ABSTRACT In a recent paper, quantum vacuum was considered as a source of gravity, and the simplest, phenomenon, the gravitational polarization of the quantum vacuum by an immersed point-like body, was studied. In this paper, we have derived the effective gravitational charge density of the quantum vacuum, caused by two immersed point-like bodies. Among others, the obtained result proves that quantum vacuum can have regions with a negative effective gravitational charge density. Hence, quantum vacuum, the ‘ocean’ in which all matter of the Universe is immersed, acts as a complex fluid with a very variable gravitational charge density that might include both positive and negative densities; a crucial prediction that can be tested within the Solar system. In the general case of ${N \ge {\rm{3}}}$ point-like bodies, immersed in the quantum vacuum, the analytical solutions are not possible, and the use of numerical methods is inevitable. The key point is that an appropriate numerical method, for the calculation of the effective gravitational charge density of the quantum vacuum induced by N immersed bodies, might be crucial in description of galaxies, without the involvement of dark matter or a modification of gravity. The development of such a valuable numerical method, is not possible, without a previous (and in this study achieved) understanding of the impact of a two-body system.