Abstract Background To investigate the effect of positive psychology intervention on continuous quality improvement of nursing care for patients with intracranial tumor Material and Methods A total of 124 patients with intracranial tumor who received surgical treatment in our hospital from October 2020 to December 2021 were selected by convenience sampling method, and the patients were randomly divided into control group and intervention group.Patients in the control group received continuous quality improvement of postoperative routine care, and patients in the intervention group received positive psychological intervention based on postoperative routine care. Postoperative treatment compliance, subjective well-being and daily living ability were compared between the two groups Results The excellent compliance rate of intervention group was 95.15%, significantly higher than that of control group 83.87% (P < 0.05). The subjective well-being in intervention group (56.73±3.42) was significantly higher than that in control group (53.81±2.76) (P < 0.05). There was no significant difference in daily living ability score between 2 groups before intervention (P > 0.05). After intervention, the daily living ability score of the intervention group was (57.49±9.16), which was significantly higher than that of the control group and before intervention (P < 0.05). Conclusion Positive psychology intervention for patients with intracranial tumor can effectively improve the quality of nursing, increase the patient's treatment compliance, and improve the subjective well-being of patients and the ability of daily life is of great significance.