Portosystemic Vascular Anomalies Research Articles

Evaluation of twelve-hour preprandial and two-hour postprandial serum bile acids concentrations for diagnosis of hepatobiliary disease in dogs

Summary In samples collected from 170 dogs suspected of having hepatobiliary disease, preprandial serum bile acids (prsba) and postprandial serum bile acids (posba) concentrations were measured, using a spectrophotometric enzymatic method. Dogs were assigned to 8 disease groups and 1 control group on the basis of hepatic histopathologic findings. Pre- and postprandial sba concentrations and results of routine biochemical analyses (including total bilirubin, albumin, and bun concentrations, and serum alkaline phosphatase (alp), alanine transaminase (alt), and aspartate transaminase (ast) activities) were expressed, using 4 indices: sensitivity, specificity, positive predictive value, and negative predictive value. Single tests and combinations of tests in series were evaluated. For diagnosis of hepatobiliary disease, the specificity of prsba was 100% at values > 20 μmol/L and of posba was 100% at values > 25 μmol/L. Test combinations with the best sensitivity for diagnosing the following diseases were: prsba-posba for cirrhosis, portosystemic vascular anomaly, and glucocorticoid hepatopathy; prsba-posba or prsba-alp for cholestasis; prsba-posba or alt-ast for chronic hepatitis; prsba-alt for hepatic necrosis and passive congestion; and prsba-alp for neoplasia. Test combinations with the overall highest sensitivity and positive predictive value for the fewest number of tests were prsba-posba, and either prsba or posba combined with an enzyme activity (alt, ast, or alp). The overall test efficacy for prsba vs posba was nearly identical: for prsba, it was 82.4%, and for posba, it was 82.3%. On the basis of the results of this study, prsba > 20 μmol/L or posba > 25 μmol/L (measured by use of an enzymatic procedure) indicates histopathologic abnormalities of the hepatobiliary system or portosystemic vascular anastomosis. Seemingly, determination of sba concentrations can be used to indicate the propriety for hepatic biopsy. Pre-and postprandial serum bile acids concentrations should be evaluated in conjunction with routinely used hepatobiliary screening tests for best diagnostic advantage.

Reliability case history of an airborne air turbine starter : Tadashi Murata. IEEE Trans. Reliab.R-25, (5) 302 (Dec. 1976)

Clinical case presentations detail unique and clinically relevant anatomical features about the canine and feline stomach, intestines, pancreas, liver, spleen, and abdominal body wall. One of these cases discusses a congenital developmental disorder—portosystemic vascular anomaly—in the context of clinical anatomy, thereby also providing relevant developmental anatomy.

Removal of serum amylase in dogs and the influence of reticuloendothelial blockade

ARTICLESRemoval of serum amylase in dogs and the influence of reticuloendothelial blockadeNathan Hiatt, and George BonorrisNathan Hiatt, and George BonorrisPublished Online:01 Jan 1966https://doi.org/10.1152/ajplegacy.1966.210.1.133MoreSectionsPDF (1 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByDiagnostic Enzymology of Domestic AnimalsGlomerular Filtration Rate and Renal Volume in Dogs with Congenital Portosystemic Vascular Anomalies before and after Surgical LigationJournal of Veterinary Internal Medicine, Vol. 13, No. 5Serum amylase and isoamylase values in dogs with pancreatic diseaseVeterinary Research Communications, Vol. 14, No. 6The Diagnostic Significance of Increased Urinary and Serum Amylase Activity in Bitches with PyometraJournal of Veterinary Medicine Series A, Vol. 36, No. 1-10Renal Disposition of Amylase, Lipase, and Lysozyme in the Dog26 June 2016 | Veterinary Pathology, Vol. 25, No. 6Macroamylasaemia after treatment with hydroxyethyl starchEuropean Journal of Clinical Investigation, Vol. 7, No. 3Evaluation of experimental canine pancreatitisJournal of Surgical Research, Vol. 21, No. 4Clinical Enzymology19 October 2001 | FEBS Letters, Vol. 62, No. S1Biliary Amylase Output in Rats with Pancreatic Duct Obstruction and CCl4-IntoxicationProceedings of the Japan Academy, Vol. 49, No. 3Makroamylase als seltene Ursache der Hyperamylas�mieKlinische Wochenschrift, Vol. 50, No. 11Biliary Amylase Outputs in RatsProceedings of the Japan Academy, Vol. 48, No. 9 More from this issue > Volume 210Issue 1January 1966Pages 133-138 Copyright & PermissionsCopyright © 1966 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1966.210.1.133History Published online 1 January 1966 Published in print 1 January 1966 Metrics