Porokeratotic Eccrine Ostial And Dermal Duct Nevus Research Articles

Linear psoriasis with porokeratotic eccrine ostial and dermal duct nevus

Linear psoriasis is an uncommon form of psoriasis characterized by the linear distribution of the psoriatic lesions. It usually follows the lines of Blaschko with unilateral involvement. Poro keratotic eccrine ostial and dermal duct (PEODD) nevus is another rare dermatosis that follows Blaschko's line. The pathogenesis of linear psoriasis and PEODD nevus is unclear, but both could be best explained by a specific somatic mutation. Hence, it has been suggested that the mutation responsible for PEODD nevus would constitute a rare but critical psoriasis gene. In the literature, 1 case of linear psoriasis with PEODD nevus was reported, which may support this suggestion. This article describes another case of linear psoriasis and PEODD nevus. A 7-year-old boy had a 4-month history of multiple psoriasiform plaques, arranged in linear distribution, and had congenital linear hyperkeratotic papules and pits on the right side of his trunk and right arm.

Nevo poroqueratósico de los ostios y ductos ecrinos

Abstract—Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is considered to be a hamartoma of the sweat gland duct.We present the case of a one-month-old baby girl who presented from birth with an eruption following Blaschko’s lines on the limbs and trunk, with clear palmoplantar involvement. It was not accompanied by any other congenital defect, and the patient’s development was normal. The biopsy of one of the lesions showed findings typical of PEODDN.The pathology and immunohistochemistry techniques in this disorder seem to reveal that the epidermal invagination where the Vale column (similar to a cornoid lamella) is found is crossed by an apparently normal acrosyringium. Because of the distribution of the lesions and their sporadic appearance, the disorder seems to represent a genetic mosaicism.

Porokeratotic eccrine ostial and dermal duct nevus

A case of porokeratotic eccrine ostial and dermal duct nevus (PEODDN) affecting all 4 extremities is described. Clinically, palmo-plantar lesions resembled those of nevus comedonicus and the remaining lesions those of linear verrucous epidermal nevus. Histologically, all lesions were identical with cornoid lamellae in the eccrine ostia and epidermal ducts.