, USA) and a Sciex Triple Quad 6500+ MS/MS system (Sciex) for electrospray ionization in positive-ion mode with multiple charge states of [M+3H]3+ and multiple reaction monitoring transitions. The total run time was 50 mins, and the flow rate was 0.20 mL/min. We evaluated the precision, trueness, linearity, lower limit of quantitation (LLOQ), carryover, and matrix effects. Method comparison with electrochemiluminescence immunoassay (ECLIA) was performed in 138 clinical specimens. The intra- and inter-run precision coefficients of variation were <5% and the bias values for trueness were <4%, which were all acceptable. The verified linear interval was 0.050-15 ng/mL, and the LLOQ was 0.050 ng/mL. No significant carryover or matrix effects were observed. The correlation between this ID-UPLC-MS/MS method and ECLIA was good (R=0.995, slope=1.564); however, the ECLIA showed a positive bias (51.8%). The developed ID-UPLC-MS/MS assay shows acceptable performance in measuring serum C-peptide concentrations. This will be useful in situations requiring accurate measurement of serum C-peptide in clinical laboratories.

Development and evaluation of a blended learning training programme for pharmacy technicians’ continuing education

ObjectivesThe role of the pharmacy technician (PT) has expanded in recent years, requiring new competencies, better communications skills and high-level knowledge about drugs. The objective of this study is to...

Hematological parameters of lactating cows when use the feed additives Live protein and Tanrem Sh

The purpose of the research was to study the hematological parameters of lactating cows when use the feed additives Live protein and Tanrem Sh. The scientific and economic experiment was carried out at the breeding farm of Razliv LLC in the Kurgan region on 30 matured lactating cows of Blackand- White breed. Animals were selected into groups using the analog method, taking into account age, live weight, calving date, and productivity. The experiment was carried out during 2022–2023. Analyzing changes in individual blood parameters, a tendency towards an increase in erythrocytes in the experimental groups by 14.62–14.82 % was observed, compared to the control group). At the same time,erythrocytes in animals of the experimental groups were more saturated with hemoglobin. For example, if in the control group the hemoglobin content in erythrocytes was at the level of 92.03 g/l, then in the experimental groups its quantity was 101.16–11.44 g/l or 9.92–10.22 % higher. The content of leukocytes in all groups was from 7.55 to 8.19×109/l, with the maximum permissible value of 12.0×109/l. The content of lymphocytes in animals of the experimental and control groups did not have large deviations and was from 4.58 to 5.08×109/l with the norm from 2.5 to 7.5×109/l. Eosinophils are an indicator of allergic processes. Their content was also within the permissible norms and was from 7.50 to 8.90 %. Thus, the inclusion of the additives Live protein and Tanrem Sh in the ration of lactating cows had a positive eff ect on hematological parameters. The increase in the number of erythrocytes with increased hemoglobin saturation compared to the control group indicates more intensive metabolic processes in the animals’ bodies.

Infl uence of the exercise regime on the quality indicators of sperm production in breeding boars

In the pig breeding industry, the quality of sperm obtained from breeding boars plays an important role in the issue of reproduction. The purpose of the research was to investigate the eff ect of exercise regime on the quality indicators of sperm production in breeding boars. The research was carried out at the Tyumensky Pig Complex LLC in the Tyumen Region. For the research 3 groups of boars were formed with 10 heads in each. The control group did not receive exercise, the 1st experimental group received passive exercise, the 2nd experimental group received active exercise. It was found that the rectilinear motility of sperm, which aff ects the fertilizing ability of semen was in the 1st experimental group of boars 87.0 %, which was by 2.8 abs.% higher than in other groups. Also, more sperm doses were obtained from semen with high rectilinear motility with the same volume and concentration indicators In the groups of boars without exercise and with active exercise, 5.7 % of dead sperm were found, which was by 0.8 abs.% more than in the analogs that received passive exercise (p &lt; 0,05). In the 1st experimental group of boars with passive exercise, the lowest percentage of sperm with defects was found, which aff ects the efficiency of insemination and the quality of the off spring. It was found that passive exercise had a more favorable eff ect on the qualitative indicators of sperm of the breeding boars of the 1st experimental group compared to active exercise (2nd experimental group) and its absence (control group). The use of passive exercise regime for breeding boars had a positive eff ect not only on the quantitative indicators of semen, but also on the quality of sperm and can be recommended at the enterprise when housing breeding boars.

Adolescents' trait mindfulness and psychological stress: The mediating role of attention.

Based on the Combined Cognitive Biases Hypothesis, the current study via two parallel studies aims to explore the potential mediating role of attention biases and attention control regarding the link between trait mindfulness and psychological stress in adolescents. For Study 1, we collected self-reported data from 2123 Chinese adolescents (mean age = 15.6 years, SD = 2.37; 52.8% female) in four schools. The participants completed measures of trait mindfulness, perceived stress, and attention bias. Mediation analysis was employed to investigate the potential mediating effect of attention bias. In Study 2, 123 participants (mean age = 17.7 years, SD = 2.68; 41.46% female) completed the attention network task after inducing attention bias. Then, trait mindfulness and perceived stress were measured. Mediation analysis was employed to investigate the potential mediating effect of attention control (alerting, orienting, and conflict monitoring) under attention bias. Study 1 demonstrated a significant mediating effect of negative attention bias ([-0.13, -0.07], p < .05) but not positive attention bias in the relationship between trait mindfulness and psychological stress. Study 2 revealed that conflict monitoring in negative attention bias ([-0.41, -0.16], p < .05), rather than alerting and orienting in negative attention bias, showed a significant mediating effect on the association between trait mindfulness and psychological stress. Findings from the two studies suggest that conflict monitoring during negative attention bias may be the underlying mechanism through which trait mindfulness helps mitigate psychological stress in adolescents.

Sample comparison of BÜHLMANN fCAL Turbo and OC-FCa faecal calprotectin methods.

Faecal calprotectin is an inflammatory marker used to triage patients for further investigation with suspected inflammatory bowel disease (IBD). Our current method requires faecal samples be sent to the laboratory, where calprotectin is extracted before analysis. This is a time-consuming, potential bottleneck in the pathway. We have recently evaluated the OC-SENSOR PLEDIA fCAL method that uses the same sampling device as used in some bowel cancer screening and symptomatic colorectal cancer programmes that detect faecal haemoglobin. The below study is a comparison of the OC-FCa method with the BÜHLMANN fCAL Turbo which is used routinely within BSPS. 150 homogenised and 110 non-homogenised faecal samples were loaded into OC-Sampling Bottle 3 and BÜHLMANN CALEX cap sampling devices. The samples were then analysed on their respective systems according to manufacturer's instructions. The OC-FCa assay had a mean positive bias of 67.3% (homogenised) and 88.4% (non-homogenised). Homogenised samples showed substantial agreement between the methods for normal (<50µg/g) and elevated (150+µg/g) risk categories (k = 0.794, k = 0.788, respectively) and moderate agreement for borderline (51-150µg/g) (k = 0.25) according to the current Berkshire and Surrey Pathology Service (BSPS) guidelines. Non-homogenised samples had none to slight agreement for normal and borderline values (k = 0.02 for both) and moderate agreement for elevated (k = 0.596). The OC-FCa method is a viable alternative for faecal calprotectin testing, but requires an adjustment to clinical cut-off values due to the lack of standardisation and strong positive bias. A clinical comparative study is required to assess the impact of patients collecting their own samples into the devices, as this may negate any potential degradation samples may exhibit during transit to the laboratory.

Plasma-enhanced atomic layer deposition of Sn-doped indium oxide semiconductor nano-films for thin-film transistors

Sn-doped indium oxide (ITO) semiconductor nano-films are fabricated by plasma-enhanced atomic layer deposition using trimethylindium (TMIn), tetrakis(dimethylamino)tin (TDMASn), and O2plasma as the sources of In, Sn and O, respectively. A shared temperature window of 150 °C- 200 °C is observed for the deposition of ITO nano-films. The introduction of Sn into indium oxide is found to increase the concentration of oxygen into the ITO films and inhibit crystallization. Furthermore, two oxidation states are observed for In and Sn, respectively. With the increment of interfaces of In-O/Sn-O in the ITO films, the relative percentage of In3+ions increases and that of Sn4+decreases, which is generated by interfacial competing reactions. By optimizing the channel component, the In0.77Sn0.23O1.11thin-film transistors (TFTs) demonstrate high performance, includingμFEof 52.7 cm2V-1s-1, and a highION/IOFFof ∼5 × 109. Moreover, the devices show excellent positive bias temperature stress stability at 3 MV cm-1and 85 °C, i.e. a minimalVthshift of 0.017 V after 4 ks stress. This work highlights the successful application of ITO semiconductor nano-films by ALD for TFTs.

Assessing the Tropospheric Temperature and Humidity Simulations in CMIP3/5/6 Models Using the AIRS Obs4MIPs V2.1 Data

AbstractIn this study, the Atmospheric Infrared Sounder (AIRS) Observations for Model Intercomparison Projects (Obs4MIPs) V2.1 tropospheric air temperature, specific humidity, and relative humidity data are utilized to evaluate the global tropospheric temperature and humidity simulations in the fully coupled global climate models from the Coupled Model Intercomparison Project phases 3, 5, and 6 (CMIP3, CMIP5, and CMIP6), and possible simulation improvement in CMIP6 models in comparison to CMIP3 and CMIP5 models. Our analyses indicate that all three phases of CMIP models share similar tropospheric air temperature, specific humidity, and relative humidity biases in their multi‐model ensemble means relative to AIRS. Cold biases up to 4 K and positive relative humidity biases up to 20% are found in the free troposphere almost globally with maxima over the mid‐latitude storm tracks. Warm biases up to 2 K are seen over the Southern Ocean in the lower troposphere. Positive specific and relative humidity biases exist over the off‐equatorial oceans while negative specific and relative humidity biases are seen near the equator in the tropical free troposphere, which are related to the double‐intertropical convergence zone bias in the models. Both the air temperature and specific humidity biases are important to the relative humidity biases except in the tropical free troposphere where the specific humidity biases dominate. The tropospheric air temperature, specific humidity, and relative humidity biases are reduced from CMIP3 to CMIP5 and to CMIP6 at almost all pressure levels except at 300 hPa for specific humidity and in the boundary layer for relative humidity.

Impacts of Social Media Advertising on Purchase Intention and Customer Loyalty in E-Commerce Systems

The emergence of new technologies has had a noteworthy impact on communication systems, leading to the importance of conducting research in this area due to the significant influence of social media. Marketing operators must implement the necessary infrastructure to identify and fulfill customers' expectations, considering the advantages and the increasing number of users in social networks. This paper presents a comprehensive framework for evaluating the purchase intention of electronic commerce systems, taking into account the impact of social media advertising and customer loyalty. The paper aims to enhance purchase intention in e-commerce through social media advertising and examine influential factors that improve online shopping performance, including social media advertising's effectiveness on customer purchase behavior and brand loyalty. The paper develops a theoretical framework of nine hypotheses to evaluate purchase intention in e-commerce systems, with a focus on the effect of social media advertising on brand loyalty and purchase intention. To validate the proposed model and test the research hypotheses, we make use of information obtained from an international company located in China. The results demonstrate the positive effect of pleasurable motivation on purchase intention, with a significance level of 3.776 and a path coefficient of 0.279. Moreover, an investigation of the positive effect of customer loyalty on the recommended advertisement confirms the hypotheses, with a significance of 32.815 and a path coefficient of 0.788.

WATERHYPERNET: a prototype network of automated in situ measurements of hyperspectral water reflectance for satellite validation and water quality monitoring

This paper describes a prototype network of automated in situ measurements of hyperspectral water reflectance suitable for satellite validation and water quality monitoring. Radiometric validation of satellite-derived water reflectance is essential to ensure that only reliable data, e.g., for estimating water quality parameters such as chlorophyll a concentration, reach end-users. Analysis of the differences between satellite and in situ water reflectance measurements, particularly unmasked outliers, can provide recommendations on where satellite data processing algorithms need to be improved. In a massively multi-mission context, including Newspace constellations, hyperspectral missions and missions with broad spectral bands not designed for “water colour”, the advantage of hyperspectral over multispectral in situ measurements is clear. Two hyperspectral measurement systems, PANTHYR (based on the mature TRIOS/RAMSES radiometer) and HYPSTAR® (a newly designed radiometer), have been integrated here in the WATERHYPERNET network with SI-traceable calibration and characterisation. The systems have common data acquisition protocol, data processing and quality control. The choice of validation site and viewing geometry and installation considerations are described in detail. Three demonstration cases are described: 1. PANTHYR data from two sites are used to validate Sentinel-2/MSI (A&amp;amp;B); 2. HYPSTAR® data at six sites are used to validate Sentinel-3/OLCI (A&amp;amp;B); 3. PANTHYR and HYPSTAR® data in Belgian North Sea waters are used to monitor phytoplankton parameters, including Phaeocystis globosa, over two 5 month periods. Conclusion are drawn regarding the quality of Sentinel-2/MSI and Sentinel-3/OLCI data, including indications where improvements could be made. For example, a positive bias (mean difference) is found for ACOLITE_DSF processing of Sentinel-2 in clear waters (Acqua Alta) and clues are provided on how to improve this processing. The utility of these in situ measurements, even without accompanying hyperspectral satellite data, is demonstrated for phytoplankton monitoring. The future evolution of the WATERHYPERNET network is outlined, including geographical expansion, improvements to hardware reliability and to the measurement method (including uncertainty estimation) and plans for daily distribution of near real-time data.

Performance evaluation and characterization of pre-analytical effects by sample types and storage conditions on tumor marker measurement by the point-of-care test platform IchromaTM II

Tumor markers should be measured regularly and accurately to prevent, diagnose, and monitor cancers efficiently. We aimed to characterize the pre-analytical factors effecting on the analytical performance of point-of-care test (POCT) platform IchromaTM II (Boditech Med Inc., Gangwon-do, Korea) for alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), and prostate specific antigen (PSA) and evaluate their consequences in clinical practice. Based on comprehensive evaluation for the analytical performance of IchromaTM II including precision, linearity, and method comparison performed according to CLSI guidelines, pre-analytical factors of sample types and conditions were extensively analyzed. A total of five sample types [serum, plasma (PL) and whole blood (WB) from EDTA tube, PL and WB from sodium heparin tube] from 40 patients were used for comparing among specimen types. Additionally, stability was assessed up to 21 h at room temperature, refrigerated for 8 days, and frozen for 16 weeks by using 4 levels of pooled patient samples which were measured in triplicate. Precision, linearity and correlation with central laboratory analyzers observed in all three tumor markers were within acceptable criteria. However, variable degrees of percent deviations were observed according to sample type and storage conditions. Only EDTA PL samples presented clinically acceptable percentage biases for all three tumor markers when stored at room temperature or refrigerated condition. Positive bias of CEA and PSA in storage duration until 16 weeks were observed when stored in frozen condition. While IchromaTM II showed an adequate analytical performance as a POCT platform with simple operating procedures for the measurement of tumor markers, clinical laboratories should be aware of stability issues when different types of blood specimens are practically utilized.

Reliable Operation in High-Mobility Indium Oxide Thin Film Transistors.

Transparent oxide semiconductors (TOSs) based thin-film transistors (TFTs) that exhibit higher field effect mobility (µFE) are highly required toward the realization of next-generation displays. Among numerous types of TOS-TFTs, In2O3-based TFTs are the front-running candidate because they exhibit the highest µFE ≈100cm2V-1s-1. However, the device operation of In2O3 TFTs is unreliable; a large voltage shift occurs especially when negative gate bias is applied due to adsorption/desorption of gas molecules. Although passivation of the TFTs is used to overcome such instability, previously proposed passivation materials do not improve the reliability. Here, it is shown that the In2O3 TFTs passivated with Y2O3 and Er2O3 films are highly reliable and do not show threshold voltage shifts when applying gate bias. Positive and negative gate bias is applied to the In2O3 TFTs passivated with various insulating oxides and found that only the In2O3 TFTs passivated with Y2O3 and Er2O3 films do not exhibit threshold voltage shifts. It is observed that only the Y2O3 grew heteroepitaxially on the In2O3 crystal. This is the origin of the high reliability of the In2O3 TFTs passivated with Y2O3 and Er2O3 films. This finding accelerates the development of next-generation displays using high-mobility In2O3 TFTs.