You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy II1 Apr 2016PD30-09 A COMPARISON OF THE INCIDENCE AND LOCATION OF POSITIVE SURGICAL MARGIN AMONG OPEN, LAPAROSCOPIC, AND ROBOT-ASSISTED RADICAL PROSTATECTOMIES: A SINGLE INSTITUTIONAL ANALYSIS Atsushi Koizumi, Shintaro Narita, Taketoshi Nara, Koichiro Takayama, Kazuyuki Numakura, Hiroshi Tsuruta, Atsushi Maeno, Mitsuru Saito, Takamitsu Inoue, Shigeru Satoh, and Tomonori Habuchi Atsushi KoizumiAtsushi Koizumi More articles by this author , Shintaro NaritaShintaro Narita More articles by this author , Taketoshi NaraTaketoshi Nara More articles by this author , Koichiro TakayamaKoichiro Takayama More articles by this author , Kazuyuki NumakuraKazuyuki Numakura More articles by this author , Hiroshi TsurutaHiroshi Tsuruta More articles by this author , Atsushi MaenoAtsushi Maeno More articles by this author , Mitsuru SaitoMitsuru Saito More articles by this author , Takamitsu InoueTakamitsu Inoue More articles by this author , Shigeru SatohShigeru Satoh More articles by this author , and Tomonori HabuchiTomonori Habuchi More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.540AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES A positive surgical margin (PSM) after radical prostatectomy (RP) is associated with adverse oncological outcomes in patients with prostate cancer (PCa). Therefore, a negative surgical margin is one of the critical trifecta to be achieved during RP. Here, we investigate the differences in PSM rates and locations after RP among three operative procedures at a single institution. METHODS We retrospectively reviewed 478 patients who underwent RP without any neoadjuvant therapy at our institution between April 2004 and September 2015. All pathological diagnoses of RP specimens were evaluated by a single pathologist. We statistically compared PSM rates and locations after RP among three operative procedures, including open RP (ORP), laparoscopic RP (LRP), and robot assisted LRP (RALP), according to the International Society of Urological Pathology consensus conference on handling and staging of RP specimens. RESULTS The total numbers of patients in each group were 180 (37.3%) in ORP, 149 (30.8%) in LRP, and 154 (31.9%) in RALP. PSM rates in all patients were 23.5% (42/180), 17.6% (26/148), and 13.9% (21/151), respectively (P = 0.078). PSM rates after RALP were significantly lower than those after ORP (P = 0.028). In patients with stage =pT2 disease, PSM rates were the lowest for RALP (9.8%), intermediate for LRP (14.3%), and highest for ORP (14.4%). Among the patients treated with RALP, the PSMs were located in the apex (28.6%), in the lateral/posterolateral (28.6%) and bladder neck (42.9%). The most common site of PSM in patients treated with ORP and LRP was at the apex (45.2% and 48.0%, respectively). The rate of PSM in the bladder neck was higher in patients treated with RALP than in those treated with ORP and LRP (P < 0.001 and P = 0.087, respectively). CONCLUSIONS PSM rates were the lowest in patients with PCa treated with RALP compared with those treated with ORP and LRP (in all patients and in those with stage =pT2 disease). However, the bladder neck was the most common location of PSM in patients treated with RALP. Although RALP is a promising standard technique for local therapy in PCa, even from the point of margin status, it is necessary to pay attention to avoid a PSM, in particular, at the bladder neck. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e715 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Atsushi Koizumi More articles by this author Shintaro Narita More articles by this author Taketoshi Nara More articles by this author Koichiro Takayama More articles by this author Kazuyuki Numakura More articles by this author Hiroshi Tsuruta More articles by this author Atsushi Maeno More articles by this author Mitsuru Saito More articles by this author Takamitsu Inoue More articles by this author Shigeru Satoh More articles by this author Tomonori Habuchi More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...